Transcription imparts architecture, function and logic to enhancer units von Tippens, Nathaniel D., Liang, Jin, Leung, Alden King-Yung, Wierbowski, Shayne D., Ozer, Abdullah, Booth, James G., Lis, John T., Yu, Haiyuan

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Cross‐docking benchmark for automated pose and ranking prediction of ligand binding von Wierbowski, Shayne D., Wingert, Bentley M., Zheng, Jim, Camacho, Carlos J.

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Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations von Fragoza, Robert, Das, Jishnu, Wierbowski, Shayne D., Liang, Jin, Tran, Tina N., Liang, Siqi, Beltran, Juan F., Rivera-Erick, Christen A., Ye, Kaixiong, Wang, Ting-Yi, Yao, Li, Mort, Matthew, Stenson, Peter D., Cooper, David N., Wei, Xiaomu, Keinan, Alon, Schimenti, John C., Clark, Andrew G., Yu, Haiyuan

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A 3D structural SARS-CoV-2–human interactome to explore genetic and drug perturbations von Wierbowski, Shayne D., Liang, Siqi, Liu, Yuan, Chen, You, Gupta, Shagun, Andre, Nicole M., Lipkin, Steven M., Whittaker, Gary R., Yu, Haiyuan

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Structure-based validation can drastically underestimate error rate in proteome-wide cross-linking mass spectrometry studies von Yugandhar, Kumar, Wang, Ting-Yi, Wierbowski, Shayne D., Shayhidin, Elnur Elyar, Yu, Haiyuan

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A full-proteome, interaction-specific characterization of mutational hotspots across human cancers von Chen, Siwei, Liu, Yuan, Zhang, Yingying, Wierbowski, Shayne D, Lipkin, Steven M, Wei, Xiaomu, Yu, Haiyuan

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Combining views for newly sequenced organisms von Zhang, Yingying, Wierbowski, Shayne D., Yu, Haiyuan

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A massively parallel barcoded sequencing pipeline enables generation of the first ORFeome and interactome map for rice von Wierbowski, Shayne D., Vob, Tommy V., Falter-Braun, Pascal, Jobe, Timothy O., Kruse, Lars H., Wei, Xiaomu, Liang, Jin, Meyer, Michael J., Akturk, Nurten, Rivera-Erick, Christen A., Cordero, Nicolas A., Paramo, Mauricio I., Shayhidin, Elnur E., Bertolotti, Marta, Tippens, Nathaniel D., Akther, Kazi, Sharma, Rita, Katayose, Yuichi, Salehi-Ashtiani, Kourosh, Hao, Tong, Ronald, Pamela C., Ecker, Joseph R., Schweitzer, Peter A., Kikuchi, Shoshi, Mizuno, Hiroshi, Hill, David E., Vidal, Marc, Moghe, Gaurav D., McCouch, Susan R., Yu, Haiyuan

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BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain von Pourhaghighi, Reza, Ash, Peter E.A., Phanse, Sadhna, Goebels, Florian, Hu, Lucas Z.M., Chen, Siwei, Zhang, Yingying, Wierbowski, Shayne D., Boudeau, Samantha, Moutaoufik, Mohamed T., Malty, Ramy H., Malolepsza, Edyta, Tsafou, Kalliopi, Nathan, Aparna, Cromar, Graham, Guo, Hongbo, Abdullatif, Ali Al, Apicco, Daniel J., Becker, Lindsay A., Gitler, Aaron D., Pulst, Stefan M., Youssef, Ahmed, Hekman, Ryan, Havugimana, Pierre C., White, Carl A., Blum, Benjamin C., Ratti, Antonia, Bryant, Camron D., Parkinson, John, Lage, Kasper, Babu, Mohan, Yu, Haiyuan, Bader, Gary D., Wolozin, Benjamin, Emili, Andrew

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Extracting complementary insights from molecular phenotypes for prioritization of disease-associated mutations von Wierbowski, Shayne D., Fragoza, Robert, Liang, Siqi, Yu, Haiyuan

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BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain von Pourhaghighi, Reza, Ash, Peter E.A., Phanse, Sadhna, Goebels, Florian, Hu, Lucas Z.M., Chen, Siwei, Zhang, Yingying, Wierbowski, Shayne D., Boudeau, Samantha, Moutaoufik, Mohamed T., Malty, Ramy H., Malolepsza, Edyta, Tsafou, Kalliopi, Nathan, Aparna, Cromar, Graham, Guo, Hongbo, Al Abdullatif, Ali, Apicco, Daniel J., Becker, Lindsay A., Gitler, Aaron D., Pulst, Stefan M., Youssef, Ahmed, Hekman, Ryan, Havugimana, Pierre C., White, Carl A., Blum, Benjamin C., Ratti, Antonia, Bryant, Camron D., Parkinson, John, Lage, Kasper, Babu, Mohan, Yu, Haiyuan, Bader, Gary D., Wolozin, Benjamin, Emili, Andrew

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Deep learning methods for 3D structural proteome and interactome modeling von Lee, Dongjin, Xiong, Dapeng, Wierbowski, Shayne, Li, Le, Liang, Siqi, Yu, Haiyuan

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A comprehensive SARS-CoV-2–human protein–protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets von Zhou, Yadi, Liu, Yuan, Gupta, Shagun, Paramo, Mauricio I., Hou, Yuan, Mao, Chengsheng, Luo, Yuan, Judd, Julius, Wierbowski, Shayne, Bertolotti, Marta, Nerkar, Mriganka, Jehi, Lara, Drayman, Nir, Nicolaescu, Vlad, Gula, Haley, Tay, Savaş, Randall, Glenn, Wang, Peihui, Lis, John T., Feschotte, Cédric, Erzurum, Serpil C., Cheng, Feixiong, Yu, Haiyuan

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Structure-based validation can drastically under-estimate error rate in proteome-wide cross-linking mass spectrometry studies von Yugandhar, Kumar, Wang, Ting-Yi, Wierbowski, Shayne D., Shayhidin, Elnur Elyar, Yu, Haiyuan

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Protein Disulfide Stress: Proposed Radical‐Free Bridges to Neurodegeneration von Foley, Timothy, Cantarella, Kristen, Gillespie, Paul, Wierbowski, Shayne

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Genetics of extreme human longevity to guide drug discovery for healthy ageing von Zhang, Zhengdong D., Milman, Sofiya, Lin, Jhih-Rong, Wierbowski, Shayne, Yu, Haiyuan, Barzilai, Nir, Gorbunova, Vera, Ladiges, Warren C., Niedernhofer, Laura J., Suh, Yousin, Robbins, Paul D., Vijg, Jan

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