Dynamic Gene Regulatory Networks Drive Hematopoietic Specification and Differentiation von Goode, Debbie K., Obier, Nadine, Vijayabaskar, M.S., Lie-A-Ling, Michael, Lilly, Andrew J., Hannah, Rebecca, Lichtinger, Monika, Batta, Kiran, Florkowska, Magdalena, Patel, Rahima, Challinor, Mairi, Wallace, Kirstie, Gilmour, Jane, Assi, Salam A., Cauchy, Pierre, Hoogenkamp, Maarten, Westhead, David R., Lacaud, Georges, Kouskoff, Valerie, Göttgens, Berthold, Bonifer, Constanze

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Benchmarking pipelines for subclonal deconvolution of bulk tumour sequencing data von Tanner, Georgette, Westhead, David R., Droop, Alastair, Stead, Lucy F.

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Gene-expression profiling of bortezomib added to standard chemoimmunotherapy for diffuse large B-cell lymphoma (REMoDL-B): an open-label, randomised, phase 3 trial von Davies, Andrew, Cummin, Thomas E, Barrans, Sharon, Maishman, Tom, Mamot, Christoph, Novak, Urban, Caddy, Josh, Stanton, Louise, Kazmi-Stokes, Shamim, McMillan, Andrew, Fields, Paul, Pocock, Christopher, Collins, Graham P, Stephens, Richard, Cucco, Francesco, Clipson, Alexandra, Sha, Chulin, Tooze, Reuben, Care, Matthew A, Griffiths, Gareth, Du, Ming-Qing, Westhead, David R, Burton, Catherine, Johnson, Peter W M

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Molecular High-Grade B-Cell Lymphoma: Defining a Poor-Risk Group That Requires Different Approaches to Therapy von Sha, Chulin, Barrans, Sharon, Cucco, Francesco, Bentley, Michael A, Care, Matthew A, Cummin, Thomas, Kennedy, Hannah, Thompson, Joe S, Uddin, Rahman, Worrillow, Lisa, Chalkley, Rebecca, van Hoppe, Moniek, Ahmed, Sophia, Maishman, Tom, Caddy, Josh, Schuh, Anna, Mamot, Christoph, Burton, Catherine, Tooze, Reuben, Davies, Andrew, Du, Ming-Qing, Johnson, Peter W M, Westhead, David R

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Identification of a Dynamic Core Transcriptional Network in t(8;21) AML that Regulates Differentiation Block and Self-Renewal von Ptasinska, Anetta, Assi, Salam A., Martinez-Soria, Natalia, Imperato, Maria Rosaria, Piper, Jason, Cauchy, Pierre, Pickin, Anna, James, Sally R., Hoogenkamp, Maarten, Williamson, Dan, Wu, Mengchu, Tenen, Daniel G., Ott, Sascha, Westhead, David R., Cockerill, Peter N., Heidenreich, Olaf, Bonifer, Constanze

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Transcellular chaperone signaling is an intercellular stress-response distinct from the HSF-1-mediated heat shock response von Miles, Jay, Townend, Sarah, Milonaitytė, Dovilė, Smith, William, Hodge, Francesca, Westhead, David R, van Oosten-Hawle, Patricija

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A microarray platform-independent classification tool for cell of origin class allows comparative analysis of gene expression in diffuse large B-cell lymphoma von Care, Matthew A, Barrans, Sharon, Worrillow, Lisa, Jack, Andrew, Westhead, David R, Tooze, Reuben M

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A primer on learning in Bayesian networks for computational biology von Needham, Chris J, Bradford, James R, Bulpitt, Andrew J, Westhead, David R

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A PQM-1-Mediated Response Triggers Transcellular Chaperone Signaling and Regulates Organismal Proteostasis von O’Brien, Daniel, Jones, Laura M., Good, Sarah, Miles, Jo, Vijayabaskar, M.S., Aston, Rebecca, Smith, Catrin E., Westhead, David R., van Oosten-Hawle, Patricija

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Improved prediction of protein–protein binding sites using a support vector machines approach von Bradford, James R., Westhead, David R.

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Identification of gene specific cis-regulatory elements during differentiation of mouse embryonic stem cells: An integrative approach using high-throughput datasets von Vijayabaskar, M S, Goode, Debbie K, Obier, Nadine, Lichtinger, Monika, Emmett, Amber M L, Abidin, Fatin N Zainul, Shar, Nisar, Hannah, Rebecca, Assi, Salam A, Lie-A-Ling, Michael, Gottgens, Berthold, Lacaud, Georges, Kouskoff, Valerie, Bonifer, Constanze, Westhead, David R

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Differential Efficacy From the Addition of Bortezomib to R-CHOP in Diffuse Large B-Cell Lymphoma According to the Molecular Subgroup in the REMoDL-B Study With a 5-Year Follow-Up von Davies, Andrew J, Barrans, Sharon, Stanton, Louise, Caddy, Josh, Wilding, Sam, Saunders, Geoff, Mamot, Christoph, Novak, Urban, McMillan, Andrew, Fields, Paul, Collins, Graham P, Stephens, Richard, Cucco, Francesco, Sha, Chulin, van Hoppe, Moniek, Tooze, Reuben, Davies, John R, Griffiths, Gareth, Schuh, Anna, Burton, Catherine, Westhead, David R, Du, Ming-Qing, Johnson, Peter W M

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Distinct genetic changes reveal evolutionary history and heterogeneous molecular grade of DLBCL with MYC/BCL2 double-hit von Cucco, Francesco, Barrans, Sharon, Sha, Chulin, Clipson, Alexandra, Crouch, Simon, Dobson, Rachel, Chen, Zi, Thompson, Joe Sneath, Care, Matthew A., Cummin, Thomas, Caddy, Josh, Liu, Hongxiang, Robinson, Anne, Schuh, Anna, Fitzgibbon, Jude, Painter, Daniel, Smith, Alexandra, Roman, Eve, Tooze, Reuben, Burton, Catherine, Davies, Andrew J., Westhead, David R., Johnson, Peter W. M., Du, Ming-Qing

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Simulation of heterogeneous tumour genomes with HeteroGenesis and in silico whole exome sequencing von Tanner, Georgette, Westhead, David R, Droop, Alastair, Stead, Lucy F

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IDHwt glioblastomas can be stratified by their transcriptional response to standard treatment, with implications for targeted therapy von Tanner, Georgette, Barrow, Rhiannon, Ajaib, Shoaib, Al-Jabri, Muna, Ahmed, Nazia, Pollock, Steven, Finetti, Martina, Rippaus, Nora, Bruns, Alexander F, Syed, Khaja, Poulter, James A, Matthews, Laura, Hughes, Thomas, Wilson, Erica, Johnson, Colin, Varn, Frederick S, Brüning-Richardson, Anke, Hogg, Catherine, Droop, Alastair, Gusnanto, Arief, Care, Matthew A, Cutillo, Luisa, Westhead, David R, Short, Susan C, Jenkinson, Michael D, Brodbelt, Andrew, Chakrabarty, Aruna, Ismail, Azzam, Verhaak, Roel G W, Stead, Lucy F

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In vitro generation of long-lived human plasma cells von Cocco, Mario, Stephenson, Sophie, Care, Matthew A, Newton, Darren, Barnes, Nicholas A, Davison, Adam, Rawstron, Andy, Westhead, David R, Doody, Gina M, Tooze, Reuben M

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Chronic FLT3-ITD Signaling in Acute Myeloid Leukemia Is Connected to a Specific Chromatin Signature von Cauchy, Pierre, James, Sally R., Zacarias-Cabeza, Joaquin, Ptasinska, Anetta, Imperato, Maria Rosaria, Assi, Salam A., Piper, Jason, Canestraro, Martina, Hoogenkamp, Maarten, Raghavan, Manoj, Loke, Justin, Akiki, Susanna, Clokie, Samuel J., Richards, Stephen J., Westhead, David R., Griffiths, Michael J., Ott, Sascha, Bonifer, Constanze, Cockerill, Peter N.

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Network Analysis Identifies Proinflammatory Plasma Cell Polarization for Secretion of ISG15 in Human Autoimmunity von Care, Matthew A, Stephenson, Sophie J, Barnes, Nicholas A, Fan, Im, Zougman, Alexandre, El-Sherbiny, Yasser M, Vital, Edward M, Westhead, David R, Tooze, Reuben M, Doody, Gina M

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The Role of SurA PPIase Domains in Preventing Aggregation of the Outer-Membrane Proteins tOmpA and OmpT von Humes, Julia R., Schiffrin, Bob, Calabrese, Antonio N., Higgins, Anna J., Westhead, David R., Brockwell, David J., Radford, Sheena E.

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Bridging the gap with the UK Genomics Pathology Imaging Collection von Jennings, Charlotte N., Humphries, Matthew P., Wood, Suzanne, Jadhav, Monit, Chabra, Robbie, Brown, Christopher, Chan, Georgia, Kaye, Danny, Bansal, Daljeet, Colquhoun, Catherine, Merzouki, Nour, Arumugam, Prabhu, Westhead, David R., Treanor, Darren

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