Discovery of Clinically Approved Agents That Promote Suppression of Cystic Fibrosis Transmembrane Conductance Regulator Nonsense Mutations von Mutyam, Venkateshwar, Du, Ming, Xue, Xiaojiao, Keeling, Kim M, White, E Lucile, Bostwick, J Robert, Rasmussen, Lynn, Liu, Bo, Mazur, Marina, Hong, Jeong S, Falk Libby, Emily, Liang, Feng, Shang, Haibo, Mense, Martin, Suto, Mark J, Bedwell, David M, Rowe, Steven M

Volltext

Ultrasound tightening of facial and neck skin: A rater-blinded prospective cohort study von Alam, Murad, MD, MSCI, White, Lucile E., MD, Martin, Nicolle, MD, Witherspoon, Joslyn, MD, MPH, Yoo, Simon, MD, West, Dennis P., PhD

Volltext

Discovery of a novel inhibitor of kinesin-like protein KIFC1 von Zhang, Wei, Zhai, Ling, Wang, Yimin, Boohaker, Rebecca J, Lu, Wenyan, Gupta, Vandana V, Padmalayam, Indira, Bostwick, Robert J, White, E Lucile, Ross, Larry J, Maddry, Joseph, Ananthan, Subramaniam, Augelli-Szafran, Corinne E, Suto, Mark J, Xu, Bo, Li, Rongbao, Li, Yonghe

Volltext

Combining Computational Methods for Hit to Lead Optimization in Mycobacterium Tuberculosis Drug Discovery von Ekins, Sean, Freundlich, Joel S., Hobrath, Judith V., Lucile White, E., Reynolds, Robert C.

Volltext

Revisiting the β-Lactams for Tuberculosis Therapy with a Compound-Compound Synthetic Lethality Approach von Xiao, Shiqi, Guo, Haidan, Weiner, Warren S, Maddox, Clinton, Mao, Chunhong, Gunosewoyo, Hendra, Pelly, Shaaretha, White, E Lucile, Rasmussen, Lynn, Schoenen, Frank J, Aubé, Jeffrey, Bishai, William R, Lun, Shichun

Volltext

High-throughput screening for inhibitors of Mycobacterium tuberculosis H37Rv von Ananthan, Subramaniam, Faaleolea, Ellen R, Goldman, Robert C, Hobrath, Judith V, Kwong, Cecil D, Laughon, Barbara E, Maddry, Joseph A, Mehta, Alka, Rasmussen, Lynn, Reynolds, Robert C, Secrist, John A, Shindo, Nice, Showe, Dustin N, Sosa, Melinda I, Suling, William J, White, E. Lucile

Volltext

A High-Throughput Screening Assay for Inhibitors of Bacterial Motility Identifies a Novel Inhibitor of the Na+-Driven Flagellar Motor and Virulence Gene Expression in Vibrio choler... von RASMUSSEN, Lynn, LUCILE WHITE, E, PATHAK, Ashish, AYALA, Julio C, HONGXIA WANG, WU, Jian-He, BENITEZ, Jorge A, SILVA, Anisia J

Volltext

Redoxal, an inhibitor of de novo pyrimidine biosynthesis, augments APOBEC3G antiviral activity against human immunodeficiency virus type 1 von Pery, Erez, Sheehy, Ann, Miranda Nebane, N, Misra, Vikas, Mankowski, Marie K, Rasmussen, Lynn, Lucile White, E, Ptak, Roger G, Gabuzda, Dana

Volltext

Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule The... von Chung, W Joon, Goeckeler-Fried, Jennifer L, Havasi, Viktoria, Chiang, Annette, Rowe, Steven M, Plyler, Zackery E, Hong, Jeong S, Mazur, Marina, Piazza, Gary A, Keeton, Adam B, White, E Lucile, Rasmussen, Lynn, Weissman, Allan M, Denny, R Aldrin, Brodsky, Jeffrey L, Sorscher, Eric J

Volltext

High throughput screening of a library based on kinase inhibitor scaffolds against Mycobacterium tuberculosis H37Rv von Reynolds, Robert C, Ananthan, Subramaniam, Faaleolea, Ellen, Hobrath, Judith V, Kwong, Cecil D, Maddox, Clinton, Rasmussen, Lynn, Sosa, Melinda I, Thammasuvimol, Elizabeth, White, E. Lucile, Zhang, Wei, Secrist, John A

Volltext

Antituberculosis activity of the molecular libraries screening center network library von Maddry, Joseph A, Ananthan, Subramaniam, Goldman, Robert C, Hobrath, Judith V, Kwong, Cecil D, Maddox, Clinton, Rasmussen, Lynn, Reynolds, Robert C, Secrist, John A, Sosa, Melinda I, White, E. Lucile, Zhang, Wei

Volltext

Qualification of the Hemagglutination Inhibition Assay in Support of Pandemic Influenza Vaccine Licensure von Noah, Diana L, Hill, Heather, Hines, David, White, E Lucile, Wolff, Mark C

Volltext

Novel pyridopyrazine and pyrimidothiazine derivatives as FtsZ inhibitors von Mathew, Bini, Srivastava, Shefali, Ross, Larry J., Suling, William J., White, E. Lucile, Woolhiser, Lisa K., Lenaerts, Anne J., Reynolds, Robert C.

Volltext

A cell-based luminescence assay is effective for high-throughput screening of potential influenza antivirals von Noah, James W., Severson, William, Noah, Diana L., Rasmussen, Lynn, White, E. Lucile, Jonsson, Colleen B.

Volltext

Effects of an unusual poison identify a lifespan role for Topoisomerase 2 in Saccharomyces cerevisiae von Tombline, Gregory, Millen, Jonathan I, Polevoda, Bogdan, Rapaport, Matan, Baxter, Bonnie, Van Meter, Michael, Gilbertson, Matthew, Madrey, Joe, Piazza, Gary A, Rasmussen, Lynn, Wennerberg, Krister, White, E Lucile, Nitiss, John L, Goldfarb, David S

Volltext

Lifting the mask: identification of new small molecule inhibitors of uropathogenic Escherichia coli group 2 capsule biogenesis von Goller, Carlos C, Arshad, Mehreen, Noah, James W, Ananthan, Subramaniam, Evans, Carrie W, Nebane, N Miranda, Rasmussen, Lynn, Sosa, Melinda, Tower, Nichole A, White, E Lucile, Neuenswander, Benjamin, Porubsky, Patrick, Maki, Brooks E, Rogers, Steven A, Schoenen, Frank, Seed, Patrick C

Volltext

Health utilities associated with nonmelanoma skin cancer von Alam, Murad, Kim, John Y.S., Swary, Jillian H., White, Lucile E., Ciurea, Ana, Dave, Loma, Brieva, Joaquin, Yoo, Simon

Volltext

Structure of Mycobacterium tuberculosis FtsZ Reveals Unexpected, G Protein-like Conformational Switches von Leung, Adelaine K.W., Lucile White, E., Ross, Larry J., Reynolds, Robert C., DeVito, Joseph A., Borhani, David W.

Volltext

Development and Validation of a High-Throughput Screen for Inhibitors of SARS CoV and Its Application in Screening of a 100,000-Compound Library von Severson, William E., Shindo, Nice, Sosa, Mindy, Fletcher, III, Thomas, White, E. Lucile, Ananthan, Subramaniam, Jonsson, Colleen B.

Volltext

Advancing Biological Understanding and Therapeutics Discovery with Small-Molecule Probes von Schreiber, Stuart L., Kotz, Joanne D., Li, Min, Aubé, Jeffrey, Austin, Christopher P., Reed, John C., Rosen, Hugh, White, E. Lucile, Sklar, Larry A., Lindsley, Craig W., Alexander, Benjamin R., Bittker, Joshua A., Clemons, Paul A., de Souza, Andrea, Foley, Michael A., Palmer, Michelle, Shamji, Alykhan F., Wawer, Mathias J., McManus, Owen, Wu, Meng, Zou, Beiyan, Yu, Haibo, Golden, Jennifer E., Schoenen, Frank J., Simeonov, Anton, Jadhav, Ajit, Jackson, Michael R., Pinkerton, Anthony B., Chung, Thomas D.Y., Griffin, Patrick R., Cravatt, Benjamin F., Hodder, Peter S., Roush, William R., Roberts, Edward, Chung, Dong-Hoon, Jonsson, Colleen B., Noah, James W., Severson, William E., Ananthan, Subramaniam, Edwards, Bruce, Oprea, Tudor I., Conn, P. Jeffrey, Hopkins, Corey R., Wood, Michael R., Stauffer, Shaun R., Emmitte, Kyle A., Brady, Linda S., Driscoll, Jamie, Li, Ingrid Y., Loomis, Carson R., Margolis, Ronald N., Michelotti, Enrique, Perry, Mary E., Pillai, Ajay, Yao, Yong

Volltext