Structure-based prediction of HDAC6 substrates validated by enzymatic assay reveals determinants of promiscuity and detects new potential substrates von Varga, Julia K., Diffley, Kelsey, Welker Leng, Katherine R., Fierke, Carol A., Schueler-Furman, Ora

Volltext

Recent Advances in Epigenetic Biomarkers and Epigenetic Targeting in Prostate Cancer von Kumaraswamy, Anbarasu, Welker Leng, Katherine R., Westbrook, Thomas C., Yates, Joel A., Zhao, Shuang G., Evans, Christopher P., Feng, Felix Y., Morgan, Todd M., Alumkal, Joshi J.

Volltext

Phosphorylation of Histone Deacetylase 8: Structural and Mechanistic Analysis of the Phosphomimetic S39E Mutant von Welker Leng, Katherine R, Castañeda, Carol Ann, Decroos, Christophe, Islam, Barira, Haider, Shozeb M, Christianson, David W, Fierke, Carol A

Volltext

BET Bromodomain Inhibition Blocks an AR-Repressed, E2F1-Activated Treatment-Emergent Neuroendocrine Prostate Cancer Lineage Plasticity Program von Kim, Dae-Hwan, Sun, Duanchen, Storck, William K, Welker Leng, Katherine, Jenkins, Chelsea, Coleman, Daniel J, Sampson, David, Guan, Xiangnan, Kumaraswamy, Anbarasu, Rodansky, Eva S, Urrutia, Joshua A, Schwartzman, Jacob A, Zhang, Chao, Beltran, Himisha, Labrecque, Mark P, Morrissey, Colm, Lucas, Jared M, Coleman, Ilsa M, Nelson, Peter S, Corey, Eva, Handelman, Samuel K, Sexton, Jonathan Z, Aggarwal, Rahul, Abida, Wassim, Feng, Felix Y, Small, Eric J, Spratt, Daniel E, Bankhead, 3rd, Armand, Rao, Arvind, Gesner, Emily M, Attwell, Sarah, Lakhotia, Sanjay, Campeau, Eric, Yates, Joel A, Xia, Zheng, Alumkal, Joshi J

Volltext