Synthesis and reactions of 2,3-dihydro-oxazolo[2,3-a]isoindol-5(9bH)-ones von WHARTON, C. J, WRIGGLESWORTH, R

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Inhibitors of pyrimidine biosynthesis. Part 2. The synthesis of amidine phosphonates as potential inhibitors of carbamoyl phosphate synthase von Wharton, Clifford J., Wrigglesworth, Roger

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Protonation equilibria of cardiotonic polyaza heterocycles von BARRACLOUGH, P, FIRMIN, D, RAMACHANDRAN IYER, KING, W. R, LINDON, J. C, NOBBS, M. S, SMITH, S, WHARTON, C. J, WILLIAMS, J. M

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Inhibitors of pyrimidine biosynthesis. Part 1. Synthesis of potential transition-state analogues of aspartate transcarbamylase von Goodson, John J., Wharton, Clifford J., Wrigglesworth, Roger

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The synthesis of peptide β-lactams as potential protease inhibitors von WHARTON, C. J, WRIGGLESWORTH, R, ROWE, M

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Additions and corrections von Leet, John E., Feyer, Alan J., Minard, Robert D., Shamma, Maurice, Shoppee, Charles W., Wharton, Clifford J., Wrigglesworth, Roger

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Synthesis and Inhibitory Activity on Platelet Aggregation of 13′-Aza and Other ω-Chain Modified BW245C Analogues von Barraclough, Paur, Brockwell, Michael, Caldwell, A. Gordon, Demaine, Derek A., Harris, C. John, King, W. Richard, Stepney, Ray J., Wharton, Clifford J., Whittle, Brendan J. R.

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Novel molecular subgroups for clinical classification and outcome prediction in childhood medulloblastoma: a cohort study von Schwalbe, Edward C, PhD, Lindsey, Janet C, PhD, Nakjang, Sirintra, PhD, Crosier, Stephen, PhD, Smith, Amanda J, MSc, Hicks, Debbie, PhD, Rafiee, Gholamreza, PhD, Hill, Rebecca M, PhD, Iliasova, Alice, MSc, Stone, Thomas, MRes, Pizer, Barry, Prof, Michalski, Antony, PhD, Joshi, Abhijit, MBBS, Wharton, Stephen B, Prof, Jacques, Thomas S, PhD, Bailey, Simon, Prof, Williamson, Daniel, PhD, Clifford, Steven C, Prof

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Combined MYC and P53 Defects Emerge at Medulloblastoma Relapse and Define Rapidly Progressive, Therapeutically Targetable Disease von Hill, Rebecca M., Kuijper, Sanne, Lindsey, Janet C., Petrie, Kevin, Schwalbe, Ed C., Barker, Karen, Boult, Jessica K.R., Williamson, Daniel, Ahmad, Zai, Hallsworth, Albert, Ryan, Sarra L., Poon, Evon, Robinson, Simon P., Ruddle, Ruth, Raynaud, Florence I., Howell, Louise, Kwok, Colin, Joshi, Abhijit, Nicholson, Sarah Leigh, Crosier, Stephen, Ellison, David W., Wharton, Stephen B., Robson, Keith, Michalski, Antony, Hargrave, Darren, Jacques, Thomas S., Pizer, Barry, Bailey, Simon, Swartling, Fredrik J., Weiss, William A., Chesler, Louis, Clifford, Steven C.

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The molecular landscape and associated clinical experience in infant medulloblastoma: prognostic significance of second‐generation subtypes von Hicks, D., Rafiee, G., Schwalbe, E. C., Howell, C. I., Lindsey, J. C., Hill, R. M., Smith, A. J., Adidharma, P., Steel, C., Richardson, S., Pease, L., Danilenko, M., Crosier, S., Joshi, A., Wharton, S. B., Jacques, T. S., Pizer, B., Michalski, A., Williamson, D., Bailey, S., Clifford, S. C.

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Abstract LB-201: MYC and TP53 defects interact at medulloblastoma relapse to define rapidly progressive disease and can be targeted therapeutically von Hill, Rebecca M., Kuijper, Sanne, Lindsey, Janet, Schwalbe, Ed C., Barker, Karen, Boult, Jessica, Williamson, Daniel, Ahmad, Zai, Hallsworth, Albert, Ryan, Sarra, Poon, Evon, Robinson, Simon, Ruddle, Ruth, Raynaud, Florence, Howell, Louise, Kwok, Colin, Joshi, Abhijit, Nicholson, Sarah, Crosier, Stephen, Wharton, Stephen, Jacques, Tom, Robson, Keith, Michalski, Antony, Hargrave, Darren, Pizer, Barry, Bailey, Simon, Swartling, Fredrik J., Petrie, Kevin, Weiss, William A., Chesler, Louis, Clifford, Steve

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MYC and TP53 defects interact at medulloblastoma relapse to define rapidly progressive disease and can be targeted therapeutically von Hill, Rebecca M., Kuijper, Sanne, Lindsey, Janet, Schwalbe, Ed C., Barker, Karen, Boult, Jessica, Williamson, Daniel, Ahmad, Zai, Hallsworth, Albert, Ryan, Sarra, Poon, Evon, Robinson, Simon, Ruddle, Ruth, Raynaud, Florence, Howell, Louise, Kwok, Colin, Joshi, Abhijit, Nicholson, Sarah, Crosier, Stephen, Wharton, Stephen, Jacques, Tom, Robson, Keith, Michalski, Antony, Hargrave, Darren, Pizer, Barry, Bailey, Simon, Swartling, Fredrik J., Petrie, Kevin, Weiss, William A., Chesler, Louis, Clifford, Steve

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EPIDEMIOLOGY von Khatua, S., Brown, R., Pearlman, M., Vats, T., Satge, D., Stiller, C., Rutkowski, S., von Bueren, A. O., Lacour, B., Sommelet, D., Nishi, M., Massimino, M., Garre, M.-L., Moreno, F., Hasle, H., Jakab, Z., Greenberg, M., von der Weid, N., Kuehni, C., Zurriaga, O., Vicente, M.-L., Peris-Bonet, R., Benesch, M., Vekemans, M., Sullivan, S., Rickert, C., Fisher, P. G., Von Behren, J., Nelson, D. O., Reynolds, P., Fukuoka, K., Yanagisawa, T., Suzuki, T., Koga, T., Wakiya, K., Adachi, J.-i., Mishima, K., Fujimaki, T., Matsutani, M., Nishikawa, R., Gidding, C., Schieving, J., Wesseling, P., Ligtenberg, M., Hoogerbrugge, N., Jongmans, M., Crosier, S., Nicholson, S. L., Robson, K., Jacques, T., Wharton, S., Bown, N., Michalski, A., Pizer, B., Clifford, S., Sanden, E., Visse, E., Siesjo, P., Darabi, A., Nousome, D., Lupo, P. J., Scheurer, M. E., Nulman, I., Barrera, M., Maxwell, C., Koren, G., Gorelyshev, S., Matuev, K., Lubnin, A., Laskov, M., Lemeneva, N., Mazerkina, N., Khuhlaeva, E., Muller, K., Bruns, F., Pietsch, T., Kortmann, R.-D., Krishnatry, R., Shirsat, N., Kunder, R., Epari, S., Gupta, T., Kurkure, P., Vora, T., Arora, B., Moiyadi, A., Jalali, R., Swieszkowska, E., Dembowska-Baginska, B., Drogosiewicz, M., Filipek, I., Perek-Polnik, M., Grajkowska, W., Perek, D., Johnston, D., Cyr, J., Strother, D., Lafay-Cousin, L., Fryer, C., Scheinemann, K.

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Emergence and maintenance of actionable genetic drivers at medulloblastoma relapse von Richardson, S, Hill, RM, Kui, C, Lindsey, JC, Grabovksa, Y, Keeling, C, Pease, L, Bashton, M, Crosier, S, Vinci, M, André, N, Figarella-Branger, D, Hansford, JR, Lastowska, M, Zakrzewski, K, Jorgensen, M, Pickles, JC, Taylor, MD, Pfister, SM, Wharton, SB, Pizer, B, Michalski, A, Joshi, A, Jacques, TS, Hicks, D, Schwalbe, EC, Williamson, D, Ramaswamy, V, Bailey, S, Clifford, SC

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Advanced molecular pathology for rare tumours: A national feasibility study and model for centralised medulloblastoma diagnostics von Crosier, S, Hicks, D, Schwalbe, EC, Williamson, D, Nicholson, SL, Smith, A, Lindsey, JC, Michalski, A, Pizer, B, Bailey, S, Bown, N, Cuthbert, G, Wharton, SB, Jacques, TS, Joshi, A, Clifford, SC

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Time, pattern, and outcome of medulloblastoma relapse and their association with tumour biology at diagnosis and therapy: a multicentre cohort study von Hill, RM, Richardson, S, Schwalbe, EC, Hicks, D, Lindsey, JC, Crosier, S, Rafiee, G, Grabovska, Y, Wharton, SB, Jacques, TS, Michalski, A, Joshi, A, Pizer, B, Williamson, D, Bailey, S, Clifford, SC

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The molecular landscape and associated clinical experience in infant medulloblastoma: prognostic significance of second-generation subtypes von Hicks, D, Rafiee, G, Schwalbe, EC, Howell, CI, Lindsey, JC, Hill, RM, Smith, A, Adidharma, P, Steel, C, Richardson, S, Pease, L, Danilenko, M, Crosier, S, Joshi, A, Wharton, S, Jacques, T, Pizer, B, Michalski, A, Williamson, D, Bailey, S, Clifford, SC

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Novel molecular subgroups for clinical classification and outcome prediction in childhood medulloblastoma: a cohort study von Schwalbe, EC, Lindsey, JC, Nakjang, S, Crosier, S, Smith, AJ, Hicks, D, Rafiee, G, Hill, RM, Iliasova, A, Stone, T, Pizer, B, Michalski, A, Joshi, A, Wharton, SB, Jacques, TS, Bailey, S, Williamson, D, Clifford, SC

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Combined MYC and P53 Defects Emerge at Medulloblastoma Relapse and Define Rapidly Progressive, Therapeutically Targetable Disease von Hill, Rebecca M, Kuijper, Sanne, Lindsey, Janet C, Petrie, Kevin, Schwalbe, Ed C, Barker, Karen, Boult, Jessica K. R, Williamson, Daniel, Ahmad, Zai, Hallsworth, Albert, Ryan, Sarra L, Poon, Evon, Robinson, Simon P, Ruddle, Ruth, Raynaud, Florence I, Howell, Louise, Kwok, Colin, Joshi, Abhijit, Nicholson, Sarah Leigh, Crosier, Stephen, Ellison, David W, Wharton, Stephen B, Robson, Keith, Michalski, Antony, Hargrave, Darren, Jacques, Thomas S, Pizer, Barry, Bailey, Simon, Swartling, Fredrik J, Weiss, William A, Chesler, Louis, Clifford, Steven C

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Combined MYC and P53 Defects Emerge at Medulloblastoma Relapse and Define Rapidly Progressive, Therapeutically Targetable Disease von Hill, RM, Kuijper, S, Lindsey, JC, Petrie, K, Schwalbe, EC, Barker, K, Boult, JKR, Williamson, D, Ahmad, Z, Hallsworth, A, Ryan, SL, Poon, E, Robinson, SP, Ruddle, R, Raynaud, FI, Howell, L, Kwok, C, Joshi, A, Nicholson, SL, Crosier, S, Ellison, DW, Wharton, SB, Robson, K, Michalski, A, Hargrave, D, Jacques, TS, Pizer, B, Bailey, S, Swartling, FJ, Weiss, WA, Chesler, L, Clifford, SC

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