Novel TLR2-binding adjuvant induces enhanced T cell responses and tumor eradication von Zom, Gijs G, Willems, Marian M J H P, Khan, Selina, van der Sluis, Tetje C, Kleinovink, Jan Willem, Camps, Marcel G M, van der Marel, Gijsbert A, Filippov, Dmitri V, Melief, Cornelis J M, Ossendorp, Ferry

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An Enantioselective Organocatalytic Approach to Both Enantiomers of Lasubine II von Verkade, Jorge M. M, van der Pijl, Ferdi, Willems, Marian M. J. H. P, Quaedflieg, Peter J. L. M, van Delft, Floris L, Rutjes, Floris P. J. T

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Dual Synthetic Peptide Conjugate Vaccine Simultaneously Triggers TLR2 and NOD2 and Activates Human Dendritic Cells von Zom, Gijs G, Willems, Marian M. J. H. P, Meeuwenoord, Nico J, Reintjens, Niels R. M, Tondini, Elena, Khan, Selina, Overkleeft, Herman S, van der Marel, Gijsbert A, Codee, Jeroen D. C, Ossendorp, Ferry, Filippov, Dmitri V

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N‑Tetradecylcarbamyl Lipopeptides as Novel Agonists for Toll-like Receptor 2 von Willems, Marian M. J. H. P, Zom, Gijs G, Khan, Selina, Meeuwenoord, Nico, Melief, Cornelis J. M, van der Stelt, Mario, Overkleeft, Herman S, Codée, Jeroen D. C, van der Marel, Gijsbert A, Ossendorp, Ferry, Filippov, Dmitri V

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Lipophilic Muramyl Dipeptide-Antigen Conjugates as Immunostimulating Agents von Willems, Marian M. J. H. P., Zom, Gijs G., Meeuwenoord, Nico, Khan, Selina, Ossendorp, Ferry, Overkleeft, Herman S., van der Marel, Gijsbert A., Filippov, Dmitri V., Codée, Jeroen D. C.

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Design, automated synthesis and immunological evaluation of NOD2-ligand-antigen conjugates von Willems, Marian M J H P, Zom, Gijs G, Meeuwenoord, Nico, Ossendorp, Ferry A, Overkleeft, Herman S, van der Marel, Gijsbert A, Codée, Jeroen D C, Filippov, Dmitri V

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Metabolomics Profile in Depression: A Pooled Analysis of 230 Metabolic Markers in 5283 Cases With Depression and 10,145 Controls von Bot, Mariska, Milaneschi, Yuri, Al-Shehri, Tahani, Amin, Najaf, Garmaeva, Sanzhima, Onderwater, Gerrit L.J., Pool, Rene, Thesing, Carisha S., Vijfhuizen, Lisanne S., Vogelzangs, Nicole, Arts, Ilja C.W., Demirkan, Ayse, van Duijn, Cornelia, van Greevenbroek, Marleen, van der Kallen, Carla J.H., Köhler, Sebastian, Ligthart, Lannie, van den Maagdenberg, Arn M.J.M., Mook-Kanamori, Dennis O., de Mutsert, Renée, Tiemeier, Henning, Schram, Miranda T., Stehouwer, Coen D.A., Terwindt, Gisela M., Willems van Dijk, Ko, Fu, Jingyuan, Zhernakova, Alexandra, Beekman, Marian, Slagboom, P. Eline, Boomsma, Dorret I., Penninx, Brenda W.J.H., Beekman, M., Suchiman, H.E.D., Deelen, J., Amin, N., Beulens, J.W., van der Bom, J.A., Bomer, N., Demirkan, A., van Hilten, J.A., Meessen, J.M.T.A., Pool, R., Moed, M.H., Fu, J., Onderwater, G.L.J., Rutters, F., So-Osman, C., van der Flier, W.M., van der Heijden, A.A.W.A., van der Spek, A., Asselbergs, F.W., Boersma, E., Elders, P.M., Geleijnse, J.M., Ikram, M.A., Kloppenburg, M., Meulenbelt, I., Mooijaart, S.P., Nelissen, R.G.H.H., Netea, M.G., Penninx, B.W.J.H., Stehouwer, C.D.A., Teunissen, C.E., Terwindt, G.M., ’t Hart, L.M., van den Maagdenberg, A.M.J.M., van der Harst, P., van der Horst, I.C.C., van der Kallen, C.J.H., van Greevenbroek, M.M.J., van Spil, W.E., Wijmenga, C., Zwinderman, A.H., Zhernikova, A., Jukema, J.W., Sattar, N.

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Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA von Kettunen, Johannes, Demirkan, Ayşe, Würtz, Peter, Draisma, Harmen H.M., Haller, Toomas, Rawal, Rajesh, Vaarhorst, Anika, Kangas, Antti J., Lyytikäinen, Leo-Pekka, Pirinen, Matti, Pool, René, Sarin, Antti-Pekka, Soininen, Pasi, Tukiainen, Taru, Wang, Qin, Tiainen, Mika, Tynkkynen, Tuulia, Amin, Najaf, Zeller, Tanja, Beekman, Marian, Deelen, Joris, van Dijk, Ko Willems, Esko, Tõnu, Hottenga, Jouke-Jan, van Leeuwen, Elisabeth M, Lehtimäki, Terho, Mihailov, Evelin, Rose, Richard J., de Craen, Anton J.M., Gieger, Christian, Kähönen, Mika, Perola, Markus, Blankenberg, Stefan, Savolainen, Markku J., Verhoeven, Aswin, Viikari, Jorma, Willemsen, Gonneke, Boomsma, Dorret I., van Duijn, Cornelia M., Eriksson, Johan, Jula, Antti, Järvelin, Marjo-Riitta, Kaprio, Jaakko, Metspalu, Andres, Raitakari, Olli, Salomaa, Veikko, Slagboom, P. Eline, Waldenberger, Melanie, Ripatti, Samuli, Ala-Korpela, Mika

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Genome-wide association study identifies novel genetic variants contributing to variation in blood metabolite levels von Draisma, Harmen H. M., Pool, René, Kobl, Michael, Jansen, Rick, Petersen, Ann-Kristin, Vaarhorst, Anika A. M., Yet, Idil, Haller, Toomas, Demirkan, Ayşe, Esko, Tõnu, Zhu, Gu, Böhringer, Stefan, Beekman, Marian, van Klinken, Jan Bert, Römisch-Margl, Werner, Prehn, Cornelia, Adamski, Jerzy, de Craen, Anton J. M., van Leeuwen, Elisabeth M., Amin, Najaf, Dharuri, Harish, Westra, Harm-Jan, Franke, Lude, de Geus, Eco J. C., Hottenga, Jouke Jan, Willemsen, Gonneke, Henders, Anjali K., Montgomery, Grant W., Nyholt, Dale R., Whitfield, John B., Penninx, Brenda W., Spector, Tim D., Metspalu, Andres, Eline Slagboom, P., van Dijk, Ko Willems, ‘t Hoen, Peter A. C., Strauch, Konstantin, Martin, Nicholas G., van Ommen, Gert-Jan B., Illig, Thomas, Bell, Jordana T., Mangino, Massimo, Suhre, Karsten, McCarthy, Mark I., Gieger, Christian, Isaacs, Aaron, van Duijn, Cornelia M., Boomsma, Dorret I.

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Integration of epidemiologic, pharmacologic, genetic and gut microbiome data in a drug–metabolite atlas von Liu, Jun, Lahousse, Lies, Nivard, Michel G., Bot, Mariska, Chen, Lianmin, van Klinken, Jan Bert, Thesing, Carisha S., Beekman, Marian, van den Akker, Erik Ben, Slieker, Roderick C., Waterham, Eveline, van der Kallen, Carla J. H., de Boer, Irene, Li-Gao, Ruifang, Vojinovic, Dina, Amin, Najaf, Radjabzadeh, Djawad, Kraaij, Robert, Alferink, Louise J. M., Murad, Sarwa Darwish, Uitterlinden, André G., Willemsen, Gonneke, Pool, Rene, Milaneschi, Yuri, van Heemst, Diana, Suchiman, H. Eka D., Rutters, Femke, Elders, Petra J. M., Beulens, Joline W. J., van der Heijden, Amber A. W. A., van Greevenbroek, Marleen M. J., Arts, Ilja C. W., Onderwater, Gerrit L. J., van den Maagdenberg, Arn M. J. M., Mook-Kanamori, Dennis O., Hankemeier, Thomas, Terwindt, Gisela M., Stehouwer, Coen D. A., Geleijnse, Johanna M., ‘t Hart, Leen M., Slagboom, P. Eline, van Dijk, Ko Willems, Zhernakova, Alexandra, Fu, Jingyuan, Penninx, Brenda W. J. H., Boomsma, Dorret I., Demirkan, Ayşe, Stricker, Bruno H. C., van Duijn, Cornelia M.

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Author Correction: Heritability estimates for 361 blood metabolites across 40 genome-wide association studies von Hagenbeek, Fiona A., Pool, René, van Dongen, Jenny, Draisma, H. M., Jan Hottenga, Jouke, Willemsen, Gonneke, Abdellaoui, Abdel, Fedko, Iryna O., den Braber, Anouk, Visser, Pieter Jelle, de Geus, Eco J. C. N., Willems van Dijk, Ko, Verhoeven, Aswin, Suchiman, H. Eka, Beekman, Marian, Slagboom, P. Eline, van Duijn, Cornelia M., Harms, Amy C., Hankemeier, Thomas, Bartels, Meike, Nivard, Michel G., Boomsma, Dorret I.

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Investigating the relationships between unfavourable habitual sleep and metabolomic traits: evidence from multi-cohort multivariable regression and Mendelian randomization analyses von Bos, Maxime M, Goulding, Neil J, Lee, Matthew A, Hofman, Amy, Bot, Mariska, Pool, René, Vijfhuizen, Lisanne S, Zhang, Xiang, Li, Chihua, Mustafa, Rima, Neville, Matt J, Li-Gao, Ruifang, Trompet, Stella, Beekman, Marian, Biermasz, Nienke R, Boomsma, Dorret I, de Boer, Irene, Christodoulides, Constantinos, Dehghan, Abbas, van Dijk, Ko Willems, Ford, Ian, Ghanbari, Mohsen, Heijmans, Bastiaan T, Ikram, M Arfan, Jukema, J Wouter, Mook-Kanamori, Dennis O, Karpe, Fredrik, Luik, Annemarie I, Lumey, L H, van den Maagdenberg, Arn M J M, Mooijaart, Simon P, de Mutsert, Renée, Penninx, Brenda W J H, Rensen, Patrick C N, Richmond, Rebecca C, Rosendaal, Frits R, Sattar, Naveed, Schoevers, Robert A, Slagboom, P Eline, Terwindt, Gisela M, Thesing, Carisha S, Wade, Kaitlin H, Wijsman, Carolien A, Willemsen, Gonneke, Zwinderman, Aeilko H, van Heemst, Diana, Noordam, Raymond, Lawlor, Deborah A

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Blood Metabolomic Measures Associate With Present and Future Glycemic Control in Type 2 Diabetes von ‘t Hart, Leen M, Vogelzangs, Nicole, Mook-Kanamori, Dennis O, Brahimaj, Adela, Nano, Jana, van der Heijden, Amber A W A, Willems van Dijk, Ko, Slieker, Roderick C, Steyerberg, Ewout W, Ikram, M Arfan, Beekman, Marian, Boomsma, Dorret I, van Duijn, Cornelia M, Slagboom, P Eline, Stehouwer, Coen D A, Schalkwijk, Casper G, Arts, Ilja C W, Dekker, Jacqueline M, Dehghan, Abbas, Muka, Taulant, van der Kallen, Carla J H, Nijpels, Giel, van Greevenbroek, Marleen M J

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Variants near TERT and TERC influencing telomere length are associated with high-grade glioma risk von Walsh, Kyle M, Codd, Veryan, Smirnov, Ivan V, Rice, Terri, Decker, Paul A, Hansen, Helen M, Kollmeyer, Thomas, Kosel, Matthew L, Molinaro, Annette M, McCoy, Lucie S, Bracci, Paige M, Cabriga, Belinda S, Pekmezci, Melike, Zheng, Shichun, Wiemels, Joseph L, Pico, Alexander R, Tihan, Tarik, Berger, Mitchell S, Chang, Susan M, Prados, Michael D, Lachance, Daniel H, O'Neill, Brian Patrick, Sicotte, Hugues, Eckel-Passow, Jeanette E, van der Harst, Pim, Wiencke, John K, Samani, Nilesh J, Jenkins, Robert B, Wrensch, Margaret R

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Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls von Clayton, David G, Cardon, Lon R, Duncanson, Audrey, Ouwehand, Willem H, Todd, John A, Donnelly, Peter, Easton, Doug, Evans, David, Morris, Andrew P, Spencer, Chris C. A, Boorman, James P, Cant, Barbara, Everson, Ursula, Hussey, Judith M, Knight, Alexandra S, Nutland, Sarah, Stevens, Helen E, Watkins, Nicholas A, Jones, Richard W, Ring, Susan M, Breen, Gerome, Caesar, Sian, Green, Elaine K, Grozeva, Detelina, Jones, Ian R, Kirov, George, Moskvina, Valentina, Nikolov, Ivan, Collier, David A, Farmer, Anne, Williamson, Richard, Young, Allan H, Ball, Stephen G, Balmforth, Anthony J, Bishop, D. Timothy, Iles, Mark M, Dixon, Richard J, Stevens, Suzanne, Thompson, John R, Bredin, Francesca, Tremelling, Mark, Drummond, Hazel, Nimmo, Elaine R, Fisher, Sheila A, Forbes, Alastair, Lewis, Cathryn M, Prescott, Natalie J, Barbour, Jamie, Mohiuddin, M. Khalid, Mansfield, John C, Cummings, Fraser R, Connell, John, Dobson, Richard, Gungadoo, Johannie, Newhouse, Stephen J, Barton, Anne, Bruce, Ian N, John, Sally L, Potter, Catherine, Silman, Alan J, Symmons, Deborah P. M, Dunger, David B, Widmer, Barry, Frayling, Timothy M, Lango, Hana, Perry, John R. B, Groves, Christopher J, Rayner, Nigel W, Timpson, Nicholas J, Zeggini, Eleftheria, Newport, Melanie, Vannberg, Fredrik, Farrar, Claire, Wordsworth, Paul, Brown, Matthew A, Franklyn, Jayne A, Heward, Joanne M, Simmonds, Matthew J, Seal, Sheila, Stratton, Michael R, Ban, Maria, Conway, David, Chaney, Amy, Ghori, Mohammed J. R, Gwilliam, Rhian, Hunt, Sarah E, McGinnis, Ralph, Potter, Simon, Whittaker, Pamela, Widden, Claire, Withers, David, Hallgrimsdottir, Ingileif B, Vukcevic, Damjan, Bentley, David, Caulfield, Mark, Compston, Alistair, Farrall, Martin, Hall, Alistair S, Hattersley, Andrew T, Mathew, Christopher G

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Genetics and Not Shared Environment Explains Familial Resemblance in Adult Metabolomics Data von Pool, René, Hagenbeek, Fiona A., Hendriks, Anne M., van Dongen, Jenny, Willemsen, Gonneke, de Geus, Eco, Willems van Dijk, Ko, Verhoeven, Aswin, Suchiman, H. Eka, Beekman, Marian, Slagboom, P. Eline, Harms, Amy C., Hankemeier, Thomas, Boomsma, Dorret I.

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Higher thyrotropin leads to unfavorable lipid profile and somewhat higher cardiovascular disease risk: evidence from multi-cohort Mendelian randomization and metabolomic profiling von van Vliet, Nicolien A, Bos, Maxime M, Thesing, Carisha S, Chaker, Layal, Pietzner, Maik, Houtman, Evelyn, Neville, Matt J, Li-Gao, Ruifang, Trompet, Stella, Mustafa, Rima, Ahmadizar, Fariba, Beekman, Marian, Bot, Mariska, Budde, Kathrin, Christodoulides, Constantinos, Dehghan, Abbas, Delles, Christian, Elliott, Paul, Evangelou, Marina, Gao, He, Ghanbari, Mohsen, van Herwaarden, Antonius E, Ikram, M Arfan, Jaeger, Martin, Jukema, J Wouter, Karaman, Ibrahim, Karpe, Fredrik, Kloppenburg, Margreet, Meessen, Jennifer M T A, Meulenbelt, Ingrid, Milaneschi, Yuri, Mooijaart, Simon P, Mook-Kanamori, Dennis O, Netea, Mihai G, Netea-Maier, Romana T, Peeters, Robin P, Penninx, Brenda W J H, Sattar, Naveed, Slagboom, P Eline, Suchiman, H Eka D, Völzke, Henry, Willems van Dijk, Ko, Noordam, Raymond, van Heemst, Diana

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The sutureless aortic valve at 1 year: A large multicenter cohort study von Fischlein, Theodor, MD, PhD, Meuris, Bart, MD, PhD, Hakim-Meibodi, Kavous, MD, Misfeld, Martin, MD, PhD, Carrel, Thierry, MD, PhD, Zembala, Marian, MD, PhD, Gaggianesi, Sara, DVM, Madonna, Francesco, MD, Laborde, François, MD, Asch, Federico, MD, Haverich, Axel, MD, PhD

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Clinical and haemodynamic outcomes in 658 patients receiving the Perceval sutureless aortic valve: early results from a prospective European multicentre study (the Cavalier Trial) von Laborde, François, Fischlein, Theodor, Hakim-Meibodi, Kavous, Misfeld, Martin, Carrel, Thierry, Zembala, Marian, Madonna, Francesco, Meuris, Bart, Haverich, Axel, Shrestha, Malakh

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Toxic iron species in lower-risk myelodysplastic syndrome patients: course of disease and effects on outcome von Hoeks, Marlijn, Bagguley, Tim, van Marrewijk, Corine, Smith, Alex, Bowen, David, Culligan, Dominic, Kolade, Seye, Symeonidis, Argiris, Garelius, Hege, Spanoudakis, Michail, Langemeijer, Saskia, Roelofs, Rian, Wiegerinck, Erwin, Tatic, Aurelia, Killick, Sally, Panagiotidis, Panagiotis, Stanca, Oana, Hellström-Lindberg, Eva, Cermak, Jaroslav, van der Klauw, Melanie, Wouters, Hanneke, van Kraaij, Marian, Blijlevens, Nicole, Swinkels, Dorine W., de Witte, Theo

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