MK2 Phosphorylates RIPK1 to Prevent TNF-Induced Cell Death von Jaco, Isabel, Annibaldi, Alessandro, Lalaoui, Najoua, Wilson, Rebecca, Tenev, Tencho, Laurien, Lucie, Kim, Chun, Jamal, Kunzah, Wicky John, Sidonie, Liccardi, Gianmaria, Chau, Diep, Murphy, James M., Brumatti, Gabriela, Feltham, Rebecca, Pasparakis, Manolis, Silke, John, Meier, Pascal

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SUMO-mediated regulation of NLRP3 modulates inflammasome activity von Barry, Rachael, John, Sidonie Wicky, Liccardi, Gianmaria, Tenev, Tencho, Jaco, Isabel, Chen, Chih-Hong, Choi, Justin, Kasperkiewicz, Paulina, Fernandes-Alnemri, Teresa, Alnemri, Emad, Drag, Marcin, Chen, Yuan, Meier, Pascal

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Ubiquitin-Mediated Regulation of RIPK1 Kinase Activity Independent of IKK and MK2 von Annibaldi, Alessandro, Wicky John, Sidonie, Vanden Berghe, Tom, Swatek, Kirby N., Ruan, Jianbin, Liccardi, Gianmaria, Bianchi, Katiuscia, Elliott, Paul R., Choi, Sze Men, Van Coillie, Samya, Bertin, John, Wu, Hao, Komander, David, Vandenabeele, Peter, Silke, John, Meier, Pascal

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Ubiquitylation of MLKL at lysine 219 positively regulates necroptosis-induced tissue injury and pathogen clearance von Garcia, Laura Ramos, Tenev, Tencho, Newman, Richard, Haich, Rachel O., Liccardi, Gianmaria, John, Sidonie Wicky, Annibaldi, Alessandro, Yu, Lu, Pardo, Mercedes, Young, Samuel N., Fitzgibbon, Cheree, Fernando, Winnie, Guppy, Naomi, Kim, Hyojin, Liang, Lung-Yu, Lucet, Isabelle S., Kueh, Andrew, Roxanis, Ioannis, Gazinska, Patrycja, Sims, Martin, Smyth, Tomoko, Ward, George, Bertin, John, Beal, Allison M., Geddes, Brad, Choudhary, Jyoti S., Murphy, James M., Aurelia Ball, K., Upton, Jason W., Meier, Pascal

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CARD-Mediated Autoinhibition of cIAP1's E3 Ligase Activity Suppresses Cell Proliferation and Migration von Lopez, Juanita, John, Sidonie Wicky, Tenev, Tencho, Rautureau, Gilles J.P., Hinds, Mark G., Francalanci, Floriana, Wilson, Rebecca, Broemer, Meike, Santoro, Massimo M., Day, Catherine L., Meier, Pascal

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Mind Bomb Regulates Cell Death during TNF Signaling by Suppressing RIPK1’s Cytotoxic Potential von Feltham, Rebecca, Jamal, Kunzah, Tenev, Tencho, Liccardi, Gianmaria, Jaco, Isabel, Domingues, Celia Monteiro, Morris, Otto, John, Sidonie Wicky, Annibaldi, Alessandro, Widya, Marcella, Kearney, Conor J., Clancy, Danielle, Elliott, Paul R., Glatter, Timo, Qiao, Qi, Thompson, Andrew J., Nesvizhskii, Alexey, Schmidt, Alexander, Komander, David, Wu, Hao, Martin, Seamus, Meier, Pascal

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Molecular Interactions of Yeast Neo1p, an Essential Member of the Drs2 Family of Aminophospholipid Translocases, and Its Role in Membrane Trafficking within the Endomembrane System von Wicky, Sidonie, Schwarz, Heinz, Singer-Krüger, Birgit

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The unconventional myosin CRINKLED and its mammalian orthologue MYO7A regulate caspases in their signalling roles von Orme, Mariam H., Liccardi, Gianmaria, Moderau, Nina, Feltham, Rebecca, Wicky-John, Sidonie, Tenev, Tencho, Aram, Lior, Wilson, Rebecca, Bianchi, Katiuscia, Morris, Otto, Monteiro Domingues, Celia, Robertson, David, Tare, Meghana, Wepf, Alexander, Williams, David, Bergmann, Andreas, Gstaiger, Matthias, Arama, Eli, Ribeiro, Paulo S., Meier, Pascal

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A RIPK1-specific PROTAC degrader achieves potent antitumor activity by enhancing immunogenic cell death von Mannion, Jonathan, Gifford, Valentina, Bellenie, Benjamin, Fernando, Winnie, Ramos Garcia, Laura, Wilson, Rebecca, John, Sidonie Wicky, Udainiya, Savita, Patin, Emmanuel C., Tiu, Crescens, Smith, Angel, Goicoechea, Maria, Craxton, Andrew, Moraes de Vasconcelos, Nathalia, Guppy, Naomi, Cheung, Kwai-Ming J., Cundy, Nicholas J., Pierrat, Olivier, Brennan, Alfie, Roumeliotis, Theodoros I., Benstead-Hume, Graeme, Alexander, John, Muirhead, Gareth, Layzell, Scott, Lyu, Wenxin, Roulstone, Victoria, Allen, Mark, Baldock, Holly, Legrand, Arnaud, Gabel, Florian, Serrano-Aparicio, Natalia, Starling, Chris, Guo, Hongyan, Upton, Jason, Gyrd-Hansen, Mads, MacFarlane, Marion, Seddon, Benedict, Raynaud, Florence, Roxanis, Ioannis, Harrington, Kevin, Haider, Syed, Choudhary, Jyoti S., Hoelder, Swen, Tenev, Tencho, Meier, Pascal

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The Zds proteins control entry into mitosis and target protein phosphatase 2A to the Cdc25 phosphatase von Wicky, Sidonie, Tjandra, Hendri, Schieltz, David, Yates, 3rd, John, Kellogg, Douglas R

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Ubiquitin-mediated regulation of RIPK1 kinase activity independent of IKK and MK2 von Annibaldi, Alessandro, John, Sidonie Wicky, Vanden Berghe, Tom, Swatek, Kirby N, Ruan, Jianbin, Liccardi, Gianmaria, Bianchi, Katiuscia, Elliott, Paul R, Choi, Sze Men, Van Coillie, Samya, Bertin, John, Wu, Hao, Komander, David, Vandenabeele, Peter, Silke, John, Meier, Pascal

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Mind bomb regulates cell death during TNF signaling by suppressing RIPK1's cytotoxic potential von Feltham, Rebecca, Jamal, Kunzah, Tenev, Tencho, Liccardi, Gianmaria, Jaco, Isabel, Domingues, Celia Monteiro, Morris, Otto, John, Sidonie Wicky, Annibaldi, Alessandro, Widya, Marcella, Kearney, Conor J, Clancy, Danielle, Elliott, Paul R, Glatter, Timo, Qiao, Qi, Thompson, Andrew J, Nesvizhskii, Alexey, Schmidt, Alexander, Komander, David, Wu, Hao, Martin, Seamus, Meier, Pascal

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Sjl2p is specifically involved in early steps of endocytosis intimately linked to actin dynamics via the Ark1p/Prk1p kinases von Böttcher, Claudia, Wicky, Sidonie, Schwarz, Heinz, Singer-Krüger, Birgit

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Bsp1p/Ypr171p is an adapter that directly links some synaptojanin family members to the cortical actin cytoskeleton in yeast von Wicky, Sidonie, Frischmuth, Sabine, Singer-Krüger, Birgit

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A RIPK1-specific PROTAC degrader achieves potent antitumour activity by enhancing immunogenic cell death. Mannion et al von Mannion, Jonathan, Gifford, Valentina, Bellenie, Benjamin, Fernando, Winnie, Ramos Garcia, Laura, Wilson, Rebecca, Wicky John, Sidonie, Udainiya, Savita, Patin, Emmanuel, Tiu, Crescens, Smith, Angel, Goicoechea, Maria, Craxton, Andrew, Moraes de Vasconcelos, Nathalia, Guppy, Naomi, J Cheung, Kwai-Ming, J. Cundy, Nicholas, Pierrat, Olivier, Brennan, Alfie, I. Roumeliotis, Theodoros, Bensead-Hume, Graeme, Alexander, John, Muirhead, Gareth, Layzell, Scott, Lyu, Wenxin, Roulstone, Victoria, Allen, Mark, Balldock, Holly, Legrand, Arnaud, Gabel, Florian, Serrano-Aparicio, Natalia, Starling, Chris, Guo, Hongyan, Upton, Jason, Gyrd-Hansen, Mads, MacFarlane, Marion, Seddon, Benedict, Raynaud, Florence, Roxanis, Ioannis, Harrington, Kevin, Haider, Syed, S. Choudhary, Jyoti, Hoelder, Swen, Tenev, Tencho, Meier, Pascal

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A RIPK1-specific PROTAC degrader achieves potent antitumour activity by enhancing immunogenic cell death. Mannion et al von Mannion, Jonathan, Gifford, Valentina, Bellenie, Benjamin, Fernando, Winnie, Ramos Garcia, Laura, Wilson, Rebecca, Wicky John, Sidonie, Udainiya, Savita, Patin, Emmanuel, Tiu, Crescens, Smith, Angel, Goicoechea, Maria, Craxton, Andrew, Moraes de Vasconcelos, Nathalia, Guppy, Naomi, J Cheung, Kwai-Ming, J. Cundy, Nicholas, Pierrat, Olivier, Brennan, Alfie, I. Roumeliotis, Theodoros, Bensead-Hume, Graeme, Alexander, John, Muirhead, Gareth, Layzell, Scott, Lyu, Wenxin, Roulstone, Victoria, Allen, Mark, Balldock, Holly, Legrand, Arnaud, Gabel, Florian, Serrano-Aparicio, Natalia, Starling, Chris, Guo, Hongyan, Upton, Jason, Gyrd-Hansen, Mads, MacFarlane, Marion, Seddon, Benedict, Raynaud, Florence, Roxanis, Ioannis, Harrington, Kevin, Haider, Syed, S. Choudhary, Jyoti, Hoelder, Swen, Tenev, Tencho, Meier, Pascal

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Ubiquitin-mediated regulation of RIPK1 kinase activity, independent of IKK and MK2. Annibaldi et al von Annibaldi, Alessandro

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Characterization of the yeast proteins Neo1p and Sjl2p, two highly conserved regulators of phospholipid composition within endosomal membranes

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MK2 phosphorylates RIPK1 to prevent TNF induced cell death. Jaco et al von Meier, Pascal

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Mind bomb regulates cell death during TNF signaling by suppressing RIPK1’s cytotoxic potential von Feltham, Rebecca

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