CJ-13610, an orally active inhibitor of 5-lipoxygenase is efficacious in preclinical models of pain von Cortes-Burgos, Luz A., Zweifel, Ben S., Settle, Steven L., Pufahl, Robert A., Anderson, Gary D., Hardy, Medora M., Weir, Dana E., Hu, George, Happa, Fernando A., Stewart, Zachary, Muthian, Shanmugam, Graneto, Matthew J., Masferrer, Jaime L.

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Euthanasia Method for Mice in Rapid Time-Course Pulmonary Pharmacokinetic Studies von Schoell, Adam R, Heyde, Bruce R, Weir, Dana E, Chiang, Po-Chang, Hu, Yiding, Tung, David K

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COVID-19 surveillance in Southeastern Virginia using wastewater-based epidemiology von Gonzalez, Raul, Curtis, Kyle, Bivins, Aaron, Bibby, Kyle, Weir, Mark H., Yetka, Kathleen, Thompson, Hannah, Keeling, David, Mitchell, Jamie, Gonzalez, Dana

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β-Catenin-Driven Cancers Require a YAP1 Transcriptional Complex for Survival and Tumorigenesis von Rosenbluh, Joseph, Nijhawan, Deepak, Cox, Andrew G., Li, Xingnan, Neal, James T., Schafer, Eric J., Zack, Travis I., Wang, Xiaoxing, Tsherniak, Aviad, Schinzel, Anna C., Shao, Diane D., Schumacher, Steven E., Weir, Barbara A., Vazquez, Francisca, Cowley, Glenn S., Root, David E., Mesirov, Jill P., Beroukhim, Rameen, Kuo, Calvin J., Goessling, Wolfram, Hahn, William C.

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Blood pressure and volume management in dialysis: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference von Flythe, Jennifer E., Chang, Tara I., Gallagher, Martin P., Lindley, Elizabeth, Madero, Magdalena, Sarafidis, Pantelis A., Unruh, Mark L., Wang, Angela Yee-Moon, Weiner, Daniel E., Cheung, Michael, Jadoul, Michel, Winkelmayer, Wolfgang C., Polkinghorne, Kevan R., Adragão, Teresa, Anumudu, Samaya J., Chan, Christopher T., Cheung, Alfred K., Costanzo, Maria Rosa, Dasgupta, Indranil, Davenport, Andrew, Davies, Simon J., Dekker, Marijke J.E., Dember, Laura M., Gallego, Daniel, Gómez, Rafael, Hawley, Carmel M., Hecking, Manfred, Iseki, Kunitoshi, Jha, Vivekanand, Kooman, Jeroen P., Kovesdy, Csaba P., Lacson, Eduardo, Liew, Adrian, Lok, Charmaine E., McIntyre, Christopher W., Mehrotra, Rajnish, Miskulin, Dana C., Movilli, Ezio, Paglialonga, Fabio, Pecoits-Filho, Roberto, Perl, Jeff, Pollock, Carol A., Riella, Miguel C., Rossignol, Patrick, Shroff, Rukshana, Solá, Laura, Søndergaard, Henning, Tang, Sydney C.W., Tong, Allison, Tsukamoto, Yusuke, Watnick, Suzanne, Weir, Matthew R., Wetmore, James B., Wilkie, Caroline, Wilkie, Martin

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Computational correction of copy number effect improves specificity of CRISPR–Cas9 essentiality screens in cancer cells von Meyers, Robin M, Bryan, Jordan G, McFarland, James M, Weir, Barbara A, Sizemore, Ann E, Xu, Han, Dharia, Neekesh V, Montgomery, Phillip G, Cowley, Glenn S, Pantel, Sasha, Goodale, Amy, Lee, Yenarae, Ali, Levi D, Jiang, Guozhi, Lubonja, Rakela, Harrington, William F, Strickland, Matthew, Wu, Ting, Hawes, Derek C, Zhivich, Victor A, Wyatt, Meghan R, Kalani, Zohra, Chang, Jaime J, Okamoto, Michael, Stegmaier, Kimberly, Golub, Todd R, Boehm, Jesse S, Vazquez, Francisca, Root, David E, Hahn, William C, Tsherniak, Aviad

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PAK1 is a breast cancer oncogene that coordinately activates MAPK and MET signaling von Shrestha, Y, Schafer, E J, Boehm, J S, Thomas, S R, He, F, Du, J, Wang, S, Barretina, J, Weir, B A, Zhao, J J, Polyak, K, Golub, T R, Beroukhim, R, Hahn, W C

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Genomic Copy Number Dictates a Gene-Independent Cell Response to CRISPR/Cas9 Targeting von Aguirre, Andrew J, Meyers, Robin M, Weir, Barbara A, Vazquez, Francisca, Zhang, Cheng-Zhong, Ben-David, Uri, Cook, April, Ha, Gavin, Harrington, William F, Doshi, Mihir B, Kost-Alimova, Maria, Gill, Stanley, Xu, Han, Ali, Levi D, Jiang, Guozhi, Pantel, Sasha, Lee, Yenarae, Goodale, Amy, Cherniack, Andrew D, Oh, Coyin, Kryukov, Gregory, Cowley, Glenn S, Garraway, Levi A, Stegmaier, Kimberly, Roberts, Charles W, Golub, Todd R, Meyerson, Matthew, Root, David E, Tsherniak, Aviad, Hahn, William C

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Defining a Cancer Dependency Map von Tsherniak, Aviad, Vazquez, Francisca, Montgomery, Phil G., Weir, Barbara A., Kryukov, Gregory, Cowley, Glenn S., Gill, Stanley, Harrington, William F., Pantel, Sasha, Krill-Burger, John M., Meyers, Robin M., Ali, Levi, Goodale, Amy, Lee, Yenarae, Jiang, Guozhi, Hsiao, Jessica, Gerath, William F.J., Howell, Sara, Merkel, Erin, Ghandi, Mahmoud, Garraway, Levi A., Root, David E., Golub, Todd R., Boehm, Jesse S., Hahn, William C.

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Cancer Vulnerabilities Unveiled by Genomic Loss von Nijhawan, Deepak, Zack, Travis I., Ren, Yin, Strickland, Matthew R., Lamothe, Rebecca, Schumacher, Steven E., Tsherniak, Aviad, Besche, Henrike C., Rosenbluh, Joseph, Shehata, Shyemaa, Cowley, Glenn S., Weir, Barbara A., Goldberg, Alfred L., Mesirov, Jill P., Root, David E., Bhatia, Sangeeta N., Beroukhim, Rameen, Hahn, William C.

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CRISPR-Cas9 screen reveals a MYCN-amplified neuroblastoma dependency on EZH2 von Chen, Liying, Alexe, Gabriela, Dharia, Neekesh V, Ross, Linda, Iniguez, Amanda Balboni, Conway, Amy Saur, Wang, Emily Jue, Veschi, Veronica, Lam, Norris, Qi, Jun, Gustafson, W Clay, Nasholm, Nicole, Vazquez, Francisca, Weir, Barbara A, Cowley, Glenn S, Ali, Levi D, Pantel, Sasha, Jiang, Guozhi, Harrington, William F, Lee, Yenarae, Goodale, Amy, Lubonja, Rakela, Krill-Burger, John M, Meyers, Robin M, Tsherniak, Aviad, Root, David E, Bradner, James E, Golub, Todd R, Roberts, Charles Wm, Hahn, William C, Weiss, William A, Thiele, Carol J, Stegmaier, Kimberly

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The efficacy of an immunoisolating membrane system for islet xenotransplantation in minipigs von Neufeld, Tova, Ludwig, Barbara, Barkai, Uriel, Weir, Gordon C, Colton, Clark K, Evron, Yoav, Balyura, Maria, Yavriyants, Karina, Zimermann, Baruch, Azarov, Dmitri, Maimon, Shiri, Shabtay, Noa, Rozenshtein, Tania, Lorber, Dana, Steffen, Anja, Willenz, Udi, Bloch, Konstantine, Vardi, Pnina, Taube, Ran, de Vos, Paul, Lewis, Eli C, Bornstein, Stefan R, Rotem, Avi

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Identification of shared gene expression programs activated in multiple modes of torpor across vertebrate clades von Weir, Kurt, Vega, Natasha, Busa, Veronica F., Sajdak, Ben, Kallestad, Les, Merriman, Dana, Palczewski, Krzysztof, Carroll, Joseph, Blackshaw, Seth

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Selective Inhibition of the Myeloid Src-Family Kinase Fgr Potently Suppresses AML Cell Growth in Vitro and in Vivo von Weir, Mark C, Shu, Sherry T, Patel, Ravi K, Hellwig, Sabine, Chen, Li, Tan, Li, Gray, Nathanael S, Smithgall, Thomas E

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PRMT1-Mediated Translation Regulation Is a Crucial Vulnerability of Cancer von Hsu, Jessie Hao-Ru, Hubbell-Engler, Benjamin, Adelmant, Guillaume, Huang, Jialiang, Joyce, Cailin E, Vazquez, Francisca, Weir, Barbara A, Montgomery, Philip, Tsherniak, Aviad, Giacomelli, Andrew O, Perry, Jennifer A, Trowbridge, Jennifer, Fujiwara, Yuko, Cowley, Glenn S, Xie, Huafeng, Kim, Woojin, Novina, Carl D, Hahn, William C, Marto, Jarrod A, Orkin, Stuart H

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Systematic interrogation of 3q26 identifies TLOC1 and SKIL as cancer drivers von Hagerstrand, Daniel, Tong, Alexander, Schumacher, Steven E, Ilic, Nina, Shen, Rhine R, Cheung, Hiu Wing, Vazquez, Francisca, Shrestha, Yashaswi, Kim, So Young, Giacomelli, Andrew O, Rosenbluh, Joseph, Schinzel, Anna C, Spardy, Nicole A, Barbie, David A, Mermel, Craig H, Weir, Barbara A, Garraway, Levi A, Tamayo, Pablo, Mesirov, Jill P, Beroukhim, Rameen, Hahn, William C

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Dual inhibition of Fes and Flt3 tyrosine kinases potently inhibits Flt3-ITD+ AML cell growth von Weir, Mark C, Hellwig, Sabine, Tan, Li, Liu, Yao, Gray, Nathanael S, Smithgall, Thomas E

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Characterizing genomic alterations in cancer by complementary functional associations von Kim, Jong Wook, Botvinnik, Olga B, Abudayyeh, Omar, Birger, Chet, Rosenbluh, Joseph, Shrestha, Yashaswi, Abazeed, Mohamed E, Hammerman, Peter S, DiCara, Daniel, Konieczkowski, David J, Johannessen, Cory M, Liberzon, Arthur, Alizad-Rahvar, Amir Reza, Alexe, Gabriela, Aguirre, Andrew, Ghandi, Mahmoud, Greulich, Heidi, Vazquez, Francisca, Weir, Barbara A, Van Allen, Eliezer M, Tsherniak, Aviad, Shao, Diane D, Zack, Travis I, Noble, Michael, Getz, Gad, Beroukhim, Rameen, Garraway, Levi A, Ardakani, Masoud, Romualdi, Chiara, Sales, Gabriele, Barbie, David A, Boehm, Jesse S, Hahn, William C, Mesirov, Jill P, Tamayo, Pablo

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Integrative Analysis of 1q23.3 Copy-Number Gain in Metastatic Urothelial Carcinoma von RIESTER, Markus, WERNER, Lillian, CHOUEIRI, Toni K, SIGNORETTI, Sabina, LLORETA, Josep, MARCHIONNI, Luigi, GALLARDO, Enrique, ROJO, Federico, GARCIA, Denise I, CHEKALUK, Yvonne, KWIATKOWSKI, David J, BOCHNER, Bernard H, BELLMUNT, Joaquim, HAHN, William C, LIGON, Azra H, BARLETTA, Justine A, LODA, Massimo, BERMAN, David M, KANTOFF, Philip W, MICHOR, Franziska, ROSENBERG, Jonathan E, SELVARAJAH, Shamini, GUANCIAL, Elizabeth A, WEIR, Barbara A, STACK, Edward C, PARK, Rachel S, O'BRIEN, Robert, SCHUTZ, Fabio A. B

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Provincial Door-to-Needle Improvement Initiative Results in Improved Patient Outcomes Across an Entire Population von Kamal, Noreen, Jeerakathil, Thomas, Stang, Jillian, Liu, Mingfu, Rogers, Edwin, Smith, Eric E., Demchuk, Andrew M., Siddiqui, Muzaffar, Mann, Balraj, Bestard, Jennifer, Lang, Eddy, Shand, Elaine, Benard, Magali, Collins, Lisa, Martin, Kevin, Hartley, Corinna, Reiber, Marnie, Valaire, Shelley, Mrklas, Kelly J., Hill, Michael D.

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