The acidic pathway of bile acid synthesis: Not just an alternative pathway von Pandak, William M., Kakiyama, Genta

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The role of sphingosine 1‐phosphate receptor 2 in bile‐acid–induced cholangiocyte proliferation and cholestasis‐induced liver injury in mice von Wang, Yongqing, Aoki, Hiroaki, Yang, Jing, Peng, Kesong, Liu, Runping, Li, Xiaojiaoyang, Qiang, Xiaoyan, Sun, Lixin, Gurley, Emily C., Lai, Guanhua, Zhang, Luyong, Liang, Guang, Nagahashi, Masayuki, Takabe, Kazuaki, Pandak, William M., Hylemon, Phillip B., Zhou, Huiping

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Cholangiocyte‐derived exosomal long noncoding RNA H19 promotes cholestatic liver injury in mouse and humans von Li, Xiaojiaoyang, Liu, Runping, Huang, Zhiming, Gurley, Emily C., Wang, Xuan, Wang, Juan, He, Hongliang, Yang, Hu, Lai, Guanhua, Zhang, Luyong, Bajaj, Jasmohan S., White, Melanie, Pandak, William M., Hylemon, Phillip B., Zhou, Huiping

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Modulation of the fecal bile acid profile by gut microbiota in cirrhosis von Kakiyama, Genta, Pandak, William M, Gillevet, Patrick M, Hylemon, Phillip B, Heuman, Douglas M, Daita, Kalyani, Takei, Hajime, Muto, Akina, Nittono, Hiroshi, Ridlon, Jason M, White, Melanie B, Noble, Nicole A, Monteith, Pamela, Fuchs, Michael, Thacker, Leroy R, Sikaroodi, Masoumeh, Bajaj, Jasmohan S

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Bile acids as regulatory molecules von Hylemon, Phillip B., Zhou, Huiping, Pandak, William M., Ren, Shunlin, Gil, Gregorio, Dent, Paul

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Conjugated bile acid–activated S1P receptor 2 is a key regulator of sphingosine kinase 2 and hepatic gene expression von Nagahashi, Masayuki, Takabe, Kazuaki, Liu, Runping, Peng, Kesong, Wang, Xiang, Wang, Yun, Hait, Nitai C., Wang, Xuan, Allegood, Jeremy C., Yamada, Akimitsu, Aoyagi, Tomoyoshi, Liang, Jie, Pandak, William M., Spiegel, Sarah, Hylemon, Phillip B., Zhou, Huiping

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C/EBP homologous protein–induced loss of intestinal epithelial stemness contributes to bile duct ligation–induced cholestatic liver injury in mice von Liu, Runping, Li, Xiaojiaoyang, Huang, Zhiming, Zhao, Derrick, Ganesh, Bhagyalaxmi Sukka, Lai, Guanhua, Pandak, William M., Hylemon, Phillip B, Bajaj, Jasmohan S., Sanyal, Arun J., Zhou, Huiping

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Berberine inhibits HIV protease inhibitor-induced inflammatory response by modulating ER stress signaling pathways in murine macrophages von Zha, Weibin, Liang, Guang, Xiao, Jian, Studer, Elaine J, Hylemon, Phillip B, Pandak, Jr, William M, Wang, Guangji, Li, Xiaokun, Zhou, Huiping

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Conjugated bile acids promote cholangiocarcinoma cell invasive growth through activation of sphingosine 1‐phosphate receptor 2 von Liu, Runping, Zhao, Renping, Zhou, Xiqiao, Liang, Xiuyin, Campbell, Deanna J.W., Zhang, Xiaoxuan, Zhang, Luyong, Shi, Ruihua, Wang, Guangji, Pandak, William M., Sirica, Alphonse E., Hylemon, Phillip B., Zhou, Huiping

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Conjugated bile acids activate the sphingosine-1-phosphate receptor 2 in primary rodent hepatocytes von Studer, Elaine, Zhou, Xiqiao, Zhao, Renping, Wang, Yun, Takabe, Kazuaki, Nagahashi, Masayuki, Pandak, William M., Dent, Paul, Spiegel, Sarah, Shi, Ruihua, Xu, Weiren, Liu, Xuyuan, Bohdan, Pat, Zhang, Luyong, Zhou, Huiping, Hylemon, Phillip B.

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Colonic inflammation and secondary bile acids in alcoholic cirrhosis von Kakiyama, Genta, Hylemon, Phillip B, Zhou, Huiping, Pandak, William M, Heuman, Douglas M, Kang, Dae Joong, Takei, Hajime, Nittono, Hiroshi, Ridlon, Jason M, Fuchs, Michael, Gurley, Emily C, Wang, Yun, Liu, Runping, Sanyal, Arun J, Gillevet, Patrick M, Bajaj, Jasmohan S

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A simple and accurate HPLC method for fecal bile acid profile in healthy and cirrhotic subjects: validation by GC-MS and LC-MS[S] von Kakiyama, Genta, Muto, Akina, Takei, Hajime, Nittono, Hiroshi, Murai, Tsuyoshi, Kurosawa, Takao, Hofmann, Alan F., Pandak, William M., Bajaj, Jasmohan S.

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Insulin resistance dysregulates CYP7B1 leading to oxysterol accumulation: a pathway for NAFL to NASH transition von Kakiyama, Genta, Marques, Dalila, Martin, Rebecca, Takei, Hajime, Rodriguez-Agudo, Daniel, LaSalle, Sandra A., Hashiguchi, Taishi, Liu, Xiaoying, Green, Richard, Erickson, Sandra, Gil, Gregorio, Fuchs, Michael, Suzuki, Mitsuyoshi, Murai, Tsuyoshi, Nittono, Hiroshi, Hylemon, Phillip B., Zhou, Huiping, Pandak, William M.

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Insulin dysregulation drives mitochondrial cholesterol metabolite accumulation: initiating hepatic toxicity in nonalcoholic fatty liver disease von Minowa, Kei, Rodriguez-Agudo, Daniel, Suzuki, Mitsuyoshi, Muto, Yamato, Hirai, Saeko, Wang, Yaping, Su, Lianyong, Zhou, Huiping, Chen, Qun, Lesnefsky, Edward J., Mitamura, Kuniko, Ikegawa, Shigeo, Takei, Hajime, Nittono, Hiroshi, Fuchs, Michael, Pandak, William M., Kakiyama, Genta

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Mitochondrial Cholesterol Metabolites in a Bile Acid Synthetic Pathway Drive Nonalcoholic Fatty Liver Disease: A Revised "Two-Hit" Hypothesis von Kakiyama, Genta, Rodriguez-Agudo, Daniel, Pandak, William M

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StarD5: an ER stress protein regulates plasma membrane and intracellular cholesterol homeostasis von Rodriguez-Agudo, Daniel, Malacrida, Leonel, Kakiyama, Genta, Sparrer, Tavis, Fortes, Carolina, Maceyka, Michael, Subler, Mark A., Windle, Jolene J., Gratton, Enrico, Pandak, William M., Gil, Gregorio

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Alterations in gut microbial function following liver transplant von Bajaj, Jasmohan S., Kakiyama, Genta, Cox, I. Jane, Nittono, Hiroshi, Takei, Hajime, White, Melanie, Fagan, Andrew, Gavis, Edith A., Heuman, Douglas M., Gilles, Ho Chong, Hylemon, Phillip, Taylor‐Robinson, Simon D., Legido‐Quigley, Cristina, Kim, Min, Xu, Jin, Williams, Roger, Sikaroodi, Masoumeh, Pandak, William M., Gillevet, Patrick M.

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Inhibition of P-glycoprotein by HIV protease inhibitors increases intracellular accumulation of berberine in murine and human macrophages von Zha, Weibin, Wang, Guangji, Xu, Weiren, Liu, Xuyuan, Wang, Yun, Zha, Beth S, Shi, Jian, Zhao, Qijin, Gerk, Phillip M, Studer, Elaine, Hylemon, Phillip B, Pandak, Jr, William M, Zhou, Huiping

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StarD5 modulates B cell cholesterol synthesis and IgG1 plasma cell differentiation von Tharakan, Anuj, Rodriguez-Agudo, Daniel, Damle, Sheela, Kakiyama, Genta, Pandak, William M., Gil, Gregorio, Martin, Rebecca K.

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High Glucose Induces Lipid Accumulation via 25-Hydroxycholesterol DNA-CpG Methylation von Wang, Yaping, Chen, Lanming, Pandak, William M., Heuman, Douglas, Hylemon, Phillip B., Ren, Shunlin

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