Amidino-Rocaglates: A Potent Class of eIF4A Inhibitors von Chu, Jennifer, Zhang, Wenhan, Cencic, Regina, Devine, William G., Beglov, Dmitri, Henkel, Thomas, Brown, Lauren E., Vajda, Sandor, Porco, John A., Pelletier, Jerry

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Rocaglates Induce Gain-of-Function Alterations to eIF4A and eIF4F von Chu, Jennifer, Zhang, Wenhan, Cencic, Regina, O’Connor, Patrick B.F., Robert, Francis, Devine, William G., Selznick, Asher, Henkel, Thomas, Merrick, William C., Brown, Lauren E., Baranov, Pavel V., Porco, John A., Pelletier, Jerry

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Global genetic analysis in mice unveils central role for cilia in congenital heart disease von Li, You, Klena, Nikolai T., Gabriel, George C., Liu, Xiaoqin, Kim, Andrew J., Lemke, Kristi, Chen, Yu, Chatterjee, Bishwanath, Devine, William, Damerla, Rama Rao, Chang, Chienfu, Yagi, Hisato, San Agustin, Jovenal T., Thahir, Mohamed, Anderton, Shane, Lawhead, Caroline, Vescovi, Anita, Pratt, Herbert, Morgan, Judy, Haynes, Leslie, Smith, Cynthia L., Eppig, Janan T., Reinholdt, Laura, Francis, Richard, Leatherbury, Linda, Ganapathiraju, Madhavi K., Tobita, Kimimasa, Pazour, Gregory J., Lo, Cecilia W.

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KCTD1/KCTD15 complexes control ectodermal and neural crest cell functions, and their impairment causes aplasia cutis von Raymundo, Jackelyn R, Zhang, Hui, Smaldone, Giovanni, Zhu, Wenjuan, Daly, Kathleen E, Glennon, Benjamin J, Pecoraro, Giovanni, Salvatore, Marco, Devine, William A, Lo, Cecilia W, Vitagliano, Luigi, Marneros, Alexander G

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Targeting translation initiation by synthetic rocaglates for treating MYC-driven lymphomas von Zhang, Xuan, Bi, Chengfeng, Lu, Ting, Zhang, Weiwei, Yue, Ting, Wang, Cheng, Tian, Tian, Zhang, Xiaoyan, Huang, Yuhua, Lunning, Matthew, Hao, Xinbao, Brown, Lauren E., Devine, William G., Vose, Julie, Porco, John A., Fu, Kai

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Profiling development of abdominal organs in the pig von Gabriel, George C., Devine, William A., Redel, Bethany K., Whitworth, Kristin M., Samuel, Melissa, Spate, Lee D., Cecil, Raissa F., Prather, Randall S., Wu, Yijen L., Wells, Kevin D., Lo, Cecilia W.

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Genetic link between renal birth defects and congenital heart disease von San Agustin, Jovenal T., Klena, Nikolai, Granath, Kristi, Panigrahy, Ashok, Stewart, Eileen, Devine, William, Strittmatter, Lara, Jonassen, Julie A., Liu, Xiaoqin, Lo, Cecilia W., Pazour, Gregory J.

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Inhibition of the Translation Initiation Factor eIF4A Enhances Tumor Cell Radiosensitivity von Lehman, Stacey L, Wechsler, Theresa, Schwartz, Kayla, Brown, Lauren E, Porco, John A, Devine, William G, Pelletier, Jerry, Shankavaram, Uma T, Camphausen, Kevin, Tofilon, Philip J

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Congenital heart disease and the specification of left-right asymmetry von Francis, Richard J B, Christopher, Adam, Devine, William A, Ostrowski, Lawrence, Lo, Cecilia

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Inhibition of translation initiation factor eIF4a inactivates heat shock factor 1 (HSF1) and exerts anti-leukemia activity in AML von Nishida, Yuki, Zhao, Ran, Heese, Lauren E., Akiyama, Hiroki, Patel, Shreya, Jaeger, Alex M., Jacamo, Rodrigo O., Kojima, Kensuke, Ma, Man Chun John, Ruvolo, Vivian R., Chachad, Dhruv, Devine, William, Lindquist, Susan, Davis, R. Eric, Porco, John A., Whitesell, Luke, Andreeff, Michael, Ishizawa, Jo

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IFT74 variants cause skeletal ciliopathy and motile cilia defects in mice and humans von Bakey, Zeineb, Cabrera, Oscar A, Hoefele, Julia, Antony, Dinu, Wu, Kaman, Stuck, Michael W, Micha, Dimitra, Eguether, Thibaut, Smith, Abigail O, van der Wel, Nicole N, Wagner, Matias, Strittmatter, Lara, Beales, Philip L, Jonassen, Julie A, Thiffault, Isabelle, Cadieux-Dion, Maxime, Boyes, Laura, Sharif, Saba, Tüysüz, Beyhan, Dunstheimer, Desiree, Niessen, Hans W M, Devine, William, Lo, Cecilia W, Mitchison, Hannah M, Schmidts, Miriam, Pazour, Gregory J

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Airway ciliary dysfunction and respiratory symptoms in patients with transposition of the great arteries von Zahid, Maliha, Bais, Abha, Tian, Xin, Devine, William, Lee, Dong Ming, Yau, Cyrus, Sonnenberg, Daniel, Beerman, Lee, Khalifa, Omar, Lo, Cecilia W

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Oxo-aglaiastatin-Mediated Inhibition of Translation Initiation von Itoua Maïga, Rayelle, Cencic, Regina, Chu, Jennifer, Waller, Daniel D., Brown, Lauren E., Devine, William G., Zhang, Wenhan, Sebag, Michael, Porco Jr, John A., Pelletier, Jerry

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Double outlet right ventricle von Bell-Cheddar, Yolandee, Devine, William A., Diaz-Castrillon, Carlos-Eduardo, Seese, Laura, Castro-Medina, Mario, Morales, Raymond, Follansbee, Christopher W., Alsaied, Tarek, Lin, Jiuann-Huey I.

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Fine-tuning of macrophage activation using synthetic rocaglate derivatives von Bhattacharya, Bidisha, Chatterjee, Sujoy, Devine, William G., Kobzik, Lester, Beeler, Aaron B., Porco, John A., Kramnik, Igor

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Exploring the Scope for Scale-Up of Organic Chemistry Using a Large Batch Microwave Reactor von Schmink, Jason R, Kormos, Chad M, Devine, William G, Leadbeater, Nicholas E

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Probing the energy efficiency of microwave heating and continuous-flow conventional heating as tools for organic chemistry von Leadbeater, Nicholas E., Devine, William G

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Brain Dysplasia Associated with Ciliary Dysfunction in Infants with Congenital Heart Disease von Panigrahy, Ashok, MD, Lee, Vincent, BS, Ceschin, Rafael, MS, Zuccoli, Giulio, MD, Beluk, Nancy, BS, Khalifa, Omar, BS, Votava-Smith, Jodie K., MD, DeBrunner, Mark, MD, Munoz, Ricardo, MD, Domnina, Yuliya, MD, Morell, Victor, MD, Wearden, Peter, MD, Sanchez De Toledo, Joan, MD, Devine, William, BS, Zahid, Maliha, MD, Lo, Cecilia W., PhD

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Microcomputed tomography provides high accuracy congenital heart disease diagnosis in neonatal and fetal mice von Kim, Andrew J, Francis, Richard, Liu, Xiaoqin, Devine, William A, Ramirez, Ricardo, Anderton, Shane J, Wong, Li Yin, Faruque, Fahim, Gabriel, George C, Chung, Wendy, Leatherbury, Linda, Tobita, Kimimasa, Lo, Cecilia W

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Identification and characterization of hundreds of potent and selective inhibitors of Trypanosoma brucei growth from a kinase-targeted library screening campaign von Diaz, Rosario, Luengo-Arratta, Sandra A, Seixas, João D, Amata, Emanuele, Devine, William, Cordon-Obras, Carlos, Rojas-Barros, Domingo I, Jimenez, Elena, Ortega, Fatima, Crouch, Sabrinia, Colmenarejo, Gonzalo, Fiandor, Jose Maria, Martin, Jose Julio, Berlanga, Manuela, Gonzalez, Silvia, Manzano, Pilar, Navarro, Miguel, Pollastri, Michael P

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