Developing a Tanshinone IIA Memetic by Targeting MIOS to Regulate mTORC1 and Autophagy in Glioblastoma von Shinhmar, Sonia, Schaf, Judith, Lloyd Jones, Katie, Pardo, Olivier E, Beesley, Philip, Williams, Robin S B

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Mechanisms of action for the medium-chain triglyceride ketogenic diet in neurological and metabolic disorders von Augustin, Katrin, Khabbush, Aziza, Williams, Sophie, Eaton, Simon, Orford, Michael, Cross, J Helen, Heales, Simon J R, Walker, Matthew C, Williams, Robin S B

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A common mechanism of action for three mood-stabilizing drugs von Mudge, Anne W, Williams, Robin S. B, Cheng, Lili, Harwood, Adrian J

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Enhanced Sestrin expression through Tanshinone 2A treatment improves PI3K-dependent inhibition of glioma growth von Schaf, Judith, Shinhmar, Sonia, Zeng, Qingyu, Pardo, Olivier E., Beesley, Philip, Syed, Nelofer, Williams, Robin S. B.

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Genetic control of lithium sensitivity and regulation of inositol biosynthetic genes von King, Jason, Keim, Melanie, Teo, Regina, Weening, Karin E, Kapur, Mridu, McQuillan, Karina, Ryves, Jonathan, Rogers, Ben, Dalton, Emma, Williams, Robin S B, Harwood, Adrian J

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RpkA, a highly conserved GPCR with a lipid kinase domain, has a role in phagocytosis and anti-bacterial defense von Riyahi, Tanja Y, Frese, Frederike, Steinert, Michael, Omosigho, Napoleon N, Glöckner, Gernot, Eichinger, Ludwig, Orabi, Benoit, Williams, Robin S B, Noegel, Angelika A

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Structural basis of AMPA receptor inhibition by trans‐4‐butylcyclohexane carboxylic acid von Yelshanskaya, Maria V., Singh, Appu K., Narangoda, Chamali, Williams, Robin S.B., Kurnikova, Maria G., Sobolevsky, Alexander I.

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Investigating the effect of emetic compounds on chemotaxis in Dictyostelium identifies a non-sentient model for bitter and hot tastant research von Robery, Steven, Mukanowa, Janina, Percie du Sert, Nathalie, Andrews, Paul L R, Williams, Robin S B

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Gamma secretase orthologs are required for lysosomal activity and autophagic degradation in Dictyostelium discoideum, independent of PSEN (presenilin) proteolytic function von Sharma, Devdutt, Otto, Grant, Warren, Eleanor C., Beesley, Philip, King, Jason S., Williams, Robin S. B.

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Phytocannabinoid‐dependent mTORC1 regulation is dependent upon inositol polyphosphate multikinase activity von Damstra‐Oddy, Joseph L., Warren, Eleanor C., Perry, Christopher J., Desfougères, Yann, Fitzpatrick, John‐Mark K., Schaf, Judith, Costelloe, Lisa, Hind, William, Downer, Eric J., Saiardi, Adolfo, Williams, Robin S.B.

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Perampanel and decanoic acid show synergistic action against AMPA receptors and seizures von Augustin, Katrin, Williams, Sophie, Cunningham, Mark, Devlin, Anita M., Friedrich, Maximilian, Jayasekera, Ashan, Hussain, Mohammed A., Holliman, Damian, Mitchell, Patrick, Jenkins, Alistair, Chen, Philip E., Walker, Matthew C., Williams, Robin S.B.

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Diacylglycerol kinase (DGKA) regulates the effect of the epilepsy and bipolar disorder treatment valproic acid in Dictyostelium discoideum von Kelly, Elizabeth, Sharma, Devdutt, Wilkinson, Christopher J, Williams, Robin S B

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Inhibition of long‐term potentiation by valproic acid through modulation of cyclic AMP von Chang, Pishan, Chandler, Kate E., Williams, Robin S.B., Walker, Matthew C.

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A new mechanism for cannabidiol in regulating the one‐carbon cycle and methionine levels in Dictyostelium and in mammalian epilepsy models von Perry, Christopher J., Finch, Paul, Müller‐Taubenberger, Annette, Leung, Kit‐Yi, Warren, Eleanor C., Damstra‐Oddy, Joseph, Sharma, Devdutt, Patra, Pabitra H., Glyn, Sarah, Boberska, Joanna, Stewart, Balint, Baldwin, Amy, Piscitelli, Fabiana, Harvey, Robert J., Harwood, Adrian, Thompson, Christopher, Claus, Sandrine P., Greene, Nicholas D.E., McNeish, Alister J., Williams, Claire M., Whalley, Benjamin J., Williams, Robin S.B.

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All You Need Is Fats-for Seizure Control: Using Amoeba to Advance Epilepsy Research von Warren, Eleanor C, Walker, Matthew C, Williams, Robin S B

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Decanoic Acid Stimulates Autophagy in D. discoideum von Warren, Eleanor C., Kramar, Pavol, Lloyd-Jones, Katie, Williams, Robin S. B.

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Attenuation of Phospholipid Signaling Provides a Novel Mechanism for the Action of Valproic Acid von Xu, Xuehua, Müller-Taubenberger, Annette, Adley, Kathryn E, Pawolleck, Nadine, Lee, Vivian W Y, Wiedemann, Claudia, Sihra, Talvinder S, Maniak, Markus, Jin, Tian, Williams, Robin S B

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Curcumin and derivatives function through protein phosphatase 2A and presenilin orthologues in Dictyostelium discoideum von Cocorocchio, Marco, Baldwin, Amy J, Stewart, Balint, Kim, Lou, Harwood, Adrian J, Thompson, Christopher R L, Andrews, Paul L R, Williams, Robin S B

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Medium-Chain Fatty Acids Rescue Motor Function and Neuromuscular Junction Degeneration in a Drosophila Model of Amyotrophic Lateral Sclerosis von Dunn, Ella, Steinert, Joern R., Stone, Aelfwin, Sahota, Virender, Williams, Robin S. B., Snowden, Stuart, Augustin, Hrvoje

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Quantitative determination of SLC2A1 variant functional effects in GLUT1 deficiency syndrome von Tayebi, Naeimeh, Leon‐Ricardo, Brian, McCall, Kevin, Mehinovic, Elvisa, Engelstad, Kristin, Huynh, Vincent, Turner, Tychele N., Weisenberg, Judy, Thio, Liu L., Hruz, Paul, Williams, Robin S. B., De Vivo, Darryl C., Petit, Vincent, Haller, Gabe, Gurnett, Christina A.

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