Mapping the proteo-genomic convergence of human diseases von Pietzner, Maik, Wheeler, Eleanor, Carrasco-Zanini, Julia, Cortes, Adrian, Koprulu, Mine, Woerheide, Maria A., Oerton, Erin, Cook, James, Stewart, Isobel D., Kerrison, Nicola D., Luan, Jian'an, Raffler, Johannes, Arnold, Matthias, Arlt, Wiebke, O'Rahilly, Stephen, Kastenmueller, Gabi, Gamazon, Eric R., Hingorani, Aroon D., Scott, Robert A., Wareham, Nicholas J., Langenberg, Claudia

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Synergistic insights into human health from aptamer- and antibody-based proteomic profiling von Pietzner, Maik, Wheeler, Eleanor, Carrasco-Zanini, Julia, Kerrison, Nicola D., Oerton, Erin, Koprulu, Mine, Luan, Jian’an, Hingorani, Aroon D., Williams, Steve A., Wareham, Nicholas J., Langenberg, Claudia

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Human Gain-of-Function MC4R Variants Show Signaling Bias and Protect against Obesity von Lotta, Luca A., Mokrosiński, Jacek, Mendes de Oliveira, Edson, Li, Chen, Sharp, Stephen J., Luan, Jian’an, Brouwers, Bas, Ayinampudi, Vikram, Bowker, Nicholas, Kerrison, Nicola, Kaimakis, Vasileios, Hoult, Diana, Stewart, Isobel D., Wheeler, Eleanor, Day, Felix R., Perry, John R.B., Langenberg, Claudia, Wareham, Nicholas J., Farooqi, I. Sadaf

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Genetic architecture of host proteins involved in SARS-CoV-2 infection von Pietzner, Maik, Wheeler, Eleanor, Carrasco-Zanini, Julia, Raffler, Johannes, Kerrison, Nicola D., Oerton, Erin, Auyeung, Victoria P. W., Luan, Jian’an, Finan, Chris, Casas, Juan P., Ostroff, Rachel, Williams, Steve A., Kastenmüller, Gabi, Ralser, Markus, Gamazon, Eric R., Wareham, Nicholas J., Hingorani, Aroon D., Langenberg, Claudia

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Genetic architecture of human thinness compared to severe obesity von Riveros-McKay, Fernando, Mistry, Vanisha, Bounds, Rebecca, Hendricks, Audrey, Keogh, Julia M, Thomas, Hannah, Henning, Elana, Corbin, Laura J, O'Rahilly, Stephen, Zeggini, Eleftheria, Wheeler, Eleanor, Barroso, Inês, Farooqi, I Sadaf

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Causal associations between cardiorespiratory fitness and type 2 diabetes von Cai, Lina, Gonzales, Tomas, Wheeler, Eleanor, Kerrison, Nicola D., Day, Felix R., Langenberg, Claudia, Perry, John R. B., Brage, Soren, Wareham, Nicholas J.

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Mapping the serum proteome to neurological diseases using whole genome sequencing von Png, Grace, Barysenka, Andrei, Repetto, Linda, Navarro, Pau, Shen, Xia, Pietzner, Maik, Wheeler, Eleanor, Wareham, Nicholas J., Langenberg, Claudia, Tsafantakis, Emmanouil, Karaleftheri, Maria, Dedoussis, George, Mälarstig, Anders, Wilson, James F., Gilly, Arthur, Zeggini, Eleftheria

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Mendelian Randomization Analysis of Hemoglobin A1c as a Risk Factor for Coronary Artery Disease von Leong, Aaron, Chen, Ji, Wheeler, Eleanor, Hivert, Marie-France, Liu, Ching-Ti, Merino, Jordi, Dupuis, Josée, Tai, E Shyong, Rotter, Jerome I., Florez, Jose C., Barroso, Inês, Meigs, James B.

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Hypomorphism in human NSMCE2 linked to primordial dwarfism and insulin resistance von Payne, Felicity, Colnaghi, Rita, Rocha, Nuno, Seth, Asha, Harris, Julie, Carpenter, Gillian, Bottomley, William E, Wheeler, Eleanor, Wong, Stephen, Saudek, Vladimir, Savage, David, O'Rahilly, Stephen, Carel, Jean-Claude, Barroso, Inês, O'Driscoll, Mark, Semple, Robert

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Meta-analysis investigating the role of interleukin-6 mediated inflammation in type 2 diabetes von Bowker, Nicholas, Shah, Rupal L., Sharp, Stephen J., Luan, Jian'an, Stewart, Isobel D., Wheeler, Eleanor, Ferreira, Manuel A.R., Baras, Aris, Wareham, Nicholas J., Langenberg, Claudia, Lotta, Luca A.

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GIGYF1 loss of function is associated with clonal mosaicism and adverse metabolic health von Zhao, Yajie, Stankovic, Stasa, Koprulu, Mine, Wheeler, Eleanor, Day, Felix R., Lango Allen, Hana, Kerrison, Nicola D., Pietzner, Maik, Loh, Po-Ru, Wareham, Nicholas J., Langenberg, Claudia, Ong, Ken K., Perry, John R. B.

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ELF5 is a potential respiratory epithelial cell-specific risk gene for severe COVID-19 von Pietzner, Maik, Chua, Robert Lorenz, Wheeler, Eleanor, Jechow, Katharina, Willett, Julian D. S., Radbruch, Helena, Trump, Saskia, Heidecker, Bettina, Zeberg, Hugo, Heppner, Frank L., Eils, Roland, Mall, Marcus A., Richards, J. Brent, Sander, Leif-Erik, Lehmann, Irina, Lukassen, Sören, Wareham, Nicholas J., Conrad, Christian, Langenberg, Claudia

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Genetic determinants of complement activation in the general population von Noce, Damia, Foco, Luisa, Orth-Höller, Dorothea, König, Eva, Barbieri, Giulia, Pietzner, Maik, Ghasemi-Semeskandeh, Dariush, Coassin, Stefan, Fuchsberger, Christian, Gögele, Martin, Del Greco M., Fabiola, De Grandi, Alessandro, Summerer, Monika, Wheeler, Eleanor, Langenberg, Claudia, Lass-Flörl, Cornelia, Pramstaller, Peter Paul, Kronenberg, Florian, Würzner, Reinhard, Pattaro, Cristian

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The influence of rare variants in circulating metabolic biomarkers von Riveros-Mckay, Fernando, Oliver-Williams, Clare, Karthikeyan, Savita, Walter, Klaudia, Kundu, Kousik, Ouwehand, Willem H., Roberts, David, Di Angelantonio, Emanuele, Soranzo, Nicole, Danesh, John, Wheeler, Eleanor, Zeggini, Eleftheria, Butterworth, Adam S., Barroso, Ines

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Genetics of HbA1c: a case study in clinical translation von Leong, Aaron, Wheeler, Eleanor

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Author Correction: Genetic architecture of host proteins involved in SARS-CoV-2 infection von Pietzner, Maik, Wheeler, Eleanor, Carrasco-Zanini, Julia, Raffler, Johannes, Kerrison, Nicola D., Oerton, Erin, Auyeung, Victoria P. W., Luan, Jian’an, Finan, Chris, Casas, Juan P., Ostroff, Rachel, Williams, Steve A., Kastenmüller, Gabi, Ralser, Markus, Gamazon, Eric R., Wareham, Nicholas J., Hingorani, Aroon D., Langenberg, Claudia

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Key Concepts in Genetic Epidemiology von Panoutsopoulou, Kalliope, Wheeler, Eleanor

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PO83 INCLUSION BY DESIGN: RECOMMENDATIONS FOR BUILDING EQUITY IN CLINICALTRIALS THROUGH THE LENS OF METASTATIC BREAST CANCER von Wilcox, Helena, Wheeler, Eleanor, Wait, Suzanne

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Detailed Investigation of the Role of Common and Low-Frequency WFS1 Variants in Type 2 Diabetes Risk von FAWCETT, Katherine A, WHEELER, Eleanor, GLASER, Benjamin, FRANKS, Paul W, MCCARTHY, Mark I, WAREHAM, Nicholas J, SANDHU, Manjinder S, BARROSO, Inês, MORRIS, Andrew P, RICKETTS, Sally L, HALLMANS, Göran, ROLANDSSON, Olov, DALY, Allan, WASSON, Jon, PERMUTT, Alan, HATTERSLEY, Andrew T

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Evaluating the Role of LPIN1 Variation in Insulin Resistance, Body Weight, and Human Lipodystrophy in U.K. Populations von FAWCETT, Katherine A, GRIMSEY, Neil, O'RAHILLY, Stephen, WAREHAM, Nicholas J, BARROSO, Inês, LOOS, Ruth J. F, WHEELER, Eleanor, DALY, Allan, SOOS, Maria, SEMPLE, Robert, SYDDALL, Holly, COOPER, Cyrus, SINIOSSOGLOU, Symeon

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