Non-canonical functions of SNAIL drive context-specific cancer progression von Paul, Mariel C., Schneeweis, Christian, Falcomatà, Chiara, Shan, Chuan, Rossmeisl, Daniel, Koutsouli, Stella, Klement, Christine, Zukowska, Magdalena, Widholz, Sebastian A., Jesinghaus, Moritz, Heuermann, Konstanze K., Engleitner, Thomas, Seidler, Barbara, Sleiman, Katia, Steiger, Katja, Tschurtschenthaler, Markus, Walter, Benjamin, Weidemann, Sören A., Pietsch, Regina, Schnieke, Angelika, Schmid, Roland M., Robles, Maria S., Andrieux, Geoffroy, Boerries, Melanie, Rad, Roland, Schneider, Günter, Saur, Dieter

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Genome‐wide cooperation of EMT transcription factor ZEB1 with YAP and AP‐1 in breast cancer von Feldker, Nora, Ferrazzi, Fulvia, Schuhwerk, Harald, Widholz, Sebastian A, Guenther, Kerstin, Frisch, Isabell, Jakob, Kathrin, Kleemann, Julia, Riegel, Dania, Bönisch, Ulrike, Lukassen, Sören, Eccles, Rebecca L, Schmidl, Christian, Stemmler, Marc P, Brabletz, Thomas, Brabletz, Simone

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An integrated cellular and molecular model of gastric neuroendocrine cancer evolution highlights therapeutic targets von Griger, Joscha, Widholz, Sebastian A., Jesinghaus, Moritz, de Andrade Krätzig, Niklas, Lange, Sebastian, Engleitner, Thomas, Montero, Juan José, Zhigalova, Ekaterina, Öllinger, Rupert, Suresh, Veveeyan, Winkler, Wiebke, Lier, Svenja, Baranov, Olga, Trozzo, Riccardo, Ben Khaled, Najib, Chakraborty, Shounak, Yu, Jiakun, Konukiewitz, Björn, Steiger, Katja, Pfarr, Nicole, Rajput, Ashish, Sailer, David, Keller, Gisela, Schirmacher, Peter, Röcken, Christoph, Fagerstedt, Klaus W., Mayerle, Julia, Schmidt-Supprian, Marc, Schneider, Günter, Weichert, Wilko, Calado, Dinis P., Sommermann, Thomas, Klöppel, Günter, Rajewsky, Klaus, Saur, Dieter, Rad, Roland

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Genetically Engineered Mouse Models of Liver Tumorigenesis Reveal a Wide Histological Spectrum of Neoplastic and Non-Neoplastic Liver Lesions von Steiger, Katja, Gross, Nina, Widholz, Sebastian A., Rad, Roland, Weichert, Wilko, Mogler, Carolin

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CRISPR somatic genome engineering and cancer modeling in the mouse pancreas and liver von Kaltenbacher, Thorsten, Löprich, Jessica, Maresch, Roman, Weber, Julia, Müller, Sebastian, Oellinger, Rupert, Groß, Nina, Griger, Joscha, de Andrade Krätzig, Niklas, Avramopoulos, Petros, Ramanujam, Deepak, Brummer, Sabine, Widholz, Sebastian A., Bärthel, Stefanie, Falcomatà, Chiara, Pfaus, Anja, Alnatsha, Ahmed, Mayerle, Julia, Schmidt-Supprian, Marc, Reichert, Maximilian, Schneider, Günter, Ehmer, Ursula, Braun, Christian J., Saur, Dieter, Engelhardt, Stefan, Rad, Roland

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Copy number variation of two separate regulatory regions upstream of SOX9 causes isolated 46,XY or 46,XX disorder of sex development von Kim, Gwang-Jin, Sock, Elisabeth, Buchberger, Astrid, Just, Walter, Denzer, Friederike, Hoepffner, Wolfgang, German, James, Cole, Trevor, Mann, Jillian, Seguin, John H, Zipf, William, Costigan, Colm, Schmiady, Hardi, Rostásy, Moritz, Kramer, Mildred, Kaltenbach, Simon, Rösler, Bernd, Georg, Ina, Troppmann, Elke, Teichmann, Anne-Christin, Salfelder, Anika, Widholz, Sebastian A, Wieacker, Peter, Hiort, Olaf, Camerino, Giovanna, Radi, Orietta, Wegner, Michael, Arnold, Hans-Henning, Scherer, Gerd

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Selective multi-kinase inhibition sensitizes mesenchymal pancreatic cancer to immune checkpoint blockade by remodeling the tumor microenvironment von Falcomatà, Chiara, Bärthel, Stefanie, Widholz, Sebastian A, Schneeweis, Christian, Montero, Juan José, Toska, Albulena, Mir, Jonas, Kaltenbacher, Thorsten, Heetmeyer, Jeannine, Swietlik, Jonathan J, Cheng, Jing-Yuan, Teodorescu, Bianca, Reichert, Oliver, Schmitt, Constantin, Grabichler, Kathrin, Coluccio, Andrea, Boniolo, Fabio, Veltkamp, Christian, Zukowska, Magdalena, Vargas, Angelica Arenas, Paik, Woo Hyun, Jesinghaus, Moritz, Steiger, Katja, Maresch, Roman, Öllinger, Rupert, Ammon, Tim, Baranov, Olga, Robles, Maria S, Rechenberger, Julia, Kuster, Bernhard, Meissner, Felix, Reichert, Maximilian, Flossdorf, Michael, Rad, Roland, Schmidt-Supprian, Marc, Schneider, Günter, Saur, Dieter

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TRAIL Receptor Targeting Agents Potentiate PARP Inhibitor Efficacy in Pancreatic Cancer Independently of BRCA2 Mutation Status von Ben Khaled, Najib, Hammer, Katharina, Ye, Liangtao, Alnatsha, Ahmed, Widholz, Sebastian A., Piseddu, Ignazio, Sirtl, Simon, Schneider, Julia, Munker, Stefan, Mahajan, Ujjwal Mukund, Montero, Juan José, Griger, Joscha, Mayerle, Julia, Reiter, Florian P., De Toni, Enrico N.

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Genome‐wide cooperation of EMT transcription factor ZEB 1 with YAP and AP ‐1 in breast cancer von Feldker, Nora, Ferrazzi, Fulvia, Schuhwerk, Harald, Widholz, Sebastian A, Guenther, Kerstin, Frisch, Isabell, Jakob, Kathrin, Kleemann, Julia, Riegel, Dania, Bönisch, Ulrike, Lukassen, Sören, Eccles, Rebecca L, Schmidl, Christian, Stemmler, Marc P, Brabletz, Thomas, Brabletz, Simone

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TRAIL Receptor Targeting Agents Potentiate PARP Inhibitor Efficacy in Pancreatic Cancer Independently of IBRCA2/I Mutation Status von Ben Khaled, Najib, Hammer, Katharina, Ye, Liangtao, Alnatsha, Ahmed, Widholz, Sebastian A, Piseddu, Ignazio, Sirtl, Simon, Schneider, Julia, Munker, Stefan, Mahajan, Ujjwal Mukund, Montero, Juan José, Griger, Joscha, Mayerle, Julia, Reiter, Florian P, De Toni, Enrico N

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Abstract 2514: Pancreatic cancer subtype-specific secreted factors determine the immunosuppressive tumor microenvironment von Bärthel, Stefanie, Falcomatà, Chiara, Widholz, Sebastian A., Toska, Albulena, Boniolo, Fabio, Schmitt, Constantin, Gölling, Vanessa, Swietlik, Jonathan, Mir, Jonas, Jesinghaus, Moritz, Meissner, Felix, Rad, Roland, Schmidt-Supprian, Marc, Saur, Dieter

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TRAIL Receptor Targeting Agents Potentiate PARP Inhibitor Efficacy in Pancreatic Cancer Independently of BRCA2 Mutation Status von Ben Khaled, Najib, Hammer, Katharina, Ye, Liangtao, Alnatsha, Ahmed, Widholz, Sebastian A, Piseddu, Ignazio, Sirtl, Simon, Schneider, Julia, Munker, Stefan, Mahajan, Ujjwal Mukund, Montero, Juan Jose, Griger, Joscha, Mayerle, Julia, Reiter, Florian P, De Toni, Enrico N

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Copy number variation of two separate regulatory regions upstream of SOX9 causes isolated 46,XY or 46,XX disorder of sex development von Kim, Gwang-Jin

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Mutant GNAS drives pancreatic tumourigenesis by inducing PKA-mediated SIK suppression and reprogramming lipid metabolism von Patra, Krushna C., Kato, Yasutaka, Mizukami, Yusuke, Widholz, Sebastian, Boukhali, Myriam, Revenco, Iulia, Grossman, Elizabeth A., Ji, Fei, Sadreyev, Ruslan I., Liss, Andrew S., Screaton, Robert A., Sakamoto, Kei, Ryan, David P., Mino-Kenudson, Mari, Castillo, Carlos Fernandez-del, Nomura, Daniel K., Haas, Wilhelm, Bardeesy, Nabeel

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Mutant GNAS drives pancreatic tumorigenesis by inducing PKA-mediated SIK suppression and reprogramming lipid metabolism von Patra, Krushna C., Kato, Yasutaka, Mizukami, Yusuke, Widholz, Sebastian, Boukhali, Myriam, Revenco, Iulia, Grossman, Elizabeth A., Ji, Fei, Sadreyev, Ruslan I., Liss, Andrew S., Screaton, Robert A., Sakamoto, Kei, Ryan, David P., Mino-Kenudson, Mari, Castillo, Carlos Fernandez-del, Nomura, Daniel K., Haas, Wilhelm, Bardeesy, Nabeel

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Supplementary table 2.xlsx von Krushna Patra, Kato, Yasutaka, Mizukami, Yusuke, Widholz, Sebastian, Boukhali, Myriam, Revenco, Iulia, Grossman, Elizabeth A., Ji, Fei, Sadreyev, Ruslan I., Liss, Andrew S., Screaton, Robert A., Sakamoto, Kei, Ryan, David P., Mino-Kenudson, Mari, Castillo, Carlos Fernandez-Del, Nomura, Daniel K., Haas, Wilhelm, Bardeesy, Nabeel

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Supplementary table 3 von Krushna Patra, Kato, Yasutaka, Mizukami, Yusuke, Widholz, Sebastian, Boukhali, Myriam, Revenco, Iulia, Grossman, Elizabeth A., Ji, Fei, Sadreyev, Ruslan I., Liss, Andrew S., Screaton, Robert A., Sakamoto, Kei, Ryan, David P., Mino-Kenudson, Mari, Castillo, Carlos Fernandez-Del, Nomura, Daniel K., Haas, Wilhelm, Bardeesy, Nabeel

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