VPS34 complexes from a structural perspective von Ohashi, Yohei, Tremel, Shirley, Williams, Roger L.

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The emerging shape of the ESCRT machinery von Williams, Roger L, Urbé, Sylvie

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Synergy in activating class I PI3Ks von Burke, John E., Williams, Roger L.

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Activation of GCN2 by the ribosomal P-stalk von Inglis, Alison J., Masson, Glenn R., Shao, Sichen, Perisic, Olga, McLaughlin, Stephen H., Hegde, Ramanujan S., Williams, Roger L.

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PIKKs — the solenoid nest where partners and kinases meet von Baretić, Domagoj, Williams, Roger L.

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Structure and flexibility of the endosomal Vps34 complex reveals the basis of its function on membranes von Rostislavleva, Ksenia, Soler, Nicolas, Ohashi, Yohei, Zhang, Lufei, Pardon, Els, Burke, John E., Masson, Glenn R., Johnson, Chris, Steyaert, Jan, Ktistakis, Nicholas T., Williams, Roger L.

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Oncogenic mutations mimic and enhance dynamic events in the natural activation of phosphoinositide 3-kinase p110α (PIK3CA) von Burke, John E, Perisic, Olga, Masson, Glenn R, Vadas, Oscar, Williams, Roger L

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Structure of Lipid Kinase p110β/p85β Elucidates an Unusual SH2-Domain-Mediated Inhibitory Mechanism von Zhang, Xuxiao, Vadas, Oscar, Perisic, Olga, Anderson, Karen E., Clark, Jonathan, Hawkins, Phillip T., Stephens, Len R., Williams, Roger L.

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The Cargo Receptor NDP52 Initiates Selective Autophagy by Recruiting the ULK Complex to Cytosol-Invading Bacteria von Ravenhill, Benjamin J., Boyle, Keith B., von Muhlinen, Natalia, Ellison, Cara J., Masson, Glenn R., Otten, Elsje G., Foeglein, Agnes, Williams, Roger, Randow, Felix

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Structural Mechanisms of PTEN Regulation von Masson, Glenn R., Williams, Roger L.

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Immunomodulatory Role of the Extracellular Matrix Within the Liver Disease Microenvironment von McQuitty, Claire E., Williams, Roger, Chokshi, Shilpa, Urbani, Luca

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The ribosomal P-stalk couples amino acid starvation to GCN2 activation in mammalian cells von Harding, Heather P, Ordonez, Adriana, Allen, Felicity, Parts, Leopold, Inglis, Alison J, Williams, Roger L, Ron, David

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Architecture of human Rag GTPase heterodimers and their complex with mTORC1 von Anandapadamanaban, Madhanagopal, Masson, Glenn R, Perisic, Olga, Berndt, Alex, Kaufman, Jonathan, Johnson, Chris M, Santhanam, Balaji, Rogala, Kacper B, Sabatini, David M, Williams, Roger L

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Unsaturation, curvature and charge: effects of membrane parameters on PIK3C3/VPS34-containing complexes von Ohashi, Yohei, Tremel, Shirley, Williams, Roger L.

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The intrinsically disordered tails of PTEN and PTEN-L have distinct roles in regulating substrate specificity and membrane activity von Masson, Glenn R, Perisic, Olga, Burke, John E, Williams, Roger L

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Tor forms a dimer through an N-terminal helical solenoid with a complex topology von Baretić, Domagoj, Berndt, Alex, Ohashi, Yohei, Johnson, Christopher M., Williams, Roger L.

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The structural basis for mTOR function von Baretić, Domagoj, Williams, Roger L.

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Regulation of PI3K by PKC and MARCKS: Single-Molecule Analysis of a Reconstituted Signaling Pathway von Ziemba, Brian P., Burke, John E., Masson, Glenn, Williams, Roger L., Falke, Joseph J.

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5‑(4,6-Dimorpholino-1,3,5-triazin-2-yl)-4-(trifluoromethyl)­pyridin-2-amine (PQR309), a Potent, Brain-Penetrant, Orally Bioavailable, Pan-Class I PI3K/mTOR Inhibitor as Clinical Ca... von Beaufils, Florent, Cmiljanovic, Natasa, Cmiljanovic, Vladimir, Bohnacker, Thomas, Melone, Anna, Marone, Romina, Jackson, Eileen, Zhang, Xuxiao, Sele, Alexander, Borsari, Chiara, Mestan, Jürgen, Hebeisen, Paul, Hillmann, Petra, Giese, Bernd, Zvelebil, Marketa, Fabbro, Doriano, Williams, Roger L, Rageot, Denise, Wymann, Matthias P

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Structural basis for activation and inhibition of class I phosphoinositide 3-kinases von Vadas, Oscar, Burke, John E, Zhang, Xuxiao, Berndt, Alex, Williams, Roger L

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