Biochemical evidence for an alternate pathway in N-linked glycoprotein biosynthesis von Larkin, Angelyn, Chang, Michelle M, Whitworth, Garrett E, Imperiali, Barbara

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Differential Recognition and Hydrolysis of Host Carbohydrate Antigens by Streptococcus pneumoniae Family 98 Glycoside Hydrolases von Higgins, Melanie A., Whitworth, Garrett E., El Warry, Nahida, Randriantsoa, Mialy, Samain, Eric, Burke, Robert D., Vocadlo, David J., Boraston, Alisdair B.

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A potent mechanism-inspired O-GlcNAcase inhibitor that blocks phosphorylation of tau in vivo von Vocadlo, David J, Yuzwa, Scott A, Macauley, Matthew S, Heinonen, Julia E, Shan, Xiaoyang, Dennis, Rebecca J, He, Yuan, Whitworth, Garrett E, Stubbs, Keith A, McEachern, Ernest J, Davies, Gideon J

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Structural snapshots of the reaction coordinate for O-GlcNAc transferase von Lazarus, Michael B, Jiang, Jiaoyang, Gloster, Tracey M, Zandberg, Wesley F, Whitworth, Garrett E, Vocadlo, David J, Walker, Suzanne

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Selective biochemical labeling of Campylobacter jejuni cell-surface glycoconjugates von Whitworth, Garrett E, Imperiali, Barbara

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O-GlcNAcase uses substrate-assisted catalysis: kinetic analysis and development of highly selective mechanism-inspired inhibitors von Macauley, Matthew S, Whitworth, Garrett E, Debowski, Aleksandra W, Chin, Danielle, Vocadlo, David J

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Analysis of a New Family of Widely Distributed Metal-independent α-Mannosidases Provides Unique Insight into the Processing of N-Linked Glycans von Gregg, Katie J., Zandberg, Wesley F., Hehemann, Jan-Hendrik, Whitworth, Garrett E., Deng, Lehua, Vocadlo, David J., Boraston, Alisdair B.

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Analysis of PUGNAc and NAG-thiazoline as Transition State Analogues for Human O-GlcNAcase:  Mechanistic and Structural Insights into Inhibitor Selectivity and Transition State Pois... von Whitworth, Garrett E, Macauley, Matthew S, Stubbs, Keith A, Dennis, Rebecca J, Taylor, Edward J, Davies, Gideon J, Greig, Ian R, Vocadlo, David J

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The Development of Selective Inhibitors of NagZ: Increased Susceptibility of Gram-Negative Bacteria to β-Lactams von Stubbs, Keith A., Bacik, John-Paul, Perley-Robertson, G. Evan, Whitworth, Garrett E., Gloster, Tracey M., Vocadlo, David J., Mark, Brian L.

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Mammalian Notch is modified by d-Xyl- alpha 1-3-d-Xyl- alpha 1-3-d-Glc- beta 1-O-Ser: Implementation of a method to study O-glucosylation von Whitworth, Garrett E, Zandberg, Wesley F, Clark, Thomas, Vocadlo, David J

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O-GlcNAcase Uses Substrate-assisted Catalysis von Macauley, Matthew S., Whitworth, Garrett E., Debowski, Aleksandra W., Chin, Danielle, Vocadlo, David J.

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Metabolism of vertebrate amino sugars with N-glycolyl groups: intracellular β-O-linked N-glycolylglucosamine (GlcNGc), UDP-GlcNGc, and the biochemical and structural rationale for... von Macauley, Matthew S, Chan, Jefferson, Zandberg, Wesley F, He, Yuan, Whitworth, Garrett E, Stubbs, Keith A, Yuzwa, Scott A, Bennet, Andrew J, Varki, Ajit, Davies, Gideon J, Vocadlo, David J

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Molecular Basis of 1,6-Anhydro Bond Cleavage and Phosphoryl Transfer by Pseudomonas aeruginosa 1,6-Anhydro-N-acetylmuramic Acid Kinase von Bacik, John-Paul, Whitworth, Garrett E., Stubbs, Keith A., Yadav, Anuj K., Martin, Dylan R., Bailey-Elkin, Ben A., Vocadlo, David J., Mark, Brian L.

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Active Site Plasticity within the Glycoside Hydrolase NagZ Underlies a Dynamic Mechanism of Substrate Distortion von Bacik, John-Paul, Whitworth, Garrett E., Stubbs, Keith A., Vocadlo, David J., Mark, Brian L.

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Mammalian Notch is modified by D-Xyl-α1-3-D-Xyl-α1-3-D-Glc-β1-O-Ser: Implementation of a method to study O-glucosylation von Whitworth, Garrett E, Zandberg, Wesley F, Clark, Thomas, Vocadlo, David J

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The Development of Selective Inhibitors of NagZ: Increased Susceptibility of Gram-Negative Bacteria to [beta]-Lactams von Stubbs, Keith A, Bacik, John-Paul, Perley-Robertson, G Evan, Whitworth, Garrett E, Gloster, Tracey M, Vocadlo, David J, Mark, Brian L

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Structural snapshots of the reaction coordinate for O-GlcNAc transferase von Lazarus, Michael B, Jiang, Jiaoyang, Gloster, Tracey M, Zandberg, Wesley F, Whitworth, Garrett E, Vocadlo, David J, Walker, Suzanne

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Metabolism of Vertebrate Amino Sugars with N-Glycolyl Groups von Macauley, Matthew S., Chan, Jefferson, Zandberg, Wesley F., He, Yuan, Whitworth, Garrett E., Stubbs, Keith A., Yuzwa, Scott A., Bennet, Andrew J., Varki, Ajit, Davies, Gideon J., Vocadlo, David J.

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Mammalian Notch is modified by D-Xyl-alpha1-3-D-Xyl-alpha1-3-D-Glc-beta1-O-Ser: implementation of a method to study O-glucosylation von Whitworth, Garrett E, Zandberg, Wesley F, Clark, Thomas, Vocadlo, David J

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Classification of variants of reduced penetrance in high-penetrance cancer susceptibility genes: Framework for genetics clinicians and clinical scientists by CanVIG-UK (Cancer Vari... von Allen, Sophie, Durkie, Miranda, Burghel, George J., Palmer-Smith, Sheila, McDevitt, Trudi, Garrett, A., Loong, L., Torr, B., Allen, S., Berry, I.R., Eccles, D.M., Tischkowitz, M., Evans, D.G., Lalloo, F., Kumar, A., Ross, A., Hogg, A.C., McIldowie, B., Olimpio, C., Clabby, C., Byrne, C., Moore, D., Donnelly, D., Atkinson, E., Johnston, E., Powell, H., Hoyle, J., Murray, J., Callaway, J., Murphy, K., Cadoo, K., Brown, K., Reay, K., McKay Bounford, K., Bradshaw, K., Reed, L., Hawkes, L., Kiely, L., Side, L., Shanmugasundaram, M., Duff, M., Ahmed, M., O'Brien, C., Middleton, O., Logan, P., Tredwell, R., Harrison, R., Nyanhete, R., Davidson, R., Butler, S., Dell, S., Greville-Heygate, S., Tennant, S., McVeigh, T., Clowes, V., Kemp, Z., Joyce, C., Timbs, A., Husher, C., Reay, D., Harper, J., Linton-Willoughby, T., Watt, C., Mitchell, R., Nickless, G., McCarthy, C., Botosneanu, S., Sherlaw, C., Forde, C., Petley, E., Braham, R., Hanington, L., Irving, R., Gabriel, J., Chiecchio, L., Cloke, V., Pleasance, B., Whitehouse, H., Sau, C., Massey, H., Gillespie, K., Alder, A., Cassidy, C., Orfali, N., Luharia, A., Andreou, A., Edis, M., Callard, A., Ostrowski, P., Freestone, L., Whitworth, A., Mutch, S., Begum, R., Smith, C., Taylor, S., McSorley, L., Alexopoulos, P., Moore, R., Kosicka-Slawinska, M., Ali, F.

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