Targeting the Warburg Effect in cancer; relationships for 2-arylpyridazinones as inhibitors of the key glycolytic enzyme 6-phosphofructo-2-kinase/2,6-bisphosphatase 3 (PFKFB3) von Brooke, Darby G., van Dam, Ellen M., Watts, Colin K.W., Khoury, Amanda, Dziadek, Marie A., Brooks, Hilary, Graham, Lisa-Jane K., Flanagan, Jack U., Denny, William A.

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EDD Mediates DNA Damage-induced Activation of CHK2 von Henderson, Michelle J., Munoz, Marcia A., Saunders, Darren N., Clancy, Jennifer L., Russell, Amanda J., Williams, Brandi, Pappin, Darryl, Khanna, Kum Kum, Jackson, Stephen P., Sutherland, Robert L., Watts, Colin K.W.

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The E3 Ubiquitin Ligase EDD Regulates S-Phase and G2/M DNA Damage Checkpoints von Munoz, Marcia A., Saunders, Darren N., Henderson, Michelle J., Clancy, Jennifer L., Russell, Amanda J., Lehrbach, Gillian, Musgrove, Elizabeth A., Watts, Colin K.W., Sutherland, Robert L.

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Identification of Novel ERK2 Substrates through Use of an Engineered Kinase and ATP Analogs von Eblen, Scott T., Kumar, N. Vinay, Shah, Kavita, Henderson, Michelle J., Watts, Colin K.W., Shokat, Kevan M., Weber, Michael J.

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Functional Roles of the E3 Ubiquitin Ligase UBR5 in Cancer von Shearer, Robert F, Iconomou, Mary, Watts, Colin K W, Saunders, Darren N

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Lycopene inhibition of cell cycle progression in breast and endometrial cancer cells is associated with reduction in cyclin D levels and retention of p27(Kip1) in the cyclin E-cdk2... von Nahum, A, Hirsch, K, Danilenko, M, Watts, C K, Prall, O W, Levy, J, Sharoni, Y

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Lycopene inhibition of IGF-induced cancer cell growth depends on the level of cyclin D1 von NAHUM, Amit, ZELLER, Lior, DANILENKO, Michael, PRALL, Owen W. J, WATTS, Colin K. W, SUTHERLAND, Robert L, LEVY, Joseph, SHARONI, Yoav

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Estrogen-induced Activation of Cdk4 and Cdk2 during G1-S Phase Progression Is Accompanied by Increased Cyclin D1 Expression and Decreased Cyclin-dependent Kinase Inhibitor Associat... von Prall, O W, Sarcevic, B, Musgrove, E A, Watts, C K, Sutherland, R L

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c-Myc or Cyclin D1 Mimics Estrogen Effects on Cyclin E-Cdk2 Activation and Cell Cycle Reentry von Prall, Owen W. J., Rogan, Eileen M., Musgrove, Elizabeth A., Watts, Colin K. W., Sutherland, Robert L.

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Edd, the Murine Hyperplastic Disc Gene, Is Essential for Yolk Sac Vascularization and Chorioallantoic Fusion von Saunders, Darren N., Hird, Samantha L., Withington, Sarah L., Dunwoodie, Sally L., Henderson, Michelle J., Biben, Christine, Sutherland, Robert L., Ormandy, Christopher J., Watts, Colin K. W.

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EDD, the human orthologue of the hyperplastic discs tumour suppressor gene, is amplified and overexpressed in cancer von CLANCY, Jennifer L, HENDERSON, Michelle J, BRADY, Ged, OLOPADE, Olufunmilayo I, WOOLLATT, Erica, DAVIES, Michael J, SEGARA, Davendra, HACKER, Neville F, HENSHALL, Susan M, SUTHERLAND, Robert L, WATTS, Colin K. W, RUSSELL, Amanda J, ANDERSON, David W, BOVA, Ronaldo J, CAMPBELL, Ian G, CHOONG, David Y. H, MACDONALD, Graeme A, MANN, Graham J, NOLAN, Tania

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Putative tumor suppressor EDD interacts with and up‐regulates APC von Ohshima, Ryuichi, Ohta, Tomohiko, Wu, Wenwen, Koike, Ayaka, Iwatani, Tsuguo, Henderson, Michelle, Watts, Colin K. W., Otsubo, Takehito

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Professor Robert Sutherland FAA, AO (1947–2012) von Watts, Colin K.W., Daly, Roger J.

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EDD, the Human Hyperplastic Discs Protein, Has a Role in Progesterone Receptor Coactivation and Potential Involvement in DNA Damage Response von Henderson, Michelle J., Russell, Amanda J., Hird, Samantha, Muñoz, Marcia, Clancy, Jennifer L., Lehrbach, Gillian M., Calanni, Sophina T., Jans, David A., Sutherland, Robert L., Watts, Colin K.W.

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Identification of a human HECT family protein with homology to the Drosophila tumor suppressor gene hyperplastic discs von CALLAGHAN, M. J, RUSSELL, A. J, WOOLLATT, E, SUTHERLAND, G. R, SUTHERLAND, R. L, WATTS, C. K. W

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Growth factor, steroid, and steroid antagonist regulation of cyclin gene expression associated with changes in T-47D human breast cancer cell cycle progression von MUSGROVE, E. A, HAMILTON, J. A, LEE, C. S. L, SWEENEY, K. J. E, WATTS, C. K. W, SUTHERLAND, R. L

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Inhibition of AP-1 Binding and Transcription by Gold and Selenium Involving Conserved Cysteine Residues in Jun and Fos von Handel, Malcolm L., Colin K. W. Watts, DeFazio, Anna, Day, Richard O., Sutherland, Robert L.

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The E3 Ubiquitin Ligase EDD Regulates S-Phase and G 2 /M DNA Damage Checkpoints von Munoz, Marcia A., Saunders, Darren N., Henderson, Michelle J., Clancy, Jennifer L., Russell, Amanda J., Lehrbach, Gillian, Musgrove, Elizabeth A., Watts, Colin K.W., Sutherland, Robert L.

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Estrogen and progestin regulation of cell cycle progression von Sutherland, R L, Prall, O W, Watts, C K, Musgrove, E A

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Identification of PRG1, A Novel Progestin-Responsive Gene with Sequence Homology to 6-Phosphofructo-2-Kinase/Fructose- 2,6-Bisphosphatase von Hamilton, Jenny A, Callaghan, Michelle J, Sutherland, Robert L, Watts, Colin K. W

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