Identification of a Chemical Tool for the Orphan Nuclear Receptor FXR von Maloney, Patrick R, Parks, Derek J, Haffner, Curt D, Fivush, Adam M, Chandra, Gyan, Plunket, Kelli D, Creech, Katrina L, Moore, Linda B, Wilson, Joan G, Lewis, Michael C, Jones, Stacey A, Willson, Timothy M

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The PPARs:  From Orphan Receptors to Drug Discovery von Willson, Timothy M, Brown, Peter J, Sternbach, Daniel D, Henke, Brad R

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PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR γ AND METABOLIC DISEASE von Willson, Timothy M, Lambert, Millard H, Kliewer, Steven A

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The Human Nuclear Xenobiotic Receptor PXR: Structural Determinants of Directed Promiscuity von Watkins, Ryan E., Wisely, G. Bruce, Moore, Linda B., Collins, Jon L., Lambert, Millard H., Williams, Shawn P., Willson, Timothy M., Kliewer, Steven A., Redinbo, Matthew R.

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Peroxisome proliferator-activated receptor-δ, a regulator of oxidative capacity, fuel switching and cholesterol transport von FÜRNSINN, C, WILLSON, T. M, BRUNMAIR, B

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The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation von Ricote, Mercedes, Li, Andrew C, Willson, Timothy M, Kelly, Carolyn J, Glass, Christopher K

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Bile Acids: Natural Ligands for an Orphan Nuclear Receptor von Parks, Derek J., Blanchard, Steven G., Bledsoe, Randy K., Chandra, Gyan, Consler, Thomas G., Kliewer, Steven A., Stimmel, Julie B., Willson, Timothy M., Zavacki, Ann Marie, Moore, David D., Lehmann, Jürgen M.

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PPARβ/δ selectively induces differentiation and inhibits cell proliferation von Kim, D J, Bility, M T, Billin, A N, Willson, T M, Gonzalez, F J, Peters, J M

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Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-γ von Milburn, Michael V, Nolte, Robert T, Wisely, G. Bruce, Westin, Stefan, Cobb, Jeffery E, Lambert, Millard H, Kurokawa, Riki, Rosenfeld, Michael G, Willson, Timothy M, Glass, Christopher K

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Peroxisome Proliferator-activated Receptors and Hepatic Stellate Cell Activation von Miyahara, Takeo, Schrum, Laura, Rippe, Richard, Xiong, Shigang, Yee, Hal F., Motomura, Kenta, Anania, Frank A., Willson, Timothy M., Tsukamoto, Hidekazu

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Structural Determinants of Ligand Binding Selectivity between the Peroxisome Proliferator-Activated Receptors von Xu, H. Eric, Lambert, Millard H., Montana, Valerie G., Plunket, Kelli D., Moore, Linda B., Collins, Jon L., Oplinger, Jeffery A., Kliewer, Steven A., Gampe, Robert T., McKee, David D., Moore, John T., Willson, Timothy M.

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Interleukin-4-dependent production of PPAR-γ ligands in macrophages by 12/15-lipoxygenase von Glass, Christopher K, Huang, Jannet T, Welch, John S, Ricote, Mercedes, Binder, Christoph J, Willson, Timothy M, Kelly, Carolyn, Witztum, Joseph L, Funk, Colin D, Conrad, Douglas

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A new ligand for the peroxisome proliferator-activated receptor-γ (PPAR-γ), GW7845, inhibits rat mammary carcinogenesis von NANJOO SUH, YONGPING WANG, WILLIAMS, C. R, RISINGSONG, R, GILMER, T, WILLSON, T. M, SPORN, M. B

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The Structure−Activity Relationship between Peroxisome Proliferator-Activated Receptor γ Agonism and the Antihyperglycemic Activity of Thiazolidinediones von Willson, Timothy M, Cobb, Jeffery E, Cowan, David J, Wiethe, Robert W, Correa, Itzela D, Prakash, Shimoga R, Beck, Kelli D, Moore, Linda B, Kliewer, Steven A, Lehmann, Jürgen M

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Differential involvement of peroxisome-proliferator-activated receptors alpha and delta in fibrate and fatty-acid-mediated inductions of the gene encoding liver fatty-acid-binding... von Poirier, H, Niot, I, Monnot, M C, Braissant, O, Meunier-Durmort, C, Costet, P, Pineau, T, Wahli, W, Willson, T M, Besnard, P

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Nonsteroidal anti-inflammatory drugs and peroxisome proliferator-activated receptor-gamma agonists modulate immunostimulated processing of amyloid precursor protein through regulat... von Sastre, Magdalena, Dewachter, Ilse, Landreth, Gary E, Willson, Timothy M, Klockgether, Thomas, van Leuven, Fred, Heneka, Michael T

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Regulation of Multidrug Resistance-associated Protein 2 (ABCC2) by the Nuclear Receptors Pregnane X Receptor, Farnesoid X-activated Receptor, and Constitutive Androstane Receptor von Kast, Heidi R., Goodwin, Bryan, Tarr, Paul T., Jones, Stacey A., Anisfeld, Andrew M., Stoltz, Catherine M., Tontonoz, Peter, Kliewer, Steve, Willson, Timothy M., Edwards, Peter A.

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Structural Analyses Reveal Phosphatidyl Inositols as Ligands for the NR5 Orphan Receptors SF-1 and LRH- 1 von Krylova, Irina N., Sablin, Elena P., Moore, Jamie, Xu, Robert X., Waitt, Gregory M., MacKay, J. Andrew, Juzumiene, Dalia, Bynum, Jane M., Madauss, Kevin, Montana, Valerie, Lebedeva, Lioudmila, Suzawa, Miyuki, Williams, Jon D., Williams, Shawn P., Guy, Rodney K., Thornton, Joseph W., Fletterick, Robert J., Willson, Timothy M., Ingraham, Holly A.

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Synthetic LXR Ligand Inhibits the Development of Atherosclerosis in Mice von Joseph, Sean B., McKilligin, Elaine, Pei, Liming, Watson, Michael A., Collins, Alan R., Laffitte, Bryan A., Chen, Mingyi, Noh, Grace, Goodman, Joanne, Hagger, Graham N., Tran, Jonathan, Tippin, Tim K., Wang, Xuping, Lusis, Aldons J., Hsueh, Willa A., Law, Ronald E., Collins, Jon L., Willson, Timothy M., Tontonoz, Peter

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Crystal Structure of the Glucocorticoid Receptor Ligand Binding Domain Reveals a Novel Mode of Receptor Dimerization and Coactivator Recognition von Bledsoe, Randy K., Montana, Valerie G., Stanley, Thomas B., Delves, Chris J., Apolito, Christopher J., McKee, David D., Consler, Thomas G., Parks, Derek J., Stewart, Eugene L., Willson, Timothy M., Lambert, Millard H., Moore, John T., Pearce, Kenneth H., Xu, H.Eric

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