Protective hinge in insulin opens to enable its receptor engagement von Menting, John G, Yang, Yanwu, Chan, Shu Jin, Phillips, Nelson B, Smith, Brian J, Whittaker, Jonathan, Wickramasinghe, Nalinda P, Whittaker, Linda J, Pandyarajan, Vijay, Wan, Zhu-li, Yadav, Satya P, Carroll, Julie M, Strokes, Natalie, Roberts, Jr, Charles T, Ismail-Beigi, Faramarz, Milewski, Wieslawa, Steiner, Donald F, Chauhan, Virander S, Ward, Colin W, Weiss, Michael A, Lawrence, Michael C

Volltext

α-Helical element at the hormone-binding surface of the insulin receptor functions as a signaling element to activate its tyrosine kinase von Whittaker, Jonathan, Whittaker, Linda J, Roberts, Charles T, Phillips, Nelson B, Ismail-Beigi, Faramarz, Lawrence, Michael C, Weiss, Michael A

Volltext

Comparative Properties of Insulin-like Growth Factor 1 (IGF-1) and [Gly7D-Ala]IGF-1 Prepared by Total Chemical Synthesis von Sohma, Youhei, Pentelute, Brad L, Whittaker, Jonathan, Hua, Qin-xin, Whittaker, Linda J, Weiss, Michael A, Kent, Stephen B.H

Volltext

How insulin engages its primary binding site on the insulin receptor von Menting, John G., Whittaker, Jonathan, Margetts, Mai B., Whittaker, Linda J., Kong, Geoffrey K.-W., Smith, Brian J., Watson, Christopher J., Žáková, Lenka, Kletvíková, Emília, Jiráček, Jiří, Chan, Shu Jin, Steiner, Donald F., Dodson, Guy G., Brzozowski, Andrzej M., Weiss, Michael A., Ward, Colin W., Lawrence, Michael C.

Volltext

Contribution of Residue B5 to the Folding and Function of Insulin and IGF-I: CONSTRAINTS AND FINE-TUNING IN THE EVOLUTION OF A PROTEIN FAMILY von Sohma, Youhei, Hua, Qing-xin, Liu, Ming, Phillips, Nelson B, Hu, Shi-Quan, Whittaker, Jonathan, Whittaker, Linda J, Ng, Aubree, Roberts, Charles T. Jr, Arvan, Peter, Kent, Stephen B.H, Weiss, Michael A

Volltext

Alanine Scanning Mutagenesis of a Type 1 Insulin-like Growth Factor Receptor Ligand Binding Site von Whittaker, Jonathan, Groth, Andreas V., Mynarcik, Dennis C., Pluzek, Lene, Gadsbøll, Vibeke L., Whittaker, Linda J.

Volltext

Contribution of Residue B5 to the Folding and Function of Insulin and IGF-I von Sohma, Youhei, Hua, Qing-xin, Liu, Ming, Phillips, Nelson B., Hu, Shi-Quan, Whittaker, Jonathan, Whittaker, Linda J., Ng, Aubree, Roberts, Charles T., Arvan, Peter, Kent, Stephen B.H., Weiss, Michael A.

Volltext

[alpha]-Helical element at the hormone-binding surface of the insulin receptor functions as a signaling element to activate its tyrosine kinase von Whittaker, Jonathan, Whittaker, Linda J, Roberts, Charles T, Phillips, Nelson B, Ismail-Beigi, Faramarz, Lawrence, Michael C, Weiss, Michael A

Volltext

Comparative Properties of Insulin-like Growth Factor 1 (IGF-1) and [Gly7D-Ala]IGF-1 Prepared by Total Chemical Synthesis von Sohma, Youhei, Pentelute, Brad L., Whittaker, Jonathan, Hua, Qin-xin, Whittaker, Linda J., Weiss, Michael A., Kent, Stephen B. H.

Volltext

Protective hinge in insulin opens to enable its receptor engagement von Menting, John G., Yang, Yanwu, Chan, Shu Jin, Phillips, Nelson B., Smith, Brian J., Whittaker, Jonathan, Wickramasinghe, Nalinda P., Whittaker, Linda J., Pandyarajan, Vijay, Wan, Zhu-li, Yadav, Satya P., Carroll, Julie M., Strokes, Natalie, Roberts, Charles T., Ismail-Beigi, Faramarz, Milewski, Wieslawa, Steiner, Donald F., Chauhan, Virander S., Ward, Colin W., Weiss, Michael A., Lawrence, Michael C.

Volltext

CARBOXY-TERMINAL ELEMENTS OF C-MYB NEGATIVELY REGULATE TRANSCRIPTIONAL ACTIVATION IN CIS AND IN TRANS von DUBENDORFF, JW, WHITTAKER, LJ, ELTMAN, JT, LIPSICK, JS

Volltext

HLA-DQA102:01 Is a Major Risk Factor for Lapatinib-Induced Hepatotoxicity in Women With Advanced Breast Cancer von SPRAGGS, Colin F, BUDDE, Laura R, CARDON, Lon R, BRILEY, Linda P, NAN BING, COX, Charles J, KING, Karen S, WHITTAKER, John C, MOOSER, Vincent E, PRESTON, Alaknanda J, STEIN, Steven H

Volltext

Health-related Outcomes after a Youth Sport–related Knee Injury von WHITTAKER, JACKIE L, TOOMEY, CLODAGH M, NETTEL-AGUIRRE, ALBERTO, JAREMKO, JACOB L, DOYLE-BAKER, PATRICIA K, WOODHOUSE, LINDA J, EMERY, CAROLYN A

Volltext

Causal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts von Vimaleswaran, Karani S, Berry, Diane J, Lu, Chen, Tikkanen, Emmi, Pilz, Stefan, Hiraki, Linda T, Cooper, Jason D, Dastani, Zari, Li, Rui, Houston, Denise K, Wood, Andrew R, Michaëlsson, Karl, Vandenput, Liesbeth, Zgaga, Lina, Yerges-Armstrong, Laura M, McCarthy, Mark I, Dupuis, Josée, Kaakinen, Marika, Kleber, Marcus E, Jameson, Karen, Arden, Nigel, Raitakari, Olli, Viikari, Jorma, Lohman, Kurt K, Ferrucci, Luigi, Melhus, Håkan, Ingelsson, Erik, Byberg, Liisa, Lind, Lars, Lorentzon, Mattias, Salomaa, Veikko, Campbell, Harry, Dunlop, Malcolm, Mitchell, Braxton D, Herzig, Karl-Heinz, Pouta, Anneli, Hartikainen, Anna-Liisa, Streeten, Elizabeth A, Theodoratou, Evropi, Jula, Antti, Wareham, Nicholas J, Ohlsson, Claes, Frayling, Timothy M, Kritchevsky, Stephen B, Spector, Timothy D, Richards, J Brent, Lehtimäki, Terho, Ouwehand, Willem H, Kraft, Peter, Cooper, Cyrus, März, Winfried, Power, Chris, Loos, Ruth J F, Wang, Thomas J, Järvelin, Marjo-Riitta, Whittaker, John C, Hingorani, Aroon D, Hyppönen, Elina

Volltext

Sticking to It: A Scoping Review of Adherence to Exercise Therapy Interventions in Children and Adolescents With Musculoskeletal Conditions von Holt, Christopher J., Mckay, Carly D., Truong, Linda K., Le, Christina Y., Gross, Douglas P., Whittaker, Jackie L.

Volltext

Treatment of Multisystem Inflammatory Syndrome in Children von McArdle, Andrew J, Vito, Ortensia, Patel, Harsita, Seaby, Eleanor G, Shah, Priyen, Wilson, Clare, Broderick, Claire, Nijman, Ruud, Tremoulet, Adriana H, Munblit, Daniel, Ulloa-Gutierrez, Rolando, Carter, Michael J, De, Tisham, Hoggart, Clive, Whittaker, Elizabeth, Herberg, Jethro A, Kaforou, Myrsini, Cunnington, Aubrey J, Levin, Michael

Volltext

Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility von Brown, Matthew A, Donnelly, Peter, Evans, David M, Spencer, Chris C A, Pointon, Jennifer J, Su, Zhan, Harvey, David, Kochan, Grazyna, Opperman, Udo, Dilthey, Alexander, Pirinen, Matti, Stone, Millicent A, Appleton, Louise, Moutsianis, Loukas, Leslie, Stephen, Wordsworth, Tom, Kenna, Tony J, Karaderi, Tugce, Thomas, Gethin P, Ward, Michael M, Weisman, Michael H, Farrar, Claire, Bradbury, Linda A, Danoy, Patrick, Inman, Robert D, Maksymowych, Walter, Gladman, Dafna, Rahman, Proton, Morgan, Ann, Marzo-Ortega, Helena, Bowness, Paul, Gaffney, Karl, Gaston, J S Hill, Smith, Malcolm, Bruges-Armas, Jacome, Couto, Ana-Rita, Sorrentino, Rosa, Paladini, Fabiana, Ferreira, Manuel A, Xu, Huji, Liu, Yu, Jiang, Lei, Lopez-Larrea, Carlos, Díaz-Peña, Roberto, López-Vázquez, Antonio, Zayats, Tetyana, Band, Gavin, Bellenguez, Céline, Blackburn, Hannah, Blackwell, Jenefer M, Bramon, Elvira, Bumpstead, Suzannah J, Casas, Juan P, Corvin, Aiden, Craddock, Nicholas, Deloukas, Panos, Dronov, Serge, Duncanson, Audrey, Edkins, Sarah, Freeman, Colin, Gillman, Matthew, Gray, Emma, Gwilliam, Rhian, Hammond, Naomi, Hunt, Sarah E, Jankowski, Janusz, Jayakumar, Alagurevathi, Langford, Cordelia, Liddle, Jennifer, Markus, Hugh S, Mathew, Christopher G, McCann, Owen T, McCarthy, Mark I, Palmer, Colin N A, Peltonen, Leena, Plomin, Robert, Potter, Simon C, Rautanen, Anna, Ravindrarajah, Radhi, Ricketts, Michelle, Samani, Nilesh, Sawcer, Stephen J, Strange, Amy, Trembath, Richard C, Viswanathan, Ananth C, Waller, Matthew, Weston, Paul, Whittaker, Pamela, Widaa, Sara, Wood, Nicholas W, McVean, Gilean, Reveille, John D, Wordsworth, B Paul

Volltext

Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci von Reveille, John D, Sims, Anne-Marie, Danoy, Patrick, Evans, David M, Leo, Paul, Pointon, Jennifer J, Jin, Rui, Zhou, Xiaodong, Bradbury, Linda A, Appleton, Louise H, Davis, John C, Diekman, Laura, Doan, Tracey, Dowling, Alison, Duan, Ran, Duncan, Emma L, Farrar, Claire, Hadler, Johanna, Harvey, David, Karaderi, Tugce, Mogg, Rebecca, Pomeroy, Emma, Pryce, Karena, Taylor, Jacqueline, Savage, Laurie, Deloukas, Panos, Kumanduri, Vasudev, Peltonen, Leena, Ring, Sue M, Whittaker, Pamela, Glazov, Evgeny, Thomas, Gethin P, Maksymowych, Walter P, Inman, Robert D, Ward, Michael M, Stone, Millicent A, Weisman, Michael H, Wordsworth, B Paul, Brown, Matthew A

Volltext

Characterization of the Functional Insulin Binding Epitopes of the Full-length Insulin Receptor von Whittaker, Jonathan, Whittaker, Linda

Volltext

Higher Fat Mass Is Associated With a History of Knee Injury in Youth Sport von Toomey, Clodagh M, Whittaker, Jackie L, Nettel-Aguirre, Alberto, Reimer, Raylene A, Woodhouse, Linda J, Ghali, Brianna, Doyle-Baker, Patricia K, Emery, Carolyn A

Volltext