312 Efficacy and Safety of ASP7147, a Bombesin-2 Receptor Antagonist, in Diarrhea-Predominant Irritable Bowel Syndrome (IBS-D): Results of a Multicenter, Double-Blind, Placebo-Cont... von Lembo, Anthony, Huber, James, Schinagl, Robert M, Waters, Stephen J, Harris, M. Scott

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ATM-dependent CHK2 Activation Induced by Anticancer Agent, Irofulven von Wang, Jian, Wiltshire, Timothy, Wang, Yutian, Mikell, Carmenza, Burks, Julian, Cunningham, Cynthia, Van Laar, Emily S., Waters, Stephen J., Reed, Eddie, Wang, Weixin

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Caspase-mediated apoptosis and caspase-independent cell death induced by irofulven in prostate cancer cells von Liang, Huiyun, Salinas, Richard A, Leal, Belinda Z, Kosakowska-Cholody, Teresa, Michejda, Christopher J, Waters, Stephen J, Herman, Terence S, Woynarowski, Jan M, Woynarowska, Barbara A

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Inhibiting Tumor Growth by Targeting Tumor Vasculature with Galectin-1 Antagonist Anginex Conjugated to the Cytotoxic Acylfulvene, 6-Hydroxylpropylacylfulvene von Dings, Ruud P. M, Van Laar, Emily S, Loren, Melissa, Webber, Jeremy, Zhang, Yan, Waters, Stephen J, MacDonald, John R, Mayo, Kevin H

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Ovarian tumor growth regression using a combination of vascular targeting agents anginex or topomimetic 0118 and the chemotherapeutic irofulven von Dings, Ruud P.M, Laar, Emily S. Van, Webber, Jeremy, Zhang, Yan, Griffin, Robert J, Waters, Stephen J, MacDonald, John R, Mayo, Kevin H

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Activity of Irofulven against Human Pancreatic Carcinoma Cell Lines In Vitro and In Vivo von VAN LAAR, Emily S, ROTH, Stephanie, WEITMAN, Steven, MACDONALD, John R, WATERS, Stephen J

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Cell cycle effects and induction of premitotic apoptosis by irofulven in synchronized cancer cells von Woynarowski, Jan M., Woynarowska, Barbara A., Trevino, Alex V., Salinas, Richard, Herman, Terence S., Waters, Stephen J., MacDonald, John R.

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Marked activity of Irofulven toward human carcinoma cells: Comparison with cisplatin and ecteinascidin von POINDESSOUS, Virginie, KOEPPEL, Florence, RAYMOND, Eric, COMISSO, Martine, WATERS, Stephen J, LARSEN, Annette K

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Characterizations of irofulven cytotoxicity in combination with cisplatin and oxaliplatin in human colon, breast, and ovarian cancer cells von SEROVA, Maria, CALVO, Fabien, LOKIEC, Francois, KOEPPEL, Florence, POINDESSOUS, Virginie, LARSEN, Annette K, VAN. LAAR, Emily S, WATERS, Stephen J, CVITKOVIC, Esteban, RAYMOND, Eric

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Apoptosis induction by the dual-action DNA- and protein-reactive antitumor drug irofulven is largely Bcl-2-independent von Herzig, Maryanne C.S, Trevino, Alex V, Liang, Huiyun, Salinas, Richard, Waters, Stephen J, MacDonald, John R, Woynarowska, Barbara A, Woynarowski, Jan M

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Structure−Activity Studies of Antitumor Agent Irofulven (Hydroxymethylacylfulvene) and Analogues von McMorris, Trevor C, Yu, Jian, Lira, Ricardo, Dawe, Robin, MacDonald, John R, Waters, Stephen J, Estes, Leita A, Kelner, Michael J

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Antitumor activity of irofulven monotherapy and in combination with mitoxantrone or docetaxel against human prostate cancer models von Van Laar, Emily S., Weitman, Steven, MacDonald, John R., Waters, Stephen J.

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Activity of irofulven (6-hydroxymethylacylfulvene) in the treatment of glioblastoma multiforme-derived xenografts in athymic mice von FRIEDMAN, Henry S, KEIR, Stephen T, HOUGHTON, Peter J, LAWLESS, Amy A, BIGNER, Darell D, WATERS, Stephen J

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Changes in prostate-specific antigen (PSA) level correlate with growth inhibition of prostate cancer cells treated in vitro with a novel anticancer drug, irofulven von WOYNAROWSKA, Barbara A, HIGDON, Arlene L, MUNOZ, Ruben M, BUSHONG, Perry, WATERS, Stephen J

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MAC of 1–653 in Beagle Dogs and New Zealand White Rabbits von Doorley, Brian M., Waters, Stephen J., Terrell, Ross C., Robinson, James L

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Marked Activity of Irofulven toward Human Carcinoma Cells von Virginie Poindessous, Florence Koeppel, Eric Raymond, Martine Comisso, Stephen J. Waters, Annette K. Larsen

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MGI 114 : Augmentation of antitumor activity when combined with topotecan von WEITMAN, S, BARRERA, H, MOORE, R, GONZALEZ, C, MARTY, J, HILSENBECK, S, MACDONALD, J. R, WATERS, S. J, VON HOFF, D

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Duration of Opioid Antagonism by Nalmefene and Naloxone in the Dog: An Integrated Pharmacokinetic/Pharmacodynamic Comparison von Veng‐Pedersen, Peter, Wilhelm, Jeffrey A., Zakszewski, Thomas B., Osifchin, Edward, Waters, Stephen J.

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The DOT1L inhibitor pinometostat reduces H3K79 methylation and has modest clinical activity in adult acute leukemia von Stein, Eytan M., Garcia-Manero, Guillermo, Rizzieri, David A., Tibes, Raoul, Berdeja, Jesus G., Savona, Michael R., Jongen-Lavrenic, Mojca, Altman, Jessica K., Thomson, Blythe, Blakemore, Stephen J., Daigle, Scott R., Waters, Nigel J., Suttle, A. Benjamin, Clawson, Alicia, Pollock, Roy, Krivtsov, Andrei, Armstrong, Scott A., DiMartino, Jorge, Hedrick, Eric, Löwenberg, Bob, Tallman, Martin S.

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Master transcription factors form interconnected circuitry and orchestrate transcriptional networks in oesophageal adenocarcinoma von Chen, Li, Huang, Moli, Plummer, Jasmine, Pan, Jian, Jiang, Yan Yi, Yang, Qian, Silva, Tiago Chedraoui, Gull, Nicole, Chen, Stephanie, Ding, Ling Wen, An, Omer, Yang, Henry, Cheng, Yulan, Said, Jonathan W, Doan, Ngan, Dinjens, Winand NM, Waters, Kevin M, Tuli, Richard, Gayther, Simon A, Klempner, Samuel J, Berman, Benjamin P, Meltzer, Stephen J, Lin, De-Chen, Koeffler, H Phillip

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