Spectrum and Degree of CDK Drug Interactions Predicts Clinical Performance von Chen, Ping, Lee, Nathan V, Hu, Wenyue, Xu, Meirong, Ferre, Rose Ann, Lam, Hieu, Bergqvist, Simon, Solowiej, James, Diehl, Wade, He, You-Ai, Yu, Xiu, Nagata, Asako, VanArsdale, Todd, Murray, Brion W

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Rapid identification of magnesium ascorbyl phosphate utilizing phosphatase through a chromogenic change-coupled activity assay von Wang, Yuli, Hu, Wenyue, Deng, Zixin, He, Xinyi

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PF-06463922, an ALK/ROS1 Inhibitor, Overcomes Resistance to First and Second Generation ALK Inhibitors in Preclinical Models von Zou, Helen Y., Friboulet, Luc, Kodack, David P., Engstrom, Lars D., Li, Qiuhua, West, Melissa, Tang, Ruth W., Wang, Hui, Tsaparikos, Konstantinos, Wang, Jinwei, Timofeevski, Sergei, Katayama, Ryohei, Dinh, Dac M., Lam, Hieu, Lam, Justine L., Yamazaki, Shinji, Hu, Wenyue, Patel, Bhushankumar, Bezwada, Divya, Frias, Rosa L., Lifshits, Eugene, Mahmood, Sidra, Gainor, Justin F., Affolter, Timothy, Lappin, Patrick B., Gukasyan, Hovhannes, Lee, Nathan, Deng, Shibing, Jain, Rakesh K., Johnson, Ted W., Shaw, Alice T., Fantin, Valeria R., Smeal, Tod

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Rational design and fabrication of monophasic bioceramic microspheres with enhanced mechanical and biological performances in reconstruction of segmental bone defect von Cong, Yu, Liang, Zhong, Jianping, Ni, Wenyue, Hu, Prince, Ghamor-Amegavi Edem, Zhang, Xiangfeng

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PF-06463922 is a potent and selective next-generation ROS1/ALK inhibitor capable of blocking crizotinib-resistant ROS1 mutations von Zou, Helen Y., Li, Qiuhua, Engstrom, Lars D., West, Melissa, Appleman, Vicky, Wong, Katy A., McTigue, Michele, Deng, Ya-Li, Liu, Wei, Brooun, Alexei, Timofeevski, Sergei, McDonnell, Scott R. P., Jiang, Ping, Falk, Matthew D., Lappin, Patrick B., Affolter, Timothy, Nichols, Tim, Hu, Wenyue, Lam, Justine, Johnson, Ted W., Smeal, Tod, Charest, Al, Fantin, Valeria R.

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Integration of single-cell sequencing with machine learning and Mendelian randomization analysis identifies the NAP1L1 gene as a predictive biomarker for Alzheimer's disease von Chen, Runming, Xie, Yujun, Chang, Ze, Hu, Wenyue, Han, Zhenyun

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Distraction or motivation? Unraveling the role of fear of missing out on college students' learning engagement von Kong, Lingfang, Sun, Hui, He, Wenguang, Hu, Wenyue

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Facile synthesis of layered Zn2SnO4/graphene nanohybrid by a one-pot route and its application as high-performance anode for Li-ion batteries von Song, Wentao, Xie, Jian, Hu, Wenyue, Liu, Shuangyu, Cao, Gaoshao, Zhu, Tiejun, Zhao, Xinbing

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Induction of Cyp1a1 Is a Nonspecific Biomarker of Aryl Hydrocarbon Receptor Activation: Results of Large Scale Screening of Pharmaceuticals and Toxicants in Vivo and in Vitro von Hu, Wenyue, Sorrentino, Claudio, Denison, Michael S, Kolaja, Kyle, Fielden, Mark R

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Design and Synthesis of Pyridone-Containing 3,4-Dihydroisoquinoline-1(2H)‑ones as a Novel Class of Enhancer of Zeste Homolog 2 (EZH2) Inhibitors von Kung, Pei-Pei, Rui, Eugene, Bergqvist, Simon, Bingham, Patrick, Braganza, John, Collins, Michael, Cui, Mei, Diehl, Wade, Dinh, Dac, Fan, Connie, Fantin, Valeria R, Gukasyan, Hovhannes J, Hu, Wenyue, Huang, Buwen, Kephart, Susan, Krivacic, Cody, Kumpf, Robert A, Li, Gary, Maegley, Karen A, McAlpine, Indrawan, Nguyen, Lisa, Ninkovic, Sacha, Ornelas, Martha, Ryskin, Michael, Scales, Stephanie, Sutton, Scott, Tatlock, John, Verhelle, Dominique, Wang, Fen, Wells, Peter, Wythes, Martin, Yamazaki, Shinji, Yip, Brian, Yu, Xiu, Zehnder, Luke, Zhang, Wei-Guo, Rollins, Robert A, Edwards, Martin

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Inhibitory effect of polysaccharide of Sargassum weizhouense on PCV2 induced inflammation in mice by suppressing histone acetylation von Hai-lan, Chen, Hong-lian, Tan, Jian, Yang, Manling, Song, Heyu, Feng, Na, Kuang, Wenyue, Hu, Si-yu, Chen, Ying-yi, Wei, Ting-jun, Hu

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Binding of perfluorinated fatty acids to serum proteins von Jones, Paul D., Hu, Wenyue, De Coen, Wim, Newsted, John L., Giesy, John P.

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Enzymolytic soybean meal-impact on growth performance, nutrient digestibility, antioxidative capacity, and intestinal health of weaned piglets von Tan, Kai, Bian, Zhiyao, Liang, Huiqing, Hu, Wenyue, Xia, Miao, Han, Shuaijuan, Chen, Baojiang

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A physiological model of granulopoiesis to predict clinical drug induced neutropenia from in vitro bone marrow studies: with application to a cell cycle inhibitor von Chen, Wenbo, Boras, Britton, Sung, Tae, Yu, Yanke, Zheng, Jenny, Wang, Diane, Hu, Wenyue, Spilker, Mary E., D’Argenio, David Z.

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Mitotic Checkpoint Kinase Mps1 Has a Role in Normal Physiology which Impacts Clinical Utility von Martinez, Ricardo, Blasina, Alessandra, Hallin, Jill F, Hu, Wenyue, Rymer, Isha, Fan, Jeffery, Hoffman, Robert L, Murphy, Sean, Marx, Matthew, Yanochko, Gina, Trajkovic, Dusko, Dinh, Dac, Timofeevski, Sergei, Zhu, Zhou, Sun, Peiquing, Lappin, Patrick B, Murray, Brion W

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Evaluation of miR-216a and miR-217 as Potential Biomarkers of Acute Exocrine Pancreatic Toxicity in Rats von Wang, Jianying, Huang, Wenhu, Thibault, Stephane, Brown, Thomas P., Bobrowski, Walter, Gukasyan, Hovhannes J., Evering, Winston, Hu, Wenyue, John-Baptiste, Annette, Vitsky, Allison

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A whole‐body circulatory neutrophil model with application to predicting clinical neutropenia from in vitro studies von Chen, Wenbo, Boras, Britton, Sung, Tae, Hu, Wenyue, Spilker, Mary E., D’Argenio, David Z.

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Crizotinib reduces the rate of dark adaptation in the rat retina independent of ALK inhibition von Liu, Chang-Ning, Mathialagan, Nagappan, Lappin, Patrick, Fortner, Jay, Somps, Chris, Seitis, Gary, Johnson, Theodore R, Hu, Wenyue, Matsumoto, Diane

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Mechanistic investigation of imatinib-induced cardiac toxicity and the involvement of c-Abl kinase von Hu, Wenyue, Lu, Shuyan, McAlpine, Indrawan, Jamieson, Joseph D, Lee, Dong U, Marroquin, Lisa D, Heyen, Jonathan R, Jessen, Bart A

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Discovery of Aryloxy Tetramethylcyclobutanes as Novel Androgen Receptor Antagonists von Guo, Chuangxing, Linton, Angelica, Kephart, Susan, Ornelas, Martha, Pairish, Mason, Gonzalez, Javier, Greasley, Samantha, Nagata, Asako, Burke, Benjamin J, Edwards, Martin, Hosea, Natilie, Kang, Ping, Hu, Wenyue, Engebretsen, Jon, Briere, David, Shi, Manli, Gukasyan, Hovik, Richardson, Paul, Dack, Kevin, Underwood, Toby, Johnson, Patrick, Morell, Andrew, Felstead, Robert, Kuruma, Hidetoshi, Matsimoto, Hiroaki, Zoubeidi, Amina, Gleave, Martin, Los, Gerrit, Fanjul, Andrea N

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