The TGF-β Signaling Regulator PMEPA1 Suppresses Prostate Cancer Metastases to Bone von Fournier, Pierrick G.J., Juárez, Patricia, Jiang, Guanglong, Clines, Gregory A., Niewolna, Maria, Kim, Hun Soo, Walton, Holly W., Peng, Xiang Hong, Liu, Yunlong, Mohammad, Khalid S., Wells, Clark D., Chirgwin, John M., Guise, Theresa A.

Volltext

Serum deprivation inhibits the transcriptional co-activator YAP and cell growth via phosphorylation of the 130-kDa isoform of Angiomotin by the LATS1/2 protein kinases von Adler, Jacob J., Johnson, Derrick E., Heller, Brigitte L., Bringman, Lauren R., Ranahan, William P., Conwell, Michael D., Sun, Yang, Hudmon, Andy, Wells, Clark D.

Volltext

Primary cilia signaling mediates intraocular pressure sensation von Luo, Na, Conwell, Michael D., Chen, Xingjuan, Kettenhofen, Christine Insinna, Westlake, Christopher J., Cantor, Louis B., Wells, Clark D., Weinreb, Robert N., Corson, Timothy W., Spandau, Dan F., Joos, Karen M., Iomini, Carlo, Obukhov, Alexander G., Sun, Yang

Volltext

Therapeutic Potential of Targeting the Oncogenic SHP2 Phosphatase von Zeng, Li-Fan, Zhang, Ruo-Yu, Yu, Zhi-Hong, Li, Sijiu, Wu, Li, Gunawan, Andrea M, Lane, Brandon S, Mali, Raghuveer S, Li, Xingjun, Chan, Rebecca J, Kapur, Reuben, Wells, Clark D, Zhang, Zhong-Yin

Volltext

The RGS-RhoGEFs control the amplitude of YAP1 activation by serum von Lane, Brandon S., Heller, Brigitte, Hollenberg, Morley D., Wells, Clark D.

Volltext

A Rich1/Amot Complex Regulates the Cdc42 GTPase and Apical-Polarity Proteins in Epithelial Cells von Wells, Clark D., Fawcett, James P., Traweger, Andreas, Yamanaka, Yojiro, Goudreault, Marilyn, Elder, Kelly, Kulkarni, Sarang, Gish, Gerald, Virag, Cristina, Lim, Caesar, Colwill, Karen, Starostine, Andrei, Metalnikov, Pavel, Pawson, Tony

Volltext

OCRL localizes to the primary cilium: a new role for cilia in Lowe syndrome von NA LUO, WEST, Callah C, MURGA-ZAMALLOA, Carlos A, SUN, Lou, ANDERSON, Ryan M, WELLS, Clark D, WEINREB, Robert N, TRAVERS, Jeffrey B, KHANNA, Hemant, YANG SUN

Volltext

Starch Binding Domain-containing Protein 1/Genethonin 1 Is a Novel Participant in Glycogen Metabolism von Jiang, Sixin, Heller, Brigitte, Tagliabracci, Vincent S., Zhai, Lanmin, Irimia, Jose M., DePaoli-Roach, Anna A., Wells, Clark D., Skurat, Alexander V., Roach, Peter J.

Volltext

Proteomic, Functional, and Domain-Based Analysis of In Vivo 14-3-3 Binding Proteins Involved in Cytoskeletal Regulation and Cellular Organization von Jin, Jing, Smith, F.Donelson, Stark, Chris, Wells, Clark D., Fawcett, James P., Kulkarni, Sarang, Metalnikov, Pavel, O'Donnell, Paul, Taylor, Paul, Taylor, Lorne, Zougman, Alexandre, Woodgett, James R., Langeberg, Lorene K., Scott, John D., Pawson, Tony

Volltext

Modulation of Rho Guanine Exchange Factor Lfc Activity by Protein Kinase A-Mediated Phosphorylation von Meiri, David, Greeve, Melissa A., Brunet, Andrea, Finan, Dina, Wells, Clark D., LaRose, Jose, Rottapel, Robert

Volltext

Starch-binding domain-containing protein 1 (Stbd1) and glycogen metabolism: Identification of the Atg8 family interacting motif (AIM) in Stbd1 required for interaction with GABARAP... von Jiang, Sixin, Wells, Clark D., Roach, Peter J.

Volltext

Small-Molecule Covalent Modification of Conserved Cysteine Leads to Allosteric Inhibition of the TEAD⋅Yap Protein-Protein Interaction von Bum-Erdene, Khuchtumur, Zhou, Donghui, Gonzalez-Gutierrez, Giovanni, Ghozayel, Mona K., Si, Yubing, Xu, David, Shannon, Harlan E., Bailey, Barbara J., Corson, Timothy W., Pollok, Karen E., Wells, Clark D., Meroueh, Samy O.

Volltext

Identification of Specific Lysines and Arginines That Mediate Angiomotin Membrane Association von Hall, Le’Celia, Donovan, Emily, Araya, Michael, Idowa, Eniola, Jiminez-Segovia, Ilse, Folck, Anthony, Wells, Clark D, Kimble-Hill, Ann C

Volltext

The Rho GTP Exchange Factor Lfc Promotes Spindle Assembly in Early Mitosis von Bakal, Christopher J., Finan, Dina, LaRose, José, Wells, Clark D., Gish, Gerald, Kulkarni, Sarang, DeSepulveda, Paulo, Wilde, Andrew, Rottapel, Robert, Pawson, Anthony J.

Volltext

Mechanisms for Reversible Regulation between G13 and Rho Exchange Factors von Wells, Clark D, Liu, Mu-Ya, Jackson, Mandy, Gutowski, Stephen, Sternweis, Pamela M, Rothstein, Jeffrey D, Kozasa, Tohru, Sternweis, Paul C

Volltext

Amot130 Adapts Atrophin-1 Interacting Protein 4 to Inhibit Yes-associated Protein Signaling and Cell Growth von Adler, Jacob J., Heller, Brigitte L., Bringman, Lauren R., Ranahan, William P., Cocklin, Ross R., Goebl, Mark G., Oh, Misook, Lim, Hyun-Suk, Ingham, Robert J., Wells, Clark D.

Volltext

Combination therapy in a xenograft model of glioblastoma: enhancement of the antitumor activity of temozolomide by an MDM2 antagonist von Wang, Haiyan, Cai, Shanbao, Bailey, Barbara J, Reza Saadatzadeh, M, Ding, Jixin, Tonsing-Carter, Eva, Georgiadis, Taxiarchis M, Zachary Gunter, T, Long, Eric C, Minto, Robert E, Gordon, Kevin R, Sen, Stephanie E, Cai, Wenjing, Eitel, Jacob A, Waning, David L, Bringman, Lauren R, Wells, Clark D, Murray, Mary E, Sarkaria, Jann N, Gelbert, Lawrence M, Jones, David R, Cohen-Gadol, Aaron A, Mayo, Lindsey D, Shannon, Harlan E, Pollok, Karen E

Volltext

Phenotypic Screening of Chemical Libraries Enriched by Molecular Docking to Multiple Targets Selected from Glioblastoma Genomic Data von Xu, David, Zhou, Donghui, Bum-Erdene, Khuchtumur, Bailey, Barbara J., Sishtla, Kamakshi, Liu, Sheng, Wan, Jun, Aryal, Uma K., Lee, Jonathan A., Wells, Clark D., Fishel, Melissa L., Corson, Timothy W., Pollok, Karen E., Meroueh, Samy O.

Volltext

Amot Recognizes a Juxtanuclear Endocytic Recycling Compartment via a Novel Lipid Binding Domain von Heller, Brigitte, Adu-Gyamfi, Emmanuel, Smith-Kinnaman, Whitney, Babbey, Cliff, Vora, Mohsin, Xue, Yi, Bittman, Robert, Stahelin, Robert V., Wells, Clark D.

Volltext

PRL-1 Protein Promotes ERK1/2 and RhoA Protein Activation through a Non-canonical Interaction with the Src Homology 3 Domain of p115 Rho GTPase-activating Protein von Bai, Yunpeng, Luo, Yong, Liu, Sijiu, Zhang, Lujuan, Shen, Kui, Dong, Yuanshu, Walls, Chad D., Quilliam, Lawrence A., Wells, Clark D., Cao, Youjia, Zhang, Zhong-Yin

Volltext