The human anti-CD40 agonist antibody mitazalimab (ADC-1013; JNJ-64457107) activates antigen-presenting cells, improves expansion of antigen-specific T cells, and enhances anti-tumo... von Deronic, Adnan, Nilsson, Anneli, Thagesson, Mia, Werchau, Doreen, Enell Smith, Karin, Ellmark, Peter

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The CTLA-4 x OX40 bispecific antibody ATOR-1015 induces anti-tumor effects through tumor-directed immune activation von Kvarnhammar, Anne Månsson, Veitonmäki, Niina, Hägerbrand, Karin, Dahlman, Anna, Smith, Karin Enell, Fritzell, Sara, von Schantz, Laura, Thagesson, Mia, Werchau, Doreen, Smedenfors, Kristine, Johansson, Maria, Rosén, Anna, Åberg, Ida, Winnerstam, Magnus, Nyblom, Eva, Barchan, Karin, Furebring, Christina, Norlén, Per, Ellmark, Peter

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Bispecific antibodies targeting CD40 and tumor-associated antigens promote cross-priming of T cells resulting in an antitumor response superior to monospecific antibodies von Hägerbrand, Karin, Varas, Laura, Deronic, Adnan, Nyesiga, Barnabas, Sundstedt, Anette, Ljung, Lill, Sakellariou, Christina, Werchau, Doreen, Thagesson, Mia, Gomez Jimenez, David, Greiff, Lennart, Celander, Mona, Smedenfors, Kristine, Rosén, Anna, Bölükbas, Deniz, Carlsson, Fredrika, Levin, Mattias, Säll, Anna, von Schantz, Laura, Lindstedt, Malin, Ellmark, Peter

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751 Neo-X-Prime bispecific antibodies targeting CD40 and tumor antigens promote cross-presentation of tumor exosome-derived neoantigen and induce superior anti-tumor responses comp... von Hagerbrand, Karin, Levin, Mattias, Schantz, Laura Von, Varas, Laura, Säll, Anna, Deronic, Adnan, Sundstedt, Anette, Ljung, Lill, Barchan, Karin, Werchau, Doreen, Rosén, Anna, Nyesiga, Barnabas, Lindqvist, Eva, Thagesson, Mia, Ellmark, Peter

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858 A bispecific antibody targeting CD40 and EpCAM induces superior anti-tumor effects compared to the combination of the monospecific antibodies von Ellmark, Peter, Hägerbrand, Karin, Levin, Mattias, Schantz, Laura Von, Deronic, Adnan, Varas, Laura, Säll, Anna, Barchan, Karin, Werchau, Doreen, Ljug, Lill, Thageson, Mia, Rosen, Anna, Sakellariou, Christina, Lindstedt, Malin

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The Bispecific Tumor Antigen-Conditional 4-1BB x 5T4 Agonist, ALG.APV-527, Mediates Strong T-Cell Activation and Potent Antitumor Activity in Preclinical Studies von Nelson, Michelle H, Fritzell, Sara, Miller, Robert, Werchau, Doreen, Van Citters, Danielle, Nilsson, Anneli, Misher, Lynda, Ljung, Lill, Bader, Robert, Deronic, Adnan, Chunyk, Allison G, Schultz, Lena, Varas, Laura A, Rose, Nadia, Håkansson, Maria, Gross, Jane, Furebring, Christina, Pavlik, Peter, Sundstedt, Anette, Veitonmäki, Niina, Ramos, Hilario J, Säll, Anna, Dahlman, Anna, Bienvenue, David, von Schantz, Laura, McMahan, Catherine J, Askmyr, Maria, Hernandez-Hoyos, Gabriela, Ellmark, Peter

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Abstract 4155: Mitazalimab, a potent CD40 agonist in combination with chemotherapy redirects and activates tumor infiltrating myeloid cells von Smith, Karin Enell, Thagesson, Mia, Nilsson, Anneli, Werchau, Doreen, Ellmark, Peter

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Abstract 3623: The CTLA-4 x OX40 bispecific antibody ATOR-1015 induces anti-tumor effects through tumor-directed immune activation von Veitonmäki, Niina, Thagesson, Mia, Werchau, Doreen, Hägerbrand, Karin, Smedenfors, Kristine, Månsson-Kvarnhammar, Anne, Rosén, Anna, Johansson, Maria, Furebring, Christina, Norlén, Per, Ellmark, Peter

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Abstract 2380: Preclinical safety and efficacy of a tumor-directed T cell activating 4-1BB x 5T4 ADAPTIR™ bispecific antibody von Dahlman, Anna, Nelson, Michelle, Bannink, Jeannette, Johnson, Starrla, Werchau, Doreen, Nilsson, Anneli, Ljung, Lill, Blahnik-Fagan, Gabriele, Bader, Robert, Deronic, Adnan, Ellmark, Peter, Askmyr, Maria, Hernandez-Hoyos, Gabriela, McMahan, Cathy, Fritzell, Sara

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Abstract 695: The generation of a mono-selective CDK7 inhibitor von Eickhoff, Jan E., Zischinsky, Gunther, Choidas, Axel, Habenberger, Peter, Wolf, Alexander, Degenhardt, Carsten, Baumann, Matthias, Unger, Anke, Ghallab, Ahmad, Werchau, Doreen, Hengstler, Jan, Nussbaumer, Peter, Klebl, Bert M.

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