Treating acute myeloid leukemia in the modern era: A primer von Blum, William G., Mims, Alice S.

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Tagraxofusp in Blastic Plasmacytoid Dendritic-Cell Neoplasm von Pemmaraju, Naveen, Lane, Andrew A, Sweet, Kendra L, Stein, Anthony S, Vasu, Sumithira, Blum, William, Rizzieri, David A, Wang, Eunice S, Duvic, Madeleine, Sloan, J. Mark, Spence, Sharon, Shemesh, Shay, Brooks, Christopher L, Balser, John, Bergstein, Ivan, Lancet, Jeffrey E, Kantarjian, Hagop M, Konopleva, Marina

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Expression and prognostic impact of lncRNAs in acute myeloid leukemia von Garzon, Ramiro, Volinia, Stefano, Papaioannou, Dimitrios, Nicolet, Deedra, Kohlschmidt, Jessica, Yan, Pearlly S, Mrózek, Krzysztof, Bucci, Donna, Carroll, Andrew J, Baer, Maria R, Wetzler, Meir, Carter, Thomas H, Powell, Bayard L, Kolitz, Jonathan E, Moore, Joseph O, Eisfeld, Ann-Kathrin, Blachly, James S, Blum, William, Caligiuri, Michael A, Stone, Richard M, Marcucci, Guido, Croce, Carlo M, Byrd, John C, Bloomfield, Clara D

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Preclinical activity of a novel CRM1 inhibitor in acute myeloid leukemia von Ranganathan, Parvathi, Yu, Xueyan, Na, Caroline, Santhanam, Ramasamy, Shacham, Sharon, Kauffman, Michael, Walker, Alison, Klisovic, Rebecca, Blum, William, Caligiuri, Michael, Croce, Carlo M., Marcucci, Guido, Garzon, Ramiro

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Outcome prediction by the 2022 European LeukemiaNet genetic-risk classification for adults with acute myeloid leukemia: an Alliance study von Mrózek, Krzysztof, Kohlschmidt, Jessica, Blachly, James S., Nicolet, Deedra, Carroll, Andrew J., Archer, Kellie J., Mims, Alice S., Larkin, Karilyn T., Orwick, Shelley, Oakes, Christopher C., Kolitz, Jonathan E., Powell, Bayard L., Blum, William G., Marcucci, Guido, Baer, Maria R., Uy, Geoffrey L., Stock, Wendy, Byrd, John C., Eisfeld, Ann-Kathrin

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Why the stagnation in effective therapy for MDS? von Blum, William, MD

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Entospletinib in Combination with Induction Chemotherapy in Previously Untreated Acute Myeloid Leukemia: Response and Predictive Significance of HOXA9 and MEIS1 Expression von Walker, Alison R, Byrd, John C, Blachly, James S, Bhatnagar, Bhavana, Mims, Alice S, Orwick, Shelley, Lin, Tara L, Crosswell, Howland E, Zhang, Danjie, Minden, Mark D, Munugalavadla, Veerendra, Long, Lauren, Liu, Jinfeng, Pan, Yang, Oellerich, Thomas, Serve, Hubert, Rao, Arati V, Blum, William G

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Autologous transplantation for Philadelphia chromosome-positive acute lymphoblastic leukemia achieves outcomes similar to allogeneic transplantation: results of CALGB Study 10001 (... von Wetzler, Meir, Watson, Dorothy, Stock, Wendy, Koval, Gregory, Mulkey, Flora A, Hoke, Eva E, McCarty, John M, Blum, William G, Powell, Bayard L, Marcucci, Guido, Bloomfield, Clara D, Linker, Charles A, Larson, Richard A

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Clinical response and miR-29b predictive significance in older AML patients treated with a 10-day schedule of decitabine von Blum, William, Garzon, Ramiro, Klisovic, Rebecca B, Schwind, Sebastian, Walker, Alison, Geyer, Susan, Liu, Shujun, Havelange, Violaine, Becker, Heiko, Schaaf, Larry, Mickle, Jon, Devine, Hollie, Kefauver, Cheryl, Devine, Steven M, Chan, Kenneth K, Heerema, Nyla A, Bloomfield, Clara D, Grever, Michael R, Byrd, John C, Villalona-Calero, Miguel, Croce, Carlo M, Marcucci, Guido

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MicroRNA-29b induces global DNA hypomethylation and tumor suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1 von Garzon, Ramiro, Liu, Shujun, Fabbri, Muller, Liu, Zhongfa, Heaphy, Catherine E.A., Callegari, Elisa, Schwind, Sebastian, Pang, Jiuxia, Yu, Jianhua, Muthusamy, Natarajan, Havelange, Violaine, Volinia, Stefano, Blum, William, Rush, Laura J., Perrotti, Danilo, Andreeff, Michael, Bloomfield, Clara D., Byrd, John C., Chan, Kenneth, Wu, Lai-Chu, Croce, Carlo M., Marcucci, Guido

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Targeted Delivery of microRNA-29b by Transferrin-Conjugated Anionic Lipopolyplex Nanoparticles: A Novel Therapeutic Strategy in Acute Myeloid Leukemia von XIAOMENG HUANG, SCHWIND, Sebastian, BLUM, William, PERROTTI, Danilo, BYRD, John C, BLOOMFIELD, Clara D, CALIGIURI, Michael A, LEE, Robert J, GARZON, Ramiro, MUTHUSAMY, Natarajan, LEE, Ly James, MARCUCCI, Guido, BO YU, SANTHANAM, Ramasamy, HONGYAN WANG, HOELLERBAUER, Pia, MIMS, Alice, KLISOVIC, Rebecca, WALKER, Alison R, CHAN, Kenneth K

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How much? How frequent? How long? A clinical guide to new therapies in myelodysplastic syndromes von Blum, William

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TET2 Mutations Improve the New European LeukemiaNet Risk Classification of Acute Myeloid Leukemia: A Cancer and Leukemia Group B Study von METZELER, Klaus H, MAHARRY, Kati, WU, Yue-Zhong, BLUM, William, POWELL, Bayard L, CARTER, Thomas H, WETZLER, Meir, MOORE, Joseph O, KOLITZ, Jonathan E, BAER, Maria R, CARROLL, Andrew J, LARSON, Richard A, RADMACHER, Michael D, CALIGIURI, Michael A, MARCUCCI, Guido, BLOOMFIELD, Clara D, MROZEK, Krzysztof, MARGESON, Dean, BECKER, Heiko, CURFMAN, John, HOLLAND, Kelsi B, SCHWIND, Sebastian, WHITMAN, Susan P

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Lysine acetylation restricts mutant IDH2 activity to optimize transformation in AML cells von Chen, Dong, Xia, Siyuan, Zhang, Rukang, Li, Yuancheng, Famulare, Christopher A., Fan, Hao, Wu, Rong, Wang, Mei, Zhu, Allen C., Elf, Shannon E., Su, Rui, Dong, Lei, Arellano, Martha, Blum, William G., Mao, Hui, Lonial, Sagar, Stock, Wendy, Odenike, Olatoyosi, Le Beau, Michelle, Boggon, Titus J., He, Chuan, Chen, Jianjun, Gao, Xue, Levine, Ross L., Chen, Jing

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A phase I study of the fully human, fragment crystallizable-engineered, anti-CD-33 monoclonal antibody BI 836858 in patients with previously-treated acute myeloid leukemia von Vasu, Sumithira, Altman, Jessica K, Uy, Geoffrey L, Tallman, Martin S, Gojo, Ivana, Lozanski, Gerard, Burkard, Ute, Osswald, Annika, James, Pamela, Rüter, Björn, Blum, William

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RNA-dependent inhibition of ribonucleotide reductase is a major pathway for 5-azacytidine activity in acute myeloid leukemia von Aimiuwu, Josephine, Wang, Hongyan, Chen, Ping, Xie, Zhiliang, Wang, Jiang, Liu, Shujun, Klisovic, Rebecca, Mims, Alice, Blum, William, Marcucci, Guido, Chan, Kenneth K.

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Sex-associated differences in frequencies and prognostic impact of recurrent genetic alterations in adult acute myeloid leukemia (Alliance, AMLCG) von Ozga, Michael, Nicolet, Deedra, Mrózek, Krzysztof, Yilmaz, Ayse S., Kohlschmidt, Jessica, Larkin, Karilyn T., Blachly, James S., Oakes, Christopher C., Buss, Jill, Walker, Christopher J., Orwick, Shelley, Jurinovic, Vindi, Rothenberg-Thurley, Maja, Dufour, Annika, Schneider, Stephanie, Sauerland, Maria Cristina, Görlich, Dennis, Krug, Utz, Berdel, Wolfgang E., Woermann, Bernhard J., Hiddemann, Wolfgang, Braess, Jan, Subklewe, Marion, Spiekermann, Karsten, Carroll, Andrew J., Blum, William G., Powell, Bayard L., Kolitz, Jonathan E., Moore, Joseph O., Mayer, Robert J., Larson, Richard A., Uy, Geoffrey L., Stock, Wendy, Metzeler, Klaus H., Grimes, H. Leighton, Byrd, John C., Salomonis, Nathan, Herold, Tobias, Mims, Alice S., Eisfeld, Ann-Kathrin

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An open-label, phase I/II trial to determine the maximum tolerated dose and investigate safety, pharmacokinetics and efficacy of BI 836858, an unconjugated anti-CD33 monoclonal ant... von Fiedler, Walter, Montesinos, Pau, Schliemann, Christoph, Middeke, Jan, Vasu, Sumithira, Scholz, Christian W, Esteve, Jordi, Mondal, Shoubhik, Rüter, Björn, Burkard, Ute, Osswald, Annika, Blum, William

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The interleukin-3 receptor CD123 targeted SL-401 mediates potent cytotoxic activity against CD34 + CD123 + cells from acute myeloid leukemia/myelodysplastic syndrome patients and h... von Mani, Rajeswaran, Goswami, Swagata, Gopalakrishnan, Bhavani, Ramaswamy, Rahul, Wasmuth, Ronni, Tran, Minh, Mo, Xiaokui, Gordon, Amber, Bucci, Donna, Lucas, David M, Mims, Alice, Brooks, Christopher, Dorrance, Adrienne, Walker, Alison, Blum, William, Byrd, John C, Lozanski, Gerard, Vasu, Sumithira, Muthusamy, Natarajan

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RhoH is critical for cell-microenvironment interactions in chronic lymphocytic leukemia in mice and humans von Troeger, Anja, Johnson, Amy J., Wood, Jenna, Blum, William G., Andritsos, Leslie A., Byrd, John C., Williams, David A.

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