Engaging natural killer cells for cancer therapy via NKG2D, CD16A and other receptors von Whalen, Kerry A., Rakhra, Kavya, Mehta, Naveen K., Steinle, Alexander, Michaelson, Jennifer S., Baeuerle, Patrick A.

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Targeting the Somatostatin Receptor 2 with the Miniaturized Drug Conjugate, PEN-221: A Potent and Novel Therapeutic for the Treatment of Small Cell Lung Cancer von Whalen, Kerry A, White, Brian H, Quinn, James M, Kriksciukaite, Kristina, Alargova, Rossitza, Au Yeung, Tsun P, Bazinet, Patrick, Brockman, Adam, DuPont, Michelle M, Oller, Haley, Gifford, James, Lemelin, Charles-Andre, Lim Soo, Patrick, Perino, Samantha, Moreau, Benoît, Sharma, Gitanjali, Shinde, Rajesh, Sweryda-Krawiec, Beata, Bilodeau, Mark T, Wooster, Richard

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Polyomavirus Middle T Antigen Induces the Transcription of Osteopontin, a Gene Important for the Migration of Transformed Cells von WHALEN, Kerry A, WEBER, Georg F, BENJAMIN, Thomas L, SCHAFFHAUSEN, Brian S

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Novel Miniaturized Drug Conjugate Leverages HSP90-driven Tumor Accumulation to Overcome PI3K Inhibitor Delivery Challenges to Solid Tumors von Perino, Samantha, Moreau, Benoit, Freda, Jessica, Cirello, Amanda, White, Brian H., Quinn, James M., Kriksciukaite, Kristina, Someshwar, Ashwajith, Romagnoli, Janel, Robinson, Megan, Movassaghian, Sara, Cipriani, Tyler, Wooster, Richard, Bilodeau, Mark T., Whalen, Kerry A.

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Genetic Analysis of the Polyomavirus DnaJ Domain von WHALEN, Kerry A, DE JESUS, Rowena, KEAN, Jennifer A, SCHAFFHAUSEN, Brian S

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194 Characterization of the pharmacodynamic activity of CLN-619, an anti-MICA/B monoclonal antibody, in patients from an ongoing Phase 1 trial von Shapiro, Irina M, Whalen, Kerry A, Liu, Laura, Liu, Tracy, Michaelson, Jennifer S, Spira, Alexander I, Wang, Judy S, Hamilton, Erika, Millward, Michael, Arance, Ana Maria, Moreno, Victor, Melero, Ignacio, Stec, Rafal, Jones, Jeffrey A

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Abstract 2943: The structural basis for inhibition of MICA shedding and anti-tumor activity of the monoclonal anti-MICA|B antibody, CLN-619 von Whalen, Kerry A., Mehta, Naveen K., Meetze, Kristan, Michaelson, Jennifer S., Baeuerle, Patrick S.

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Abstract 3506: CLN-619, a clinical-stage MICA/MICB-specific IgG1 antibody, restores the MICA/MICB-NKG2D axis to promote NK-mediated tumor cell lysis von Whalen, Kerry A., Mehta, Naveen K., Yalcin, Safak, Meetze, Kristan, Gibson, Neil W., Michaelson, Jennifer S., Baeuerle, Patrick A.

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ANTI-MICA/B ANTIBODIES WITH ENHANCED EFFECTOR FUNCTION AND METHODS OF USE von MICHAELSON, Jennifer S, WHALEN, Kerry A, MEHTA, Naveen K, BAEUERLE, Patrick A

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Discovery of an SSTR2-Targeting Maytansinoid Conjugate (PEN-221) with Potent Activity in Vitro and in Vivo von White, Brian H, Whalen, Kerry, Kriksciukaite, Kristina, Alargova, Rossitza, Au Yeung, Tsun, Bazinet, Patrick, Brockman, Adam, DuPont, Michelle, Oller, Haley, Lemelin, Charles-Andre, Lim Soo, Patrick, Moreau, Benoît, Perino, Samantha, Quinn, James M, Sharma, Gitanjali, Shinde, Rajesh, Sweryda-Krawiec, Beata, Wooster, Richard, Bilodeau, Mark T

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Cervical Cancer Screening by Refugee Category in a Refugee Health Primary Care Clinic in Calgary, Canada, 2011–2016 von Whalen-Browne, Molly, Talavlikar, Rachel, Brown, Garielle, McBrien, Kerry, Wiedmeyer, Mei-ling, Norrie, Eric, Fabreau, Gabriel

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Abstract CT156: Characterization of PEN-866, a Heat Shock Protein 90 (HSP90) binding conjugate of SN-38, in patient plasma and tumors from the first in human study von Thomas, Anish, Kriksciukaite, Kristina, Falchook, Gerald, Bendel, Johanna, Ulahannan, Susanna, Redon, Christophe, Mei, Laura, Whalen, Kerry, Bloss, Jeffrey, Bilodeau, Mark T.

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A phase 1 dose-escalation study to investigate the safety, efficacy, pharmacokinetics, and pharmacodynamic activity of cln-619 (Anti-MICA/B antibody) alone and in combination with... von Wang, Judy S., Gutierrez, Martin, Rasco, Drew W., Melero Bermejo, Ignacio, Powderly, John D., Hamilton, Erika P., Millward, Michael, Arance, Ana Maria, Stec, Rafal, Moreno, Victor, Sharma, Manish, Lugowska, Iwona A., Shackleton, Mark J., Frentzas, Sophia, Janik, John Edward, Liu, Tracy, Shapiro, Irina, Whalen, Kerry, Jones, Jeffrey Alan, Spira, Alexander I.

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Abstract 5806: Combination of the miniature drug conjugate PEN-866 with PARP inhibitors as a rational approach to overcoming limitations of PARP inhibitor monotherapy von Perino, Samantha, Quinn, James M., Callahan, Marrissa, Sharma, Gitanjali, White, Brian, Bilodeau, Mark, Alland, Leila, Whalen, Kerry, Wooster, Richard

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A phase 1 dose-escalation study to investigate the safety, efficacy, pharmacokinetics, and pharmacodynamic activity of CLN-619 (anti-MICA/MICB antibody) alone and in combination wi... von Powderly, John D., Gutierrez, Martin, Wang, Judy S., Hamilton, Erika P., Sharma, Manish, Spira, Alexander I., Millward, Michael, Shackleton, Mark J., Frentzas, Sophia, Koczywas, Marianna, Mehta, Naveen, Christensen, Ann Marie, Shapiro, Irina, Whalen, Kerry, Michaelson, Jennifer, Baeuerle, Patrick, Janik, John Edward, Rasco, Drew W.

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Abstract 4328: Epigenetic modulation of SSTR2 expression provides the potential to broaden PEN-221 treatment population von Perino, Samantha, Quinn, James, Freda, Jessica, White, Brian, Bailey, Scott, Bhatia, Viren, Sweryda-Krawiec, Beata, Bilodeau, Mark, Bloss, Jeffrey D., Whalen, Kerry, Wooster, Richard

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Short-term and Long-term Weight Management Results of a Large Employer-Sponsored Wellness Program von Scoggins, John F., Sakumoto, Karleen N., Schaefer, Kerry S., Bascom, Brooke, Robbins, Donald J., Whalen, Caroline L.

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Abstract 39: Discovery of PEN-221, an SSTR2-targeting maytansinoid conjugate with potent activity in vitro and in vivo von White, Brian H., Bazinet, Patrick, Whalen, Kerry, DuPont, Michelle, Quinn, James M., Alargova, Rossitza, Yeung, Tsun Au, Brockman, Adam, Gifford, James, Oller, Haley, Kriksciukaite, Kristina, Lemelin, Charles-Andre, Soo, Patrick Lim, Moreau, Benoit, Perino, Samantha, Sharma, Gitanjali, Shinde, Rajesh, Sweryda-Krawiec, Beata, Simcox, Mary, Wooster, Richard, Bilodeau, Mark T.

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Abstract CT021: Assessing clinical and pharmacodynamic (PD) profiles of patients (pts) with chronic lymphocytic leukemia (CLL) on ianalumab (VAY736) + ibrutinib von Rogers, Kerry Anne, Yan, Pearlly, Flinn, Ian W., Stephens, Deborah M., Kipps, Thomas J., Larson, Sarah M., Martz, Laura, Chen, Xi, Wang, Huabao, Hopping, Ethan, Bundschuh, Ralf, Acosta, Alexandra, Baldoni, Daniela, Chaudhury, Anwesha, Whalen, Jeanne, Hassounah, Nadia B., Orwitz, Nina, Woo, Janghee, Byrd, John C.

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Enzymatic process for production of improved hop products von BERDAHL DAVID R, BUFFIN BRIAN PATRICK, WILLIAMS KEVIN, JONES, MICHAEL, B, WHALEN KERRY

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