O.1.2-1 ACTIVE-AGE@home: a home-based functional exercise program for community dwelling frail older adults: mixed method study von Vrancken, Dimitri, Tambeur, Jade, De Keyser, Emma, De Smedt, Elke, Belpaire, Marianne, De Cauwer, Sara, Willems, Kathleen, De Clerck, Ine, Beckwée, David, Peersman, Wim, Van de Velde, Dominique, Lieten, Siddhartha, Annemans, Lieven, De Vriendt, Patricia

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Mobilization of hematopoietic progenitor cells in patients with liver cirrhosis von Gehling, Ursula M, Willems, Marc, Schlagner, Kathleen, Benndorf, Ralf A, Dandri, Maura, Petersen, Jörg, Sterneck, Martina, Pollok, Joerg-Matthias, Hossfeld, Dieter K, Rogiers, Xavier

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Extensive Genomic Diversity among Bovine-Adapted Staphylococcus aureus: Evidence for a Genomic Rearrangement within CC97 von Budd, Kathleen E, McCoy, Finola, Monecke, Stefan, Cormican, Paul, Mitchell, Jennifer, Keane, Orla M

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Final Analysis of Efficacy and Safety of Single-Dose Ad26.COV2.S von Sadoff, Jerald, Gray, Glenda, Vandebosch, An, Cárdenas, Vicky, Shukarev, Georgi, Grinsztejn, Beatriz, Goepfert, Paul A, Truyers, Carla, Van Dromme, Ilse, Spiessens, Bart, Vingerhoets, Johan, Custers, Jerome, Scheper, Gert, Robb, Merlin L, Treanor, John, Ryser, Martin F, Barouch, Dan H, Swann, Edith, Marovich, Mary A, Neuzil, Kathleen M, Corey, Lawrence, Stoddard, Jeffrey, Hardt, Karin, Ruiz-Guiñazú, Javier, Le Gars, Mathieu, Schuitemaker, Hanneke, Van Hoof, Johan, Struyf, Frank, Douoguih, Macaya

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Age-related immune response heterogeneity to SARS-CoV-2 vaccine BNT162b2 von Collier, Dami A., Ferreira, Isabella A. T. M., Kotagiri, Prasanti, Datir, Rawlings P., Lim, Eleanor Y., Touizer, Emma, Meng, Bo, Abdullahi, Adam, Elmer, Anne, Kingston, Nathalie, Graves, Barbara, Le Gresley, Emma, Caputo, Daniela, Bergamaschi, Laura, Smith, Kenneth G. C., Bradley, John R., Ceron-Gutierrez, Lourdes, Cortes-Acevedo, Paulina, Barcenas-Morales, Gabriela, Linterman, Michelle A., McCoy, Laura E., Davis, Chris, Thomson, Emma, Lyons, Paul A., McKinney, Eoin, Doffinger, Rainer, Wills, Mark, Gupta, Ravindra K.

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Recurrent heterozygous PAX6 missense variants cause severe bilateral microphthalmia via predictable effects on DNA–protein interaction von Williamson, Kathleen A., Hall, H. Nikki, Owen, Liusaidh J., Livesey, Benjamin J., Hanson, Isabel M., Adams, G., Bodek, Simon, Calvas, Patrick, Castle, Bruce, Clarke, Michael, Deng, Alexander T., Edery, Patrick, Fisher, Richard, Gillessen-Kaesbach, Gabriele, Heon, Elise, Hurst, Jane, Josifova, Dragana, Lorenz, Birgit, McKee, Shane, Meire, Francoise, Moore, Anthony T., Parker, Michael, Reiff, Charlotte M., Self, Jay, Tobias, Edward S., Verheij, Joke B., Willems, Marjolaine, Williams, Denise, van Heyningen, Veronica, Marsh, Joseph A., FitzPatrick, David R.

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Decreased prostate cancer-specific survival of men with BRCA2 mutations from multiple breast cancer families von Thorne, Heather, Willems, Amber J, Niedermayr, Eveline, Hoh, Ivan M Y, Li, Jason, Clouston, David, Mitchell, Gillian, Fox, Stephen, Hopper, John L, Bolton, Damien

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Assessing genetic diversity among Brettanomyces yeasts by DNA fingerprinting and whole-genome sequencing von Crauwels, Sam, Zhu, Bo, Steensels, Jan, Busschaert, Pieter, De Samblanx, Gorik, Marchal, Kathleen, Willems, Kris A, Verstrepen, Kevin J, Lievens, Bart

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Rare and low-frequency coding variants alter human adult height von Wood, Andrew R., Kjaer, Troels R., Lu, Yingchang, Thorleifsson, Gudmar, Turcot, Valérie, Young, Kristin L., Rivas, Manuel A., Abecasis, Goncalo, Aben, Katja K., Allin, Kristine H., Blüher, Matthias, Bots, Michiel L., Brilliant, Murray H., Carey, David J., Chambers, John C., Chasman, Daniel I., Chen, Yii-Der Ida, Chu, Audrey Y., Collins, Francis S., Cook, James P., de Groot, Mark C. H., de Mutsert, Renée, Ebeling, Tapani, Evangelou, Evangelos, Feng, Shuang, Ford, Ian, Fornage, Myriam, Gandin, Ilaria, Gordon, Scott D., Gustafsson, Stefan, Hattersley, Andrew T., Heid, Iris M., Helgeland, Øyvind, Hewitt, Alex W., Hovingh, G. Kees, Hoyng, Carel B., Huang, Paul L., Hveem, Kristian, Ikram, M. Arfan, Jansson, Jan-Håkan, Jarvik, Gail P., Jiang, Xuejuan, Jukema, J. Wouter, Kitajima, Hidetoshi, Kluivers, Kirsten B., Kontto, Jukka, Kooner, Jaspal S., Kriebel, Jennifer, Kuusisto, Johanna, Langenberg, Claudia, Lee, I-Te, Li, Huaixing, Lin, Honghuang, Lophatananon, Artitaya, Lyytikäinen, Leo-Pekka, Madden, Pamela A. F., Männistö, Satu, Mazul, Angela L., Metspalu, Andres, Mook-Kanamori, Dennis O., Morgan, Anna, Morris, Andrew P., Müller-Nurasyid, Martina, Nalls, Mike A., Nielsen, Sune F., Njølstad, Pål R., Palmer, Colin N. A., Pasterkamp, Gerard, Pedersen, Oluf, Perola, Markus, Perry, James A., Person, Thomas N., Salomaa, Veikko, Samani, Nilesh J., Sandow, Kevin, Schmidt, Marjanka K., Segura-Lepe, Marcelo P., Sim, Xueling, Small, Kerrin S., Southam, Lorraine, Steinthorsdottir, Valgerdur, Stumvoll, Michael, Tansey, Katherine E., Tardif, Jean-Claude, Taylor, Kent D., Thompson, Deborah J., Tyrer, Jonathan P., Uitterlinden, André G., van Schoor, Natasja M., Vozzi, Diego, Wang, Shuai, Wang, Yiqin, Wilson, James G., Young, Robin, Willer, Cristen J., Liu, Dajiang J., North, Kari E., Kutalik, Zoltán, Loos, Ruth J. F., Deloukas, Panos

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A wearable real-time particulate monitor demonstrates that soaking hay reduces dust exposure von Ivester, Kathleen M, Ni, Ji-Qin, Couetil, Laurent L, Peters, Thomas M, Tatum, Marcus, Willems, Lynn, Park, Jae Hong

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New insights into the clinical and molecular spectrum of the novel CYFIP2-related neurodevelopmental disorder and impairment of the WRC-mediated actin dynamics von Begemann, Anaïs, Sticht, Heinrich, Begtrup, Amber, Vitobello, Antonio, Faivre, Laurence, Banka, Siddharth, Alhaddad, Bader, Asadollahi, Reza, Becker, Jessica, Bierhals, Tatjana, Brown, Kathleen E., Bruel, Ange-Line, Brunet, Theresa, Carneiro, Maryline, Cremer, Kirsten, Day, Robert, Denommé-Pichon, Anne-Sophie, Dyment, Dave A., Engels, Hartmut, Fisher, Rachel, Goh, Elaine S., Hajianpour, M. J., Haertel, Lucia Ribeiro Machado, Hauer, Nadine, Hempel, Maja, Herget, Theresia, Johannsen, Jessika, Kraus, Cornelia, Le Guyader, Gwenaël, Lesca, Gaetan, Mau-Them, Frédéric Tran, McDermott, John Henry, McWalter, Kirsty, Meyer, Pierre, Õunap, Katrin, Popp, Bernt, Reimand, Tiia, Riedhammer, Korbinian M., Russo, Martina, Sadleir, Lynette G., Saenz, Margarita, Schiff, Manuel, Schuler, Elisabeth, Syrbe, Steffen, Van der Ven, Amelie Theresa, Verloes, Alain, Willems, Marjolaine, Zweier, Christiane, Steindl, Katharina, Zweier, Markus, Rauch, Anita

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Effect of a Pediatric Early Warning System on All-Cause Mortality in Hospitalized Pediatric Patients: The EPOCH Randomized Clinical Trial von Parshuram, Christopher S, Dryden-Palmer, Karen, Farrell, Catherine, Gottesman, Ronald, Gray, Martin, Hutchison, James S, Helfaer, Mark, Hunt, Elizabeth A, Joffe, Ari R, Lacroix, Jacques, Moga, Michael Alice, Nadkarni, Vinay, Ninis, Nelly, Parkin, Patricia C, Wensley, David, Willan, Andrew R, Tomlinson, George A

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Acute Normal Tissue Reactions in Head-and-Neck Cancer Patients Treated With IMRT: Influence of Dose and Association With Genetic Polymorphisms in DNA DSB Repair Genes von Werbrouck, Joke, M.Sc, De Ruyck, Kim, Ph.D, Duprez, Fréderic, M.D, Veldeman, Liv, M.D, Claes, Kathleen, Ph.D, Van Eijkeren, Marc, M.D., Ph.D, Boterberg, Tom, M.D., Ph.D, Willems, Petra, M.Sc, Vral, Anne, Ph.D, De Neve, Wilfried, M.D., Ph.D, Thierens, Hubert, Ph.D

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A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance von Hivert, Marie-France, Scott, Robert A, Grimsby, Jonna L, Chen, Han, Amin, Najaf, Barnes, Daniel, Cadby, Gemma, Hottenga, Jouke-Jan, Ingelsson, Erik, Kanoni, Stavroula, Ladenvall, Claes, Lagou, Vasiliki, Liu, Yongmei, Martinez-Larrad, Maria Teresa, Navarro, Pau, Strawbridge, Rona J, Tanaka, Toshiko, de Andrade, Mariza, Aulchenko, Yurii, Balkau, Beverley, Beilby, John P, Blangero, John, Boban, Mladen, Boomsma, Dorret I, Böttcher, Yvonne, Bouchard, Claude, Budimir, Danijela, Clarke, Robert, Corbatón-Anchuelo, Arturo, Couper, David, Dedoussis, George V, Erdos, Michael R, Eriksson, Johan G, Franzosi, Maria Grazia, Franks, Paul W, Galan, Pilar, de Geus, Eco, Hallmans, Göran, Hansson, Ola, Harris, Tamara B, Hayward, Caroline, Hingorani, Aroon, Johnson, Paul C D, Jukema, J Wouter, Jula, Antti, Kolcic, Ivana, Kumari, Meena, Lakka, Timo, Lannfelt, Lars, Lathrop, G Mark, Lind, Lars, Lobbens, Stéphane, Loos, Ruth J F, Lyssenko, Valeriya, Magnusson, Patrik K E, Marmot, Michael, Meneton, Pierre, Mooser, Vincent, Morken, Mario A, Ong, Ken K, Oostra, Ben A, Palmer, Lyle J, Palotie, Aarno, Peden, John F, Pedersen, Nancy L, Penninx, Brenda, Perola, Markus, Peyser, Patricia A, Räikkönen, Katri, Rehnberg, Emil, Rotter, Jerome I, Rudan, Igor, Ruokonen, Aimo, Saaristo, Timo, Sabater-Lleal, Maria, Salomaa, Veikko, Saxena, Richa, Sennblad, Bengt, Shuldiner, Alan R, Sijbrands, Eric J G, Small, Kerrin S, Smith, Nicholas L, Sun, Yan V, Tuomilehto, Jaakko, Uitterlinden, Andre G, Vikström, Max, Vitart, Veronique, Vohl, Marie-Claude, Voight, Benjamin F, Waeber, Gerard, Wheeler, Eleanor, Widen, Elisabeth, Willemsen, Gonneke, Wilson, James F, Witteman, Jacqueline C M, Yaghootkar, Hanieh, Barroso, Ines, Watanabe, Richard M, Florez, Jose C, Meigs, James B

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Whole genome sequencing reveals that genetic conditions are frequent in intensively ill children von French, Courtney E., Delon, Isabelle, Dolling, Helen, Sanchis-Juan, Alba, Shamardina, Olga, Mégy, Karyn, Abbs, Stephen, Austin, Topun, Bowdin, Sarah, Branco, Ricardo G., Firth, Helen, Rowitch, David H., Raymond, F. Lucy

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Loss-of-function nuclear factor κB subunit 1 (NFKB1) variants are the most common monogenic cause of common variable immunodeficiency in Europeans von Tuijnenburg, Paul, Jansen, Machiel H., Carss, Keren J., Baxendale, Helen, Chandra, Anita, Seneviratne, Suranjith L., Oksenhendler, Eric, Tool, Anton T.J., Whitehorn, Deborah, Turro, Ernest, Thaventhiran, James E., Kuijpers, Taco W., Adhya, Zoe, Anantharachagan, Ariharan, Arumugakani, Gururaj, Bacchelli, Chiara, Baxendale, Helen, Bibi, Shahnaz, Booth, Claire, Browning, Michael, Burns, Siobhan, Clifford, Hayley, Cooper, Nichola, Davies, Sophie, Devlin, Lisa, Edgar, David, Egner, William, Ghurye, Rohit, Gilmour, Kimberley, Goddard, Sarah, Gordins, Pavel, Hackett, Scott, Hague, Rosie, Hayman, Grant, Jolles, Stephen, Jones, Julie, Kelleher, Peter, Klein, Nigel, Kuijpers, Taco, Kumararatne, Dinakantha, Laffan, James, Lango Allen, Hana, Lear, Sara, Longhurst, Hilary, Maimaris, Jesmeen, McDermott, Elizabeth, Morrisson, Valerie, Nasir, Iman, Noorani, Sadia, Oksenhendler, Eric, Ponsford, Mark, Qasim, Waseem, Quinn, Ellen, Quinti, Isabella, Samarghitean, Crina, Savic, Sinisa, Seneviratne, Suranjith, Simeoni, Ilenia, Staples, Emily, Steele, Cathal, Thaventhiran, James, Thomas, Moira, Thrasher, Adrian, Worth, Austen, Yong, Patrick, Bradley, John, Hammerton, Tracey, Ouwehand, Willem, Raymond, F Lucy, Veltman, Marijke, Clements-Brod, Naomi, Davis, John, Dewhurst, Eleanor, Erwood, Marie, Frary, Amy, Linger, Rachel, Papadia, Sofia, Rehnstrom, Karola, Astle, William, Attwood, Antony, Bleda, Marta, Carss, Keren, Daugherty, Louise, Deevi, Sri, Graf, Stefan, Greene, Daniel, Halmagyi, Csaba, Matser, Vera, Meacham, Stuart, Megy, Karyn, Shamardina, Olga, Titterton, Catherine, Tuna, Salih, Turro, Ernest, von Ziegenweldt, Julie, Furnell, Abigail, Staines, Simon, Stephens, Jonathan, Whitehorn, Deborah, Watt, Christopher

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Transcriptional diversity during lineage commitment of human blood progenitors von Chen, Lu, Kostadima, Myrto, Martens, Joost H. A., Canu, Giovanni, Garcia, Sara P., Turro, Ernest, Downes, Kate, Macaulay, Iain C., Bielczyk-Maczynska, Ewa, Coe, Sophia, Farrow, Samantha, Poudel, Pawan, Burden, Frances, Jansen, Sjoert B. G., Astle, William J., Attwood, Antony, Bariana, Tadbir, de Bono, Bernard, Breschi, Alessandra, Chambers, John C., Consortium, BRIDGE, Choudry, Fizzah A., Clarke, Laura, Coupland, Paul, van der Ent, Martijn, Erber, Wendy N., Jansen, Joop H., Favier, Rémi, Fenech, Matthew E., Foad, Nicola, Freson, Kathleen, van Geet, Chris, Gomez, Keith, Guigo, Roderic, Hampshire, Daniel, Kelly, Anne M., Kerstens, Hindrik H. D., Kooner, Jaspal S., Laffan, Michael, Lentaigne, Claire, Labalette, Charlotte, Martin, Tiphaine, Meacham, Stuart, Mumford, Andrew, Nürnberg, Sylvia, Palumbo, Emilio, van der Reijden, Bert A., Richardson, David, Sammut, Stephen J., Slodkowicz, Greg, Tamuri, Asif U., Vasquez, Louella, Voss, Katrin, Watt, Stephen, Westbury, Sarah, Flicek, Paul, Loos, Remco, Goldman, Nick, Bertone, Paul, Read, Randy J., Richardson, Sylvia, Cvejic, Ana, Soranzo, Nicole, Ouwehand, Willem H., Stunnenberg, Hendrik G., Frontini, Mattia, Rendon, Augusto

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Fermentation assays reveal differences in sugar and (off-) flavor metabolism across different Brettanomyces bruxellensis strains von Crauwels, Sam, Van Opstaele, Filip, Jaskula-Goiris, Barbara, Steensels, Jan, Verreth, Christel, Bosmans, Lien, Paulussen, Caroline, Herrera-Malaver, Beatriz, de Jonge, Ronnie, De Clippeleer, Jessika, Marchal, Kathleen, De Samblanx, Gorik, Willems, Kris A., Verstrepen, Kevin J., Aerts, Guido, Lievens, Bart

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De Novo Variants in CNOT1, a Central Component of the CCR4-NOT Complex Involved in Gene Expression and RNA and Protein Stability, Cause Neurodevelopmental Delay von Vissers, Lisenka E.L.M., Kalvakuri, Sreehari, de Boer, Elke, Geuer, Sinje, Oud, Machteld, van Outersterp, Inge, Kwint, Michael, Witmond, Melde, Kersten, Simone, Polla, Daniel L., Weijers, Dilys, Begtrup, Amber, McWalter, Kirsty, Ruiz, Anna, Gabau, Elisabeth, Morton, Jenny E.V., Griffith, Christopher, Weiss, Karin, Gamble, Candace, Bartley, James, Vernon, Hilary J., Brunet, Kendra, Ruivenkamp, Claudia, Kant, Sarina G., Kruszka, Paul, Larson, Austin, Afenjar, Alexandra, Billette de Villemeur, Thierry, Nugent, Kimberly, Raymond, F. Lucy, Venselaar, Hanka, Demurger, Florence, Soler-Alfonso, Claudia, Li, Dong, Bhoj, Elizabeth, Hayes, Ian, Hamilton, Nina Powell, Ahmad, Ayesha, Fisher, Rachel, van den Born, Myrthe, Willems, Marjolaine, Sorlin, Arthur, Delanne, Julian, Moutton, Sebastien, Christophe, Philippe, Mau-Them, Frederic Tran, Vitobello, Antonio, Goel, Himanshu, Massingham, Lauren, Phornphutkul, Chanika, Schwab, Jennifer, Keren, Boris, Charles, Perrine, Vreeburg, Maaike, De Simone, Lenika, Hoganson, George, Iascone, Maria, Milani, Donatella, Evenepoel, Lucie, Revencu, Nicole, Ward, D. Isum, Burns, Kaitlyn, Krantz, Ian, Raible, Sarah E., Murrell, Jill R., Wood, Kathleen, Cho, Megan T., van Bokhoven, Hans, Muenke, Maximilian, Kleefstra, Tjitske, Bodmer, Rolf, de Brouwer, Arjan P.M.

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SARS-CoV-2 spike N-terminal domain modulates TMPRSS2-dependent viral entry and fusogenicity von Meng, Bo, Choi, Jinwook, Baker, Stephen, Dougan, Gordon, Hess, Christoph, Kingston, Nathalie, Lehner, Paul J., Lyons, Paul A., Matheson, Nicholas J., Owehand, Willem H., Saunders, Caroline, Summers, Charlotte, Thaventhiran, James E.D., Toshner, Mark, Weekes, Michael P., Maxwell, Patrick, Shaw, Ashley, Calder, Jo, Canna, Laura, Domingo, Jason, Fuller, Stewart, Harris, Julie, Hewitt, Sarah, Kennet, Jane, Jose, Sherly, Kourampa, Jenny, Meadows, Anne, O’Brien, Criona, Price, Jane, Publico, Cherry, Rastall, Rebecca, Ribeiro, Carla, Rowlands, Jane, Ruffolo, Valentina, Tordesillas, Hugo, Dunmore, Benjamin J., Gräf, Stefan, Hodgson, Josh, Huang, Christopher, Hunter, Kelvin, Jones, Emma, Legchenko, Ekaterina, Matara, Cecilia, Martin, Jennifer, O’Donnell, Ciara, Pointon, Linda, Shih, Joy, Sutcliffe, Rachel, Tilly, Tobias, Treacy, Carmen, Tong, Zhen, Wylot, Marta, Betancourt, Ariana, Bower, Georgie, Cossetti, Chiara, De Sa, Aloka, Epping, Madeline, Gleadall, Nick, Hinch, Andrew, Jackson, Sarah, Jarvis, Isobel, Krishna, Ben, Omarjee, Ommar, Perera, Marianne, Potts, Martin, Richoz, Nathan, Romashova, Veronika, Stefanucci, Luca, Strezlecki, Mateusz, Turner, Lori, De Bie, Eckart M.D.D., Bunclark, Katherine, Josipovic, Masa, Mackay, Michael, Allison, John, Butcher, Helen, Caputo, Daniela, Dewhurst, Eleanor, Furlong, Anita, Graves, Barbara, Gray, Jennifer, Ivers, Tasmin, Le Gresley, Emma, Linger, Rachel, Meloy, Sarah, Muldoon, Francesca, Ovington, Nigel, Papadia, Sofia, Stark, Hannah, Stirrups, Kathleen E., Townsend, Paul, Walker, Neil, Webster, Jennifer, Scholtes, Ingrid, Hein, Sabine, King, Rebecca, Bradley, John R., Smith, Kenneth G.C., Lee, Joo Hyeon, Gupta, Ravindra K.

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