Resistance to BET Bromodomain Inhibitors Is Mediated by Kinome Reprogramming in Ovarian Cancer von Kurimchak, Alison M., Shelton, Claude, Duncan, Kelly E., Johnson, Katherine J., Brown, Jennifer, O’Brien, Shane, Gabbasov, Rashid, Fink, Lauren S., Li, Yuesheng, Lounsbury, Nicole, Abou-Gharbia, Magid, Childers, Wayne E., Connolly, Denise C., Chernoff, Jonathan, Peterson, Jeffrey R., Duncan, James S.

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Discovery of Innovative Therapeutics: Today’s Realities and Tomorrow’s Vision. 2. Pharma’s Challenges and Their Commitment to Innovation von Abou-Gharbia, Magid, Childers, Wayne E

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The Resurrection of Phenotypic Drug Discovery von Childers, Wayne E, Elokely, Khaled M, Abou-Gharbia, Magid

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Effects of novel GLT-1 modulator, MC-100093, on neuroinflammatory and neurotrophic biomarkers in mesocorticolimbic brain regions of male alcohol preferring rats exposed chronically... von Travaglianti, Shelby, Alotaibi, Ahmed, Wong, Woonyen, Abou-Gharbia, Magid, Childers, Wayne, Sari, Youssef

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N-Methyl-d-Aspartate Antagonists and Neuropathic Pain:  The Search for Relief von Childers, Wayne E, Baudy, Reinhardt B

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Targeting Calcium Signaling Induces Epigenetic Reactivation of Tumor Suppressor Genes in Cancer von Raynal, Noël J-M, Lee, Justin T, Wang, Youjun, Beaudry, Annie, Madireddi, Priyanka, Garriga, Judith, Malouf, Gabriel G, Dumont, Sarah, Dettman, Elisha J, Gharibyan, Vazganush, Ahmed, Saira, Chung, Woonbok, Childers, Wayne E, Abou-Gharbia, Magid, Henry, Ryan A, Andrews, Andrew J, Jelinek, Jaroslav, Cui, Ying, Baylin, Stephen B, Gill, Donald L, Issa, Jean-Pierre J

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“I’ll Be Back”: The Resurrection of Dezocine von Childers, Wayne E, Abou-Gharbia, Magid A

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A novel monobactam lacking antimicrobial activity, MC-100093, reduces sex-specific ethanol preference and depressive-like behaviors in mice von León, Brandon Emanuel, Peyton, Lee, Essa, Hesham, Wieden, Tia, Marion, Nicole, Childers, Wayne E., Abou-Gharbia, Magid, Choi, Doo-Sup

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Structure–Activity Relationship of a Pyrrole Based Series of PfPKG Inhibitors as Anti-Malarials von Gilleran, John A., Ashraf, Kutub, Delvillar, Melvin, Eck, Tyler, Fondekar, Raheel, Miller, Edward B., Hutchinson, Ashley, Dong, Aiping, Seitova, Alma, De Souza, Mariana Laureano, Augeri, David, Halabelian, Levon, Siekierka, John, Rotella, David P., Gordon, John, Childers, Wayne E., Grier, Mark C., Staker, Bart L., Roberge, Jacques Y., Bhanot, Purnima

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Estrogen receptor antagonists are anti-cryptococcal agents that directly bind EF hand proteins and synergize with fluconazole in vivo von Butts, Arielle, Koselny, Kristy, Chabrier-Roselló, Yeissa, Semighini, Camile P, Brown, Jessica C S, Wang, Xuying, Annadurai, Sivakumar, DiDone, Louis, Tabroff, Julie, Childers, Jr, Wayne E, Abou-Gharbia, Magid, Wellington, Melanie, Cardenas, Maria E, Madhani, Hiten D, Heitman, Joseph, Krysan, Damian J

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Non-NAD-like PARP-1 inhibitors in prostate cancer treatment von Karpova, Yaroslava, Wu, Chao, Divan, Ali, McDonnell, Mark E., Hewlett, Elizabeth, Makhov, Peter, Gordon, John, Ye, Min, Reitz, Allen B., Childers, Wayne E., Skorski, Tomasz, Kolenko, Vladimir, Tulin, Alexei V.

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Correction to “Structure–Activity Relationship of a Pyrrole Based Series of PfPKG Inhibitors as Anti-Malarials” von Gilleran, John A., Ashraf, Kutub, Delvillar, Melvin, Eck, Tyler, Fondekar, Raheel, Miller, Edward B., Hutchinson, Ashley, Dong, Aiping, Seitova, Alma, De Souza, Mariana Laureano, Augeri, David, Halabelian, Levon, Siekierka, John, Rotella, David P., Gordon, John, Childers, Wayne E., Grier, Mark C., Staker, Bart L., Roberge, Jacques Y., Bhanot, Purnima

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Personalized synthetic lethality induced by targeting RAD52 in leukemias identified by gene mutation and expression profile von Cramer-Morales, Kimberly, Nieborowska-Skorska, Margaret, Scheibner, Kara, Padget, Michelle, Irvine, David A., Sliwinski, Tomasz, Haas, Kimberly, Lee, Jaewoong, Geng, Huimin, Roy, Darshan, Slupianek, Artur, Rassool, Feyruz V., Wasik, Mariusz A., Childers, Wayne, Copland, Mhairi, Müschen, Markus, Civin, Curt I., Skorski, Tomasz

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Discovery of Innovative Therapeutics: Today’s Realities and Tomorrow’s Vision. 1. Criticisms Faced by the Pharmaceutical Industry von Abou-Gharbia, Magid, Childers, Wayne E

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Identification of a Small Molecule Inhibitor of RAD52 by Structure-Based Selection von Sullivan, Katherine, Cramer-Morales, Kimberly, McElroy, Daniel L, Ostrov, David A, Haas, Kimberly, Childers, Wayne, Hromas, Robert, Skorski, Tomasz

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Discovery of a small-molecule inhibitor that traps Polθ on DNA and synergizes with PARP inhibitors von Fried, William, Tyagi, Mrityunjay, Minakhin, Leonid, Chandramouly, Gurushankar, Tredinnick, Taylor, Ramanjulu, Mercy, Auerbacher, William, Calbert, Marissa, Rusanov, Timur, Hoang, Trung, Borisonnik, Nikita, Betsch, Robert, Krais, John J., Wang, Yifan, Vekariya, Umeshkumar M., Gordon, John, Morton, George, Kent, Tatiana, Skorski, Tomasz, Johnson, Neil, Childers, Wayne, Chen, Xiaojiang S., Pomerantz, Richard T.

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Ceftriaxone and MC-100093 mitigate fentanyl-induced cardiac injury in mice: Preclinical investigation of its underlying molecular mechanisms von AlAsmari, Abdullah F., Alshehri, Mohammed M., Ali, Nemat, AlAsmari, Fawaz, Sari, Youssef, Childers, Wayne E., Abou-Gharbia, Magid, Alharbi, Metab, Elnagar, Doaa M., AL-Qahtani, Wejdan S.

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Ribosome-Templated Azide–Alkyne Cycloadditions: Synthesis of Potent Macrolide Antibiotics by In Situ Click Chemistry von Glassford, Ian, Teijaro, Christiana N, Daher, Samer S, Weil, Amy, Small, Meagan C, Redhu, Shiv K, Colussi, Dennis J, Jacobson, Marlene A, Childers, Wayne E, Buttaro, Bettina, Nicholson, Allen W, MacKerell, Alexander D, Cooperman, Barry S, Andrade, Rodrigo B

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Discovery of novel class of histone deacetylase inhibitors as potential anticancer agents von El-Awady, Raafat, Saleh, Ekram, Hamoudi, Rifat, Ramadan, Wafaa S., Mazitschek, Ralph, Nael, Manal A., Elokely, Khaled M., Abou-Gharbia, Magid, Childers, Wayne E., Srinivasulu, Vunnam, Aloum, Lujain, Menon, Varsha, Al-Tel, Taleb H.

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Novel inhibitors of Staphylococcus aureus RnpA that synergize with mupirocin von Lounsbury, Nicole, Eidem, Tess, Colquhoun, Jennifer, Mateo, George, Abou-Gharbia, Magid, Dunman, Paul M., Childers, Wayne E.

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