The lingering mysteries of metastatic recurrence in breast cancer von Riggio, Alessandra I., Varley, Katherine E., Welm, Alana L.

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Understanding the Bone in Cancer Metastasis von Fornetti, Jaime, Welm, Alana L, Stewart, Sheila A

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Protective autophagy elicited by RAF→MEK→ERK inhibition suggests a treatment strategy for RAS-driven cancers von Kinsey, Conan G., Camolotto, Soledad A., Boespflug, Amelie M., Guillen, Katrin P., Foth, Mona, Truong, Amanda, Schuman, Sophia S., Shea, Jill E., Seipp, Michael T., Yap, Jeffrey T., Burrell, Lance D., Lum, David H., Whisenant, Jonathan R., Gilcrease, G. Weldon, Cavalieri, Courtney C., Rehbein, Kaitrin M., Cutler, Stephanie L., Affolter, Kajsa E., Welm, Alana L., Welm, Bryan E., Scaife, Courtney L., Snyder, Eric L., McMahon, Martin

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Plasma exosome microRNAs are indicative of breast cancer von Hannafon, Bethany N, Trigoso, Yvonne D, Calloway, Cameron L, Zhao, Y Daniel, Lum, David H, Welm, Alana L, Zhao, Zhizhuang J, Blick, Kenneth E, Dooley, William C, Ding, W Q

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A Biobank of Breast Cancer Explants with Preserved Intra-tumor Heterogeneity to Screen Anticancer Compounds von Bruna, Alejandra, Rueda, Oscar M., Greenwood, Wendy, Batra, Ankita Sati, Callari, Maurizio, Batra, Rajbir Nath, Pogrebniak, Katherine, Sandoval, Jose, Cassidy, John W., Tufegdzic-Vidakovic, Ana, Sammut, Stephen-John, Jones, Linda, Provenzano, Elena, Baird, Richard, Eirew, Peter, Hadfield, James, Eldridge, Matthew, McLaren-Douglas, Anne, Barthorpe, Andrew, Lightfoot, Howard, O’Connor, Mark J., Gray, Joe, Cortes, Javier, Baselga, Jose, Marangoni, Elisabetta, Welm, Alana L., Aparicio, Samuel, Serra, Violeta, Garnett, Mathew J., Caldas, Carlos

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Cancer Cells Co-opt the Neuronal Redox-Sensing Channel TRPA1 to Promote Oxidative-Stress Tolerance von Takahashi, Nobuaki, Chen, Hsing-Yu, Harris, Isaac S., Stover, Daniel G., Selfors, Laura M., Bronson, Roderick T., Deraedt, Thomas, Cichowski, Karen, Welm, Alana L., Mori, Yasuo, Mills, Gordon B., Brugge, Joan S.

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Tumoural activation of TLR3–SLIT2 axis in endothelium drives metastasis von Tavora, Bernardo, Mederer, Tobias, Wessel, Kai J., Ruffing, Simon, Sadjadi, Mahan, Missmahl, Marc, Ostendorf, Benjamin N., Liu, Xuhang, Kim, Ji-Young, Olsen, Olav, Welm, Alana L., Goodarzi, Hani, Tavazoie, Sohail F.

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Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts von Woo, Xing Yi, Giordano, Jessica, Srivastava, Anuj, Zhao, Zi-Ming, Lloyd, Michael W., de Bruijn, Roebi, Suh, Yun-Suhk, Patidar, Rajesh, Chen, Li, Scherer, Sandra, Bailey, Matthew H., Yang, Chieh-Hsiang, Cortes-Sanchez, Emilio, Xi, Yuanxin, Wang, Jing, Wickramasinghe, Jayamanna, Kossenkov, Andrew V., Rebecca, Vito W., Sun, Hua, Mashl, R. Jay, Davies, Sherri R., Jeon, Ryan, Frech, Christian, Randjelovic, Jelena, Rosains, Jacqueline, Galimi, Francesco, Bertotti, Andrea, Lafferty, Adam, O’Farrell, Alice C., Modave, Elodie, Lambrechts, Diether, ter Brugge, Petra, Serra, Violeta, Marangoni, Elisabetta, El Botty, Rania, Kim, Hyunsoo, Kim, Jong-Il, Yang, Han-Kwang, Lee, Charles, Dean, Dennis A., Davis-Dusenbery, Brandi, Evrard, Yvonne A., Doroshow, James H., Welm, Alana L., Welm, Bryan E., Lewis, Michael T., Fang, Bingliang, Roth, Jack A., Meric-Bernstam, Funda, Herlyn, Meenhard, Davies, Michael A., Ding, Li, Li, Shunqiang, Govindan, Ramaswamy, Isella, Claudio, Moscow, Jeffrey A., Trusolino, Livio, Byrne, Annette T., Jonkers, Jos, Bult, Carol J., Medico, Enzo, Chuang, Jeffrey H.

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Metabolic reprogramming in triple-negative breast cancer through Myc suppression of TXNIP von Shen, Liangliang, O’Shea, John M., Kaadige, Mohan R., Cunha, Stéphanie, Wilde, Blake R., Cohen, Adam L., Welm, Alana L., Ayer, Donald E.

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Comprehensive characterization of 536 patient-derived xenograft models prioritizes candidatesfor targeted treatment von Sun, Hua, Cao, Song, Mashl, R. Jay, Mo, Chia-Kuei, Zaccaria, Simone, Wendl, Michael C., Davies, Sherri R., Bailey, Matthew H., Primeau, Tina M., Hoog, Jeremy, Mudd, Jacqueline L., Dean, Dennis A., Patidar, Rajesh, Chen, Li, Wyczalkowski, Matthew A., Jayasinghe, Reyka G., Rodrigues, Fernanda Martins, Terekhanova, Nadezhda, Li, Yize, Lim, Kian-Huat, Wang-Gillam, Andrea, Van Tine, Brian A., Ma, Cynthia X., Aft, Rebecca, Fuh, Katherine C., Schwarz, Julie K., Zevallos, Jose P., Puram, Sidharth, Dipersio, John F., Consortium, Nci PDXNet, Davis-Dusenbery, Brandi, Ellis, Matthew J., Lewis, Michael T., Davies, Michael A., Herlyn, Meenhard, Fang, Bingliang, Roth, Jack A., Welm, Alana L., Welm, Bryan E., Meric-Bernstam, Funda, Chen, Feng, Fields, Ryan C., Li, Shunqiang, Govindan, Ramaswamy, Doroshow, James H., Moscow, Jeffrey A., Evrard, Yvonne A., Chuang, Jeffrey H., Raphael, Benjamin J., Ding, Li

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Functional precision oncology: Testing tumors with drugs to identify vulnerabilities and novel combinations von Letai, Anthony, Bhola, Patrick, Welm, Alana L.

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A human breast cancer-derived xenograft and organoid platform for drug discovery and precision oncology von Guillen, Katrin P, Fujita, Maihi, Butterfield, Andrew J, Scherer, Sandra D, Bailey, Matthew H, Chu, Zhengtao, DeRose, Yoko S, Zhao, Ling, Cortes-Sanchez, Emilio, Yang, Chieh-Hsiang, Toner, Jennifer, Wang, Guoying, Qiao, Yi, Huang, Xiaomeng, Greenland, Jeffery A, Vahrenkamp, Jeffery M, Lum, David H, Factor, Rachel E, Nelson, Edward W, Matsen, Cindy B, Poretta, Jane M, Rosenthal, Regina, Beck, Anna C, Buys, Saundra S, Vaklavas, Christos, Ward, John H, Jensen, Randy L, Jones, Kevin B, Li, Zheqi, Oesterreich, Steffi, Dobrolecki, Lacey E, Pathi, Satya S, Woo, Xing Yi, Berrett, Kristofer C, Wadsworth, Mark E, Chuang, Jeffrey H, Lewis, Michael T, Marth, Gabor T, Gertz, Jason, Varley, Katherine E, Welm, Bryan E, Welm, Alana L

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Dll1+ quiescent tumor stem cells drive chemoresistance in breast cancer through NF-κB survival pathway von Kumar, Sushil, Nandi, Ajeya, Singh, Snahlata, Regulapati, Rohan, Li, Ning, Tobias, John W., Siebel, Christian W., Blanco, Mario Andres, Klein-Szanto, Andres J., Lengner, Christopher, Welm, Alana L., Kang, Yibin, Chakrabarti, Rumela

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Transient Low Doses of DNA-Demethylating Agents Exert Durable Antitumor Effects on Hematological and Epithelial Tumor Cells von Tsai, Hsing-Chen, Li, Huili, Van Neste, Leander, Cai, Yi, Robert, Carine, Rassool, Feyruz V., Shin, James J., Harbom, Kirsten M., Beaty, Robert, Pappou, Emmanouil, Harris, James, Yen, Ray-Whay Chiu, Ahuja, Nita, Brock, Malcolm V., Stearns, Vered, Feller-Kopman, David, Yarmus, Lonny B., Lin, Yi-Chun, Welm, Alana L., Issa, Jean-Pierre, Minn, Il, Matsui, William, Jang, Yoon-Young, Sharkis, Saul J., Baylin, Stephen B., Zahnow, Cynthia A.

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CD229 CAR T cells eliminate multiple myeloma and tumor propagating cells without fratricide von Radhakrishnan, Sabarinath V., Luetkens, Tim, Scherer, Sandra D., Davis, Patricia, Vander Mause, Erica R., Olson, Michael L., Yousef, Sara, Panse, Jens, Abdiche, Yasmina, Li, K. David, Miles, Rodney R., Matsui, William, Welm, Alana L., Atanackovic, Djordje

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Preclinical Evaluation of Fatty Acid Synthase and EGFR Inhibition in Triple-Negative Breast Cancer von Giró-Perafita, Ariadna, Palomeras, Sònia, Lum, David H, Blancafort, Adriana, Viñas, Gemma, Oliveras, Glòria, Pérez-Bueno, Ferran, Sarrats, Ariadna, Welm, Alana L, Puig, Teresa

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An immune-humanized patient-derived xenograft model of estrogen-independent, hormone receptor positive metastatic breast cancer von Scherer, Sandra D., Riggio, Alessandra, Haroun, Fadi, DeRose, Yoko S., Ekiz, H. Atakan, Fujita, Maihi, Toner, Jennifer, Zhao, Ling, Li, Zheqi, Oesterreich, Steffi, Samatar, Ahmed A., Welm, Alana L.

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Invasive Lobular Carcinoma Cell Lines Are Characterized by Unique Estrogen-Mediated Gene Expression Patterns and Altered Tamoxifen Response von SIKORA, Matthew J, COOPER, Kristine L, BAHREINI, Amir, LUTHRA, Soumya, GUOYING WANG, CHANDRAN, Uma R, DAVIDSON, Nancy E, DABBS, David J, WELM, Alana L, OESTERREICH, Steffi

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Epigenetic silencing of TGFBI confers resistance to trastuzumab in human breast cancer von Palomeras, Sònia, Diaz-Lagares, Ángel, Viñas, Gemma, Setien, Fernando, Ferreira, Humberto J, Oliveras, Glòria, Crujeiras, Ana B, Hernández, Alejandro, Lum, David H, Welm, Alana L, Esteller, Manel, Puig, Teresa

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Transferred mitochondria accumulate reactive oxygen species, promoting proliferation von Kidwell, Chelsea U, Casalini, Joseph R, Pradeep, Soorya, Scherer, Sandra D, Greiner, Daniel, Bayik, Defne, Watson, Dionysios C, Olson, Gregory S, Lathia, Justin D, Johnson, Jarrod S, Rutter, Jared, Welm, Alana L, Zangle, Thomas A, Roh-Johnson, Minna

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