Probabilistic cell-type assignment of single-cell RNA-seq for tumor microenvironment profiling von Zhang, Allen W., O’Flanagan, Ciara, Chavez, Elizabeth A., Lim, Jamie L. P., Ceglia, Nicholas, McPherson, Andrew, Wiens, Matt, Walters, Pascale, Chan, Tim, Hewitson, Brittany, Lai, Daniel, Mottok, Anja, Sarkozy, Clementine, Chong, Lauren, Aoki, Tomohiro, Wang, Xuehai, Weng, Andrew P, McAlpine, Jessica N., Aparicio, Samuel, Steidl, Christian, Campbell, Kieran R., Shah, Sohrab P.

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TBL1XR1 Mutations Drive Extranodal Lymphoma by Inducing a Pro-tumorigenic Memory Fate von Venturutti, Leandro, Teater, Matt, Zhai, Andrew, Chadburn, Amy, Babiker, Leena, Kim, Daleum, Béguelin, Wendy, Lee, Tak C., Kim, Youngjun, Chin, Christopher R., Yewdell, William T., Raught, Brian, Phillip, Jude M., Jiang, Yanwen, Staudt, Louis M., Green, Michael R., Chaudhuri, Jayanta, Elemento, Olivier, Farinha, Pedro, Weng, Andrew P., Nissen, Michael D., Steidl, Christian, Morin, Ryan D., Scott, David W., Privé, Gilbert G., Melnick, Ari M.

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Single-cell profiling reveals the importance of CXCL13/CXCR5 axis biology in lymphocyte-rich classic Hodgkin lymphoma von Aoki, Tomohiro, Chong, Lauren C., Takata, Katsuyoshi, Milne, Katy, Marshall, Ashley, Chavez, Elizabeth A., Miyata-Takata, Tomoko, Ben-Neriah, Susana, Unrau, Doria, Telenius, Adele, Boyle, Merrill, Weng, Andrew P., Savage, Kerry J., Scott, David W., Farinha, Pedro, Shah, Sohrab P., Nelson, Brad H., Steidl, Christian

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Whole transcriptome sequencing reveals recurrent NOTCH1 mutations in mantle cell lymphoma von Kridel, Robert, Meissner, Barbara, Rogic, Sanja, Boyle, Merrill, Telenius, Adele, Woolcock, Bruce, Gunawardana, Jay, Jenkins, Catherine E., Cochrane, Chris, Ben-Neriah, Susana, Tan, King, Morin, Ryan D., Opat, Stephen, Sehn, Laurie H., Connors, Joseph M., Marra, Marco A., Weng, Andrew P., Steidl, Christian, Gascoyne, Randy D.

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IGF1R Derived PI3K/AKT Signaling Maintains Growth in a Subset of Human T-Cell Acute Lymphoblastic Leukemias von Gusscott, Samuel, Jenkins, Catherine E, Lam, Sonya H, Giambra, Vincenzo, Pollak, Michael, Weng, Andrew P

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Focused chemical genomics using zebrafish xenotransplantation as a pre-clinical therapeutic platform for T-cell acute lymphoblastic leukemia von Bentley, Victoria L, Veinotte, Chansey J, Corkery, Dale P, Pinder, Jordan B, LeBlanc, Marissa A, Bedard, Karen, Weng, Andrew P, Berman, Jason N, Dellaire, Graham

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NOTCH1 Directly Regulates c-MYC and Activates a Feed-Forward-Loop Transcriptional Network Promoting Leukemic Cell Growth von Palomero, Teresa, Lim, Wei Keat, Odom, Duncan T., Sulis, Maria Luisa, Real, Pedro J., Margolin, Adam, Barnes, Kelly C., O'Neil, Jennifer, Neuberg, Donna, Weng, Andrew P., Aster, Jon C., Sigaux, Francois, Soulier, Jean, Look, A. Thomas, Young, Richard A., Califano, Andrea, Ferrando, Adolfo A.

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Single-cell profiling reveals a memory B cell-like subtype of follicular lymphoma with increased transformation risk von Wang, Xuehai, Nissen, Michael, Gracias, Deanne, Kusakabe, Manabu, Simkin, Guillermo, Jiang, Aixiang, Duns, Gerben, Sarkozy, Clementine, Hilton, Laura, Chavez, Elizabeth A., Segat, Gabriela C., Wong, Rachel, Kim, Jubin, Aoki, Tomohiro, Islam, Rashedul, May, Christina, Hung, Stacy, Tyshchenko, Kate, Brinkman, Ryan R., Hirst, Martin, Karsan, Aly, Freeman, Ciara, Sehn, Laurie H., Morin, Ryan D., Roth, Andrew J., Savage, Kerry J., Craig, Jeffrey W., Shah, Sohrab P., Steidl, Christian, Scott, David W., Weng, Andrew P.

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Fanconi-BRCA pathway mutations in childhood T-cell acute lymphoblastic leukemia von Pouliot, Gayle P, Degar, James, Hinze, Laura, Kochupurakkal, Bose, Vo, Chau D, Burns, Melissa A, Moreau, Lisa, Ganesa, Chirag, Roderick, Justine, Peirs, Sofie, Menten, Bjorn, Loh, Mignon L, Hunger, Stephen P, Silverman, Lewis B, Harris, Marian H, Stevenson, Kristen E, Weinstock, David M, Weng, Andrew P, Van Vlierberghe, Pieter, D'Andrea, Alan D, Gutierrez, Alejandro

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Synthetic modeling reveals HOXB genes are critical for the initiation and maintenance of human leukemia von Kusakabe, Manabu, Sun, Ann Chong, Tyshchenko, Kateryna, Wong, Rachel, Nanda, Aastha, Shanna, Claire, Gusscott, Samuel, Chavez, Elizabeth A., Lorzadeh, Alireza, Zhu, Alice, Hill, Ainsleigh, Hung, Stacy, Brown, Scott, Babaian, Artem, Wang, Xuehai, Holt, Robert A., Steidl, Christian, Karsan, Aly, Humphries, R. Keith, Eaves, Connie J., Hirst, Martin, Weng, Andrew P.

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Targeting Leukemia-Initiating Cells in Acute Lymphoblastic Leukemia von Tamiro, Francesco, Weng, Andrew P., Giambra, Vincenzo

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Single Cell Phenotypic Profiling of 27 DLBCL Cases Reveals Marked Intertumoral and Intratumoral Heterogeneity von Nissen, Michael D., Kusakabe, Manabu, Wang, Xuehai, Simkin, Guillermo, Gracias, Deanne, Tyshchenko, Kateryna, Hill, Ainsleigh, Meskas, Justin, Hung, Stacy, Chavez, Elizabeth A., Ennishi, Daisuke, Aoki, Tomohiro, Sarkozy, Clementine, Connors, Joseph M., Farinha, Pedro, Slack, Graham W., Gascoyne, Randy D., Brinkman, Ryan R., Scott, David W., Steidl, Christian, Weng, Andrew P.

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Mastermind critically regulates Notch-mediated lymphoid cell fate decisions von Maillard, Ivan, Weng, Andrew P., Carpenter, Andrea C., Rodriguez, Carlos G., Sai, Hong, Xu, Lanwei, Allman, David, Aster, Jon C., Pear, Warren S.

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Cell fate decisions in malignant hematopoiesis: leukemia phenotype is determined by distinct functional domains of the MN1 oncogene von Lai, Courteney K, Moon, Yeonsook, Kuchenbauer, Florian, Starzcynowski, Daniel T, Argiropoulos, Bob, Yung, Eric, Beer, Philip, Schwarzer, Adrian, Sharma, Amit, Park, Gyeongsin, Leung, Malina, Lin, Grace, Vollett, Sarah, Fung, Stephen, Eaves, Connie J, Karsan, Aly, Weng, Andrew P, Humphries, R Keith, Heuser, Michael

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Growth Suppression of Pre-T Acute Lymphoblastic Leukemia Cells by Inhibition of Notch Signaling von Weng, Andrew P., Nam, Yunsun, Wolfe, Michael S., Pear, Warren S., Griffin, James D., Blacklow, Stephen C., Aster, Jon C.

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RUNX1 colludes with NOTCH1 to reprogram chromatin in T cell acute lymphoblastic leukemia von Islam, Rashedul, Jenkins, Catherine E., Cao, Qi, Wong, Jasper, Bilenky, Misha, Carles, Annaïck, Moksa, Michelle, Weng, Andrew P., Hirst, Martin

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Notch Subunit Heterodimerization and Prevention of Ligand-Independent Proteolytic Activation Depend, Respectively, on a Novel Domain and the LNR Repeats von Sanchez-Irizarry, Cheryll, Carpenter, Andrea C., Weng, Andrew P., Pear, Warren S., Aster, Jon C., Blacklow, Stephen C.

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Per-channel basis normalization methods for flow cytometry data von Hahne, Florian, Khodabakhshi, Alireza Hadj, Bashashati, Ali, Wong, Chao-Jen, Gascoyne, Randy D, Weng, Andrew P, Seyfert-Margolis, Vicky, Bourcier, Katarzyna, Asare, Adam, Lumley, Thomas, Gentleman, Robert, Brinkman, Ryan R

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Borrelidin, a small molecule nitrile-containing macrolide inhibitor of threonyl-tRNA synthetase, is a potent inducer of apoptosis in acute lymphoblastic leukemia von Habibi, Darya, Ogloff, Nadya, Jalili, Reza B., Yost, Arla, Weng, Andrew P., Ghahary, Aziz, Ong, Christopher J.

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Targeting transcription regulation in cancer with a covalent CDK7 inhibitor von Kwiatkowski, Nicholas, Zhang, Tinghu, Rahl, Peter B., Abraham, Brian J., Reddy, Jessica, Ficarro, Scott B., Dastur, Anahita, Amzallag, Arnaud, Ramaswamy, Sridhar, Tesar, Bethany, Jenkins, Catherine E., Hannett, Nancy M., McMillin, Douglas, Sanda, Takaomi, Sim, Taebo, Kim, Nam Doo, Look, Thomas, Mitsiades, Constantine S., Weng, Andrew P., Brown, Jennifer R., Benes, Cyril H., Marto, Jarrod A., Young, Richard A., Gray, Nathanael S.

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