Tryptophan, kynurenine pathway, and diabetic ketoacidosis in type 1 diabetes von Hoffman, William H., Whelan, Stephen A., Lee, Norman

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Programmable gene regulation for metabolic engineering using decoy transcription factor binding sites von Wang, Tiebin, Tague, Nathan, Whelan, Stephen A, Dunlop, Mary J

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Metabolites in a mouse cancer model enhance venous thrombogenicity through the aryl hydrocarbon receptor–tissue factor axis von Belghasem, Mostafa, Roth, Daniel, Richards, Sean, Napolene, Marc Arthur, Walker, Joshua, Yin, Wenqing, Arinze, Nkiruka, Lyle, Chimera, Spencer, Cheryl, Francis, Jean M., Thompson, Cristal, Andry, Christopher, Whelan, Stephen A., Lee, Norman, Ravid, Katya, Chitalia, Vipul C.

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Tryptophan metabolites suppress the Wnt pathway and promote adverse limb events in chronic kidney disease von Arinze, Nkiruka V, Yin, Wenqing, Lotfollahzadeh, Saran, Napoleon, Marc Arthur, Richards, Sean, Walker, Joshua A, Belghasem, Mostafa, Ravid, Jonathan D, Hassan Kamel, Mohamed, Whelan, Stephen A, Lee, Norman, Siracuse, Jeffrey J, Anderson, Stephan, Farber, Alik, Sherr, David, Francis, Jean, Hamburg, Naomi M, Rahimi, Nader, Chitalia, Vipul C

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The metabolite α-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR von Chin, Randall M., Fu, Xudong, Pai, Melody Y., Vergnes, Laurent, Hwang, Heejun, Deng, Gang, Diep, Simon, Lomenick, Brett, Meli, Vijaykumar S., Monsalve, Gabriela C., Hu, Eileen, Whelan, Stephen A., Wang, Jennifer X., Jung, Gwanghyun, Solis, Gregory M., Fazlollahi, Farbod, Kaweeteerawat, Chitrada, Quach, Austin, Nili, Mahta, Krall, Abby S., Godwin, Hilary A., Chang, Helena R., Faull, Kym F., Guo, Feng, Jiang, Meisheng, Trauger, Sunia A., Saghatelian, Alan, Braas, Daniel, Christofk, Heather R., Clarke, Catherine F., Teitell, Michael A., Petrascheck, Michael, Reue, Karen, Jung, Michael E., Frand, Alison R., Huang, Jing

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Epithelial Mesenchymal Transition Induces Aberrant Glycosylation through Hexosamine Biosynthetic Pathway Activation von Lucena, Miguel C., Carvalho-Cruz, Patricia, Donadio, Joana L., Oliveira, Isadora A., de Queiroz, Rafaela M., Marinho-Carvalho, Monica M., Sola-Penna, Mauro, de Paula, Iron F., Gondim, Katia C., McComb, Mark E., Costello, Catherine E., Whelan, Stephen A., Todeschini, Adriane R., Dias, Wagner B.

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Biosynthetic Machinery Involved in Aberrant Glycosylation: Promising Targets for Developing of Drugs Against Cancer von Vasconcelos-Dos-Santos, Andréia, Oliveira, Isadora A, Lucena, Miguel Clodomiro, Mantuano, Natalia Rodrigues, Whelan, Stephen A, Dias, Wagner Barbosa, Todeschini, Adriane Regina

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Assessment of a 60-Biomarker Health Surveillance Panel (HSP) on Whole Blood from Remote Sampling Devices by Targeted LC/MRM-MS and Discovery DIA-MS Analysis von Whelan, Stephen A., Hendricks, Nathan, Dwight, Zachary L., Fu, Qin, Moradian, Annie, Van Eyk, Jennifer E., Mockus, Susan M.

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Indoleamine 2,3-dioxygenase-1, a Novel Therapeutic Target for Post-Vascular Injury Thrombosis in CKD von Walker, Joshua A., Richards, Sean, Whelan, Stephen A., Yoo, Sung Bok, Russell, Teresa L., Arinze, Nkiruka, Lotfollahzadeh, Saran, Napoleon, Marc A., Belghasem, Mostafa, Lee, Norman, Dember, Laura M., Ravid, Katya, Chitalia, Vipul C.

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Regulation of the O-Linked β-N-Acetylglucosamine Transferase by Insulin Signaling von Whelan, Stephen A., Lane, M. Daniel, Hart, Gerald W.

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Overexpression of Catalase Diminishes Oxidative Cysteine Modifications of Cardiac Proteins von Yao, Chunxiang, Behring, Jessica B, Shao, Di, Sverdlov, Aaron L, Whelan, Stephen A, Elezaby, Aly, Yin, Xiaoyan, Siwik, Deborah A, Seta, Francesca, Costello, Catherine E, Cohen, Richard A, Matsui, Reiko, Colucci, Wilson S, McComb, Mark E, Bachschmid, Markus M

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Comparative Proteomics Reveals Dysregulated Mitochondrial O‑GlcNAcylation in Diabetic Hearts von Ma, Junfeng, Banerjee, Partha, Whelan, Stephen A, Liu, Ting, Wei, An-Chi, Ramirez-Correa, Genaro, McComb, Mark E, Costello, Catherine E, O’Rourke, Brian, Murphy, Anne, Hart, Gerald W

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Temporal and tissue-specific activation of aryl hydrocarbon receptor in discrete mouse models of kidney disease von Walker, Joshua A., Richards, Sean, Belghasem, Mostafa E., Arinze, Nkiruka, Yoo, Sung Bok, Tashjian, Joseph Y., Whelan, Stephen A., Lee, Norman, Kolachalama, Vijaya B., Francis, Jean, Ravid, Katya, Sherr, David, Chitalia, Vipul C.

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Implications for an Imidazole-2-yl Carbene Intermediate in the Rhodanase-Catalyzed C–S Bond Formation Reaction of Anaerobic Ergothioneine Biosynthesis von Cheng, Ronghai, Lai, Rui, Peng, Chao, Lopez, Juan, Li, Zhihong, Naowarojna, Nathchar, Li, Kelin, Wong, Christina, Lee, Norman, Whelan, Stephen A, Qiao, Lu, Grinstaff, Mark W, Wang, Jiangyun, Cui, Qiang, Liu, Pinghua

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Tryptophan Metabolites Target Transmembrane and Immunoglobulin Domain-Containing 1 Signaling to Augment Renal Tubular Injury von Belghasem, Mostafa, Yin, Wenqing, Lotfollahzadeh, Saran, Yang, Xiaosheng, Meyer, Rosana D., Napoleon, Marc A., Sellinger, Isaac E., Vazirani, Aniket, Metrikova, Elena, Jose, Asha, Zhebrun, Anna, Whelan, Stephen A., Lee, Norman, Rahimi, Nader, Chitalia, Vipul C.

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Regulation of Insulin Receptor Substrate 1 (IRS-1)/AKT Kinase-mediated Insulin Signaling by O-Linked β-N-Acetylglucosamine in 3T3-L1 Adipocytes von Whelan, Stephen A., Dias, Wagner B., Thiruneelakantapillai, Lakshmanan, Lane, M. Daniel, Hart, Gerald W.

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Single-Step Replacement of an Unreactive C–H Bond by a C–S Bond Using Polysulfide as the Direct Sulfur Source in the Anaerobic Ergothioneine Biosynthesis von Cheng, Ronghai, Wu, Lian, Lai, Rui, Peng, Chao, Naowarojna, Nathchar, Hu, Weiyao, Li, Xinhao, Whelan, Stephen A, Lee, Norman, Lopez, Juan, Zhao, Changming, Yong, Youhua, Xue, Jiahui, Jiang, Xuefeng, Grinstaff, Mark W, Deng, Zixin, Chen, Jiesheng, Cui, Qiang, Zhou, Jiahai, Liu, Pinghua

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Multi-omics after O-GlcNAc alteration identified cellular processes promoting aneuploidy after loss of O-GlcNAc transferase von Boyd, Samuel S., Robarts, Dakota R., Nguyen, Khue, Villar, Maite, Alghusen, Ibtihal M., Kotulkar, Manasi, Denson, Aspin, Fedosyuk, Halyna, Whelan, Stephen A., Lee, Norman C.Y., Hanover, John, Dias, Wagner B., Tan, Ee Phie, McGreal, Steven R., Artigues, Antonio, Swerdlow, Russell H., Thompson, Jeffrey A., Apte, Udayan, Slawson, Chad

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Characterization of the Human NEK7 Interactome Suggests Catalytic and Regulatory Properties Distinct from Those of NEK6 von de Souza, Edmarcia Elisa, Meirelles, Gabriela Vaz, Godoy, Bárbara Biatriz, Perez, Arina Marina, Smetana, Juliana Helena Costa, Doxsey, Stephen J, McComb, Mark E, Costello, Catherine E, Whelan, Stephen A, Kobarg, Jörg

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Judy Yates von Whelan, Stephen

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