Apoptosis is Induced by β-Amyloid in Cultured Central Nervous System Neurons von Loo, Deryk T., Copani, Agata, Pike, Christian J., Whittemore, Edward R., Walencewicz, Andrea J., Cotman, Carl W.

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A detailed analysis of hydrogen peroxide-induced cell death in primary neuronal culture von Whittemore, E.R., Loo, D.T., Watt, J.A., Cotmans, C.W.

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Subtype-selective inhibition of N-methyl-D-aspartate receptors by haloperidol von Ilyin, V I, Whittemore, E R, Guastella, J, Weber, E, Woodward, R M

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Exposure to hydrogen peroxide induces cell death via apoptosis in cultured rat cortical neurons von Whittemore, Edward R, Loo, Deryk T, Cotman, Carl W

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Subtype-Selective N-Methyl-d-aspartate Receptor Antagonists:  Benzimidazalone and Hydantoin as Phenol Replacements von Schelkun, Robert M, Yuen, Po-wai, Serpa, Kevin, Meltzer, Leonard T, Wise, Lawrence D, Whittemore, Edward R, Woodward, Richard M

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Structure−Activity Relationship of N-(Phenylalkyl)cinnamides as Novel NR2B Subtype-Selective NMDA Receptor Antagonists von Tamiz, Amir P, Cai, Sui Xiong, Zhou, Zhang-Lin, Yuen, Po-Wai, Schelkun, Robert M, Whittemore, Edward R, Weber, Eckard, Woodward, Richard M, Keana, John F. W

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Synthesis of N-Substituted 4-(4-Hydroxyphenyl)piperidines, 4-(4-Hydroxybenzyl)piperidines, and (±)-3-(4-Hydroxyphenyl)pyrrolidines:  Selective Antagonists at the 1a/2B NMDA Recepto... von Guzikowski, Anthony P, Tamiz, Amir P, Acosta-Burruel, Manuel, Hong-Bae, Soo, Cai, Sui Xiong, Hawkinson, Jon E, Keana, John F. W, Kesten, Suzanne R, Shipp, Christina T, Tran, Minhtam, Whittemore, Edward R, Woodward, Richard M, Wright, Jon L, Zhou, Zhang-Lin

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Subtype-Selective N-Methyl-d-Aspartate Receptor Antagonists:  Synthesis and Biological Evaluation of 1-(Heteroarylalkynyl)-4-benzylpiperidines von Wright, Jon L, Gregory, Tracy F, Kesten, Suzanne R, Boxer, Peter A, Serpa, Kevin A, Meltzer, Leonard T, Wise, Lawrence D, Espitia, Stephen A, Konkoy, Christopher S, Whittemore, Edward R, Woodward, Richard M

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Structure−Activity Relationships for a Series of Bis(phenylalkyl)amines:  Potent Subtype-Selective Inhibitors of N-Methyl-d-aspartate Receptors von Tamiz, Amir P, Whittemore, Edward R, Zhou, Zhang-Lin, Huang, Jin-Cheng, Drewe, John A, Chen, Jie-Cheng, Cai, Sui-Xiong, Weber, Eckard, Woodward, Richard M, Keana, John F. W

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Heparan sulfate and chondroitin sulfate glycosaminoglycan attenuate β-amyloid(25–35) induced neurodegeneration in cultured hippocampal neurons von Woods, Alisa G., Cribbs, David H., Whittemore, Edward R., Cotman, Carl W.

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Subtype-selective antagonism of NMDA receptors by nylidrin von Whittemore, E.R, Ilyin, V.I, Konkoy, C.S, Woodward, R.M

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Synthesis and Structure−Activity Relationships of 1,2,3,4-Tetrahydroquinoline-2,3,4-trione 3-Oximes:  Novel and Highly Potent Antagonists for NMDA Receptor Glycine Site von Cai, Sui Xiong, Zhou, Zhang-Lin, Huang, Jin-Cheng, Whittemore, Edward R, Egbuwoku, Zizi O, Lü, Yixin, Hawkinson, Jon E, Woodward, Richard M, Weber, Eckard, Keana, John F. W

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Synthesis of Racemic 6,7,8,9-Tetrahydro-3-hydroxy-1H-1-benzazepine-2,5-diones as Antagonists of N-Methyl-d-aspartate (NMDA) and α-Amino-3-hydroxy-5-methylisoxazole-4-propionic Acid... von Guzikowski, Anthony P, Whittemore, Edward R, Woodward, Richard M, Weber, Eckard, Keana, John F. W

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4-Hydroxy-1-[2-(4-hydroxyphenoxy)ethyl]-4-(4-methylbenzyl)piperidine:  A Novel, Potent, and Selective NR1/2B NMDA Receptor Antagonist von Zhou, Zhang-Lin, Cai, Sui Xiong, Whittemore, Edward R, Konkoy, Christopher S, Espitia, Stephen A, Tran, Minhtam, Rock, David M, Coughenour, Linda L, Hawkinson, Jon E, Boxer, Peter A, Bigge, Christopher F, Wise, Lawrence D, Weber, Eckard, Woodward, Richard M, Keana, John F. W

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Possible Role of Apoptosis in Alzheimer's Disease von COTMAN, CARL W., WHITTEMORE, EDWARD R., WATT, JOHN A., ANDERSON, AILEEN J., LOO, DERYK T.

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An Explanation for the Purported Excitation of Piriform Cortical Neurons by N-acetyl-L-aspartyl-L-glutamic Acid (NAAG) von Whittemore, Edward R., Koerner, James F.

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Differential regulation by β-amyloid peptides of intracellular free Ca2+ concentration in cultured rat microglia von KOROTZER, A. R, WHITTEMORE, E. R, COTMAN, C. W

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Carbachol increases intracellular free calcium in cultured rat microglia von Whittemore, Edward R., Korotzer, Andrew R., Etebari, Amir, Cotman, Carl W.

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Subtype-Selective N-Methyl-d-aspartate Receptor Antagonists:  Synthesis and Biological Evaluation of 1-(Arylalkynyl)-4-benzylpiperidines von Wright, Jon L, Gregory, Tracy F, Bigge, Christopher F, Boxer, Peter A, Serpa, Kevin, Meltzer, Leonard T, Wise, Lawrence D, Cai, Sui Xiong, Hawkinson, Jon E, Konkoy, Christopher S, Whittemore, Edward R, Woodward, Richard M, Zhou, Zhang-Lin

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Structure−Activity Relationships of 4-Hydroxy-3-nitroquinolin-2(1H)-ones as Novel Antagonists at the Glycine Site of N-Methyl-d-aspartate Receptors von Cai, Sui Xiong, Zhou, Zhang-Lin, Huang, Jin-Cheng, Whittemore, Edward R, Egbuwoku, Zizi O, Hawkinson, Jon E, Woodward, Richard M, Weber, Eckard, Keana, John F. W

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