A Chemoproteomic Approach to Query the Degradable Kinome Using a Multi-kinase Degrader von Huang, Hai-Tsang, Dobrovolsky, Dennis, Paulk, Joshiawa, Yang, Guang, Weisberg, Ellen L., Doctor, Zainab M., Buckley, Dennis L., Cho, Joong-Heui, Ko, Eunhwa, Jang, Jaebong, Shi, Kun, Choi, Hwan Geun, Griffin, James D., Li, Ying, Treon, Steven P., Fischer, Eric S., Bradner, James E., Tan, Li, Gray, Nathanael S.

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Inhibition of USP10 induces degradation of oncogenic FLT3 von Weisberg, Ellen L, Schauer, Nathan J, Yang, Jing, Lamberto, Ilaria, Doherty, Laura, Bhatt, Shruti, Nonami, Atsushi, Meng, Chengcheng, Letai, Anthony, Wright, Renee, Tiv, Hong, Gokhale, Prafulla C, Ritorto, Maria Stella, De Cesare, Virginia, Trost, Matthias, Christodoulou, Alexandra, Christie, Amanda, Weinstock, David M, Adamia, Sophia, Stone, Richard, Chauhan, Dharminder, Anderson, Kenneth C, Seo, Hyuk-Soo, Dhe-Paganon, Sirano, Sattler, Martin, Gray, Nathanael S, Griffin, James D, Buhrlage, Sara J

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Pathological glycogenesis through glycogen synthase 1 and suppression of excessive AMP kinase activity in myeloid leukemia cells von Bhanot, H, Reddy, M M, Nonami, A, Weisberg, E L, Bonal, D, Kirschmeier, P T, Salgia, S, Podar, K, Galinsky, I, Chowdary, T K, Neuberg, D, Tonon, G, Stone, R M, Asara, J, Griffin, J D, Sattler, M

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Discovery of a Potent and Selective DDR1 Receptor Tyrosine Kinase Inhibitor von Kim, Hyung-Gu, Tan, Li, Weisberg, Ellen L, Liu, Feiyang, Canning, Peter, Choi, Hwan Geun, Ezell, Scott A, Wu, Hong, Zhao, Zheng, Wang, Jinhua, Mandinova, Anna, Griffin, James D, Bullock, Alex N, Liu, Qingsong, Lee, Sam W, Gray, Nathanael S

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HSP70 and FLT3-ITD: Targeting chaperone system to overcome drug resistance von Yang, Jing, Weisberg, Ellen L.

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Selectively targeting FLT3-ITD mutants over FLT3-wt by a novel inhibitor for acute myeloid leukemia von Wang, Aoli, Hu, Chen, Chen, Cheng, Liang, Xiaofei, Wang, Beilei, Zou, Fengming, Yu, Kailin, Li, Feng, Liu, Qingwang, Qi, Ziping, Wang, Junjie, Wang, Wenliang, Wang, Li, Weisberg, Ellen L, Wang, Wenchao, Li, Lili, Ge, Jian, Xia, Ruixiang, Liu, Jing, Liu, Qingsong

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Discovery of a BTK/MNK dual inhibitor for lymphoma and leukemia von Wu, H, Hu, C, Wang, A, Weisberg, E L, Chen, Y, Yun, C-H, Wang, W, Liu, Y, Liu, X, Tian, B, Wang, J, Zhao, Z, Liang, Y, Li, B, Wang, L, Wang, B, Chen, C, Buhrlage, S J, Qi, Z, Zou, F, Nonami, A, Li, Y, Fernandes, S M, Adamia, S, Stone, R M, Galinsky, I A, Wang, X, Yang, G, Griffin, J D, Brown, J R, Eck, M J, Liu, J, Gray, N S, Liu, Q

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Ibrutinib selectively targets FLT3-ITD in mutant FLT3-positive AML von Wu, H, Hu, C, Wang, A, Weisberg, E L, Wang, W, Chen, C, Zhao, Z, Yu, K, Liu, J, Wu, J, Nonami, A, Wang, L, Wang, B, Stone, R M, Liu, S, Griffin, J D, Liu, J, Liu, Q

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Ibrutinib selectively and irreversibly targets EGFR (L858R, Del19) mutant but is moderately resistant to EGFR (T790M) mutant NSCLC Cells von Wu, Hong, Wang, Aoli, Zhang, Wei, Wang, Beilei, Chen, Cheng, Wang, Wenchao, Hu, Chen, Ye, Zi, Zhao, Zheng, Wang, Li, Li, Xixiang, Yu, Kailin, Liu, Juan, Wu, Jiaxin, Yan, Xiao-E, Zhao, Peng, Wang, Jinhua, Wang, Chu, Weisberg, Ellen L, Gray, Nathanael S, Yun, Cai-Hong, Liu, Jing, Chen, Liang, Liu, Qingsong

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BRD9 regulates normal human hematopoietic stem cell function and lineage differentiation von Garg, Swati, Ni, Wei, Chowdhury, Basudev, Weisberg, Ellen L., Sattler, Martin, Griffin, James D.

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Targeting chaperon protein HSP70 as a novel therapeutic strategy for FLT3-ITD-positive acute myeloid leukemia von Hu, Chen, Zou, Fengming, Wang, Aoli, Miao, Weili, Liang, Qianmao, Weisberg, Ellen L., Wang, Yinsheng, Liu, Jing, Wang, Wenchao, Liu, Qingsong

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Structure-Guided Development of a Potent and Selective Non-covalent Active-Site Inhibitor of USP7 von Lamberto, Ilaria, Liu, Xiaoxi, Seo, Hyuk-Soo, Schauer, Nathan J., Iacob, Roxana E., Hu, Wanyi, Das, Deepika, Mikhailova, Tatiana, Weisberg, Ellen L., Engen, John R., Anderson, Kenneth C., Chauhan, Dharminder, Dhe-Paganon, Sirano, Buhrlage, Sara J.

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Ranolazine Safely Decreases Ventricular and Atrial Fibrillation in Timothy Syndrome (LQT8) von SHAH, DIPAK P., BAEZ‐ESCUDERO, JOSE L., WEISBERG, IAN L., BESHAI, JOHN F., BURKE, MARTIN C.

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Discovery of a highly potent FLT3 kinase inhibitor for FLT3-ITD-positive AML von Wu, H, Wang, A, Qi, Z, Li, X, Chen, C, Yu, K, Zou, F, Hu, C, Wang, W, Zhao, Z, Wu, J, Liu, J, Liu, X, Wang, L, Zhang, S, Stone, R M, Galinsky, I A, Griffin, J D, Weinstock, D, Christodoulou, A, Wang, H, Shen, Y, Zhai, Z, Weisberg, E L, Liu, J, Liu, Q

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Aspiration in patients with acute stroke von Daniels, Stephanie K., Brailey, Kevin, Priestly, Daniel H., Herrington, Lisa R., Weisberg, Leon A., Foundas, Anne L.

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Prospective study of atrial natriuretic peptide for the prevention of radiocontrast-induced nephropathy von Kurnik, BR, Allgren, RL, Genter, FC, Solomon, RJ, Bates, ER, Weisberg, LS

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Error Traps in Developing a Pediatric Enhanced Recovery After Surgery (ERAS) Program von Taylor, Christian M, Weisberg, Emily L, Doyle, Nichole M, Glenski, Todd A

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The implementation of a pectus bar insertion enhanced recovery after surgery pathway: A quality improvement initiative von Glenski, Todd A., Taylor, Christian M., Weisberg, Emily L., Doyle, Nichole M., Melanson, Andrea

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The fallacy of the BUN:creatinine ratio in critically ill patients von RACHOIN, Jean-Sebastien, DAHER, Ralph, MOUSSALLEM, Charles, MILCAREK, Barry, HUNTER, Krystal, SCHORR, Christa, ABBOUD, Mariam, HENRY, Patricia, WEISBERG, Lawrence S

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Selective USP7 inhibition elicits cancer cell killing through a p53-dependent mechanism von Schauer, Nathan J., Liu, Xiaoxi, Magin, Robert S., Doherty, Laura M., Chan, Wai Cheung, Ficarro, Scott B., Hu, Wanyi, Roberts, Rebekka M., Iacob, Roxana E., Stolte, Björn, Giacomelli, Andrew O., Perera, Sumner, McKay, Kyle, Boswell, Sarah A., Weisberg, Ellen L., Ray, Arghya, Chauhan, Dharminder, Dhe-Paganon, Sirano, Anderson, Ken C., Griffin, James D., Li, Jianing, Hahn, William C., Sorger, Peter K., Engen, John R., Stegmaier, Kimberly, Marto, Jarrod A., Buhrlage, Sara J.

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