Compound C/Dorsomorphin: Its Use and Misuse as an AMPK Inhibitor von Dasgupta, Biplab, Seibel, William

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Small-molecule inhibitors targeting G-protein–coupled Rho guanine nucleotide exchange factors von Shang, Xun, Marchioni, Fillipo, Evelyn, Chris R., Sipes, Nisha, Zhou, Xuan, Seibel, William, Wortman, Matthew, Zheng, Yi

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Chaetocin-mediated SUV39H1 inhibition targets stemness and oncogenic networks of diffuse midline gliomas and synergizes with ONC201 von Xin, Dazhuan Eric, Liao, Yunfei, Rao, Rohit, Ogurek, Sean, Sengupta, Soma, Xin, Mei, Bayat, Arman Esshaghi, Seibel, William L, Graham, Richard T, Koschmann, Carl, Lu, Q Richard

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Small-Molecule Targeting of Proliferating Cell Nuclear Antigen Chromatin Association Inhibits Tumor Cell Growth von Tan, Zongqing, Wortman, Matthew, Dillehay, Kelsey L., Seibel, William L., Evelyn, Chris R., Smith, Shanna J., Malkas, Linda H., Zheng, Yi, Lu, Shan, Dong, Zhongyun

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A novel small molecule chaperone of rod opsin and its potential therapy for retinal degeneration von Chen, Yuanyuan, Chen, Yu, Jastrzebska, Beata, Golczak, Marcin, Gulati, Sahil, Tang, Hong, Seibel, William, Li, Xiaoyu, Jin, Hui, Han, Yong, Gao, Songqi, Zhang, Jianye, Liu, Xujie, Heidari-Torkabadi, Hossein, Stewart, Phoebe L., Harte, William E., Tochtrop, Gregory P., Palczewski, Krzysztof

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Ciprofloxacin is an inhibitor of the Mcm2-7 replicative helicase von Simon, Nicholas, Bochman, Matthew L, Seguin, Sandlin, Brodsky, Jeffrey L, Seibel, William L, Schwacha, Anthony

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New substituted 4H-chromenes as anticancer agents von Patil, Shivaputra A., Wang, Jin, Li, Xiaochen S., Chen, Jianjun, Jones, Terreia S., Hosni-Ahmed, Amira, Patil, Renukadevi, Seibel, William L., Li, Wei, Miller, Duane D.

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Small-molecule-induced epigenetic rejuvenation promotes SREBP condensation and overcomes barriers to CNS myelin regeneration von Liu, Xuezhao, Xin, Dazhuan Eric, Zhong, Xiaowen, Zhao, Chuntao, Li, Zhidan, Zhang, Liguo, Dourson, Adam J., Lee, Lindsay, Mishra, Shreya, Bayat, Arman E., Nicholson, Eva, Seibel, William L., Yan, Bingfang, Mason, Joel, Turner, Bradley J., Gonsalvez, David G., Ong, William, Chew, Sing Yian, Ghosh, Balaram, Yoon, Sung Ok, Xin, Mei, He, Zhigang, Tchieu, Jason, Wegner, Michael, Nave, Klaus-Armin, Franklin, Robin J.M., Dutta, Ranjan, Trapp, Bruce D., Hu, Ming, Smith, Matthew A., Jankowski, Michael P., Barton, Samantha K., He, Xuelian, Lu, Q. Richard

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Combined Rational Design and a High Throughput Screening Platform for Identifying Chemical Inhibitors of a Ras-activating Enzyme von Evelyn, Chris R., Biesiada, Jacek, Duan, Xin, Tang, Hong, Shang, Xun, Papoian, Ruben, Seibel, William L., Nelson, Sandra, Meller, Jaroslaw, Zheng, Yi

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Targeted inhibition of STAT/TET1 axis as a therapeutic strategy for acute myeloid leukemia von Jiang, Xi, Hu, Chao, Ferchen, Kyle, Nie, Ji, Cui, Xiaolong, Chen, Chih-Hong, Cheng, Liting, Zuo, Zhixiang, Seibel, William, He, Chunjiang, Tang, Yixuan, Skibbe, Jennifer R., Wunderlich, Mark, Reinhold, William C., Dong, Lei, Shen, Chao, Arnovitz, Stephen, Ulrich, Bryan, Lu, Jiuwei, Weng, Hengyou, Su, Rui, Huang, Huilin, Wang, Yungui, Li, Chenying, Qin, Xi, Mulloy, James C., Zheng, Yi, Diao, Jiajie, Jin, Jie, Li, Chong, Liu, Paul P., He, Chuan, Chen, Yuan, Chen, Jianjun

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IODVA1, a guanidinobenzimidazole derivative, targets Rac activity and Ras-driven cancer models von Gasilina, Anjelika, Premnauth, Gurdat, Gurjar, Purujit, Biesiada, Jacek, Hegde, Shailaja, Milewski, David, Ma, Gang, Kalin, Tanya V, Merino, Edward, Meller, Jarek, Seibel, William, Cancelas, José A, Vinnedge, Lisa Privette, Nassar, Nicolas N

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Inhibition of the growth factor MDK/midkine by a novel small molecule compound to treat non-small cell lung cancer von Hao, Huifang, Maeda, Yutaka, Fukazawa, Takuya, Yamatsuji, Tomoki, Takaoka, Munenori, Bao, Xiao-Hong, Matsuoka, Junji, Okui, Tatsuo, Shimo, Tsuyoshi, Takigawa, Nagio, Tomono, Yasuko, Nakajima, Motowo, Fink-Baldauf, Iris M, Nelson, Sandra, Seibel, William, Papoian, Ruben, Whitsett, Jeffrey A, Naomoto, Yoshio

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Identification of Novel Bisbenzimidazole Derivatives as Anticancer Vacuolar (H⁺)-ATPase Inhibitors von Patil, Renukadevi, Kulshrestha, Arpita, Tikoo, Anjali, Fleetwood, Sara, Katara, Gajendra, Kolli, Bala, Seibel, William, Gilman-Sachs, Alice, Patil, Shivaputra A, Beaman, Kenneth D

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Hits of a high-throughput screen identify the hydrophobic pocket of autotaxin/lysophospholipase D as an inhibitory surface von Fells, James I, Lee, Sue Chin, Fujiwara, Yuko, Norman, Derek D, Lim, Keng Gat, Tsukahara, Ryoko, Liu, Jianxiong, Patil, Renukadevi, Miller, Duane D, Kirby, R Jason, Nelson, Sandra, Seibel, William, Papoian, Ruben, Parrill, Abby L, Baker, Daniel L, Bittman, Robert, Tigyi, Gabor

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Author Correction: Targeted inhibition of STAT/TET1 axis as a therapeutic strategy for acute myeloid leukemia von Jiang, Xi, Hu, Chao, Ferchen, Kyle, Nie, Ji, Cui, Xiaolong, Chen, Chih-Hong, Cheng, Liting, Zuo, Zhixiang, Seibel, William, He, Chunjiang, Tang, Yixuan, Skibbe, Jennifer R., Wunderlich, Mark, Reinhold, William C., Dong, Lei, Shen, Chao, Arnovitz, Stephen, Ulrich, Bryan, Lu, Jiuwei, Weng, Hengyou, Su, Rui, Huang, Huilin, Wang, Yungui, Li, Chenying, Qin, Xi, Mulloy, James C., Zheng, Yi, Diao, Jiajie, Jin, Jie, Li, Chong, Liu, Paul P., He, Chuan, Chen, Yuan, Chen, Jianjun

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A novel, soluble compound, C25, sensitizes to TRAIL-induced apoptosis through upregulation of DR5 expression von James, Michael A, Seibel, William L, Kupert, Elena, Hu, Xiao X, Potharla, Vishwakanth Y, Anderson, Marshall W

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Extending matrix-assisted laser desorption/ionization triple quadrupole mass spectrometry enzyme screening assays to targets with small molecule substrates von Rathore, Rakesh, Corr, Jay J., Lebre, Daniel T., Seibel, William L., Greis, Kenneth D.

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Target validation and structure–activity analysis of a series of novel PCNA inhibitors von Dillehay, Kelsey L., Seibel, William L., Zhao, Daoli, Lu, Shan, Dong, Zhongyun

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Development of a Small-Molecule Screening Method for Inhibitors of Cellular Response to Myostatin and Activin A von Cash, Jennifer N., Angerman, Elizabeth B., Kirby, R. Jason, Merck, Lisa, Seibel, William L., Wortman, Matthew D., Papoian, Ruben, Nelson, Sandra, Thompson, Thomas B.

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Structure-Activity Relationship Analysis of Analogs of Rhosin, a RhoA Inhibitor, Reveals a New Generation of Improved Antiplatelet Agents von Dandamudi, Akhila, Seibel, William, Akbar, Huzoor, Zheng, Yi

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