Oxygenated Cyclopentenones via the Pauson-Khand Reaction of Silyl Enol Ether Substrates von Shaw, Paul, Hassell-Hart, Storm J, Douglas, Gayle E, Malcolm, Andrew G, Kennedy, Alan R, White, Gemma V, Paterson, Laura C, Kerr, William J

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Acetylation of the Catalytic Lysine Inhibits Kinase Activity in PI3Kδ von Fournier, Julie C. L, Evans, John P, Zappacosta, Francesca, Thomas, Daniel A, Patel, Vipulkumar K, White, Gemma V, Campos, Sebastien, Tomkinson, Nicholas C. O

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Kallikrein 5 inhibitors identified through structure based drug design in search for a treatment for Netherton Syndrome von White, Gemma V., Edgar, Emma V., Holmes, Duncan S., Lewell, Xiao Qing, Liddle, John, Polyakova, Oxana, Smith, Kathrine J., Thorpe, James H., Walker, Ann L., Wang, Yichen, Young, Robert J., Hovnanian, Alain

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Structure guided drug design to develop kallikrein 5 inhibitors to treat Netherton syndrome von Walker, Ann L., Bingham, Ryan P., Edgar, Emma V., Ferrie, Alan, Holmes, Duncan S., Liddle, John, Polyakova, Oxana, Rella, Monika, Smith, Kathrine J., Thorpe, James H., Wang, Yichen, White, Gemma V., Young, Robert J., Hovnanian, Alain

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Evaluation of a crystallographic surrogate for kallikrein 5 in the discovery of novel inhibitors for Netherton syndrome von Thorpe, James H., Edgar, Emma V., Smith, Kathrine J., Lewell, Xiao Q., Rella, Monika, White, Gemma V., Polyakova, Oxana, Nassau, Pamela, Walker, Ann L., Holmes, Duncan S., Pearce, Andrew C., Wang, Yichen, Liddle, John, Hovnanian, Alain

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Synthesis and evaluation of novel α-amino cyclic boronates as inhibitors of HCV NS3 protease von Li, Xianfeng, Zhang, Yong-Kang, Liu, Yang, Ding, Charles Z., Li, Qun, Zhou, Yasheen, Plattner, Jacob J., Baker, Stephen J., Qian, Xuelei, Fan, Dazhong, Liao, Liang, Ni, Zhi-Jie, White, Gemma V., Mordaunt, Jackie E., Lazarides, Linos X., Slater, Martin J., Jarvest, Richard L., Thommes, Pia, Ellis, Malcolm, Edge, Colin M., Hubbard, Julia A., Somers, Don, Rowland, Paul, Nassau, Pamela, McDowell, Bill, Skarzynski, Tadeusz J., Kazmierski, Wieslaw M., Grimes, Richard M., Wright, Lois L., Smith, Gary K., Zou, Wuxin, Wright, Jon, Pennicott, Lewis E.

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Discovery and Lead-Optimization of 4,5-Dihydropyrazoles as Mono-Kinase Selective, Orally Bioavailable and Efficacious Inhibitors of Receptor Interacting Protein 1 (RIP1) Kinase von Harris, Philip A, Faucher, Nicolas, George, Nicolas, Eidam, Patrick M, King, Bryan W, White, Gemma V, Anderson, Niall A, Bandyopadhyay, Deepak, Beal, Allison M, Beneton, Veronique, Berger, Scott B, Campobasso, Nino, Campos, Sebastien, Capriotti, Carol A, Cox, Julie A, Daugan, Alain, Donche, Frederic, Fouchet, Marie-Hélène, Finger, Joshua N, Geddes, Brad, Gough, Peter J, Grondin, Pascal, Hoffman, Bonnie L, Hoffman, Sandra J, Hutchinson, Susan E, Jeong, Jae U, Jigorel, Emilie, Lamoureux, Pauline, Leister, Lara K, Lich, John D, Mahajan, Mukesh K, Meslamani, Jamel, Mosley, Julie E, Nagilla, Rakesh, Nassau, Pamela M, Ng, Sze-Ling, Ouellette, Michael T, Pasikanti, Kishore K, Potvain, Florent, Reilly, Michael A, Rivera, Elizabeth J, Sautet, Stéphane, Schaeffer, Michelle C, Sehon, Clark A, Sun, Helen, Thorpe, James H, Totoritis, Rachel D, Ward, Paris, Wellaway, Natalie, Wisnoski, David D, Woolven, James M, Bertin, John, Marquis, Robert W

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4-Acyl-1-(4-aminoalkoxyphenyl)-2-ketopiperazines as a Novel Class of Non-Brain-Penetrant Histamine H3 Receptor Antagonists von Procopiou, Panayiotis A, Ancliff, Rachael A, Bamford, Mark J, Browning, Christopher, Connor, Helen, Davies, Susannah, Fogden, Yvonne C, Hodgson, Simon T, Holmes, Duncan S, Looker, Brian E, Morriss, Karen M. L, Parr, Christopher A, Pickup, Elizabeth A, Sehmi, Sanjeet S, White, Gemma V, Watts, Clarissa J, Wilson, David M, Woodrow, Michael D

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4-Acyl-1-(4-aminoalkoxyphenyl)-2-ketopiperazines as a Novel Class of Non-Brain-Penetrant Histamine H 3 Receptor Antagonists von Procopiou, Panayiotis A., Ancliff, Rachael A., Bamford, Mark J., Browning, Christopher, Connor, Helen, Davies, Susannah, Fogden, Yvonne C., Hodgson, Simon T., Holmes, Duncan S., Looker, Brian E., Morriss, Karen M. L., Parr, Christopher A., Pickup, Elizabeth A., Sehmi, Sanjeet S., White, Gemma V., Watts, Clarissa J., Wilson, David M., Woodrow, Michael D.

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Prognoses and improvement for head and neck cancers diagnosed in Europe in early 2000s: The EUROCARE-5 population-based study von Gatta, Gemma, Botta, Laura, Sánchez, María José, Anderson, Lesley Ann, Pierannunzio, Daniela, Licitra, Lisa

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Prehospital transdermal glyceryl trinitrate in patients with ultra-acute presumed stroke (RIGHT-2): an ambulance-based, randomised, sham-controlled, blinded, phase 3 trial von Bath, Philip M, Cala, Lesley, Dixon, Mark, Mair, Grant, Potter, John, Roffe, Christine, Sandset, Else C, Sanossian, Nerses, Venables, Graham, Sprigg, Nikola, Amarenco, Pierre, Walker, Gemma, Gregory, Hayley, Smithson, Jennifer, Keeling, Joanne, Frowd, Nadia, Law, Zhe Kang, Payne, T, Spaight, R, Spaight, A, Whileman, A, Patel, C, Khan, S, Perkin, L, Arif, S, Sunman, W, Buck, A, Richardson, C, Constantin, C, Markova, S, Hedstrom, A, Keane, S, McKenzie, H, Mellows, K, Wyllie, H, Goffin, K, Ravenhill, G, Ford, L, Davison, W, Ho, C, McKenzie, E, Sylvester, N, Skene, I, Cuenoud, L, Daboo, P, Watchurst, C, Obarey, S, Pocock, H, Robinson, M, Oborn, M, Obeid, M, Whiting, R, Gagg, J, Hussain, M, Bagnall, C, Harrington, F, Nisbett, T, Jennings, G, Shaw, L, Worner, R, Saulat, A, Garfield-Smith, J, Haley, M, Rashed, K, Tanate, A, Wood, D, Matthews, L, Rees, N, Convery, C, Dixon, M, Davies, C, Chandler, A, Andrews, K, Horwood, P, Boldy, R, Jenkins, C, Price, F, Willberry, A, Alipio, F, Hiden, J, Varquez, R, Epstein, E, Hurdowar, S, Bellfield, R, Nair, A, Wilson, A, Gomes, P, Bwalya, A, Gillespie, A, Naylor, C, Clarkson, E, Finch, L, Datta, P, Needle, A, Walker, R, Murray, V, Ali, A, Kamara, C, Doyle, C, Willcoxson, P

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Effects of oral anticoagulation for atrial fibrillation after spontaneous intracranial haemorrhage in the UK: a randomised, open-label, assessor-masked, pilot-phase, non-inferiorit... von Lewis, Steff, Norrie, John, Armitage, Jane, Lowe, Gordon, Dinsmore, Lynn, Fraser, Ruth, Rees, Jessica, Hall, Peter, Burgess, Seona, Taylor, Pat, Fethers, Nicholas, Choulerton, James, Lucas, Suzanne, Hierons, Sarah, Lindert, Ralf, Bathula, Raj, Chhabra, Swati, Smith, Gemma, Rogers, Gill, Wilkinson, Ami, Abraham, Annie, Ramiz, Ridha, Shaw, Ryan, Stafford, Sam, Knibbs, Lucy, Schwarz, Stefan, Moseley, Sally, Rashed, Khalid, Board, Sarah, Perry, Jess, Menon, Nisha, Weir, Nic, Yates, Hannah, Smith, Simon, Evans, Sue, Baldwin, Laura, Hammond, Sarah, Bowring, Angela, Peachey, Tracey, Haines, Fiona, Licenik, Radim, Ashton, Amy, Feerick, Shez, Francia, Nina, Banaras, Azra, Epstein, Daniel, Humphries, Fiona, Papavasileiou, Vasileios, Ahmed, Rowshanara, Elliot, Jennifer, Hatherley, Kim, Schulz, Ursula, Bhupathiraju, Neelima, Stevens, Angie, Willberry, Angela, Mallon, Louise, Duffy, John, Fitton, Carolyn, Trippier, Sarah, Rita, Ghatala, Zhang, Liqun, Clarke, Brian, Al-Hussayni, Samer, Young, Andrew, McAuley, Sean, Smith, Andrew, Atkinson, Beth, Cameron, Eleanor, Concannon, Dónal, Dutta, Dipankar, Jenkinson, Damian, Bokhari, Maria, McClelland, Beverley, James, Ali, Coutts, Abbie, Webber, Sue, Chapman, Lianne, Mukherjee, Indranil, Wilcox, Rebecca, Jackson, Linda, Francis, Jobbin, McGee, Joanne, Finlay, Sarah, King, Sam, Choudhary, Sumita, Saulat, Afaq, Fitzell, Pauline, Horan, Kathleen, Manyoni, Catherine, Griffin, Hannah, Barry, Adrian, Remegoso, Alda, Finney, Kay, Irvine, Janice, Guzmangutierrez, German, Bellfield, Ruth, Ahmed, Shakeel, Sultan, Sulaiman, Wright, Fiona, Quinn, Terry

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A Turing Test for Molecular Generators von Bush, Jacob T, Pogany, Peter, Pickett, Stephen D, Barker, Mike, Baxter, Andrew, Campos, Sebastien, Cooper, Anthony W. J, Hirst, David, Inglis, Graham, Nadin, Alan, Patel, Vipulkumar K, Poole, Darren, Pritchard, John, Washio, Yoshiaki, White, Gemma, Green, Darren V. S

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Early Intervention in Patients With Asymptomatic Severe Aortic Stenosis and Myocardial Fibrosis: The EVOLVED Randomized Clinical Trial von Loganath, Krithika, Craig, Neil J, Everett, Russell J, Bing, Rong, Tsampasian, Vasiliki, Molek, Patrycja, Botezatu, Simona, Aslam, Saadia, Lewis, Steff, Graham, Catriona, White, Audrey C, MacGillivray, Tom, Tuck, Christopher E, Rayson, Phillip, Cranley, Denise, Irvine, Sian, Armstrong, Ruth, Milne, Lynsey, Chin, Calvin W. L, Hillis, Graham S, Fairbairn, Timothy, Greenwood, John P, Steeds, Richard, Leslie, Stephen J, Lang, Chim C, Bucciarelli-Ducci, Chiara, Joshi, Nikhil V, Kunadian, Vijay, Vassiliou, Vassilios S, Dungu, Jason N, Hothi, Sandeep S, Boon, Nicholas, Prasad, Sanjay K, Keenan, Niall G, Dawson, Dana, Treibel, Thomas A, Motwani, Mani, Miller, Christopher A, Mills, Nicholas L, Rajani, Ronak, Ripley, David P, McCann, Gerry P, Prendergast, Bernard, Singh, Anvesha, Newby, David E, Dweck, Marc R

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Integrated Guidance for Enhancing the Care of Familial Hypercholesterolaemia in Australia von Watts, Gerald F., Sullivan, David R., Hare, David L., Kostner, Karam M., Horton, Ari E., Bell, Damon A., Brett, Tom, Trent, Ronald J., Poplawski, Nicola K., Martin, Andrew C., Srinivasan, Shubha, Justo, Robert N., Chow, Clara K., Pang, Jing, Ademi, Zanfina, Ardill, Justin J., Barnett, Wendy, Bates, Timothy R., Beilin, Lawrence J., Bishop, Warrick, Black, J. Andrew, Brett, Peter, Brown, Alex, Burnett, John R., Bursill, Christina A., Colley, Alison, Clifton, Peter M., Ekinci, Elif I., Elias, Luke, Figtree, Gemma A., Forge, Brett H., Garton-Smith, Jacquie, Graham, Dorothy F., Hamilton-Craig, Ian, Hamilton-Craig, Christian R., Heal, Clare, Hespe, Charlotte M., Hooper, Amanda J., Howes, Laurence G., Ingles, Jodie, Irvin, John, Janus, Edward D., Kangaharan, Nadarajah, Keech, Anthony C., Kirke, Andrew B., Kritharides, Leonard, Kyle, Campbell V., Lacaze, Paul, Lambert, Kirsten, Li, Stephen C.H., Malan, Wynand, Maticevic, Stjepana, McQuillan, Brendan M., Mirzaee, Sam, Mori, Trevor A., Morton, Allison C., Colquhoun, David M., Moullin, Joanna C., Nestel, Paul J., Nowak, Kristen J., O'Brien, Richard C., Pachter, Nicholas, Page, Michael M., Pedrotti, Annette, Psaltis, Peter J., Radford, Jan, Reid, Nicola J., Robertson, Elizabeth N., Ryan, Jacqueline D.M., Sarkies, Mitchell N., Schultz, Carl J., Scott, Russell S., Semsarian, Christopher, Simons, Leon A., Spinks, Catherine, Tonkin, Andrew M., van Bockxmeer, Frank, Waddell-Smith, Kathryn E., Ward, Natalie C., White, Harvey D., Wilson, Andrew M., Winship, Ingrid, Woodward, Ann Marie, Nicholls, Stephen J.

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Roadmap for focused ion beam technologies von Höflich, Katja, Hobler, Gerhard, Allen, Frances I., Wirtz, Tom, Rius, Gemma, McElwee-White, Lisa, Krasheninnikov, Arkady V., Schmidt, Matthias, Utke, Ivo, Klingner, Nico, Osenberg, Markus, Córdoba, Rosa, Djurabekova, Flyura, Manke, Ingo, Moll, Philip, Manoccio, Mariachiara, De Teresa, José María, Bischoff, Lothar, Michler, Johann, De Castro, Olivier, Delobbe, Anne, Dunne, Peter, Dobrovolskiy, Oleksandr V., Frese, Natalie, Gölzhäuser, Armin, Mazarov, Paul, Koelle, Dieter, Möller, Wolfhard, Pérez-Murano, Francesc, Philipp, Patrick, Vollnhals, Florian, Hlawacek, Gregor

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SDHC phaeochromocytoma and paraganglioma: A UK‐wide case series von Williams, Sophie T., Chatzikyriakou, Prodromos, Carroll, Paul V., McGowan, Barbara M., Velusamy, Anand, White, Gemma, Obholzer, Rupert, Akker, Scott, Tufton, Nicola, Casey, Ruth T., Maher, Eamonn R., Park, Soo‐Mi, Porteous, Mary, Dyer, Rebecca, Tan, Tricia, Wernig, Florian, Brady, Angela F., Kosicka‐Slawinska, Monika, Whitelaw, Benjamin C., Dorkins, Huw, Lalloo, Fiona, Brennan, Paul, Carlow, Joseph, Martin, Richard, Mitchell, Anna L., Harrison, Rachel, Hawkes, Lara, Newell‐Price, John, Kelsall, Alan, Igbokwe, Rebecca, Adlard, Julian, Schirwani, Schaida, Davidson, Rosemarie, Morrison, Patrick J., Chung, Teng‐Teng, Bowles, Christopher, Izatt, Louise

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Worldwide comparison of survival from childhood leukaemia for 1995–2009, by subtype, age, and sex (CONCORD-2): a population-based study of individual data for 89 828 children from... von Bonaventure, Audrey, Dr, Harewood, Rhea, MSc, Stiller, Charles A, MSc, Gatta, Gemma, MD, Clavel, Jacqueline, MD, Stefan, Daniela C, MD, Carreira, Helena, MSc, Spika, Devon, MSc, Marcos-Gragera, Rafael, PhD, Peris-Bonet, Rafael, Prof, Piñeros, Marion, MD, Sant, Milena, MD, Kuehni, Claudia E, MD, Murphy, Michael F G, MSc, Coleman, Michel P, Prof, Allemani, Claudia, PhD

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Tumour detection and outcomes of surveillance screening in SDHB and SDHD pathogenic variant carriers von White, Gemma, Velusamy, Anand, Anandappa, Samantha, Masucci, Michael, Breen, Louise A, Joshi, Mamta, McGowan, Barbara, Hubbard, Johnathan G H, Obholzer, Rupert, Christodoulou, Dimitra, Jacques, Audrey, Touska, Philip, Hassan, Fahim-Ul, Izatt, Louise, Carroll, Paul V

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Survival variations by country and age for lymphoid and myeloid malignancies in Europe 2000–2007: Results of EUROCARE-5 population-based study von De Angelis, Roberta, Minicozzi, Pamela, Sant, Milena, Dal Maso, Luigino, Brewster, David H, Osca-Gelis, Gemma, Visser, Otto, Maynadié, Marc, Marcos-Gragera, Rafael, Troussard, Xavier, Agius, Dominic, Roazzi, Paolo, Meneghini, Elisabetta, Monnereau, Alain

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