Mutant Huntingtin Disrupts the Nuclear Pore Complex von Grima, Jonathan C., Daigle, J. Gavin, Arbez, Nicolas, Cunningham, Kathleen C., Zhang, Ke, Ochaba, Joseph, Geater, Charlene, Morozko, Eva, Stocksdale, Jennifer, Glatzer, Jenna C., Pham, Jacqueline T., Ahmed, Ishrat, Peng, Qi, Wadhwa, Harsh, Pletnikova, Olga, Troncoso, Juan C., Duan, Wenzhen, Snyder, Solomon H., Ranum, Laura P.W., Thompson, Leslie M., Lloyd, Thomas E., Ross, Christopher A., Rothstein, Jeffrey D.

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Non-contrast assessment of blood-brain barrier permeability to water in mice: An arterial spin labeling study at cerebral veins von Wei, Zhiliang, Liu, Hongshuai, Lin, Zixuan, Yao, Minmin, Li, Ruoxuan, Liu, Chang, Li, Yuguo, Xu, Jiadi, Duan, Wenzhen, Lu, Hanzhang

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A novel and accurate full-length HTT mouse model for Huntington's disease von Shenoy, Sushila A, Zheng, Sushuang, Liu, Wencheng, Dai, Yuanyi, Liu, Yuanxiu, Hou, Zhipeng, Mori, Susumu, Tang, Yi, Cheng, Jerry, Duan, Wenzhen, Li, Chenjian

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Early detection of Alzheimer's disease using creatine chemical exchange saturation transfer magnetic resonance imaging von Chen, Lin, van Zijl, Peter C.M., Wei, Zhiliang, Lu, Hanzhang, Duan, Wenzhen, Wong, Philip C., Li, Tong, Xu, Jiadi

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Toward accurate cerebral blood flow estimation in mice after accounting for anesthesia von Wei, Zhiliang, Li, Yuguo, Bibic, Adnan, Duan, Wenzhen, Xu, Jiadi, Lu, Hanzhang

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Senolytic therapy preserves blood-brain barrier integrity and promotes microglia homeostasis in a tauopathy model von Yao, Minmin, Wei, Zhiliang, Nielsen, Jonathan Scharff, Ouyang, Yuxiao, Kakazu, Aaron, Wang, Haitong, Du, Lida, Li, Ruoxuan, Chu, Tiffany, Scafidi, Susanna, Lu, Hanzhang, Aggarwal, Manisha, Duan, Wenzhen

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Evidence that brain‐derived neurotrophic factor is required for basal neurogenesis and mediates, in part, the enhancement of neurogenesis by dietary restriction in the hippocampus... von Lee, Jaewon, Duan, Wenzhen, Mattson, Mark P.

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Characterization of Behavioral, Neuropathological, Brain Metabolic and Key Molecular Changes in zQ175 Knock-In Mouse Model of Huntington's Disease von Peng, Qi, Wu, Bin, Jiang, Mali, Jin, Jing, Hou, Zhipeng, Zheng, Jennifer, Zhang, Jiangyang, Duan, Wenzhen

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Leptin-mediated Cell Survival Signaling in Hippocampal Neurons Mediated by JAK STAT3 and Mitochondrial Stabilization von Guo, Zhihong, Jiang, Haiyang, Xu, Xiangru, Duan, Wenzhen, Mattson, Mark P.

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Neuroprotective role of Sirt1 in mammalian models of Huntington's disease through activation of multiple Sirt1 targets von Jiang, Mali, Wang, Jiawei, Fu, Jinrong, Du, Lin, Jeong, Hyunkyung, West, Tim, Xiang, Lan, Peng, Qi, Hou, Zhipeng, Cai, Huan, Seredenina, Tamara, Arbez, Nicolas, Zhu, Shanshan, Sommers, Katherine, Qian, Jennifer, Zhang, Jiangyang, Mori, Susumu, Yang, X William, Tamashiro, Kellie L K, Aja, Susan, Moran, Timothy H, Luthi-Carter, Ruth, Martin, Bronwen, Maudsley, Stuart, Mattson, Mark P, Cichewicz, Robert H, Ross, Christopher A, Holtzman, David M, Krainc, Dimitri, Duan, Wenzhen

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Early white matter abnormalities, progressive brain pathology and motor deficits in a novel knock-in mouse model of Huntington's disease von Jin, Jing, Peng, Qi, Hou, Zhipeng, Jiang, Mali, Wang, Xin, Langseth, Abraham J, Tao, Michael, Barker, Peter B, Mori, Susumu, Bergles, Dwight E, Ross, Christopher A, Detloff, Peter J, Zhang, Jiangyang, Duan, Wenzhen

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The antidepressant sertraline improves the phenotype, promotes neurogenesis and increases BDNF levels in the R6/2 Huntington's disease mouse model von Peng, Qi, Masuda, Naoki, Jiang, Mali, Li, Qing, Zhao, Ming, Ross, Christopher A., Duan, Wenzhen

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Dietary restriction and 2-deoxyglucose administration improve behavioral outcome and reduce degeneration of dopaminergic neurons in models of Parkinson's disease von Duan, Wenzhen, Mattson, Mark P.

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Interrogation of brain miRNA and mRNA expression profiles reveals a molecular regulatory network that is perturbed by mutant huntingtin von Jin, Jing, Cheng, Yong, Zhang, Yongqing, Wood, William, Peng, Qi, Hutchison, Emmette, Mattson, Mark P., Becker, Kevin G., Duan, Wenzhen

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Striatal neuronal loss correlates with clinical motor impairment in Huntington's disease von Guo, Zhihong, Rudow, Gay, Pletnikova, Olga, Codispoti, Kari-Elise, Orr, Brent A., Crain, Barbara J., Duan, Wenzhen, Margolis, Russell L., Rosenblatt, Adam, Ross, Christopher A., Troncoso, Juan C.

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Modification of Brain Aging and Neurodegenerative Disorders by Genes, Diet, and Behavior von Mattson, Mark P, Chan, Sic L, Duan, Wenzhen

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Metformin Protects Cells from Mutant Huntingtin Toxicity Through Activation of AMPK and Modulation of Mitochondrial Dynamics von Jin, Jing, Gu, Hao, Anders, Nicole M., Ren, Tianhua, Jiang, Mali, Tao, Michael, Peng, Qi, Rudek, Michelle A., Duan, Wenzhen

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Meal size and frequency affect neuronal plasticity and vulnerability to disease: cellular and molecular mechanisms von Mattson, Mark P., Duan, Wenzhen, Guo, Zhihong

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Dietary restriction normalizes glucose metabolism and BDNF levels, slows disease progression, and increases survival in huntingtin mutant mice von Duan, W, Guo, Z, Jiang, H, Ware, M, Li, X.J, Mattson, M.P

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Targeting Sirtuin-1 in Huntington’s Disease: Rationale and Current Status von Duan, Wenzhen

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