Patterns in breast cancer staging imaging: Are we choosing wisely? von Barlow, Brett, Williams, Courtney, Gilbert, Aidan, Watkins, Stacey M, Rocque, Gabrielle Betty

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Association of a combined panel of tumor infiltrating lymphocytes, plasma cells, and macrophages with recurrence of localized clear cell (cc) renal cell carcinoma (RCC) undergoing... von Ghatalia, Pooja, Gordetsky, Jennifer, Bae, Sejong, Watkins, Stacey M, Sudarshan, Sunil, Naik, Gurudatta, Sonpavde, Guru

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EGF Receptor Ligands Differentially Promote the Migration and Invasion of Malignant Peripheral Nerve Sheath Tumor Cells von Byer, Stephanie, Eckert, Jenell M, Watkins, Stacey M, Carroll, Steven L

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Analysis of protein-coding genetic variation in 60,706 humans von Lek, Monkol, Karczewski, Konrad J., Minikel, Eric V., Samocha, Kaitlin E., Banks, Eric, Fennell, Timothy, O’Donnell-Luria, Anne H., Ware, James S., Hill, Andrew J., Cummings, Beryl B., Tukiainen, Taru, Birnbaum, Daniel P., Kosmicki, Jack A., Duncan, Laramie E., Estrada, Karol, Zhao, Fengmei, Zou, James, Pierce-Hoffman, Emma, Berghout, Joanne, Cooper, David N., Deflaux, Nicole, DePristo, Mark, Do, Ron, Flannick, Jason, Fromer, Menachem, Gauthier, Laura, Goldstein, Jackie, Gupta, Namrata, Howrigan, Daniel, Kiezun, Adam, Kurki, Mitja I., Moonshine, Ami Levy, Natarajan, Pradeep, Orozco, Lorena, Peloso, Gina M., Poplin, Ryan, Rivas, Manuel A., Ruano-Rubio, Valentin, Rose, Samuel A., Ruderfer, Douglas M., Shakir, Khalid, Stenson, Peter D., Stevens, Christine, Thomas, Brett P., Tiao, Grace, Tusie-Luna, Maria T., Weisburd, Ben, Won, Hong-Hee, Yu, Dongmei, Altshuler, David M., Ardissino, Diego, Boehnke, Michael, Danesh, John, Donnelly, Stacey, Elosua, Roberto, Florez, Jose C., Gabriel, Stacey B., Getz, Gad, Glatt, Stephen J., Hultman, Christina M., Kathiresan, Sekar, Laakso, Markku, McCarroll, Steven, McCarthy, Mark I., McGovern, Dermot, McPherson, Ruth, Neale, Benjamin M., Palotie, Aarno, Purcell, Shaun M., Saleheen, Danish, Scharf, Jeremiah M., Sklar, Pamela, Sullivan, Patrick F., Tuomilehto, Jaakko, Tsuang, Ming T., Watkins, Hugh C., Wilson, James G., Daly, Mark J., MacArthur, Daniel G.

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Disruption of astrocyte–vascular coupling and the blood–brain barrier by invading glioma cells von Watkins, Stacey, Robel, Stefanie, Kimbrough, Ian F., Robert, Stephanie M., Ellis-Davies, Graham, Sontheimer, Harald

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Diagnostic Yield and Clinical Utility of Sequencing Familial Hypercholesterolemia Genes in Patients With Severe Hypercholesterolemia von Khera, Amit V., MD, Won, Hong-Hee, PhD, Peloso, Gina M., PhD, Lawson, Kim S., MS, Bartz, Traci M., MS, Deng, Xuan, MSc, van Leeuwen, Elisabeth M, Natarajan, Pradeep, MD, MMSc, Emdin, Connor A., HBSc, Bick, Alexander G., PhD, Morrison, Alanna C., PhD, Brody, Jennifer A., BA, Gupta, Namrata, PhD, Nomura, Akihiro, MD, Kessler, Thorsten, MD, Duga, Stefano, PhD, Bis, Joshua C., PhD, van Duijn, Cornelia M., PhD, Cupples, L. Adrienne, PhD, Psaty, Bruce, MD, PhD, Rader, Daniel J., MD, Danesh, John, DPhil, Schunkert, Heribert, MD, McPherson, Ruth, MD, Farrall, Martin, MD, Watkins, Hugh, MD, PhD, Lander, Eric, PhD, Wilson, James G., MD, Correa, Adolfo, MD, PhD, Boerwinkle, Eric, PhD, Merlini, Piera Angelica, MD, Ardissino, Diego, MD, Saleheen, Danish, MBBS, PhD, Gabriel, Stacey, PhD, Kathiresan, Sekar, MD

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Roll-out of the Global Burden of Animal Diseases programme von Rushton, J, Huntington, B, Gilbert, W, Herrero, M, Torgerson, P R, Shaw, A P M, Bruce, M, Marsh, T L, Pendell, D L, Bernardo, T M, Stacey, D, Grace, D, Watkins, K, Bondad-Reantaso, M, Devleesschauwer, B, Pigott, D M, Stone, M, Mesenhowski, S

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The AKT2/SIRT5/TFEB pathway as a potential therapeutic target in non-neovascular AMD von Ghosh, Sayan, Sharma, Ruchi, Bammidi, Sridhar, Koontz, Victoria, Nemani, Mihir, Yazdankhah, Meysam, Kedziora, Katarzyna M., Stolz, Donna Beer, Wallace, Callen T., Yu-Wei, Cheng, Franks, Jonathan, Bose, Devika, Shang, Peng, Ambrosino, Helena M., Dutton, James R., Geng, Zhaohui, Montford, Jair, Ryu, Jiwon, Rajasundaram, Dhivyaa, Hose, Stacey, Sahel, José-Alain, Puertollano, Rosa, Finkel, Toren, Zigler, J. Samuel, Sergeev, Yuri, Watkins, Simon C., Goetzman, Eric S., Ferrington, Deborah A., Flores-Bellver, Miguel, Kaarniranta, Kai, Sodhi, Akrit, Bharti, Kapil, Handa, James T., Sinha, Debasish

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A structural variation reference for medical and population genetics von Collins, Ryan L., Brand, Harrison, Karczewski, Konrad J., Zhao, Xuefang, Alföldi, Jessica, Francioli, Laurent C., Khera, Amit V., Lowther, Chelsea, Gauthier, Laura D., Wang, Harold, Watts, Nicholas A., Solomonson, Matthew, O’Donnell-Luria, Anne, Baumann, Alexander, Munshi, Ruchi, Walker, Mark, Whelan, Christopher W., Huang, Yongqing, Brookings, Ted, Sharpe, Ted, Stone, Matthew R., Valkanas, Elise, Fu, Jack, Tiao, Grace, Laricchia, Kristen M., Ruano-Rubio, Valentin, Stevens, Christine, Gupta, Namrata, Cusick, Caroline, Margolin, Lauren, Taylor, Kent D., Lin, Henry J., Rich, Stephen S., Post, Wendy S., Chen, Yii-Der Ida, Rotter, Jerome I., Nusbaum, Chad, Philippakis, Anthony, Lander, Eric, Gabriel, Stacey, Neale, Benjamin M., Kathiresan, Sekar, Daly, Mark J., Banks, Eric, MacArthur, Daniel G., Talkowski, Michael E.

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Global Burden of Animal Diseases: a novel approach to understanding and managing disease in livestock and aquaculture von Huntington, B., Bernardo, T. M., Bondad-Reantaso, M., Bruce, M., Devleesschauwer, B., Gilbert, W., Grace, D., Havelaar, A., Herrero, M., Marsh, T. L., Mesenhowski, S., Pendell, D., Pigott, D., Shaw, A. P., Stacey, D., Stone, M., Torgerson, P., Watkins, K., Wieland, B., Rushton, J.

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COVID-19 Vaccine Breakthrough Infections Reported to CDC - United States, January 1-April 30, 2021 von Birhane, Meseret, Bressler, Sara, Chang, Gregory, Clark, Thomas, Dorough, Layne, Fischer, Marc, Watkins, Louise Francois, Goldstein, Jason M., Kugeler, Kiersten, Langley, Gayle, Lecy, Kristin, Martin, Stacey, Medalla, Felicita, Mitruka, Kiren, Nolen, Leisha, Sadigh, Katrin, Spratling, Robin, Thompson, Gail, Trujillo, Alma

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Programmed Death-1 Ligand 2-Mediated Regulation of the PD-L1 to PD-1 Axis Is Essential for Establishing CD4+ T Cell Immunity von Karunarathne, Deshapriya S., Horne-Debets, Joshua M., Huang, Johnny X., Faleiro, Rebecca, Leow, Chiuan Yee, Amante, Fiona, Watkins, Thomas S., Miles, John J., Dwyer, Patrick J., Stacey, Katryn J., Yarski, Michael, Poh, Chek Meng, Lee, Jason S., Cooper, Matthew A., Rénia, Laurent, Richard, Derek, McCarthy, James S., Sharpe, Arlene H., Wykes, Michelle N.

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Quantifying prion disease penetrance using large population control cohorts von Minikel, EV, Vallabh, SM, Lek, M, Estrada, K, Samocha, KE, Sathirapongsasuti, JF, McLean, CY, Tung, JY, Yu, LPC, Gambetti, P, Blevins, J, Zhang, SL, Cohen, Y, Chen, W, Yamada, M, Hamaguchi, T, Sanjo, N, Mizusawa, H, Nakamura, Y, Kitamoto, T, Collins, SJ, Boyd, A, Will, RG, Knight, R, Ponto, C, Zerr, I, Kraus, TFJ, Eigenbrod, S, Giese, A, Calero, M, de Pedro-Cuesta, J, Haik, S, Laplanche, JL, Bouaziz-Amar, E, Brandel, JP, Capellari, S, Parchi, P, Poleggi, A, Ladogana, A, O'Donnell-Luria, AH, Karczewski, KJ, Marshall, JL, Boehnke, M, Laakso, M, Mohlke, KL, Kahler, A, Chambert, K, McCarroll, S, Sullivan, PF, Hultman, CM, Purcell, SM, Sklar, P, van der Lee, SJ, Rozemuller, A, Jansen, C, Hofman, A, Kraaij, R, van Rooij, JGJ, Ikram, MA, Uitterlinden, AG, van Duijn, CM, Daly, MJ, MacArthur, DG

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Transcript expression-aware annotation improves rare variant interpretation von Cummings, Beryl B., Karczewski, Konrad J., Kosmicki, Jack A., Seaby, Eleanor G., Watts, Nicholas A., Singer-Berk, Moriel, Mudge, Jonathan M., Karjalainen, Juha, Satterstrom, F. Kyle, O’Donnell-Luria, Anne H., Poterba, Timothy, Seed, Cotton, Solomonson, Matthew, Alföldi, Jessica, Daly, Mark J., MacArthur, Daniel G.

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Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction von Do, Ron, Stitziel, Nathan O., Won, Hong-Hee, Jørgensen, Anders Berg, Duga, Stefano, Angelica Merlini, Pier, Kiezun, Adam, Farrall, Martin, Goel, Anuj, Zuk, Or, Guella, Illaria, Asselta, Rosanna, Lange, Leslie A., Peloso, Gina M., Auer, Paul L., Girelli, Domenico, Martinelli, Nicola, Farlow, Deborah N., DePristo, Mark A., Roberts, Robert, Stewart, Alexander F. R., Saleheen, Danish, Danesh, John, Epstein, Stephen E., Sivapalaratnam, Suthesh, Kees Hovingh, G., Kastelein, John J., Samani, Nilesh J., Schunkert, Heribert, Erdmann, Jeanette, Shah, Svati H., Kraus, William E., Davies, Robert, Nikpay, Majid, Johansen, Christopher T., Wang, Jian, Hegele, Robert A., Hechter, Eliana, Marz, Winfried, Kleber, Marcus E., Huang, Jie, Johnson, Andrew D., Li, Mingyao, Burke, Greg L., Gross, Myron, Liu, Yongmei, Assimes, Themistocles L., Heiss, Gerardo, Lange, Ethan M., Folsom, Aaron R., Taylor, Herman A., Olivieri, Oliviero, Hamsten, Anders, Clarke, Robert, Reilly, Dermot F., Yin, Wu, Rivas, Manuel A., Donnelly, Peter, Rossouw, Jacques E., Psaty, Bruce M., Herrington, David M., Wilson, James G., Rich, Stephen S., Bamshad, Michael J., Tracy, Russell P., Adrienne Cupples, L., Rader, Daniel J., Reilly, Muredach P., Spertus, John A., Cresci, Sharon, Hartiala, Jaana, Wilson Tang, W. H., Hazen, Stanley L., Allayee, Hooman, Reiner, Alex P., Carlson, Christopher S., Kooperberg, Charles, Jackson, Rebecca D., Boerwinkle, Eric, Lander, Eric S., Schwartz, Stephen M., Siscovick, David S., McPherson, Ruth, Tybjaerg-Hansen, Anne, Abecasis, Goncalo R., Watkins, Hugh, Nickerson, Deborah A., Ardissino, Diego, Sunyaev, Shamil R., O'Donnell, Christopher J., Altshuler, David, Gabriel, Stacey, Kathiresan, Sekar

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Evaluating drug targets through human loss-of-function genetic variation von Minikel, Eric Vallabh, Karczewski, Konrad J., Martin, Hilary C., Cummings, Beryl B., Whiffin, Nicola, Rhodes, Daniel, Alföldi, Jessica, Trembath, Richard C., van Heel, David A., Daly, Mark J., Schreiber, Stuart L., MacArthur, Daniel G.

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The role of lipocalin-2 in age-related macular degeneration (AMD) von Ghosh, Sayan, Stepicheva, Nadezda, Yazdankhah, Meysam, Shang, Peng, Watson, Alan M., Hose, Stacey, Liu, Haitao, Weiss, Joseph, Zigler, J. Samuel, Valapala, Mallika, Watkins, Simon C., Sinha, Debasish

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Landscape of multi-nucleotide variants in 125,748 human exomes and 15,708 genomes von Wang, Qingbo, Pierce-Hoffman, Emma, Cummings, Beryl B., Alföldi, Jessica, Francioli, Laurent C., Gauthier, Laura D., Hill, Andrew J., O’Donnell-Luria, Anne H., Karczewski, Konrad J., MacArthur, Daniel G.

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DNA Sequence Variation in ACVR1C Encoding the Activin Receptor-Like Kinase 7 Influences Body Fat Distribution and Protects Against Type 2 Diabetes von Emdin, Connor A, Khera, Amit V, Aragam, Krishna, Haas, Mary, Chaffin, Mark, Klarin, Derek, Natarajan, Pradeep, Bick, Alexander, Zekavat, Seyedeh M, Nomura, Akihiro, Ardissino, Diego, Wilson, James G, Schunkert, Heribert, McPherson, Ruth, Watkins, Hugh, Elosua, Roberto, Bown, Matthew J, Samani, Nilesh J, Baber, Usman, Erdmann, Jeanette, Gupta, Namrata, Danesh, John, Saleheen, Danish, Gabriel, Stacey, Kathiresan, Sekar

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Analysis of predicted loss-of-function variants in UK Biobank identifies variants protective for disease von Emdin, Connor A., Khera, Amit V., Chaffin, Mark, Klarin, Derek, Natarajan, Pradeep, Aragam, Krishna, Haas, Mary, Bick, Alexander, Zekavat, Seyedeh M., Nomura, Akihiro, Ardissino, Diego, Wilson, James G., Schunkert, Heribert, McPherson, Ruth, Watkins, Hugh, Elosua, Roberto, Bown, Matthew J., Samani, Nilesh J., Baber, Usman, Erdmann, Jeanette, Gupta, Namrata, Danesh, John, Chasman, Daniel, Ridker, Paul, Denny, Joshua, Bastarache, Lisa, Lichtman, Judith H., D’Onofrio, Gail, Mattera, Jennifer, Spertus, John A., Sheu, Wayne H.-H., Taylor, Kent D., Psaty, Bruce M., Rich, Stephen S., Post, Wendy, Rotter, Jerome I., Chen, Yii-Der Ida, Krumholz, Harlan, Saleheen, Danish, Gabriel, Stacey, Kathiresan, Sekar

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