Monoacidic Inhibitors of the Kelch-like ECH-Associated Protein 1: Nuclear Factor Erythroid 2‑Related Factor 2 (KEAP1:NRF2) Protein–Protein Interaction with High Cell Potency Identi... von Davies, Thomas G, Wixted, William E, Coyle, Joseph E, Griffiths-Jones, Charlotte, Hearn, Keisha, McMenamin, Rachel, Norton, David, Rich, Sharna J, Richardson, Caroline, Saxty, Gordon, Willems, Henriëtte M. G, Woolford, Alison J.-A, Cottom, Joshua E, Kou, Jen-Pyng, Yonchuk, John G, Feldser, Heidi G, Sanchez, Yolanda, Foley, Joseph P, Bolognese, Brian J, Logan, Gregory, Podolin, Patricia L, Yan, Hongxing, Callahan, James F, Heightman, Tom D, Kerns, Jeffrey K

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Interactions between mitochondrial reactive oxygen species and cellular glucose metabolism von Liemburg-Apers, Dania C., Willems, Peter H. G. M., Koopman, Werner J. H., Grefte, Sander

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Fragment-Guided Discovery of Pyrazole Carboxylic Acid Inhibitors of the Kelch-like ECH-Associated Protein 1: Nuclear Factor Erythroid 2 Related Factor 2 (KEAP1:NRF2) Protein−Protei... von Norton, David, Bonnette, William G, Callahan, James F, Carr, Maria G, Griffiths-Jones, Charlotte M, Heightman, Tom D, Kerns, Jeffrey K, Nie, Hong, Rich, Sharna J, Richardson, Caroline, Rumsey, William, Sanchez, Yolanda, Verdonk, Marcel L, Willems, Henriëtte M. G, Wixted, William E, Woolford, Alison J.-A, Wu, Zining, Davies, Thomas G

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The Identification of Potent, Selective, and Brain Penetrant PI5P4Kγ Inhibitors as In Vivo-Ready Tool Molecules von Rooney, Timothy P. C., Aldred, Gregory G., Boffey, Helen K., Willems, Henriëtte M. G., Edwards, Simon, Chawner, Stephen J., Scott, Duncan E., Green, Christopher, Winpenny, David, Skidmore, John, Clarke, Jonathan H., Andrews, Stephen P.

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Systematic Investigation of the Permeability of Androgen Receptor PROTACs von Scott, Duncan E, Rooney, Timothy P. C, Bayle, Elliott D, Mirza, Tashfina, Willems, Henriette M. G, Clarke, Jonathan H, Andrews, Stephen P, Skidmore, John

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Rescue from galactose-induced death of Leigh Syndrome patient cells by pyruvate and NAD von Iannetti, Eligio F., Smeitink, Jan A. M., Willems, Peter H. G. M., Beyrath, Julien, Koopman, Werner J. H.

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Mitochondrial function and morphology are impaired in parkin-mutant fibroblasts von Mortiboys, Heather, Thomas, Kelly Jean, Koopman, Werner J. H., Klaffke, Stefanie, Abou-Sleiman, Patrick, Olpin, Simon, Wood, Nicholas W., Willems, Peter H. G. M., Smeitink, Jan A. M., Cookson, Mark R., Bandmann, Oliver

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Identification of ARUK2002821 as an isoform-selective PI5P4Kα inhibitor von Willems, Henriëtte M. G, Edwards, Simon, Boffey, Helen K, Chawner, Stephen J, Green, Christopher, Romero, Tamara, Winpenny, David, Skidmore, John, Clarke, Jonathan H, Andrews, Stephen P

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Pulmonary vascular changes in extremely preterm sheep after intra-amniotic exposure to Ureaplasma parvum and lipopolysaccharide von Willems, Monique G M, Kemp, Matthew W, Fast, Laura A, Wagemaker, Nick M M, Janssen, Leon E W, Newnham, John P, Payne, Matt S, Spiller, Owen B, Kallapur, Suhas G, Jobe, Alan H, Delhaas, Tammo, Kramer, Boris W, Wolfs, Tim G A M

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Automated quantification and integrative analysis of 2D and 3D mitochondrial shape and network properties von Nikolaisen, Julie, Nilsson, Linn I H, Pettersen, Ina K N, Willems, Peter H G M, Lorens, James B, Koopman, Werner J H, Tronstad, Karl J

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Small-Molecule Inhibitors of the MDM2-p53 Protein−Protein Interaction Based on an Isoindolinone Scaffold von Hardcastle, Ian R, Ahmed, Shafiq U, Atkins, Helen, Farnie, Gillian, Golding, Bernard T, Griffin, Roger J, Guyenne, Sabrina, Hutton, Claire, Källblad, Per, Kemp, Stuart J, Kitching, Martin S, Newell, David R, Norbedo, Stefano, Northen, Julian S, Reid, Rebecca J, Saravanan, K, Willems, Henriëtte M. G, Lunec, John

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Modulation of oxidative phosphorylation and redox homeostasis in mitochondrial NDUFS4 deficiency via mesenchymal stem cells von Melcher, Marlen, Danhauser, Katharina, Seibt, Annette, Degistirici, Özer, Baertling, Fabian, Kondadi, Arun Kumar, Reichert, Andreas S, Koopman, Werner J H, Willems, Peter H G M, Rodenburg, Richard J, Mayatepek, Ertan, Meisel, Roland, Distelmaier, Felix

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Broad defects in the energy metabolism of leukocytes underlie immunoparalysis in sepsis von Cheng, Shih-Chin, Scicluna, Brendon P, Arts, Rob J W, Gresnigt, Mark S, Lachmandas, Ekta, Giamarellos-Bourboulis, Evangelos J, Kox, Matthijs, Manjeri, Ganesh R, Wagenaars, Jori A L, Cremer, Olaf L, Leentjens, Jenneke, van der Meer, Anne J, van de Veerdonk, Frank L, Bonten, Marc J, Schultz, Marcus J, Willems, Peter H G M, Pickkers, Peter, Joosten, Leo A B, van der Poll, Tom, Netea, Mihai G

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Functional Analysis of Picornavirus 2B Proteins: Effects on Calcium Homeostasis and Intracellular Protein Trafficking von DE JONG, Arjan S, DE MATTIA, Fabrizio, VAN DOMMELEN, Michiel M, LANKE, Kjerstin, MELCHERS, Willem J. G, WILLEMS, Peter H. G. M, VAN KUPPEVELD, Frank J. M

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The antioxidant Trolox restores mitochondrial membrane potential and Ca2+-stimulated ATP production in human complex I deficiency von Distelmaier, Felix, Visch, Henk-Jan, Smeitink, Jan A. M., Mayatepek, Ertan, Koopman, Werner J. H., Willems, Peter H. G. M.

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Controlling T‑Cell Activation with Synthetic Dendritic Cells Using the Multivalency Effect von Hammink, Roel, Mandal, Subhra, Eggermont, Loek J, Nooteboom, Marco, Willems, Peter H. G. M, Tel, Jurjen, Rowan, Alan E, Figdor, Carl G, Blank, Kerstin G

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Multiplexed high-content analysis of mitochondrial morphofunction using live-cell microscopy von Iannetti, Eligio F, Smeitink, Jan A M, Beyrath, Julien, Willems, Peter H G M, Koopman, Werner J H

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Monogenic Mitochondrial Disorders von Koopman, Werner J.H, Willems, Peter H.G.M, Smeitink, Jan A.M

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Human NADH:ubiquinone oxidoreductase deficiency: radical changes in mitochondrial morphology? von Koopman, Werner J. H, Verkaart, Sjoerd, Visch, Henk Jan, van Emst-de Vries, Sjenet, Nijtmans, Leo G. J, Smeitink, Jan A. M, Willems, Peter H. G. M

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