Intercellular nanovesicle‐mediated microRNA transfer: A mechanism of environmental modulation of hepatocellular cancer cell growth von Kogure, Takayuki, Lin, Wen‐Lang, Yan, Irene K., Braconi, Chiara, Patel, Tushar

Volltext

Tangential Flow Filtration for Highly Efficient Concentration of Extracellular Vesicles from Large Volumes of Fluid von Busatto, Sara, Vilanilam, George, Ticer, Taylor, Lin, Wen-Lang, Dickson, Dennis W, Shapiro, Shane, Bergese, Paolo, Wolfram, Joy

Volltext

The ALS disease-associated mutant TDP-43 impairs mitochondrial dynamics and function in motor neurons von Wang, Wenzhang, Li, Li, Lin, Wen-Lang, Dickson, Dennis W, Petrucelli, Leonard, Zhang, Teng, Wang, Xinglong

Volltext

ER–mitochondria associations are regulated by the VAPB–PTPIP51 interaction and are disrupted by ALS/FTD-associated TDP-43 von Stoica, Radu, De Vos, Kurt J., Paillusson, Sébastien, Mueller, Sarah, Sancho, Rosa M., Lau, Kwok-Fai, Vizcay-Barrena, Gema, Lin, Wen-Lang, Xu, Ya-Fei, Lewis, Jada, Dickson, Dennis W., Petrucelli, Leonard, Mitchell, Jacqueline C., Shaw, Christopher E., Miller, Christopher C. J.

Volltext

Heterochromatin anomalies and double-stranded RNA accumulation underlie C9orf72 poly(PR) toxicity von Zhang, Yong-Jie, Guo, Lin, Gonzales, Patrick K, Gendron, Tania F, Wu, Yanwei, Jansen-West, Karen, O'Raw, Aliesha D, Pickles, Sarah R, Prudencio, Mercedes, Carlomagno, Yari, Gachechiladze, Mariam A, Ludwig, Connor, Tian, Ruilin, Chew, Jeannie, DeTure, Michael, Lin, Wen-Lang, Tong, Jimei, Daughrity, Lillian M, Yue, Mei, Song, Yuping, Andersen, Jonathan W, Castanedes-Casey, Monica, Kurti, Aishe, Datta, Abhishek, Antognetti, Giovanna, McCampbell, Alexander, Rademakers, Rosa, Oskarsson, Björn, Dickson, Dennis W, Kampmann, Martin, Ward, Michael E, Fryer, John D, Link, Christopher D, Shorter, James, Petrucelli, Leonard

Volltext

Unconventional Translation of C9ORF72 GGGGCC Expansion Generates Insoluble Polypeptides Specific to c9FTD/ALS von Ash, Peter E.A., Bieniek, Kevin F., Gendron, Tania F., Caulfield, Thomas, Lin, Wen-Lang, DeJesus-Hernandez, Mariely, van Blitterswijk, Marka M., Jansen-West, Karen, Paul, Joseph W., Rademakers, Rosa, Boylan, Kevin B., Dickson, Dennis W., Petrucelli, Leonard

Volltext

TDP-43 immunoreactivity in hippocampal sclerosis and Alzheimer's disease von Amador-Ortiz, Catalina, Lin, Wen-Lang, Ahmed, Zeshan, Personett, David, Davies, Peter, Duara, Ranjan, Graff-Radford, Neill R., Hutton, Michael L., Dickson, Dennis W.

Volltext

Aggregation-prone c9FTD/ALS poly(GA) RAN-translated proteins cause neurotoxicity by inducing ER stress von Zhang, Yong-Jie, Jansen-West, Karen, Xu, Ya-Fei, Gendron, Tania F., Bieniek, Kevin F., Lin, Wen-Lang, Sasaguri, Hiroki, Caulfield, Thomas, Hubbard, Jaime, Daughrity, Lillian, Chew, Jeannie, Belzil, Veronique V., Prudencio, Mercedes, Stankowski, Jeannette N., Castanedes-Casey, Monica, Whitelaw, Ena, Ash, Peter E. A., DeTure, Michael, Rademakers, Rosa, Boylan, Kevin B., Dickson, Dennis W., Petrucelli, Leonard

Volltext

Strikingly Different Clinicopathological Phenotypes Determined by Progranulin-Mutation Dosage von Smith, Katherine R., Damiano, John, Franceschetti, Silvana, Carpenter, Stirling, Canafoglia, Laura, Morbin, Michela, Rossi, Giacomina, Pareyson, Davide, Mole, Sara E., Staropoli, John F., Sims, Katherine B., Lewis, Jada, Lin, Wen-Lang, Dickson, Dennis W., Dahl, Hans-Henrik, Bahlo, Melanie, Berkovic, Samuel F.

Volltext

Wild-type human TDP-43 expression causes TDP-43 phosphorylation, mitochondrial aggregation, motor deficits, and early mortality in transgenic mice von Xu, Ya-Fei, Gendron, Tania F, Zhang, Yong-Jie, Lin, Wen-Lang, D'Alton, Simon, Sheng, Hong, Casey, Monica Castanedes, Tong, Jimei, Knight, Joshua, Yu, Xin, Rademakers, Rosa, Boylan, Kevin, Hutton, Mike, McGowan, Eileen, Dickson, Dennis W, Lewis, Jada, Petrucelli, Leonard

Volltext

Aberrant cleavage of TDP-43 enhances aggregation and cellular toxicity von Zhang, Yong-Jie, Xu, Ya-Fei, Cook, Casey, Gendron, Tania F, Roettges, Paul, Link, Christopher D, Lin, Wen-Lang, Tong, Jimei, Castanedes-Casey, Monica, Ash, Peter, Gass, Jennifer, Rangachari, Vijayaraghavan, Buratti, Emanuele, Baralle, Francisco, Golde, Todd E, Dickson, Dennis W, Petrucelli, Leonard

Volltext

Autophagic-lysosomal perturbation enhances tau aggregation in transfectants with induced wild-type tau expression von Hamano, Tadanori, Gendron, Tania F., Causevic, Ena, Yen, Shu-Hui, Lin, Wen-Lang, Isidoro, Ciro, DeTure, Michael, Ko, Li-wen

Volltext

Perry Syndrome: A Distinctive Type of TDP-43 Proteinopathy von Mishima, Takayasu, Koga, Shunsuke, Lin, Wen-Lang, Kasanuki, Koji, Castanedes-Casey, Monica, Wszolek, Zbigniew K, Oh, Shin J, Tsuboi, Yoshio, Dickson, Dennis W

Volltext

Accelerated Lipofuscinosis and Ubiquitination in Granulin Knockout Mice Suggest a Role for Progranulin in Successful Aging von Ahmed, Zeshan, Sheng, Hong, Xu, Ya-fei, Lin, Wen-Lang, Innes, Amy E, Gass, Jennifer, Yu, Xin, Hou, Harold, Chiba, Shuichi, Yamanouchi, Keitaro, Leissring, Malcolm, Petrucelli, Leonard, Nishihara, Masugi, Hutton, Michael L, McGowan, Eileen, Dickson, Dennis W, Lewis, Jada

Volltext

Ultrastructural localization of TDP-43 in filamentous neuronal inclusions in various neurodegenerative diseases von Lin, Wen-Lang, Dickson, Dennis W.

Volltext

Casein kinase II induced polymerization of soluble TDP-43 into filaments is inhibited by heat shock proteins von Carlomagno, Yari, Zhang, Yongjie, Davis, Mary, Lin, Wen-Lang, Cook, Casey, Dunmore, Judy, Tay, William, Menkosky, Kyle, Cao, Xiangkun, Petrucelli, Leonard, Deture, Michael

Volltext

Mitophagy alterations in Alzheimer's disease are associated with granulovacuolar degeneration and early tau pathology von Hou, Xu, Watzlawik, Jens O., Cook, Casey, Liu, Chia‐Chen, Kang, Silvia S., Lin, Wen‐Lang, DeTure, Michael, Heckman, Michael G., Diehl, Nancy N., Al‐Shaikh, Fadi S. Hanna, Walton, Ronald L., Ross, Owen A., Melrose, Heather L., Ertekin‐Taner, Nilüfer, Bu, Guojun, Petrucelli, Leonard, Fryer, John D., Murray, Melissa E., Dickson, Dennis W., Fiesel, Fabienne C., Springer, Wolfdieter

Volltext

Expression of mutant TDP-43 induces neuronal dysfunction in transgenic mice von Xu, Ya-Fei, Zhang, Yong-Jie, Lin, Wen-Lang, Cao, Xiangkun, Stetler, Caroline, Dickson, Dennis W, Lewis, Jada, Petrucelli, Leonard

Volltext

p62 Pathology Model in the Rat Substantia Nigra with Filamentous Inclusions and Progressive Neurodegeneration von Jackson, Kasey L, Lin, Wen-Lang, Miriyala, Sumitra, Dayton, Robert D, Panchatcharam, Manikandan, McCarthy, Kevin J, Castanedes-Casey, Monica, Dickson, Dennis W, Klein, Ronald L

Volltext

Aβ42 Is Essential for Parenchymal and Vascular Amyloid Deposition in Mice von McGowan, Eileen, Pickford, Fiona, Kim, Jungsu, Onstead, Luisa, Eriksen, Jason, Yu, Cindy, Skipper, Lisa, Murphy, M. Paul, Beard, Jenny, Das, Pritam, Jansen, Karen, DeLucia, Michael, Lin, Wen-Lang, Dolios, Georgia, Wang, Rong, Eckman, Christopher B., Dickson, Dennis W., Hutton, Mike, Hardy, John, Golde, Todd

Volltext