Comprehensive evaluation of canonical versus Dicer-substrate siRNA in vitro and in vivo von Foster, Donald J, Barros, Scott, Duncan, Rick, Shaikh, Sarfraz, Cantley, William, Dell, Amy, Bulgakova, Elena, O'Shea, Jonathan, Taneja, Nate, Kuchimanchi, Satya, Sherrill, Christopher B, Akinc, Akin, Hinkle, Gregory, Seila White, Amy C, Pang, Bo, Charisse, Klaus, Meyers, Rachel, Manoharan, Muthiah, Elbashir, Sayda M

Volltext

First-in-humans trial of an RNA interference therapeutic targeting VEGF and KSP in cancer patients with liver involvement von Tabernero, Josep, Shapiro, Geoffrey I, LoRusso, Patricia M, Cervantes, Andres, Schwartz, Gary K, Weiss, Glen J, Paz-Ares, Luis, Cho, Daniel C, Infante, Jeffrey R, Alsina, Maria, Gounder, Mrinal M, Falzone, Rick, Harrop, Jamie, White, Amy C Seila, Toudjarska, Iva, Bumcrot, David, Meyers, Rachel E, Hinkle, Gregory, Svrzikapa, Nenad, Hutabarat, Renta M, Clausen, Valerie A, Cehelsky, Jeffrey, Nochur, Saraswathy V, Gamba-Vitalo, Christina, Vaishnaw, Akshay K, Sah, Dinah W Y, Gollob, Jared A, Burris, 3rd, Howard A

Volltext

3′-Modification stabilizes mRNA and increases translation in cells von Gampe, Christian, White, Amy C. Seila, Siva, Swetha, Zécri, Frédéric, Diener, John

Volltext