Abstract A079: Glutamine antagonist prodrug JHU083 reprograms immunosuppressive tumor-associated macrophages to drive tumor immunity in urologic cancers von Praharaj, Monali, Shen, Fan, Lee, Alex J., Zhao, Liang, Nirschl, Thomas R., Wang, Xiaoxu, Theodros, Debebe, Singh, Alok K., Williams, Raekwon A., Sena, Laura A., Thompson, Elizabeth A., Tam, Ada, Yegnasubramanian, Srinivasan, Pearce, Edward J., Leone, Robert D., Alt, Jesse, Rais, Rana, Slusher, Barbara S., Pardoll, Drew M., Powell, Jonathan D., Zarif, Jelani C.

Volltext

Abstract 6432: Glutamine antagonist prodrug JHU083 reprograms immunosuppressive tumor-associated macrophages (TAMs) to drive tumor immunity in urologic cancers von Praharaj, Monali, Shen, Fan, Lee, Alex J., Zhao, Liang, Nirschl, Thomas, Wang, Xiaoxu, Theodros, Debebe, Singh, Alok K., Williams, Raekwon A., Sena, Laura A., Thompson, Elizabeth A., Tam, Ada, Yegnasubramanian, Srinivasan, Pearce, Edward J., Leone, Robert D., Alt, Jesse, Rais, Rana, Slusher, Barbara S., Pardoll, Andrew M., Powell, Jonathan D., Zarif, Jelani C.

Volltext

Abstract 2115: Glutamine blockade via prodrug JHU083 reprograms immunosuppressive tumor associated macrophages (TAMs) and drives tumor immunity in urologic cancers von Praharaj, Monali, Shen, Fan, Zhao, Liang, Nirschl, Thomas R., Sena, Laura, Singh, Alok K., Theodros, Debebe, Wang, Xiaoxu, Williams, Raekwon A., Thompson, Elizabeth, Tam, Ada, Yegnasubramanian, Srinivasan, Leone, Robert D., Al, Jesse, Rais, Rana, Slusher, Barbara S., Pardoll, Drew M., Powell, Jonathan D., Zarif, Jelani C.

Volltext