Hybrid Vigor, Fetal Overgrowth, and Viability of Mice Derived by Nuclear Cloning and Tetraploid Embryo Complementation von Eggan, Kevin, Akutsu, Hidenori, Loring, Janet, Jackson-Grusby, Laurie, Klemm, Martina, William M. Rideout 3rd, Yanagimachi, Ryuzo, Jaenisch, Rudolf

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Lineage tracing reveals the phylodynamics, plasticity, and paths of tumor evolution von Yang, Dian, Jones, Matthew G., Naranjo, Santiago, Rideout, William M., Min, Kyung Hoi (Joseph), Ho, Raymond, Wu, Wei, Replogle, Joseph M., Page, Jennifer L., Quinn, Jeffrey J., Horns, Felix, Qiu, Xiaojie, Chen, Michael Z., Freed-Pastor, William A., McGinnis, Christopher S., Patterson, David M., Gartner, Zev J., Chow, Eric D., Bivona, Trever G., Chan, Michelle M., Yosef, Nir, Jacks, Tyler, Weissman, Jonathan S.

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The CD155/TIGIT axis promotes and maintains immune evasion in neoantigen-expressing pancreatic cancer von Freed-Pastor, William A., Lambert, Laurens J., Ely, Zackery A., Pattada, Nimisha B., Bhutkar, Arjun, Eng, George, Mercer, Kim L., Garcia, Ana P., Lin, Lin, Rideout, William M., Hwang, William L., Schenkel, Jason M., Jaeger, Alex M., Bronson, Roderick T., Westcott, Peter M.K., Hether, Tyler D., Divakar, Prajan, Reeves, Jason W., Deshpande, Vikram, Delorey, Toni, Phillips, Devan, Yilmaz, Omer H., Regev, Aviv, Jacks, Tyler

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Mismatch repair deficiency is not sufficient to elicit tumor immunogenicity von Westcott, Peter M. K., Muyas, Francesc, Hauck, Haley, Smith, Olivia C., Sacks, Nathan J., Ely, Zackery A., Jaeger, Alex M., Rideout, William M., Zhang, Daniel, Bhutkar, Arjun, Beytagh, Mary C., Canner, David A., Jaramillo, Grissel C., Bronson, Roderick T., Naranjo, Santiago, Jin, Abbey, Patten, J. J., Cruz, Amanda M., Shanahan, Sean-Luc, Cortes-Ciriano, Isidro, Jacks, Tyler

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CRISPR-mediated modeling and functional validation of candidate tumor suppressor genes in small cell lung cancer von Ng, Sheng Rong, Rideout, William M., Akama-Garren, Elliot H., Bhutkar, Arjun, Mercer, Kim L., Schenkel, Jason M., Bronson, Roderick T., Jacks, Tyler

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Deciphering the immunopeptidome in vivo reveals new tumour antigens von Jaeger, Alex M., Stopfer, Lauren E., Ahn, Ryuhjin, Sanders, Emma A., Sandel, Demi A., Freed-Pastor, William A., Rideout, William M., Naranjo, Santiago, Fessenden, Tim, Nguyen, Kim B., Winter, Peter S., Kohn, Ryan E., Westcott, Peter M. K., Schenkel, Jason M., Shanahan, Sean-Luc, Shalek, Alex K., Spranger, Stefani, White, Forest M., Jacks, Tyler

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A prime editor mouse to model a broad spectrum of somatic mutations in vivo von Ely, Zackery A., Mathey-Andrews, Nicolas, Naranjo, Santiago, Gould, Samuel I., Mercer, Kim L., Newby, Gregory A., Cabana, Christina M., Rideout, William M., Jaramillo, Grissel Cervantes, Khirallah, Jennifer M., Holland, Katie, Randolph, Peyton B., Freed-Pastor, William A., Davis, Jessie R., Kulstad, Zachary, Westcott, Peter M. K., Lin, Lin, Anzalone, Andrew V., Horton, Brendan L., Pattada, Nimisha B., Shanahan, Sean-Luc, Ye, Zhongfeng, Spranger, Stefani, Xu, Qiaobing, Sánchez-Rivera, Francisco J., Liu, David R., Jacks, Tyler

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MET Signaling in Colon Cancer Stem-like Cells Blunts the Therapeutic Response to EGFR Inhibitors von LURAGHI, Paolo, REATO, Gigliola, PERERA, Timothy, BERTOTTI, Andrea, TRUSOLINO, Livio, COMOGLIO, Paolo M, BOCCACCIO, Carla, CIPRIANO, Elia, SASSI, Francesco, ORZAN, Francesca, BIGATTO, Viola, DE BACCO, Francesca, MENIETTI, Elena, MAY HAN, RIDEOUT, William M

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Deciphering cell states and genealogies of human haematopoiesis von Weng, Chen, Yu, Fulong, Yang, Dian, Poeschla, Michael, Liggett, L. Alexander, Jones, Matthew G., Qiu, Xiaojie, Wahlster, Lara, Caulier, Alexis, Hussmann, Jeffrey A., Schnell, Alexandra, Yost, Kathryn E., Koblan, Luke W., Martin-Rufino, Jorge D., Min, Joseph, Hammond, Alessandro, Ssozi, Daniel, Bueno, Raphael, Mallidi, Hari, Kreso, Antonia, Escabi, Javier, Rideout, William M., Jacks, Tyler, Hormoz, Sahand, van Galen, Peter, Weissman, Jonathan S., Sankaran, Vijay G.

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Assessment of ABT-263 activity across a cancer cell line collection leads to a potent combination therapy for small-cell lung cancer von Faber, Anthony C., Farago, Anna F., Costa, Carlotta, Dastur, Anahita, Gomez-Caraballo, Maria, Robbins, Rebecca, Wagner, Bethany L., Rideout, William M., Jakubik, Charles T., Ham, Jungoh, Edelman, Elena J., Ebi, Hiromichi, Yeo, Alan T., Hata, Aaron N., Song, Youngchul, Patel, Neha U., March, Ryan J., Tam, Ah Ting, Milano, Randy J., Boisvert, Jessica L., Hicks, Mark A., Elmiligy, Sarah, Malstrom, Scott E., Rivera, Miguel N., Harada, Hisashi, Windle, Brad E., Ramaswamy, Sridhar, Benes, Cyril H., Jacks, Tyler, Engelman, Jeffrey A.

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A Modular Assembly Platform for Rapid Generation of DNA Constructs von Akama-Garren, Elliot H., Joshi, Nikhil S., Tammela, Tuomas, Chang, Gregory P., Wagner, Bethany L., Lee, Da-Yae, Rideout III, William M., Papagiannakopoulos, Thales, Xue, Wen, Jacks, Tyler

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Microenvironment-derived HGF overcomes genetically determined sensitivity to anti-MET drugs von Pennacchietti, Selma, Cazzanti, Manuela, Bertotti, Andrea, Rideout, 3rd, William M, Han, May, Gyuris, Jeno, Perera, Timothy, Comoglio, Paolo M, Trusolino, Livio, Michieli, Paolo

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Global loss of imprinting leads to widespread tumorigenesis in adult mice von Holm, Teresa M., Jackson-Grusby, Laurie, Brambrink, Tobias, Yamada, Yasuhiro, Rideout, William M., Jaenisch, Rudolf

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Correction of a Genetic Defect by Nuclear Transplantation and Combined Cell and Gene Therapy von Rideout, William M., Hochedlinger, Konrad, Kyba, Michael, Daley, George Q., Jaenisch, Rudolf

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Chimeric mouse tumor models reveal differences in pathway activation between ERBB family– and KRAS-dependent lung adenocarcinomas von Zhou, Yinghui, Rideout, William M, Zi, Tong, Bressel, Angela, Reddypalli, Shailaja, Rancourt, Rebecca, Woo, Jin-Kyeung, Horner, James W, Chin, Lynda, Chiu, M Isabel, Bosenberg, Marcus, Jacks, Tyler, Clark, Steven C, DePinho, Ronald A, Robinson, Murray O, Heyer, Joerg

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Spontaneous genomic alterations in a chimeric model of colorectal cancer enable metastasis and guide effective combinatorial therapy von Zhou, Yinghui, Rideout, 3rd, William M, Bressel, Angela, Yalavarthi, Sireesha, Zi, Tong, Potz, Darren, Farlow, Samuel, Brodeur, Joelle, Monti, Anthony, Reddipalli, Shailaja, Xiao, Qiurong, Bottega, Steve, Feng, Bin, Chiu, M Isabel, Bosenberg, Marcus, Heyer, Joerg

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Nuclear Cloning and Epigenetic Reprogramming of the Genome von Rideout, William M., Eggan, Kevin, Jaenisch, Rudolf

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Epigenetic Instability in ES Cells and Cloned Mice von Humpherys, David, Eggan, Kevin, Akutsu, Hidenori, Hochedlinger, Konrad, Rideout, William M., Biniszkiewicz, Detlev, Yanagimachi, Ryuzo, Jaenisch, Rudolf

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Generation of mice from wild-type and targeted ES cells by nuclear cloning von Rideout, William M., Wakayama, Teruhiko, Wutz, Anton, Eggan, Kevin, Jackson-Grusby, Laurie, Dausman, Jessica, Yanagimachi, Ryuzo, Jaenisch, Rudolf

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5-Methylcytosine as an Endogenous Mutagen in the Human LDL Receptor and p53 Genes von Rideout, William M., Coetzee, Gerhard A., Olumi, Aria F., Jones, Peter A.

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