Male LH-Independent Sexual Precocity in a 3.5-Year-Old Boy Caused by a Somatic Activating Mutation of the LH Receptor in a Leydig Cell Tumor von Richter-Unruh, A, Wessels, H T, Menken, U, Bergmann, M, Schmittmann-Ohters, K, Schaper, J, Tappeser, S, Hauffa, B P

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In vitro secretion of FSH by cultured clinically nonfunctioning and gonadotroph pituitary adenomas is directly correlated with locally produced levels of activin A von Wessels, H. T., Hofland, L. J., Van Der Wal, R., Van Gastel, L., Van Koetsveld, P. M., De Herder, W. W., De Jong, F. H.

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Bragatston study protocol: a multicentre cohort study on automated quantification of cardiovascular calcifications on radiotherapy planning CT scans for cardiovascular risk predict... von Emaus, Marleen J, Išgum, Ivana, van Velzen, Sanne G M, van den Bongard, H J G Desirée, Gernaat, Sofie A M, Lessmann, Nikolas, Sattler, Margriet G A, Teske, Arco J, Penninkhof, Joan, Meijer, Hanneke, Pignol, Jean-Philippe, Verkooijen, Helena M

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Male LH-Independent Sexual Precocity in a 3.5-Year-Old Boy Caused by a Somatic Activating Mutation of the LH Receptor in a Leydig Cell Tumor von Richter-Unruh, A., Wessels, H. T., Menken, U., Bergmann, M., Schmittmann-Ohters, K., Schaper, J., Tappeser, S., Hauffa, B. P.

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Colorectal cancer intrinsic subtypes predict chemotherapy benefit, deficient mismatch repair and epithelial‐to‐mesenchymal transition von Roepman, Paul, Schlicker, Andreas, Tabernero, Josep, Majewski, Ian, Tian, Sun, Moreno, Victor, Snel, Mireille H, Chresta, Christine M, Rosenberg, Robert, Nitsche, Ulrich, Macarulla, Teresa, Capella, Gabriel, Salazar, Ramon, Orphanides, George, Wessels, Lodewyk FA, Bernards, Rene, Simon, Iris M

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MED12 Controls the Response to Multiple Cancer Drugs through Regulation of TGF-β Receptor Signaling von Huang, Sidong, Hölzel, Michael, Knijnenburg, Theo, Schlicker, Andreas, Roepman, Paul, McDermott, Ultan, Garnett, Mathew, Grernrum, Wipawadee, Sun, Chong, Prahallad, Anirudh, Groenendijk, Floris H., Mittempergher, Lorenza, Nijkamp, Wouter, Neefjes, Jacques, Salazar, Ramon, ten Dijke, Peter, Uramoto, Hidetaka, Tanaka, Fumihiro, Beijersbergen, Roderick L., Wessels, Lodewyk F.A., Bernards, René

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Recent insights in the pharmacological actions of methotrexate in the treatment of rheumatoid arthritis von Wessels, J. A. M., Huizinga, T. W. J., Guchelaar, H.-J.

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Breast cancer subtyping by immunohistochemistry and histological grade outperforms breast cancer intrinsic subtypes in predicting neoadjuvant chemotherapy response von Lips, E. H., Mulder, L., de Ronde, J. J., Mandjes, I. A. M., Koolen, B. B., Wessels, L. F. A., Rodenhuis, S., Wesseling, J.

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Purification of cross-linked RNA-protein complexes by phenol-toluol extraction von Urdaneta, Erika C., Vieira-Vieira, Carlos H., Hick, Timon, Wessels, Hans-Herrmann, Figini, Davide, Moschall, Rebecca, Medenbach, Jan, Ohler, Uwe, Granneman, Sander, Selbach, Matthias, Beckmann, Benedikt M.

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An aCGH classifier derived from BRCA1-mutated breast cancer and benefit of high-dose platinum-based chemotherapy in HER2-negative breast cancer patients von Vollebergh, M.A., Lips, E.H., Nederlof, P.M., Wessels, L.F.A., Schmidt, M.K., van Beers, E.H., Cornelissen, S., Holtkamp, M., Froklage, F.E., de Vries, E.G.E., Schrama, J.G., Wesseling, J., van de Vijver, M.J., van Tinteren, H., de Bruin, M., Hauptmann, M., Rodenhuis, S., Linn, S.C.

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Somatic loss of BRCA1 and p53 in mice induces mammary tumors with features of human BRCA1-mutated basal-like breast cancer von Liu, Xiaoling, Holstege, Henne, van der Gulden, Hanneke, Treur-Mulder, Marcelle, Zevenhoven, John, Velds, Arno, Kerkhoven, Ron M, van Vliet, Martin H, Wessels, Lodewyk F.A, Peterse, Johannes L, Berns, Anton, Jonkers, Jos

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The role of neutrophils in immune dysfunction during severe inflammation von Leliefeld, Pieter H C, Wessels, Catharina M, Leenen, Luke P H, Koenderman, Leo, Pillay, Janesh

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Membrane fouling and process performance of forward osmosis membranes on activated sludge von Cornelissen, E.R., Harmsen, D., de Korte, K.F., Ruiken, C.J., Qin, Jian-Jun, Oo, H., Wessels, L.P.

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Genomic patterns resembling BRCA1- and BRCA2-mutated breast cancers predict benefit of intensified carboplatin-based chemotherapy von Vollebergh, Marieke A, Lips, Esther H, Nederlof, Petra M, Wessels, Lodewyk F A, Wesseling, Jelle, Vd Vijver, Marc J, de Vries, Elisabeth G E, van Tinteren, Harm, Jonkers, Jos, Hauptmann, Michael, Rodenhuis, Sjoerd, Linn, Sabine C

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Immune induction strategies in metastatic triple-negative breast cancer to enhance the sensitivity to PD-1 blockade: the TONIC trial von Voorwerk, Leonie, Slagter, Maarten, Horlings, Hugo M., Sikorska, Karolina, van de Vijver, Koen K., de Maaker, Michiel, Nederlof, Iris, Kluin, Roelof J. C., Warren, Sarah, Ong, SuFey, Wiersma, Terry G., Russell, Nicola S., Lalezari, Ferry, Schouten, Philip C., Bakker, Noor A. M., Ketelaars, Steven L. C., Peters, Dennis, Lange, Charlotte A. H., van Werkhoven, Erik, van Tinteren, Harm, Mandjes, Ingrid A. M., Kemper, Inge, Onderwater, Suzanne, Chalabi, Myriam, Wilgenhof, Sofie, Haanen, John B. A. G., Salgado, Roberto, de Visser, Karin E., Sonke, Gabe S., Wessels, Lodewyk F. A., Linn, Sabine C., Schumacher, Ton N., Blank, Christian U., Kok, Marleen

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Insertional mutagenesis identifies multiple networks of cooperating genes driving intestinal tumorigenesis von March, H Nikki, Rust, Alistair G, Wright, Nicholas A, ten Hoeve, Jelle, de Ridder, Jeroen, Eldridge, Matthew, van der Weyden, Louise, Berns, Anton, Gadiot, Jules, Uren, Anthony, Kemp, Richard, Arends, Mark J, Wessels, Lodewyk F A, Winton, Douglas J, Adams, David J

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Chemically triggered drug release from an antibody-drug conjugate leads to potent antitumour activity in mice von Rossin, Raffaella, Versteegen, Ron M., Wu, Jeremy, Khasanov, Alisher, Wessels, Hans J., Steenbergen, Erik J., ten Hoeve, Wolter, Janssen, Henk M., van Onzen, Arthur H. A. M., Hudson, Peter J., Robillard, Marc S.

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Loss of androgen receptor signaling in prostate cancer‐associated fibroblasts (CAFs) promotes CCL2‐ and CXCL8‐mediated cancer cell migration von Cioni, Bianca, Nevedomskaya, Ekaterina, Melis, Monique H. M., Burgsteden, Johan, Stelloo, Suzan, Hodel, Emma, Spinozzi, Daniele, Jong, Jeroen, der Poel, Henk, Boer, Jan Paul, Wessels, Lodewyk F. A., Zwart, Wilbert, Bergman, Andries M.

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Placental syncytium forms a biophysical barrier against pathogen invasion von Zeldovich, Varvara B, Clausen, Casper H, Bradford, Emily, Fletcher, Daniel A, Maltepe, Emin, Robbins, Jennifer R, Bakardjiev, Anna I

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CYP2D6 genotype in relation to tamoxifen efficacy in a Dutch cohort of the tamoxifen exemestane adjuvant multinational (TEAM) trial von Dezentjé, V. O., van Schaik, R. H. N., Vletter-Bogaartz, J. M., van der Straaten, T., Wessels, J. A. M., Kranenbarg, E. M.-K., Berns, E. M., Seynaeve, C., Putter, H., van de Velde, C. J. H., Nortier, J. W. R., Gelderblom, H., Guchelaar, H.-J.

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