A Role for Fragment-Based Drug Design in Developing Novel Lead Compounds for Central Nervous System Targets von Wasko, Michael J, Pellegrene, Kendy A, Madura, Jeffry D, Surratt, Christopher K

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DARK Classics in Chemical Neuroscience: Ibogaine von Wasko, Michael J, Witt-Enderby, Paula A, Surratt, Christopher K

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Dopamine Transporter Dynamics of N -Substituted Benztropine Analogs with Atypical Behavioral Effects von Hong, Weimin C, Wasko, Michael J, Wilkinson, Derek S, Hiranita, Takato, Li, Libin, Hayashi, Shuichiro, Snell, David B, Madura, Jeffry D, Surratt, Christopher K, Katz, Jonathan L

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In Silico Discovery and Pharmacological Analysis of Potential Ligands Targeting the Serotonin Transporter von Wasko, Michael J., Witt‐Enderby, Paula A.

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In Silico Molecular Dynamics Analysis of Dopamine Transporter Conformational Preference as a Function of Occupancy with Inhibitors of Low Abuse Potential von Wasko, Michael J., Madura, Jeffry D., Hong, Weimin C., Katz, Jonathan L., Surratt, Christopher K.

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Fragment‐Based Drug Design with CNS Therapeutic Targets von Surratt, Christopher K., Pellegrene, Kendy A., Wasko, Michael J., Jean, Bernandie K., Madura, Jeffry D.

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Molecular mechanisms underlying genotype‐dependent responses to dietary restriction von Schleit, Jennifer, Johnson, Simon C., Bennett, Christopher F., Simko, Marissa, Trongtham, Natalie, Castanza, Anthony, Hsieh, Edward J., Moller, Richard M., Wasko, Brian M., Delaney, Joe R., Sutphin, George L., Carr, Daniel, Murakami, Christopher J., Tocchi, Autumn, Xian, Bo, Chen, Weiyang, Yu, Tao, Goswami, Sarani, Higgins, Sean, Holmberg, Mollie, Jeong, Ki‐Soo, Kim, Jin R., Klum, Shannon, Liao, Eric, Lin, Michael S., Lo, Winston, Miller, Hillary, Olsen, Brady, Peng, Zhao J., Pollard, Tom, Pradeep, Prarthana, Pruett, Dillon, Rai, Dilreet, Ros, Vanessa, Singh, Minnie, Spector, Benjamin L., Wende, Helen Vander, An, Elroy H., Fletcher, Marissa, Jelic, Monika, Rabinovitch, Peter S., MacCoss, Michael J., Han, Jing‐Dong J., Kennedy, Brian K., Kaeberlein, Matt

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Tumour-selective activity of RAS-GTP inhibition in pancreatic cancer von Wasko, Urszula N., Jiang, Jingjing, Dalton, Tanner C., Curiel-Garcia, Alvaro, Edwards, A. Cole, Wang, Yingyun, Lee, Bianca, Orlen, Margo, Tian, Sha, Stalnecker, Clint A., Drizyte-Miller, Kristina, Menard, Marie, Dilly, Julien, Sastra, Stephen A., Palermo, Carmine F., Hasselluhn, Marie C., Decker-Farrell, Amanda R., Chang, Stephanie, Jiang, Lingyan, Wei, Xing, Yang, Yu C., Helland, Ciara, Courtney, Haley, Gindin, Yevgeniy, Muonio, Karl, Zhao, Ruiping, Kemp, Samantha B., Clendenin, Cynthia, Sor, Rina, Vostrejs, William P., Hibshman, Priya S., Amparo, Amber M., Hennessey, Connor, Rees, Matthew G., Ronan, Melissa M., Roth, Jennifer A., Brodbeck, Jens, Tomassoni, Lorenzo, Bakir, Basil, Socci, Nicholas D., Herring, Laura E., Barker, Natalie K., Wang, Junning, Cleary, James M., Wolpin, Brian M., Chabot, John A., Kluger, Michael D., Manji, Gulam A., Tsai, Kenneth Y., Sekulic, Miroslav, Lagana, Stephen M., Califano, Andrea, Quintana, Elsa, Wang, Zhengping, Smith, Jacqueline A. M., Holderfield, Matthew, Wildes, David, Lowe, Scott W., Badgley, Michael A., Aguirre, Andrew J., Vonderheide, Robert H., Stanger, Ben Z., Baslan, Timour, Der, Channing J., Singh, Mallika, Olive, Kenneth P.

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Defining the impact of mutation accumulation on replicative lifespan in yeast using cancer-associated mutator phenotypes von Lee, Mitchell B., Dowsett, Ian T., Carr, Daniel T., Wasko, Brian M., Stanton, Sarah G., Chung, Michael S., Ghodsian, Niloufar, Bode, Anna, Kiflezghi, Michael G., Uppal, Priya A., Grayden, Katherine A., Elala, Yordanos C., Tang, Thao T., Tran, Ngoc H. B., Tran, Thu H. B., Diep, Anh B., Hope, Michael, Promislow, Daniel E. L., Kennedy, Scott R., Kaeberlein, Matt, Herr, Alan J.

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Towards advancing scientific knowledge of climate change impacts on short-duration rainfall extremes von Fowler, Hayley J, Ali, Haider, Allan, Richard P, Ban, Nikolina, Barbero, Renaud, Berg, Peter, Blenkinsop, Stephen, Cabi, Nalan Senol, Chan, Steven, Dale, Murray, Dunn, Robert J H, Ekström, Marie, Evans, Jason P, Fosser, Giorgia, Golding, Brian, Guerreiro, Selma B, Hegerl, Gabriele C, Kahraman, Abdullah, Kendon, Elizabeth J, Lenderink, Geert, Lewis, Elizabeth, Li, Xiaofeng, O'Gorman, Paul A, Orr, Harriet G, Peat, Katy L, Prein, Andreas F, Pritchard, David, Schär, Christoph, Sharma, Ashish, Stott, Peter A, Villalobos-Herrera, Roberto, Villarini, Gabriele, Wasko, Conrad, Wehner, Michael F, Westra, Seth, Whitford, Anna

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Prominent Anterior Inferior Iliac Spine Morphologies Are Common in Patients with Acetabular Dysplasia Undergoing Periacetabular Osteotomy von Nestorovski, Douglas, Wasko, Marcin, Fowler, Lucas M., Harris, Michael D., Clohisy, John C., Nepple, Jeffrey J.

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Author Correction: Tumour-selective activity of RAS-GTP inhibition in pancreatic cancer von Wasko, Urszula N., Jiang, Jingjing, Dalton, Tanner C., Curiel-Garcia, Alvaro, Edwards, A. Cole, Wang, Yingyun, Lee, Bianca, Orlen, Margo, Tian, Sha, Stalnecker, Clint A., Drizyte-Miller, Kristina, Menard, Marie, Dilly, Julien, Sastra, Stephen A., Palermo, Carmine F., Hasselluhn, Marie C., Decker-Farrell, Amanda R., Chang, Stephanie, Jiang, Lingyan, Wei, Xing, Yang, Yu C., Helland, Ciara, Courtney, Haley, Gindin, Yevgeniy, Muonio, Karl, Zhao, Ruiping, Kemp, Samantha B., Clendenin, Cynthia, Sor, Rina, Vostrejs, William P., Hibshman, Priya S., Amparo, Amber M., Hennessey, Connor, Rees, Matthew G., Ronan, Melissa M., Roth, Jennifer A., Brodbeck, Jens, Tomassoni, Lorenzo, Bakir, Basil, Socci, Nicholas D., Herring, Laura E., Barker, Natalie K., Wang, Junning, Cleary, James M., Wolpin, Brian M., Chabot, John A., Kluger, Michael D., Manji, Gulam A., Tsai, Kenneth Y., Sekulic, Miroslav, Lagana, Stephen M., Califano, Andrea, Quintana, Elsa, Wang, Zhengping, Smith, Jacqueline A. M., Holderfield, Matthew, Wildes, David, Lowe, Scott W., Badgley, Michael A., Aguirre, Andrew J., Vonderheide, Robert H., Stanger, Ben Z., Baslan, Timour, Der, Channing J., Singh, Mallika, Olive, Kenneth P.

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Efficacy and safety of tofacitinib monotherapy, tofacitinib with methotrexate, and adalimumab with methotrexate in patients with rheumatoid arthritis (ORAL Strategy): a phase 3b/4,... von Fleischmann, Roy, Prof, Mysler, Eduardo, MD, Hall, Stephen, MD, Kivitz, Alan J, MD, Moots, Robert J, Prof, Luo, Zhen, PhD, DeMasi, Ryan, MD, Soma, Koshika, MD, Zhang, Richard, PhD, Takiya, Liza, PharmD, Tatulych, Svitlana, MD, Mojcik, Christopher, MD, Krishnaswami, Sriram, PhD, Menon, Sujatha, PhD, Smolen, Josef S, Prof

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A Comparison of Etanercept and Methotrexate in Patients with Early Rheumatoid Arthritis von Bathon, Joan M, Martin, Richard W, Fleischmann, Roy M, Tesser, John R, Schiff, Michael H, Keystone, Edward C, Genovese, Mark C, Wasko, Mary Chester, Moreland, Larry W, Weaver, Arthur L, Markenson, Joseph, Finck, Barbara K

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Dietary restriction and mitochondrial function link replicative and chronological aging in Saccharomyces cerevisiae von Delaney, Joe R., Murakami, Christopher, Chou, Annie, Carr, Daniel, Schleit, Jennifer, Sutphin, George L., An, Elroy H., Castanza, Anthony S., Fletcher, Marissa, Goswami, Sarani, Higgins, Sean, Holmberg, Mollie, Hui, Jessica, Jelic, Monika, Jeong, Ki-Soo, Kim, Jin R., Klum, Shannon, Liao, Eric, Lin, Michael S., Lo, Winston, Miller, Hillary, Moller, Richard, Peng, Zhao J., Pollard, Tom, Pradeep, Prarthana, Pruett, Dillon, Rai, Dilreet, Ros, Vanessa, Schuster, Alex, Singh, Minnie, Spector, Benjamin L., Wende, Helen Vander, Wang, Adrienne M., Wasko, Brian M., Olsen, Brady, Kaeberlein, Matt

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Tofacitinib versus Methotrexate in Rheumatoid Arthritis von Lee, Eun Bong, Fleischmann, Roy, Hall, Stephen, Wilkinson, Bethanie, Bradley, John D, Gruben, David, Koncz, Tamas, Krishnaswami, Sriram, Wallenstein, Gene V, Zang, Chuanbo, Zwillich, Samuel H, van Vollenhoven, Ronald F

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Pharmacological reactivation of inactive X-linked Mecp2 in cerebral cortical neurons of living mice von Przanowski, Piotr, Wasko, Urszula, Zheng, Zeming, Yu, Jun, Sherman, Robyn, Zhu, Lihua Julie, McConnell, Michael J., Tushir-Singh, Jogender, Green, Michael R., Bhatnagar, Sanchita

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pH neutralization protects against reduction in replicative lifespan following chronological aging in yeast von Murakami, Christopher, Delaney, Joe R., Chou, Annie, Carr, Daniel, Schleit, Jennifer, Sutphin, George L., An, Elroy H., Castanza, Anthony S., Fletcher, Marissa, Goswami, Sarani, Higgins, Sean, Holmberg, Mollie, Hui, Jessica, Jelic, Monika, Jeong, Ki-Soo, Kim, Jin R., Klum, Shannon, Liao, Eric, Lin, Michael S., Lo, Winston, Miller, Hillary, Moller, Richard, Peng, Zhao J., Pollard, Tom, Pradeep, Prarthana, Pruett, Dillon, Rai, Dilreet, Ros, Vanessa, Schuster, Alex, Singh, Minnie, Spector, Benjamin L., Vander Wende, Helen, Wang, Adrienne M., Wasko, Brian M., Olsen, Brady, Kaeberlein, Matt

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Golimumab in patients with active rheumatoid arthritis after treatment with tumour necrosis factor α inhibitors (GO-AFTER study): a multicentre, randomised, double-blind, placebo-c... von Smolen, Josef S, Prof, Kay, Jonathan, MD, Doyle, Mittie K, MD, Landewé, Robert, MD, Matteson, Eric L, Prof, Wollenhaupt, Jürgen, Prof, Gaylis, Norman, MD, Murphy, Frederick T, MD, Neal, Jeffrey S, MD, Zhou, Yiying, PhD, Visvanathan, Sudha, PhD, Hsia, Elizabeth C, MD, Rahman, Mahboob U, MD

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Loss of vacuolar acidity results in iron-sulfur cluster defects and divergent homeostatic responses during aging in Saccharomyces cerevisiae von Chen, Kenneth L., Ven, Toby N., Crane, Matthew M., Brunner, Matthew L. C., Pun, Adrian K., Helget, Kathleen L., Brower, Katherine, Chen, Dexter E., Doan, Ha, Dillard-Telm, Justin D., Huynh, Ellen, Feng, Yen-Chi, Yan, Zili, Golubeva, Alexandra, Hsu, Roy A., Knight, Raheem, Levin, Jessie, Mobasher, Vesal, Muir, Michael, Omokehinde, Victor, Screws, Corey, Tunali, Esin, Tran, Rachael K., Valdez, Luz, Yang, Edward, Kennedy, Scott R., Herr, Alan J., Kaeberlein, Matt, Wasko, Brian M.

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