Computational prediction of formulation strategies for beyond-rule-of-5 compounds von Bergström, Christel A.S., Charman, William N., Porter, Christopher J.H.

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50 years of oral lipid-based formulations: Provenance, progress and future perspectives von Feeney, Orlagh M., Crum, Matthew F., McEvoy, Claire L., Trevaskis, Natalie L., Williams, Hywel D., Pouton, Colin W., Charman, William N., Bergström, Christel A.S., Porter, Christopher J.H.

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Malarial dihydrofolate reductase as a paradigm for drug development against a resistance-compromised target von Yuthavong, Yongyuth, Tarnchompoo, Bongkoch, Vilaivan, Tirayut, Chitnumsub, Penchit, Kamchonwongpaisan, Sumalee, Charman, Susan A., McLennan, Danielle N., White, Karen L., Vivas, Livia, Bongard, Emily, Thongphanchang, Chawanee, Taweechai, Supannee, Vanichtanankul, Jarunee, Rattanajak, Roonglawan, Arwon, Uthai, Fantauzzi, Pascal, Yuvaniyama, Jirundon, Charman, William N., Matthews, David

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Lipids and lipid-based formulations: optimizing the oral delivery of lipophilic drugs von Porter, Christopher J. H., Trevaskis, Natalie L., Charman, William N.

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Relationship between Antimalarial Activity and Heme Alkylation for Spiro- and Dispiro-1,2,4-Trioxolane Antimalarials von Creek, Darren J, Charman, William N, Chiu, Francis C K, Prankerd, Richard J, Dong, Yuxiang, Vennerstrom, Jonathan L, Charman, Susan A

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Structure–Activity Relationship of the Antimalarial Ozonide Artefenomel (OZ439) von Dong, Yuxiang, Wang, Xiaofang, Kamaraj, Sriraghavan, Bulbule, Vivek J, Chiu, Francis C. K, Chollet, Jacques, Dhanasekaran, Manickam, Hein, Christopher D, Papastogiannidis, Petros, Morizzi, Julia, Shackleford, David M, Barker, Helena, Ryan, Eileen, Scheurer, Christian, Tang, Yuanqing, Zhao, Qingjie, Zhou, Lin, White, Karen L, Urwyler, Heinrich, Charman, William N, Matile, Hugues, Wittlin, Sergio, Charman, Susan A, Vennerstrom, Jonathan L

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Intestinal Lymph Flow, and Lipid and Drug Transport Scale Allometrically From Pre-clinical Species to Humans von Trevaskis, Natalie L., Lee, Given, Escott, Alistair, Phang, Kian Liun, Hong, Jiwon, Cao, Enyuan, Katneni, Kasiram, Charman, Susan A., Han, Sifei, Charman, William N., Phillips, Anthony R. J., Windsor, John A., Porter, Christopher J. H.

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Divergent effects of strontium and calcium‐sensing receptor positive allosteric modulators (calcimimetics) on human osteoclast activity von Diepenhorst, Natalie A, Leach, Katie, Keller, Andrew N, Rueda, Patricia, Cook, Anna E, Pierce, Tracie L, Nowell, Cameron, Pastoureau, Philippe, Sabatini, Massimo, Summers, Roger J, Charman, William N, Sexton, Patrick M, Christopoulos, Arthur, Langmead, Christopher J

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Antimalarial Activity of Pyrroloiminoquinones from the Australian Marine Sponge Zyzzya sp von Davis, Rohan A, Buchanan, Malcolm S, Duffy, Sandra, Avery, Vicky M, Charman, Susan A, Charman, William N, White, Karen L, Shackleford, David M, Edstein, Michael D, Andrews, Katherine T, Camp, David, Quinn, Ronald J

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Murine GPRC6A Mediates Cellular Responses to L-Amino Acids, but Not Osteocalcin Variants von Rueda, Patricia, Harley, Elizabeth, Lu, Yao, Stewart, Gregory D, Fabb, Stewart, Diepenhorst, Natalie, Cremers, Béatrice, Rouillon, Marie-Hélène, Wehrle, Isabelle, Geant, Anne, Lamarche, Gwladys, Leach, Katie, Charman, William N, Christopoulos, Arthur, Summers, Roger J, Sexton, Patrick M, Langmead, Christopher J

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Lipids, Lipophilic Drugs, and Oral Drug Delivery—Some Emerging Concepts von Charman, William N.

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Intestinal Bile Secretion Promotes Drug Absorption from Lipid Colloidal Phases via Induction of Supersaturation von Yeap, Yan Yan, Trevaskis, Natalie L, Quach, Tim, Tso, Patrick, Charman, William N, Porter, Christopher J. H

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Strategies to Address Low Drug Solubility in Discovery and Development von Williams, Hywel D., Trevaskis, Natalie L., Charman, Susan A., Shanker, Ravi M., Charman, William N., Pouton, Colin W., Porter, Christopher J.H.

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Susceptibility to lipase-mediated digestion reduces the oral bioavailability of danazol after administration as a medium-chain lipid-based microemulsion formulation von Porter, Christopher J H, Kaukonen, Ann Marie, Boyd, Ben J, Edwards, Glenn A, Charman, William N

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A Mouse Model to Evaluate the Impact of Species, Sex, and Lipid Load on Lymphatic Drug Transport von Trevaskis, Natalie L., Caliph, Suzanne M., Nguyen, Gary, Tso, Patrick, Charman, William N., Porter, Christopher J. H.

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Evaluation of the Impact of Surfactant Digestion on the Bioavailability of Danazol after Oral Administration of Lipidic Self-Emulsifying Formulations to Dogs von Cuiné, Jean F., McEvoy, Claire L., Charman, William N., Pouton, Colin W., Edwards, Glenn A., Benameur, Hassan, Porter, Christopher J.H.

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Increasing the proportional content of surfactant (cremophor EL) relative to lipid in self-emulsifying lipid-based formulations of danazol reduces oral bioavailability in beagle do... von CUINE, Jean F, CHARMAN, William N, POUTON, Colin W, EDWARDS, Glenn A, PORTER, Christopher J. H

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Synthesis and Biological Evaluation of Polysulfated Oligosaccharide Glycosides as Inhibitors of Angiogenesis and Tumor Growth von Johnstone, Ken D, Karoli, Tomislav, Liu, Ligong, Dredge, Keith, Copeman, Elizabeth, Li, Cai Ping, Davis, Kat, Hammond, Edward, Bytheway, Ian, Kostewicz, Edmund, Chiu, Francis C. K, Shackleford, David M, Charman, Susan A, Charman, William N, Harenberg, Job, Gonda, Thomas J, Ferro, Vito

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Pharmacological Insights Into Safety and Efficacy Determinants for the Development of Adenosine Receptor Biased Agonists in the Treatment of Heart Failure von Rueda, Patricia, Merlin, Jon, Chimenti, Stefano, Feletou, Michel, Paysant, Jerome, White, Paul J, Christopoulos, Arthur, Sexton, Patrick M, Summers, Roger J, Charman, William N, May, Lauren T, Langmead, Christopher J

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Lipid-based vehicles for the oral delivery of poorly water soluble drugs von Humberstone, Andrew J., Charman, William N.

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