Multi-omics analysis identifies ATF4 as a key regulator of the mitochondrial stress response in mammals von Quirós, Pedro M, Prado, Miguel A, Zamboni, Nicola, D'Amico, Davide, Williams, Robert W, Finley, Daniel, Gygi, Steven P, Auwerx, Johan

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Systems Genetics of Metabolism: The Use of the BXD Murine Reference Panel for Multiscalar Integration of Traits von Andreux, Pénélope A., Williams, Evan G., Koutnikova, Hana, Houtkooper, Riekelt H., Champy, Marie-France, Henry, Hugues, Schoonjans, Kristina, Williams, Robert W., Auwerx, Johan

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Ethanol-Induced Behavioral Sensitization Alters the Synaptic Transcriptome and Exon Utilization in DBA/2J Mice von O'Brien, Megan A, Weston, Rory M, Sheth, Nihar U, Bradley, Steven, Bigbee, John, Pandey, Ashutosh, Williams, Robert W, Wolstenholme, Jennifer T, Miles, Michael F

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PONDR-FIT: A meta-predictor of intrinsically disordered amino acids von Xue, Bin, Dunbrack, Roland L., Williams, Robert W., Dunker, A. Keith, Uversky, Vladimir N.

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Murine gut microbiota is defined by host genetics and modulates variation of metabolic traits von McKnite, Autumn M, Perez-Munoz, Maria Elisa, Lu, Lu, Williams, Evan G, Brewer, Simon, Andreux, Pénélope A, Bastiaansen, John W M, Wang, Xusheng, Kachman, Stephen D, Auwerx, Johan, Williams, Robert W, Benson, Andrew K, Peterson, Daniel A, Ciobanu, Daniel C

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Functionally enigmatic genes: a case study of the brain ignorome von Pandey, Ashutosh K, Lu, Lu, Wang, Xusheng, Homayouni, Ramin, Williams, Robert W

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Reproducibility and replicability of rodent phenotyping in preclinical studies von Kafkafi, Neri, Agassi, Joseph, Chesler, Elissa J., Crabbe, John C., Crusio, Wim E., Eilam, David, Gerlai, Robert, Golani, Ilan, Gomez-Marin, Alex, Heller, Ruth, Iraqi, Fuad, Jaljuli, Iman, Karp, Natasha A., Morgan, Hugh, Nicholson, George, Pfaff, Donald W., Richter, S. Helene, Stark, Philip B., Stiedl, Oliver, Stodden, Victoria, Tarantino, Lisa M., Tucci, Valter, Valdar, William, Williams, Robert W., Würbel, Hanno, Benjamini, Yoav

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Metabolic Stress Modulates Alzheimer’s β-Secretase Gene Transcription via SIRT1-PPARγ-PGC-1 in Neurons von Wang, Ruishan, Li, Jing Jing, Diao, Shiyong, Kwak, Young-Don, Liu, Li, Zhi, Lianteng, Büeler, Hansruedi, Bhat, Narayan R., Williams, Robert W., Park, Edwards A., Liao, Francesca-Fang

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Mapping the genetic architecture of complex traits in experimental populations von Yang, Jian, Zhu, Jun, Williams, Robert W.

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Systems genetics in the rat HXB/BXH family identifies Tti2 as a pleiotropic quantitative trait gene for adult hippocampal neurogenesis and serum glucose von Senko, Anna N, Overall, Rupert W, Silhavy, Jan, Mlejnek, Petr, Malínská, Hana, Hüttl, Martina, Marková, Irena, Fabel, Klaus S, Lu, Lu, Stuchlik, Ales, Williams, Robert W, Pravenec, Michal, Kempermann, Gerd

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Reduced oxidative capacity in macrophages results in systemic insulin resistance von Jung, Saet-Byel, Choi, Min Jeong, Ryu, Dongryeol, Yi, Hyon-Seung, Lee, Seong Eun, Chang, Joon Young, Chung, Hyo Kyun, Kim, Yong Kyung, Kang, Seul Gi, Lee, Ju Hee, Kim, Koon Soon, Kim, Hyun Jin, Kim, Cuk-Seong, Lee, Chul-Ho, Williams, Robert W., Kim, Hail, Lee, Heung Kyu, Auwerx, Johan, Shong, Minho

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Variability and heritability of mouse brain structure: Microscopic MRI atlases and connectomes for diverse strains von Wang, Nian, Anderson, Robert J., Ashbrook, David G., Gopalakrishnan, Vivek, Park, Youngser, Priebe, Carey E., Qi, Yi, Laoprasert, Rick, Vogelstein, Joshua T., Williams, Robert W., Johnson, G. Allan

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Genetic Variation in the Social Environment Contributes to Health and Disease von Baud, Amelie, Mulligan, Megan K, Casale, Francesco Paolo, Ingels, Jesse F, Bohl, Casey J, Callebert, Jacques, Launay, Jean-Marie, Krohn, Jon, Legarra, Andres, Williams, Robert W, Stegle, Oliver

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Patients experiencing statin-induced myalgia exhibit a unique program of skeletal muscle gene expression following statin re-challenge von Elam, Marshall B, Majumdar, Gipsy, Mozhui, Khyobeni, Gerling, Ivan C, Vera, Santiago R, Fish-Trotter, Hannah, Williams, Robert W, Childress, Richard D, Raghow, Rajendra

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Joint mouse–human phenome-wide association to test gene function and disease risk von Wang, Xusheng, Pandey, Ashutosh K., Mulligan, Megan K., Williams, Evan G., Mozhui, Khyobeni, Li, Zhengsheng, Jovaisaite, Virginija, Quarles, L. Darryl, Xiao, Zhousheng, Huang, Jinsong, Capra, John A., Chen, Zugen, Taylor, William L., Bastarache, Lisa, Niu, Xinnan, Pollard, Katherine S., Ciobanu, Daniel C., Reznik, Alexander O., Tishkov, Artem V., Zhulin, Igor B., Peng, Junmin, Nelson, Stanley F., Denny, Joshua C., Auwerx, Johan, Lu, Lu, Williams, Robert W.

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Genetic architecture supports mosaic brain evolution and independent brain–body size regulation von Hager, Reinmar, Lu, Lu, Rosen, Glenn D., Williams, Robert W.

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Identifying gene function and module connections by the integration of multispecies expression compendia von Li, Hao, Rukina, Daria, David, Fabrice P A, Li, Terytty Yang, Oh, Chang-Myung, Gao, Arwen W, Katsyuba, Elena, Bou Sleiman, Maroun, Komljenovic, Andrea, Huang, Qingyao, Williams, Robert W, Robinson-Rechavi, Marc, Schoonjans, Kristina, Morgenthaler, Stephan, Auwerx, Johan

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Genetic loci and metabolic states associated with murine epigenetic aging von Mozhui, Khyobeni, Lu, Ake T, Li, Caesar Z, Haghani, Amin, Sandoval-Sierra, Jose Vladimir, Wu, Yibo, Williams, Robert W, Horvath, Steve

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Genetic Polymorphisms Affect Mouse and Human Trace Amine-Associated Receptor 1 Function von Shi, Xiao, Walter, Nicole A R, Harkness, John H, Neve, Kim A, Williams, Robert W, Lu, Lu, Belknap, John K, Eshleman, Amy J, Phillips, Tamara J, Janowsky, Aaron

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Bayesian association scan reveals loci associated with human lifespan and linked biomarkers von McDaid, Aaron F., Joshi, Peter K., Porcu, Eleonora, Komljenovic, Andrea, Li, Hao, Sorrentino, Vincenzo, Litovchenko, Maria, Bevers, Roel P. J., Rüeger, Sina, Reymond, Alexandre, Bochud, Murielle, Deplancke, Bart, Williams, Robert W., Robinson-Rechavi, Marc, Paccaud, Fred, Rousson, Valentin, Auwerx, Johan, Wilson, James F., Kutalik, Zoltán

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