Open problems in human trait genetics von Brandes, Nadav, Weissbrod, Omer, Linial, Michal

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Functionally informed fine-mapping and polygenic localization of complex trait heritability von Weissbrod, Omer, Hormozdiari, Farhad, Benner, Christian, Cui, Ran, Ulirsch, Jacob, Gazal, Steven, Schoech, Armin P., van de Geijn, Bryce, Reshef, Yakir, Márquez-Luna, Carla, O’Connor, Luke, Pirinen, Matti, Finucane, Hilary K., Price, Alkes L.

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Quantitative analysis of population-scale family trees with millions of relatives von Kaplanis, Joanna, Gordon, Assaf, Shor, Tal, Weissbrod, Omer, Geiger, Dan, Wahl, Mary, Gershovits, Michael, Markus, Barak, Sheikh, Mona, Gymrek, Melissa, Bhatia, Gaurav, MacArthur, Daniel G, Price, Alkes L, Erlich, Yaniv

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An atlas of robust microbiome associations with phenotypic traits based on large-scale cohorts from two continents von Rothschild, Daphna, Leviatan, Sigal, Hanemann, Ariel, Cohen, Yossi, Weissbrod, Omer, Segal, Eran

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Bread Affects Clinical Parameters and Induces Gut Microbiome-Associated Personal Glycemic Responses von Korem, Tal, Zeevi, David, Zmora, Niv, Weissbrod, Omer, Bar, Noam, Lotan-Pompan, Maya, Avnit-Sagi, Tali, Kosower, Noa, Malka, Gal, Rein, Michal, Suez, Jotham, Goldberg, Ben Z., Weinberger, Adina, Levy, Avraham A., Elinav, Eran, Segal, Eran

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Leveraging fine-mapping and multipopulation training data to improve cross-population polygenic risk scores von Weissbrod, Omer, Kanai, Masahiro, Shi, Huwenbo, Gazal, Steven, Peyrot, Wouter J., Khera, Amit V., Okada, Yukinori, Martin, Alicia R., Finucane, Hilary K., Price, Alkes L.

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Utility of polygenic embryo screening for disease depends on the selection strategy von Lencz, Todd, Backenroth, Daniel, Granot-Hershkovitz, Einat, Green, Adam, Gettler, Kyle, Cho, Judy H, Weissbrod, Omer, Zuk, Or, Carmi, Shai

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Improving the informativeness of Mendelian disease-derived pathogenicity scores for common disease von Kim, Samuel S., Dey, Kushal K., Weissbrod, Omer, Márquez-Luna, Carla, Gazal, Steven, Price, Alkes L.

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Estimating variance components in population scale family trees von Shor, Tal, Kalka, Iris, Geiger, Dan, Erlich, Yaniv, Weissbrod, Omer

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Loss of CD55 in Eculizumab-Responsive Protein-Losing Enteropathy von Kurolap, Alina, Eshach-Adiv, Orly, Hershkovitz, Tova, Paperna, Tamar, Mory, Adi, Oz-Levi, Danit, Zohar, Yaniv, Mandel, Hanna, Chezar, Judith, Azoulay, David, Peleg, Sarit, Half, Elizabeth E, Yahalom, Vered, Finkel, Lilach, Weissbrod, Omer, Geiger, Dan, Tabib, Adi, Shaoul, Ron, Magen, Daniella, Bonstein, Lilach, Mevorach, Dror, Baris, Hagit N

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Detecting heritable phenotypes without a model using fast permutation testing for heritability and set-tests von Schweiger, Regev, Fisher, Eyal, Weissbrod, Omer, Rahmani, Elior, Müller-Nurasyid, Martina, Kunze, Sonja, Gieger, Christian, Waldenberger, Melanie, Rosset, Saharon, Halperin, Eran

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Functional disease architectures reveal unique biological role of transposable elements von Hormozdiari, Farhad, van de Geijn, Bryce, Nasser, Joseph, Weissbrod, Omer, Gazal, Steven, Ju, Chelsea J. -T., Connor, Luke O’, Hujoel, Margaux L. A., Engreitz, Jesse, Hormozdiari, Fereydoun, Price, Alkes L.

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Estimating SNP-Based Heritability and Genetic Correlation in Case-Control Studies Directly and with Summary Statistics von Weissbrod, Omer, Flint, Jonathan, Rosset, Saharon

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Fatal thoracic aortic aneurysm and dissection in a large family with a novel MYLK gene mutation: delineation of the clinical phenotype von Shalata, Adel, Mahroom, Mohammad, Milewicz, Dianna M, Limin, Gong, Kassum, Fadi, Badarna, Khader, Tarabeih, Nader, Assy, Nimmer, Fell, Rona, Cohen, Hector, Nashashibi, Munir, Livoff, Alejandro, Azab, Muhammad, Habib, George, Geiger, Dan, Weissbrod, Omer, Nseir, William

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Paradoxical Hypersusceptibility of Drug-resistant Mycobacterium tuberculosis to β-lactam Antibiotics von Keira A. Cohen, Tal El-Hay, Kelly L. Wyres, Omer Weissbrod, Vanisha Munsamy, Chen Yanover, Ranit Aharonov, Oded Shaham, Thomas C. Conway, Yaara Goldschmidt, William R. Bishai, Alexander S. Pym

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From a genome-wide screen of RNAi molecules against SARS-CoV-2 to a validated broad-spectrum and potent prophylaxis von Yogev, Ohad, Weissbrod, Omer, Battistoni, Giorgia, Bressan, Dario, Naamati, Adi, Falciatori, Ilaria, Berkyurek, Ahmet Can, Rasnic, Roni, Izuagbe, Rhys, Hosmillo, Myra, Ilan, Shaul, Grossman, Iris, McCormick, Lauren, Honeycutt, Christopher Cole, Johnston, Timothy, Gagne, Matthew, Douek, Daniel C, Goodfellow, Ian, Hannon, Gregory James, Erlich, Yaniv

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Multikernel linear mixed models for complex phenotype prediction von Weissbrod, Omer, Geiger, Dan, Rosset, Saharon

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Host genetics and microbiome associations through the lens of genome wide association studies von Weissbrod, Omer, Rothschild, Daphna, Barkan, Elad, Segal, Eran

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Bacterial SNPs in the human gut microbiome associate with host BMI von Zahavi, Liron, Lavon, Amit, Reicher, Lee, Shoer, Saar, Godneva, Anastasia, Leviatan, Sigal, Rein, Michal, Weissbrod, Omer, Weinberger, Adina, Segal, Eran

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GLINT: a user-friendly toolset for the analysis of high-throughput DNA-methylation array data von Rahmani, Elior, Yedidim, Reut, Shenhav, Liat, Schweiger, Regev, Weissbrod, Omer, Zaitlen, Noah, Halperin, Eran

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