A structured weight loss program increases gut microbiota phylogenetic diversity and reduces levels of Collinsella in obese type 2 diabetics: A pilot study von Frost, Fabian, Storck, Lena J, Kacprowski, Tim, Gärtner, Simone, Rühlemann, Malte, Bang, Corinna, Franke, Andre, Völker, Uwe, Aghdassi, Ali A, Steveling, Antje, Mayerle, Julia, Weiss, Frank U, Homuth, Georg, Lerch, Markus M

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Large-scale association analyses identify host factors influencing human gut microbiome composition von Kurilshikov, Alexander, Medina-Gomez, Carolina, Bacigalupe, Rodrigo, Radjabzadeh, Djawad, Wang, Jun, Demirkan, Ayse, Le Roy, Caroline I., Raygoza Garay, Juan Antonio, Finnicum, Casey T., Liu, Xingrong, Zhernakova, Daria V., Bonder, Marc Jan, Hansen, Tue H., Frost, Fabian, Rühlemann, Malte C., Turpin, Williams, Moon, Jee-Young, Kim, Han-Na, Lüll, Kreete, Barkan, Elad, Shah, Shiraz A., Fornage, Myriam, Szopinska-Tokov, Joanna, Wallen, Zachary D., Borisevich, Dmitrii, Agreus, Lars, Andreasson, Anna, Bang, Corinna, Bedrani, Larbi, Bell, Jordana T., Bisgaard, Hans, Boehnke, Michael, Boomsma, Dorret I., Burk, Robert D., Claringbould, Annique, Croitoru, Kenneth, Davies, Gareth E., van Duijn, Cornelia M., Duijts, Liesbeth, Falony, Gwen, Fu, Jingyuan, van der Graaf, Adriaan, Hansen, Torben, Homuth, Georg, Hughes, David A., Ijzerman, Richard G., Jackson, Matthew A., Jaddoe, Vincent W. V., Joossens, Marie, Jørgensen, Torben, Keszthelyi, Daniel, Knight, Rob, Laakso, Markku, Laudes, Matthias, Launer, Lenore J., Lieb, Wolfgang, Lusis, Aldons J., Masclee, Ad A. M., Moll, Henriette A., Mujagic, Zlatan, Qibin, Qi, Rothschild, Daphna, Shin, Hocheol, Sørensen, Søren J., Steves, Claire J., Thorsen, Jonathan, Timpson, Nicholas J., Vieira-Silva, Sara, Völker, Uwe, Völzke, Henry, Võsa, Urmo, Wade, Kaitlin H., Walter, Susanna, Watanabe, Kyoko, Weiss, Stefan, Weiss, Frank U., Weissbrod, Omer, Westra, Harm-Jan, Willemsen, Gonneke, Payami, Haydeh, Jonkers, Daisy M. A. E., Arias Vasquez, Alejandro, de Geus, Eco J. C., Stokholm, Jakob, Segal, Eran, Kim, Hyung-Lae, Kaplan, Robert C., Spector, Tim D., Uitterlinden, Andre G., Rivadeneira, Fernando, Franke, Andre, Lerch, Markus M., Franke, Lude, Sanna, Serena, D’Amato, Mauro, Pedersen, Oluf, Paterson, Andrew D., Kraaij, Robert, Raes, Jeroen, Zhernakova, Alexandra

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Cathepsin B-Mediated Activation of Trypsinogen in Endocytosing Macrophages Increases Severity of Pancreatitis in Mice von Sendler, Matthias, Weiss, Frank-Ulrich, Golchert, Janine, Homuth, Georg, van den Brandt, Cindy, Mahajan, Ujjwal M., Partecke, Lars-Ivo, Döring, Paula, Gukovsky, Ilya, Gukovskaya, Anna S., Wagh, Preshit R., Lerch, Markus M., Mayerle, Julia

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Long-term instability of the intestinal microbiome is associated with metabolic liver disease, low microbiota diversity, diabetes mellitus and impaired exocrine pancreatic function von Frost, Fabian, Kacprowski, Tim, Rühlemann, Malte, Pietzner, Maik, Bang, Corinna, Franke, Andre, Nauck, Matthias, Völker, Uwe, Völzke, Henry, Dörr, Marcus, Baumbach, Jan, Sendler, Matthias, Schulz, Christian, Mayerle, Julia, Weiss, Frank U, Homuth, Georg, Lerch, Markus M

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Next generation sequencing pitfalls in diagnosing trypsinogen (PRSS1) mutations in chronic pancreatitis von Weiss, Frank U, Laemmerhirt, Felix, Lerch, Markus M

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Pancreatic cancer risk in hereditary pancreatitis von Weiss, Frank U

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NMR Metabolomics Reveal Urine Markers of Microbiome Diversity and Identify Benzoate Metabolism as a Mediator between High Microbial Alpha Diversity and Metabolic Health von Hertel, Johannes, Fässler, Daniel, Heinken, Almut, Weiß, Frank U, Rühlemann, Malte, Bang, Corinna, Franke, Andre, Budde, Kathrin, Henning, Ann-Kristin, Petersmann, Astrid, Völker, Uwe, Völzke, Henry, Thiele, Ines, Grabe, Hans-Jörgen, Lerch, Markus M, Nauck, Matthias, Friedrich, Nele, Frost, Fabian

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Recruitment of histone deacetylases HDAC1 and HDAC2 by the transcriptional repressor ZEB1 downregulates E-cadherin expression in pancreatic cancer von Aghdassi, Ali, Sendler, Matthias, Guenther, Annett, Mayerle, Julia, Behn, Claas-Olsen, Heidecke, Claus-Dieter, Friess, Helmut, Büchler, Markus, Evert, Matthias, Lerch, Markus M, Weiss, Frank Ulrich

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Immune Cell and Stromal Signature Associated With Progression-Free Survival of Patients With Resected Pancreatic Ductal Adenocarcinoma von Mahajan, Ujjwal Mukund, Langhoff, Eno, Goni, Elisabetta, Costello, Eithne, Greenhalf, William, Halloran, Christopher, Ormanns, Steffen, Kruger, Stephan, Boeck, Stefan, Ribback, Silvia, Beyer, Georg, Dombroswki, Frank, Weiss, Frank-Ulrich, Neoptolemos, John P., Werner, Jens, D’Haese, Jan G., Bazhin, Alexandr, Peterhansl, Julian, Pichlmeier, Svenja, Büchler, Markus W., Kleeff, Jörg, Ganeh, Paula, Sendler, Matthias, Palmer, Daniel H., Kohlmann, Thomas, Rad, Roland, Regel, Ivonne, Lerch, Markus M., Mayerle, Julia

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Identification and validation of a multivariable prediction model based on blood plasma and serum metabolomics for the distinction of chronic pancreatitis subjects from non-pancrea... von Adam, M Gordian, Beyer, Georg, Christiansen, Nicole, Kamlage, Beate, Pilarsky, Christian, Distler, Marius, Fahlbusch, Tim, Chromik, Ansgar, Klein, Fritz, Bahra, Marcus, Uhl, Waldemar, Grützmann, Robert, Mahajan, Ujjwal M, Weiss, Frank U, Mayerle, Julia, Lerch, Markus M

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In mouse chronic pancreatitis CD25+FOXP3+ regulatory T cells control pancreatic fibrosis by suppression of the type 2 immune response von Glaubitz, Juliane, Wilden, Anika, Golchert, Janine, Homuth, Georg, Völker, Uwe, Bröker, Barbara M., Thiele, Thomas, Lerch, Markus M., Mayerle, Julia, Aghdassi, Ali A., Weiss, Frank U., Sendler, Matthias

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Activated regulatory T-cells promote duodenal bacterial translocation into necrotic areas in severe acute pancreatitis von Glaubitz, Juliane, Wilden, Anika, Frost, Fabian, Ameling, Sabine, Homuth, Georg, Mazloum, Hala, Rühlemann, Malte Christoph, Bang, Corinna, Aghdassi, Ali A, Budde, Christoph, Pickartz, Tilmann, Franke, Andre, Bröker, Barbara M, Voelker, Uwe, Mayerle, Julia, Lerch, Markus M, Weiss, Frank-Ulrich, Sendler, Matthias

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Impaired Exocrine Pancreatic Function Associates With Changes in Intestinal Microbiota Composition and Diversity von Frost, Fabian, Kacprowski, Tim, Rühlemann, Malte, Bülow, Robin, Kühn, Jens-Peter, Franke, Andre, Heinsen, Femke-Anouska, Pietzner, Maik, Nauck, Matthias, Völker, Uwe, Völzke, Henry, Aghdassi, Ali A., Sendler, Matthias, Mayerle, Julia, Weiss, Frank U., Homuth, Georg, Lerch, Markus M.

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Carrying asymptomatic gallstones is not associated with changes in intestinal microbiota composition and diversity but cholecystectomy with significant dysbiosis von Frost, Fabian, Kacprowski, Tim, Rühlemann, Malte, Weiss, Stefan, Bang, Corinna, Franke, Andre, Pietzner, Maik, Aghdassi, Ali A., Sendler, Matthias, Völker, Uwe, Völzke, Henry, Mayerle, Julia, Weiss, Frank U., Homuth, Georg, Lerch, Markus M.

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Tumor-Specific Delivery of 5-Fluorouracil–Incorporated Epidermal Growth Factor Receptor–Targeted Aptamers as an Efficient Treatment in Pancreatic Ductal Adenocarcinoma Models von Mahajan, Ujjwal M., Li, Qi, Alnatsha, Ahmed, Maas, Jessica, Orth, Michael, Maier, Sebastian Hubertus, Peterhansl, Julian, Regel, Ivonne, Sendler, Matthias, Wagh, Preshit R., Mishra, Neha, Xue, Yonggan, Allawadhi, Prince, Beyer, Georg, Kühn, Jens-Peter, Marshall, Thomas, Appel, Bettina, Lämmerhirt, Felix, Belka, Claus, Müller, Sabine, Weiss, Frank-Ulrich, Lauber, Kirsten, Lerch, Markus M., Mayerle, Julia

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Exocrine Pancreatic Function Modulates Plasma Metabolites Through Changes in Gut Microbiota Composition von Pietzner, Maik, Budde, Kathrin, Rühlemann, Malte, Völzke, Henry, Homuth, Georg, Weiss, Frank U, Lerch, Markus M, Frost, Fabian

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Tumour-specific delivery of siRNA-coupled superparamagnetic iron oxide nanoparticles, targeted against PLK1, stops progression of pancreatic cancer von Mahajan, Ujjwal M, Teller, Steffen, Sendler, Matthias, Palankar, Raghavendra, van den Brandt, Cindy, Schwaiger, Theresa, Kühn, Jens-Peter, Ribback, Silvia, Glöckl, Gunnar, Evert, Matthias, Weitschies, Werner, Hosten, Norbert, Dombrowski, Frank, Delcea, Mihaela, Weiss, Frank-Ulrich, Lerch, Markus M, Mayerle, Julia

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Tumour necrosis factor α secretion induces protease activation and acinar cell necrosis in acute experimental pancreatitis in mice von Sendler, Matthias, Dummer, Annegret, Weiss, Frank U, Krüger, Burkhard, Wartmann, Thomas, Scharffetter-Kochanek, Karin, van Rooijen, Nico, Malla, Sudarshan Ravi, Aghdassi, Ali, Halangk, Walter, Lerch, Markus M, Mayerle, Julia

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Tissue tolerable plasma (TTP) induces apoptosis in pancreatic cancer cells in vitro and in vivo von Partecke, Lars Ivo, Evert, Katja, Haugk, Jan, Doering, Friderike, Normann, Lars, Diedrich, Stephan, Weiss, Frank-Ulrich, Evert, Matthias, Huebner, Nils Olaf, Guenther, Cristin, Heidecke, Claus Dieter, Kramer, Axel, Bussiahn, René, Weltmann, Klaus-Dieter, Pati, Onur, Bender, Claudia, von Bernstorff, Wolfram

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Consumerization: IT Innovations from the Consumer Market as a Challenge for Corporate IT von Weiß, Frank, Leimeister, Jan Marco

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