A general strategy for diversifying complex natural products to polycyclic scaffolds with medium-sized rings von Zhao, Changgui, Ye, Zhengqing, Ma, Zhi-xiong, Wildman, Scott A., Blaszczyk, Stephanie A., Hu, Lihong, Guizei, Ilia A., Tang, Weiping

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Machine Learning Consensus Scoring Improves Performance Across Targets in Structure-Based Virtual Screening von Ericksen, Spencer S, Wu, Haozhen, Zhang, Huikun, Michael, Lauren A, Newton, Michael A, Hoffmann, F. Michael, Wildman, Scott A

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Discovery and Mechanism of Small Molecule Inhibitors Selective for the Chromatin-Binding Domains of Oncogenic UHRF1 von Liu, Wallace H, Miner, 3rd, Robert E, Albaugh, Brittany N, Ananiev, Gene E, Wildman, Scott A, Denu, John M

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Optimizing Small Molecule Inhibitors of Calcium-Dependent Protein Kinase 1 to Prevent Infection by Toxoplasma gondii von Lourido, Sebastian, Zhang, Chao, Lopez, Michael S, Tang, Keliang, Barks, Jennifer, Wang, Qiuling, Wildman, Scott A, Shokat, Kevan M, Sibley, L. David

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Predicting kinase inhibitors using bioactivity matrix derived informer sets von Zhang, Huikun, Ericksen, Spencer S, Lee, Ching-Pei, Ananiev, Gene E, Wlodarchak, Nathan, Yu, Peng, Mitchell, Julie C, Gitter, Anthony, Wright, Stephen J, Hoffmann, F Michael, Wildman, Scott A, Newton, Michael A

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Structure-based discovery of small molecule hepsin and HGFA protease inhibitors: Evaluation of potency and selectivity derived from distinct binding pockets von Franco, Francisco M., Jones, Darin E., Harris, Peter K.W., Han, Zhenfu, Wildman, Scott A., Jarvis, Cassie M., Janetka, James W.

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Inhibitors of HGFA, Matriptase, and Hepsin Serine Proteases: A Nonkinase Strategy to Block Cell Signaling in Cancer von Han, Zhenfu, Harris, Peter K. W, Jones, Darin E, Chugani, Ryan, Kim, Tommy, Agarwal, Manjula, Shen, Wei, Wildman, Scott A, Janetka, James W

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Identification of 4-Amino-Thieno[2,3- d ]Pyrimidines as QcrB Inhibitors in Mycobacterium tuberculosis von Harrison, Gregory A, Mayer Bridwell, Anne E, Singh, Megh, Jayaraman, Keshav, Weiss, Leslie A, Kinsella, Rachel L, Aneke, Janessa S, Flentie, Kelly, Schene, Miranda E, Gaggioli, Margaret, Solomon, Samantha D, Wildman, Scott A, Meyers, Marvin J, Stallings, Christina L

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Prediction of Physicochemical Parameters by Atomic Contributions von Wildman, Scott A, Crippen, Gordon M

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Identification of a novel class of RIP1/RIP3 dual inhibitors that impede cell death and inflammation in mouse abdominal aortic aneurysm models von Zhou, Ting, Wang, Qiwei, Phan, Noel, Ren, Jun, Yang, Huan, Feldman, Conner C., Feltenberger, John B., Ye, Zhengqing, Wildman, Scott A., Tang, Weiping, Liu, Bo

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Practical Model Selection for Prospective Virtual Screening von Liu, Shengchao, Alnammi, Moayad, Ericksen, Spencer S, Voter, Andrew F, Ananiev, Gene E, Keck, James L, Hoffmann, F. Michael, Wildman, Scott A, Gitter, Anthony

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Evaluating Scalable Supervised Learning for Synthesize-on-Demand Chemical Libraries von Alnammi, Moayad, Liu, Shengchao, Ericksen, Spencer S., Ananiev, Gene E., Voter, Andrew F., Guo, Song, Keck, James L., Hoffmann, F. Michael, Wildman, Scott A., Gitter, Anthony

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Structure-Based Drug Design and Optimization of Mannoside Bacterial FimH Antagonists von Han, Zhenfu, Pinkner, Jerome S, Ford, Bradley, Obermann, Robert, Nolan, William, Wildman, Scott A, Hobbs, Doug, Ellenberger, Tom, Cusumano, Corinne K, Hultgren, Scott J, Janetka, James W

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Small Molecule Antagonists of the DNA Repair ERCC1/XPA Protein‐Protein Interaction von Obermann, Robert, Yemane, Bereket, Jarvis, Cassie, Franco, Francisco M., Kyriukha, Yevhenii, Nolan, William, Gohara, Beth, Krezel, Andrzej M., Wildman, Scott A., Janetka, James W.

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Identification of small molecule enzyme inhibitors as broad-spectrum anthelmintics von Tyagi, Rahul, Elfawal, Mostafa A., Wildman, Scott A., Helander, Jon, Bulman, Christina A., Sakanari, Judy, Rosa, Bruce A., Brindley, Paul J., Janetka, James W., Aroian, Raffi V., Mitreva, Makedonka

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Piperidine carbamate peptidomimetic inhibitors of the serine proteases HGFA, matriptase and hepsin von Damalanka, Vishnu C, Wildman, Scott A, Janetka, James W

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Tumor-Specific Binding of Radiolabeled PEGylated GIRLRG Peptide: A Novel Agent for Targeting Cancers von Kapoor, Vaishali, Dadey, David Y A, Nguyen, Kim, Wildman, Scott A, Hoye, Kelly, Khudanyan, Arpine, Bandara, Nilantha, Rogers, Buck E, Thotala, Dinesh, Hallahan, Dennis E

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[alpha]-Ketobenzothiazole Serine Protease Inhibitors of Aberrant HGF/c-MET and MSP/RON Kinase Pathway Signaling in Cancer von Han, Zhenfu, Harris, Peter K W, Karmakar, Partha, Kim, Tommy, Owusu, Ben Y, Wildman, Scott A, Klampfer, Lidija, Janetka, James W

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α-Ketobenzothiazole Serine Protease Inhibitors of Aberrant HGF/c-MET and MSP/RON Kinase Pathway Signaling in Cancer von Han, Zhenfu, Harris, Peter K. W., Karmakar, Partha, Kim, Tommy, Owusu, Ben Y., Wildman, Scott A., Klampfer, Lidija, Janetka, James W.

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Isoform-selective inhibition of facilitative glucose transporters: elucidation of the molecular mechanism of HIV protease inhibitor binding von Hresko, Richard C, Kraft, Thomas E, Tzekov, Anatoly, Wildman, Scott A, Hruz, Paul W

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