Contrasting effects of sleep fragmentation and angiotensin-II treatment upon pro-inflammatory responses of mice von Ensminger, David C., Wheeler, Nicholas D., Al Makki, Reem, Eads, Kristen N., Ashley, Noah T.

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Alpha- and beta- adrenergic receptors regulate inflammatory responses to acute and chronic sleep fragmentation in mice von Wheeler, Nicholas D., Ensminger, David C., Rowe, Megan M., Wriedt, Zachary S., Ashley, Noah T.

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Mapping the proteo-genomic convergence of human diseases von Pietzner, Maik, Wheeler, Eleanor, Carrasco-Zanini, Julia, Cortes, Adrian, Koprulu, Mine, Woerheide, Maria A., Oerton, Erin, Cook, James, Stewart, Isobel D., Kerrison, Nicola D., Luan, Jian'an, Raffler, Johannes, Arnold, Matthias, Arlt, Wiebke, O'Rahilly, Stephen, Kastenmueller, Gabi, Gamazon, Eric R., Hingorani, Aroon D., Scott, Robert A., Wareham, Nicholas J., Langenberg, Claudia

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Synergistic insights into human health from aptamer- and antibody-based proteomic profiling von Pietzner, Maik, Wheeler, Eleanor, Carrasco-Zanini, Julia, Kerrison, Nicola D., Oerton, Erin, Koprulu, Mine, Luan, Jian’an, Hingorani, Aroon D., Williams, Steve A., Wareham, Nicholas J., Langenberg, Claudia

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Genetic architecture of host proteins involved in SARS-CoV-2 infection von Pietzner, Maik, Wheeler, Eleanor, Carrasco-Zanini, Julia, Raffler, Johannes, Kerrison, Nicola D., Oerton, Erin, Auyeung, Victoria P. W., Luan, Jian’an, Finan, Chris, Casas, Juan P., Ostroff, Rachel, Williams, Steve A., Kastenmüller, Gabi, Ralser, Markus, Gamazon, Eric R., Wareham, Nicholas J., Hingorani, Aroon D., Langenberg, Claudia

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Low-Loss, Extreme Subdiffraction Photon Confinement via Silicon Carbide Localized Surface Phonon Polariton Resonators von Caldwell, Joshua D, Glembocki, Orest J, Francescato, Yan, Sharac, Nicholas, Giannini, Vincenzo, Bezares, Francisco J, Long, James P, Owrutsky, Jeffrey C, Vurgaftman, Igor, Tischler, Joseph G, Wheeler, Virginia D, Bassim, Nabil D, Shirey, Loretta M, Kasica, Richard, Maier, Stefan A

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TAL effector driven induction of a SWEET gene confers susceptibility to bacterial blight of cotton von Cox, Kevin L., Meng, Fanhong, Wilkins, Katherine E., Li, Fangjun, Wang, Ping, Booher, Nicholas J., Carpenter, Sara C. D., Chen, Li-Qing, Zheng, Hui, Gao, Xiquan, Zheng, Yi, Fei, Zhangjun, Yu, John Z., Isakeit, Thomas, Wheeler, Terry, Frommer, Wolf B., He, Ping, Bogdanove, Adam J., Shan, Libo

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A cross-platform approach identifies genetic regulators of human metabolism and health von Lotta, Luca A., Pietzner, Maik, Stewart, Isobel D., Wittemans, Laura B. L., Li, Chen, Bonelli, Roberto, Raffler, Johannes, Biggs, Emma K., Oliver-Williams, Clare, Auyeung, Victoria P. W., Luan, Jian’an, Wheeler, Eleanor, Paige, Ellie, Surendran, Praveen, Michelotti, Gregory A., Scott, Robert A., Burgess, Stephen, Zuber, Verena, Sanderson, Eleanor, Koulman, Albert, Imamura, Fumiaki, Forouhi, Nita G., Khaw, Kay-Tee, Griffin, Julian L., Wood, Angela M., Kastenmüller, Gabi, Danesh, John, Butterworth, Adam S., Gribble, Fiona M., Reimann, Frank, Bahlo, Melanie, Fauman, Eric, Wareham, Nicholas J., Langenberg, Claudia

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ELF5 is a potential respiratory epithelial cell-specific risk gene for severe COVID-19 von Pietzner, Maik, Chua, Robert Lorenz, Wheeler, Eleanor, Jechow, Katharina, Willett, Julian D. S., Radbruch, Helena, Trump, Saskia, Heidecker, Bettina, Zeberg, Hugo, Heppner, Frank L., Eils, Roland, Mall, Marcus A., Richards, J. Brent, Sander, Leif-Erik, Lehmann, Irina, Lukassen, Sören, Wareham, Nicholas J., Conrad, Christian, Langenberg, Claudia

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Cross-species identification of genomic drivers of squamous cell carcinoma development across preneoplastic intermediates von Chitsazzadeh, Vida, Coarfa, Cristian, Drummond, Jennifer A., Nguyen, Tri, Joseph, Aaron, Chilukuri, Suneel, Charpiot, Elizabeth, Adelmann, Charles H., Ching, Grace, Nguyen, Tran N., Nicholas, Courtney, Thomas, Valencia D., Migden, Michael, MacFarlane, Deborah, Thompson, Erika, Shen, Jianjun, Takata, Yoko, McNiece, Kayla, Polansky, Maxim A., Abbas, Hussein A., Rajapakshe, Kimal, Gower, Adam, Spira, Avrum, Covington, Kyle R., Xiao, Weimin, Gunaratne, Preethi, Pickering, Curtis, Frederick, Mitchell, Myers, Jeffrey N., Shen, Li, Yao, Hui, Su, Xiaoping, Rapini, Ronald P., Wheeler, David A., Hawk, Ernest T., Flores, Elsa R., Tsai, Kenneth Y.

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Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes von Dentro, Stefan C., Leshchiner, Ignaty, Haase, Kerstin, Wintersinger, Jeff, Deshwar, Amit G., Yu, Kaixian, Rubanova, Yulia, Macintyre, Geoff, Demeulemeester, Jonas, Vázquez-García, Ignacio, Kleinheinz, Kortine, Livitz, Dimitri G., Malikic, Salem, Donmez, Nilgun, Sengupta, Subhajit, Anur, Pavana, Jolly, Clemency, Rosebrock, Daniel, Schumacher, Steven E., Fittall, Matthew, Drews, Ruben M., Yao, Xiaotong, Lee, Juhee, Schlesner, Matthias, Zhu, Hongtu, Adams, David J., McGranahan, Nicholas, Swanton, Charles, Getz, Gad, Boutros, Paul C., Imielinski, Marcin, Beroukhim, Rameen, Sahinalp, S. Cenk, Ji, Yuan, Peifer, Martin, Martincorena, Inigo, Markowetz, Florian, Mustonen, Ville, Yuan, Ke, Gerstung, Moritz, Spellman, Paul T., Wang, Wenyi, Wedge, David C., Dentro, Stefan C., Leshchiner, Ignaty, Gerstung, Moritz, Jolly, Clemency, Haase, Kerstin, Tarabichi, Maxime, Wintersinger, Jeff, Deshwar, Amit G., Yu, Kaixian, Rubanova, Yulia, Macintyre, Geoff, Demeulemeester, Jonas, Anur, Pavana, Beroukhim, Rameen, Boutros, Paul C., Bowtell, David D., Cao, Shaolong, Cmero, Marek, Cun, Yupeng, Dawson, Kevin J., Donmez, Nilgun, Drews, Ruben M., Eils, Roland, Fan, Yu, Fittall, Matthew, Getz, Gad, Ha, Gavin, Imielinski, Marcin, Ji, Yuan, Kleinheinz, Kortine, Lee, Juhee, Lee-Six, Henry, Livitz, Dimitri G., Malikic, Salem, Markowetz, Florian, Martincorena, Inigo, Mustonen, Ville, Oesper, Layla, Peifer, Martin, Peto, Myron, Raphael, Benjamin J., Rosebrock, Daniel, Salcedo, Adriana, Schumacher, Steven E., Sengupta, Subhajit, Shi, Ruian, Spiro, Oliver, Vázquez-García, Ignacio, Vembu, Shankar, Wheeler, David A., Yao, Xiaotong, Yuan, Ke, Wang, Wenyi, Morris, Quaid D., Spellman, Paul T., Wedge, David C., Van Loo, Peter

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All-Inorganic Germanium Nanocrystal Films by Cationic Ligand Exchange von Wheeler, Lance M, Nichols, Asa W, Chernomordik, Boris D, Anderson, Nicholas C, Beard, Matthew C, Neale, Nathan R

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Genetically Predicted Glucose-Dependent Insulinotropic Polypeptide (GIP) Levels and Cardiovascular Disease Risk Are Driven by Distinct Causal Variants in the GIPR Region von Bowker, Nicholas, Hansford, Robert, Burgess, Stephen, Foley, Christopher N., Auyeung, Victoria P. W., Erzurumluoglu, A. Mesut, Stewart, Isobel D., Wheeler, Eleanor, Pietzner, Maik, Gribble, Fiona, Reimann, Frank, Bhatnagar, Pallav, Coghlan, Matthew P., Wareham, Nicholas J., Langenberg, Claudia

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Efficacy of three neuroprotective drugs in secondary progressive multiple sclerosis (MS-SMART): a phase 2b, multiarm, double-blind, randomised placebo-controlled trial von Chataway, Jeremy, De Angelis, Floriana, Connick, Peter, Parker, Richard A, Plantone, Domenico, Doshi, Anisha, John, Nevin, Stutters, Jonathan, MacManus, David, Prados Carrasco, Ferran, Barkhof, Frederik, Ourselin, Sebastien, Braisher, Marie, Ross, Moira, Cranswick, Gina, Pavitt, Sue H, Giovannoni, Gavin, Gandini Wheeler-Kingshott, Claudia Angela, Hawkins, Clive, Sharrack, Basil, Bastow, Roger, Weir, Christopher J, Stallard, Nigel, Chandran, Siddharthan, Chataway, Jeremy, Gandini Wheeler-Kingshott, Claudia A.M., De Angelis, Floriana, Plantone, Domenico, Doshi, Anisha, John, Nevin, Williams, Thomas, Braisher, Marie, Beyene, Tiggy, Bassan, Vanessa, Zapata, Alvin, Chandran, Siddharthan, Connick, Peter, Lyle, Dawn, Cameron, James, Mollison, Daisy, Colville, Shuna, Dhillon, Baljean, Weir, Christopher J., Parker, Richard A., Ross, Moira, Cranswick, Gina, Giovannoni, Gavin, Gnanapavan, Sharmilee, Nicholas, Richard, Rashid, Waqar, Aram, Julia, Ford, Helen, Overell, James, Young, Carolyn, Arndt, Heinke, Duddy, Martin, Guadagno, Joe, Evangelou, Nikolaos, Craner, Matthew, Palace, Jacqueline, Hobart, Jeremy, Sharrack, Basil, Paling, David, Hawkins, Clive, Kalra, Seema, McLean, Brendan, Stallard, Nigel, Bastow, Roger

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Development and validation of a metabolite score for red meat intake: an observational cohort study and randomized controlled dietary intervention von Li, Chunxiao, Imamura, Fumiaki, Wedekind, Roland, Stewart, Isobel D, Pietzner, Maik, Wheeler, Eleanor, Forouhi, Nita G, Langenberg, Claudia, Scalbert, Augustin, Wareham, Nicholas J

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Identification of Rare Loss-of-Function Genetic Variation Regulating Body Fat Distribution von Koprulu, Mine, Zhao, Yajie, Wheeler, Eleanor, Dong, Liang, Rocha, Nuno, Li, Chen, Griffin, John D, Patel, Satish, Van de Streek, Marcel, Glastonbury, Craig A, Stewart, Isobel D, Day, Felix R, Luan, Jian'an, Bowker, Nicholas, Wittemans, Laura B L, Kerrison, Nicola D, Cai, Lina, Lucarelli, Debora M E, Barroso, Inês, McCarthy, Mark I, Scott, Robert A, Saudek, Vladimir, Small, Kerrin S, Wareham, Nicholas J, Semple, Robert K, Perry, John R B, O'Rahilly, Stephen, Lotta, Luca A, Langenberg, Claudia, Savage, David B

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Extracellular matrix modulates T cell clearance of malignant cells in vitro von Robertson, Claire, Sebastian, Aimy, Hinckley, Aubree, Rios-Arce, Naiomy D., Hynes, William F., Edwards, Skye A., He, Wei, Hum, Nicholas R., Wheeler, Elizabeth K., Loots, Gabriela G., Coleman, Matthew A., Moya, Monica L.

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Induced Pluripotent Stem Cells from Patients with Huntington's Disease Show CAG-Repeat-Expansion-Associated Phenotypes von Mattis, Virginia B, Svendsen, Soshana P, Ebert, Allison, Svendsen, Clive N, King, Alvin R, Casale, Malcolm, Winokur, Sara T, Batugedara, Gayani, Vawter, Marquis, Donovan, Peter J, Lock, Leslie F, Thompson, Leslie M, Zhu, Yu, Fossale, Elisa, Singh Atwal, Ranjit, Gillis, Tammy, Mysore, Jayalakshmi, Li, Jian-hong, Seong, IhnSik, Shen, Yiping, Chen, Xiaoli, Wheeler, Vanessa C, MacDonald, Marcy E, Gusella, James F, Akimov, Sergey, Arbez, Nicolas, Juopperi, Tarja, Ratovitski, Tamara, Chiang, Jason H, Kim, Woon Roung, Chighladze, Eka, Watkin, Erin, Zhong, Chun, Makri, Georgia, Cole, Robert N, Margolis, Russell L, Song, Hongjun, Ming, Guoli, Ross, Christopher A, Kaye, Julia A, Daub, Aaron, Sharma, Punita, Mason, Amanda R, Finkbeiner, Steven, Yu, Junying, Thomson, James A, Rushton, David, Brazier, Stephen P, Battersby, Alysia A, Redfern, Amanda, Tseng, Hsui-Er, Harrison, Alexander W, Kemp, Paul J, Allen, Nicholas D, Onorati, Marco, Castiglioni, Valentina, Cattaneo, Elena, Arjomand, Jamshid

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Exome sequencing of individuals with Huntington’s disease implicates FAN1 nuclease activity in slowing CAG expansion and disease onset von McAllister, Branduff, Donaldson, Jasmine, Binda, Caroline S., Powell, Sophie, Chughtai, Uroosa, Edwards, Gareth, Stone, Joseph, Lobanov, Sergey, Elliston, Linda, Schuhmacher, Laura-Nadine, Rees, Elliott, Menzies, Georgina, Ciosi, Marc, Maxwell, Alastair, Chao, Michael J., Hong, Eun Pyo, Lucente, Diane, Wheeler, Vanessa, Lee, Jong-Min, MacDonald, Marcy E., Long, Jeffrey D., Aylward, Elizabeth H., Landwehrmeyer, G. Bernhard, Rosser, Anne E., Paulsen, Jane S., Williams, Nigel M., Gusella, James F., Monckton, Darren G., Allen, Nicholas D., Holmans, Peter, Jones, Lesley, Massey, Thomas H.

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IL-17A Increases Doxorubicin Efficacy in Triple Negative Breast Cancer von Hum, Nicholas R., Sebastian, Aimy, Martin, Kelly A., Rios-Arce, Naiomy D., Gilmore, Sean F., Gravano, David M., Wheeler, Elizabeth K., Coleman, Matthew A., Loots, Gabriela G.

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