Minireview: The Melanocortin 2 Receptor Accessory Proteins von Webb, Tom R, Clark, Adrian J. L

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JCAD Gene at the 10p11 Coronary Artery Disease Locus Regulates Hippo Signaling in Endothelial Cells von Jones, Peter D, Kaiser, Michael A, Ghaderi Najafabadi, Maryam, Koplev, Simon, Zhao, Yuqi, Douglas, Gillian, Kyriakou, Theodosios, Andrews, Sarah, Rajmohan, Rathinasabapathy, Watkins, Hugh, Channon, Keith M, Ye, Shu, Yang, Xia, Björkegren, Johan L.M, Samani, Nilesh J, Webb, Tom R

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MRAP and MRAP2 are bidirectional regulators of the melanocortin receptor family von Chan, Li F, Webb, Tom R, Chung, Teng-Teng, Meimaridou, Eirini, Cooray, Sadani N, Guasti, Leonardo, Chapple, J. Paul, Egertová, Michaela, Elphick, Maurice R, Cheetham, Michael E, Metherell, Louise A, Clark, Adrian J.L

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Genetic influence on vascular smooth muscle cell apoptosis von McVey, David G., Andreadi, Catherine, Gong, Peng, Stanczyk, Paulina J., Solomon, Charles U., Turner, Lenka, Yan, Liu, Chen, Runji, Cao, Junjun, Nelson, Christopher P., Thompson, John R., Yu, Haojie, Webb, Tom R., Samani, Nilesh J., Ye, Shu

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Novel LOX Variants in Five Families with Aortic/Arterial Aneurysm and Dissection with Variable Connective Tissue Findings von Van Gucht, Ilse, Krebsova, Alice, Diness, Birgitte Rode, Laga, Steven, Adlam, Dave, Kempers, Marlies, Samani, Nilesh J., Webb, Tom R., Baranowska, Ania A., van den Heuvel, Lotte, Perik, Melanie, Luyckx, Ilse, Peeters, Nils, Votypka, Pavel, Macek, Milan, Meester, Josephina, Van Laer, Lut, Verstraeten, Aline, Loeys, Bart L.

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X-Linked Megalocornea Caused by Mutations in CHRDL1 Identifies an Essential Role for Ventroptin in Anterior Segment Development von Webb, Tom R., Matarin, Mar, Gardner, Jessica C., Kelberman, Dan, Hassan, Hala, Ang, Wei, Michaelides, Michel, Ruddle, Jonathan B., Pennell, Craig E., Yazar, Seyhan, Khor, Chiea C., Aung, Tin, Yogarajah, Mahinda, Robson, Anthony G., Holder, Graham E., Cheetham, Michael E., Traboulsi, Elias I., Moore, Anthony T., Sowden, Jane C., Sisodiya, Sanjay M., Mackey, David A., Tuft, Stephen J., Hardcastle, Alison J.

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Association of CHRDL1 mutations and variants with X-linked megalocornea, Neuhäuser syndrome and central corneal thickness von Davidson, Alice E, Cheong, Sek-Shir, Hysi, Pirro G, Venturini, Cristina, Plagnol, Vincent, Ruddle, Jonathan B, Ali, Hala, Carnt, Nicole, Gardner, Jessica C, Hassan, Hala, Gade, Else, Kearns, Lisa, Jelsig, Anne Marie, Restori, Marie, Webb, Tom R, Laws, David, Cosgrove, Michael, Hertz, Jens M, Russell-Eggitt, Isabelle, Pilz, Daniela T, Hammond, Christopher J, Tuft, Stephen J, Hardcastle, Alison J

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Novel loss of function mutation in NOTCH1 in a family with bicuspid aortic valve, ventricular septal defect, thoracic aortic aneurysm, and aortic valve stenosis von Debiec, Radoslaw, Hamby, Stephen E., Jones, Peter D., Coolman, Sue, Asiani, Manish, Kharodia, Shireen, Skinner, Gregory J., Samani, Nilesh J., Webb, Tom R., Bolger, Aidan

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Distinct Melanocortin 2 Receptor Accessory Protein Domains Are Required for Melanocortin 2 Receptor Interaction and Promotion of Receptor Trafficking von Webb, Tom R, Chan, Li, Cooray, Sadani N, Cheetham, Michael E, Chapple, J. Paul, Clark, Adrian J. L

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Long noncoding RNA NEXN-AS1 mitigates atherosclerosis by regulating the actin-binding protein NEXN von Hu, Yan-Wei, Guo, Feng-Xia, Xu, Yuan-Jun, Li, Pan, Lu, Zhi-Feng, McVey, David G, Zheng, Lei, Wang, Qian, Ye, John H, Kang, Chun-Min, Wu, Shao-Guo, Zhao, Jing-Jing, Ma, Xin, Yang, Zhen, Fang, Fu-Chun, Qiu, Yu-Rong, Xu, Bang-Ming, Xiao, Lei, Wu, Qian, Wu, Li-Mei, Ding, Li, Webb, Tom R, Samani, Nilesh J, Ye, Shu

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Diphthamide modification of eEF2 requires a J-domain protein and is essential for normal development von Webb, Tom R, Cross, Sally H, McKie, Lisa, Edgar, Ruth, Vizor, Lucie, Harrison, Jackie, Peters, Jo, Jackson, Ian J

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High prevalence of posterior polymorphous corneal dystrophy in the Czech Republic; linkage disequilibrium mapping and dating an ancestral mutation von Liskova, Petra, Gwilliam, Rhian, Filipec, Martin, Jirsova, Katerina, Reinstein Merjava, Stanislava, Deloukas, Panos, Webb, Tom R, Bhattacharya, Shomi S, Ebenezer, Neil D, Morris, Alex G, Hardcastle, Alison J

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X-linked cataract and Nance-Horan syndrome are allelic disorders von Coccia, Margherita, Brooks, Simon P., Webb, Tom R., Christodoulou, Katja, Wozniak, Izabella O., Murday, Victoria, Balicki, Martha, Yee, Harris A., Wangensteen, Teresia, Riise, Ruth, Saggar, Anand K., Park, Soo-Mi, Kanuga, Naheed, Francis, Peter J., Maher, Eamonn R., Moore, Anthony T., Russell-Eggitt, Isabelle M., Hardcastle, Alison J.

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Effects of Coronary Artery Disease–Associated Variants on Vascular Smooth Muscle Cells von Solomon, Charles U., McVey, David G., Andreadi, Catherine, Gong, Peng, Turner, Lenka, Stanczyk, Paulina J., Khemiri, Sonja, Chamberlain, Julie C., Yang, Wei, Webb, Tom R., Nelson, Christopher P., Samani, Nilesh J., Ye, Shu

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Influence of a Coronary Artery Disease–Associated Genetic Variant on FURIN Expression and Effect of Furin on Macrophage Behavior von Zhao, Guojun, Yang, Wei, Wu, Jingchun, Chen, Bairu, Yang, Xu, Chen, Junhui, McVey, David G, Andreadi, Catherine, Gong, Peng, Webb, Tom R, Samani, Nilesh J, Ye, Shu

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Contribution of NOTCH1 genetic variants to bicuspid aortic valve and other congenital lesions von Debiec, Radoslaw Marek, Hamby, Stephen E, Jones, Peter D, Safwan, Kassem, Sosin, Michael, Hetherington, Simon Lee, Sprigings, David, Sharman, David, Lee, Kelvin, Salahshouri, Pegah, Wheeldon, Nigel, Chukwuemeka, Andrew, Boutziouka, Vasiliki, Elamin, Mohamed, Coolman, Sue, Asiani, Manish, Kharodia, Shireen, Skinner, Gregory J, Samani, Nilesh J, Webb, Tom R, Bolger, Aidan P

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The FES Gene at the 15q26 Coronary-Artery-Disease Locus Inhibits Atherosclerosis von Karamanavi, Elisavet, McVey, David G., van der Laan, Sander W., Stanczyk, Paulina J., Morris, Gavin E., Wang, Yifan, Yang, Wei, Chan, Kenneth, Poston, Robin N., Luo, Jun, Zhou, Xinmiao, Gong, Peng, Jones, Peter D., Cao, Junjun, Kostogrys, Renata B., Webb, Tom R., Pasterkamp, Gerard, Yu, Haojie, Xiao, Qingzhong, Greer, Peter A., Stringer, Emma J., Samani, Nilesh J., Ye, Shu

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Coronary Artery Disease–Associated LIPA Coding Variant rs1051338 Reduces Lysosomal Acid Lipase Levels and Activity in Lysosomes von Morris, Gavin E, Braund, Peter S, Moore, Jasbir S, Samani, Nilesh J, Codd, Veryan, Webb, Tom R

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HHIPL1, a Gene at the 14q32 Coronary Artery Disease Locus, Positively Regulates Hedgehog Signaling and Promotes Atherosclerosis von Aravani, Dimitra, Morris, Gavin E, Jones, Peter D, Tattersall, Helena K, Karamanavi, Elisavet, Kaiser, Michael A, Kostogrys, Renata B, Ghaderi Najafabadi, Maryam, Andrews, Sarah L, Nath, Mintu, Ye, Shu, Stringer, Emma J, Samani, Nilesh J, Webb, Tom R

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Rare loss-of-function mutations of PTGIR are enriched in fibromuscular dysplasia von Georges, Adrien, Albuisson, Juliette, Berrandou, Takiy, Dupré, Délia, Lorthioir, Aurélien, D’Escamard, Valentina, Di Narzo, Antonio F, Kadian-Dodov, Daniella, Olin, Jeffrey W, Warchol-Celinska, Ewa, Prejbisz, Aleksander, Januszewicz, Andrzej, Bruneval, Patrick, Baranowska, Anna A, Webb, Tom R, Hamby, Stephen E, Samani, Nilesh J, Adlam, David, Fendrikova-Mahlay, Natalia, Hazen, Stanley, Wang, Yu, Yang, Min-Lee, Hunker, Kristina, Combaret, Nicolas, Motreff, Pascal, Chédid, Antoine, Fiquet, Béatrice, Plouin, Pierre-François, Mousseaux, Elie, Azarine, Arshid, Amar, Laurence, Azizi, Michel, Gornik, Heather L, Ganesh, Santhi K, Kovacic, Jason C, Jeunemaitre, Xavier, Bouatia-Naji, Nabila

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