A role for Regulator of G protein Signaling-12 (RGS12) in the balance between myoblast proliferation and differentiation von Schroer, Adam B, Mohamed, Junaith S, Willard, Melinda D, Setola, Vincent, Oestreich, Emily, Siderovski, David P

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Genomic characterization of intrinsic and acquired resistance to cetuximab in colorectal cancer patients von Bray, Steven M., Lee, Jeeyun, Kim, Seung Tae, Hur, Joon Young, Ebert, Philip J., Calley, John N., Wulur, Isabella H., Gopalappa, Thejaswini, Wong, Swee Seong, Qian, Hui-Rong, Ting, Jason C., Liu, Jiangang, Willard, Melinda D., Novosiadly, Ruslan D., Park, Young Suk, Park, Joon Oh, Lim, Ho Yeong, Kang, Won Ki, Aggarwal, Amit, Kim, Hee Cheol, Reinhard, Christoph

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A Phase I Study of LY3009120, a Pan-RAF Inhibitor, in Patients with Advanced or Metastatic Cancer von Sullivan, Ryan J, Hollebecque, Antoine, Flaherty, Keith T, Shapiro, Geoffrey I, Rodon Ahnert, Jordi, Millward, Michael J, Zhang, Wei, Gao, Ling, Sykes, Amanda, Willard, Melinda D, Yu, Danni, Schade, Andrew E, Crowe, KrisAnne, Flynn, Daniel L, Kaufman, Michael D, Henry, James R, Peng, Sheng-Bin, Benhadji, Karim A, Conti, Ilaria, Gordon, Michael S, Tiu, Ramon V, Hong, David S

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A phase I study of LY3164530, a bispecific antibody targeting MET and EGFR, in patients with advanced or metastatic cancer von Patnaik, Amita, Gordon, Michael, Tsai, Frank, Papadopoulous, Kyri, Rasco, Drew, Beeram, S. Muralidhar, Fu, Siqing, Janku, Filip, Hynes, Scott M., Gundala, Sushma R., Willard, Melinda D., Zhang, Wei, Lin, Aimee Bence, Hong, David

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Combined CDK4/6 and ERK1/2 Inhibition Enhances Antitumor Activity in NF1-Associated Plexiform Neurofibroma von Flint, Alyssa C, Mitchell, Dana K, Angus, Steven P, Smith, Abbi E, Bessler, Waylan, Jiang, Li, Mang, Henry, Li, Xiaohong, Lu, Qingbo, Rodriguez, Brooke, Sandusky, George E, Masters, Andi R, Zhang, Chi, Dang, Pengtao, Koenig, Jenna, Johnson, Gary L, Shen, Weihua, Liu, Jiangang, Aggarwal, Amit, Donoho, Gregory P, Willard, Melinda D, Bhagwat, Shripad V, Clapp, D Wade, Rhodes, Steven D

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Phase 1 cohort expansion study of LY3023414, a dual PI3K/mTOR inhibitor, in patients with advanced mesothelioma von Zauderer, Marjorie G., Alley, Evan W., Bendell, Johanna, Capelletto, Enrica, Bauer, Todd M., Callies, Sophie, Szpurka, Anna M., Kang, Suhyun, Willard, Melinda D., Wacheck, Volker, Varghese, Anna M.

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A phase 1 study of LY3076226, a fibroblast growth factor receptor 3 (FGFR3) antibody–drug conjugate, in patients with advanced or metastatic cancer von Kollmannsberger, Christian, Britten, Carolyn D., Olszanski, Anthony J., Walker, Joan Andrews, Zang, Wei, Willard, Melinda D., Radtke, David B., Farrington, Daphne L., Bell-McGuinn, Katherine M., Patnaik, Amita

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Merestinib (LY2801653) inhibits neurotrophic receptor kinase (NTRK) and suppresses growth of NTRK fusion bearing tumors von Konicek, Bruce W, Capen, Andrew R, Credille, Kelly M, Ebert, Philip J, Falcon, Beverly L, Heady, Gary L, Patel, Bharvin K R, Peek, Victoria L, Stephens, Jennifer R, Stewart, Julie A, Stout, Stephanie L, Timm, David E, Um, Suzane L, Willard, Melinda D, Wulur, Isabella H, Zeng, Yi, Wang, Yong, Walgren, Richard A, Betty Yan, Sau-Chi

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A P-loop mutation in Gα subunits prevents transition to the active state: implications for G-protein signaling in fungal pathogenesis von Bosch, Dustin E, Willard, Francis S, Ramanujam, Ravikrishna, Kimple, Adam J, Willard, Melinda D, Naqvi, Naweed I, Siderovski, David P

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Regulator of G-protein signaling 14 (RGS14) is a selective H-Ras effector von Willard, Francis S, Willard, Melinda D, Kimple, Adam J, Soundararajan, Meera, Oestreich, Emily A, Li, Xiaoyan, Sowa, Nathaniel A, Kimple, Randall J, Doyle, Declan A, Der, Channing J, Zylka, Mark J, Snider, William D, Siderovski, David P

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Selective role for RGS12 as a Ras/Raf/MEK scaffold in nerve growth factor-mediated differentiation von Willard, Melinda D, Willard, Francis S, Li, Xiaoyan, Cappell, Steven D, Snider, William D, Siderovski, David P

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Somatic Mutations in GRM1 in Cancer Alter Metabotropic Glutamate Receptor 1 Intracellular Localization and Signaling von Esseltine, Jessica L., Willard, Melinda D., Wulur, Isabella H., Lajiness, Mary E., Barber, Thomas D., Ferguson, Stephen S.G.

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Correction to: A phase I study of LY3164530, a bispecific antibody targeting MET and EGFR, in patients with advanced or metastatic cancer von Patnaik, Amita, Gordon, Michael, Tsai, Frank, Papadopoulos, Kyriakos P., Rasco, Drew, Beeram, Muralidhar, Fu, Siqing, Janku, Filip, Hynes, Scott M., Gundala, Sushma R., Willard, Melinda D., Zhang, Wei, Lin, Aimee Bence, Hong, David

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A P-loop Mutation in G[alpha] Subunits Prevents Transition to the Active State: Implications for G-protein Signaling in Fungal Pathogenesis von Bosch, Dustin E, Willard, Francis S, Ramanujam, Ravikrishna, Kimple, Adam J, Willard, Melinda D, Naqvi, Naweed I, Siderovski, David P

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Point Mutation to Gαi Selectively Blocks GoLoco Motif Binding: DIRECT EVIDENCE FOR Gα·GoLoco COMPLEXES IN MITOTIC SPINDLE DYNAMICS von Willard, Francis S, Zheng, Zhen, Guo, Juan, Digby, Gregory J, Kimple, Adam J, Conley, Jason M, Johnston, Christopher A, Bosch, Dustin, Willard, Melinda D, Watts, Val J, Lambert, Nevin A, Ikeda, Stephen R, Du, Quansheng, Siderovski, David P

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Somatic mutations in CCK2R alter receptor activity that promote oncogenic phenotypes von Willard, Melinda D, Lajiness, Mary E, Wulur, Isabella H, Feng, Bo, Swearingen, Michelle L, Uhlik, Mark T, Kinzler, Kenneth W, Velculescu, Victor E, Sjöblom, Tobias, Markowitz, Sanford D, Powell, Steven M, Vogelstein, Bert, Barber, Thomas D

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A sweet cycle for Arabidopsis G-proteins: Recent discoveries and controversies in plant G-protein signal transduction von Johnston, Christopher A., Willard, Melinda D., Kimple, Adam J., Siderovski, David P., Willard, Francis S.

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Whole-genome sequencing identifies recurrent mutations in hepatocellular carcinoma von Kan, Zhengyan, Zheng, Hancheng, Liu, Xiao, Li, Shuyu, Barber, Thomas D, Gong, Zhuolin, Gao, Huan, Hao, Ke, Willard, Melinda D, Xu, Jiangchun, Hauptschein, Robert, Rejto, Paul A, Fernandez, Julio, Wang, Guan, Zhang, Qinghui, Wang, Bo, Chen, Ronghua, Wang, Jian, Lee, Nikki P, Zhou, Wei, Lin, Zhao, Peng, Zhiyu, Yi, Kang, Chen, Shengpei, Li, Lin, Fan, Xiaomei, Yang, Jie, Ye, Rui, Ju, Jia, Wang, Kai, Estrella, Heather, Deng, Shibing, Wei, Ping, Qiu, Ming, Wulur, Isabella H, Liu, Jiangang, Ehsani, Mariam E, Zhang, Chunsheng, Loboda, Andrey, Sung, Wing Kin, Aggarwal, Amit, Poon, Ronnie T, Fan, Sheung Tat, Wang, Jun, Hardwick, James, Reinhard, Christoph, Dai, Hongyue, Li, Yingrui, Luk, John M, Mao, Mao

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A role for Regulator of G protein Signaling-12 von Schroer, Adam B, Mohamed, Junaith S, Willard, Melinda D, Setola, Vincent, Oestreich, Emily, Siderovski, David P

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Clinicogenomic factors and treatment patterns among patients with advanced non–small cell lung cancer with or without brain metastases in the United States von Smyth, Emily Nash, John, Jincy, Tiu, Ramon V, Willard, Melinda Dale, Beyrer, Julie Kay, Bowman, Lee, Sheffield, Kristin M, Han, Yimei, Brastianos, Priscilla K

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